专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2012094394A3 METHODS AND COMPOSITIONS FOR ASSESSING AND TREATING ADRENAL DISEASES AND DISORDERS 审中-公开
标题翻译：用于评估和治疗ADRENAL疾病和疾病的方法和组合物
公开(公告)号：WO2012094394A3
公开(公告)日：2012-10-11
申请号：PCT/US2012020188
申请日：2012-01-04
申请人： UNIV YALE , FORSKARPATENT I UPPSALA AB , LIFTON RICHARD P , ZHAO BIXIAO , AKERSTROEM GOERAN , WESTIN GUNNAR , BJOERKLUND PEYMAN , HELLMAN PER , CHOI MURIM
发明人： LIFTON RICHARD P , ZHAO BIXIAO , AKERSTROEM GOERAN , WESTIN GUNNAR , BJOERKLUND PEYMAN , HELLMAN PER , CHOI MURIM
IPC分类号： C07K14/00 , C07H21/00 , G01N33/48
CPC分类号： C07K14/435 , A61K49/06 , A61K51/00 , C07K14/705 , C12Q1/686 , C12Q1/6883 , C12Q1/6886 , C12Q2600/156 , G01N33/6893
摘要： Provided are KCNJ5 polypeptides and nucleic acids with mutations associated with adrenal diseases and disorders. Further provided are compositions and methods for the assessment, characterization and treatment of adrenal diseases and disorders, based upon the presence or absence of a KCNJ5 mutation that is associated with an adrenal disease or disorder.
摘要翻译：提供的是具有与肾上腺疾病和病症相关的突变的KCNJ5多肽和核酸。还提供了基于与肾上腺疾病或病症相关的KCNJ5突变的存在或不存在来评估，表征和治疗肾上腺疾病和病症的组合物和方法。

2. 发明申请

WO2012094394A9 METHODS AND COMPOSITIONS FOR ASSESSING AND TREATING ADRENAL DISEASES AND DISORDERS 审中-公开
标题翻译：用于评估和治疗肾上腺疾病和病症的方法和组合物
公开(公告)号：WO2012094394A9
公开(公告)日：2012-08-30
申请号：PCT/US2012020188
申请日：2012-01-04
申请人： UNIV YALE , FORSKARPATENT I UPPSALA AB , LIFTON RICHARD P , ZHAO BIXIAO , AKERSTROEM GOERAN , WESTIN GUNNAR , BJOERKLUND PEYMAN , HELLMAN PER , CHOI MURIM
发明人： LIFTON RICHARD P , ZHAO BIXIAO , AKERSTROEM GOERAN , WESTIN GUNNAR , BJOERKLUND PEYMAN , HELLMAN PER , CHOI MURIM
IPC分类号： C07K14/72
CPC分类号： C07K14/435 , A61K49/06 , A61K51/00 , C07K14/705 , C12Q1/686 , C12Q1/6883 , C12Q1/6886 , C12Q2600/156 , G01N33/6893
摘要： The present invention relates to the discovery that mutations in KCNJ5 are associated with adrenal diseases and disorders. The invention includes compositions and methods for the assessment, characterization and treatment of adrenal diseases and disorders, based upon the presence or absence of a KCNJ5 mutation that is associated with an adrenal disease or disorder.
摘要翻译：本发明涉及KCNJ5中的突变与肾上腺疾病和病症相关的发现。本发明包括用于基于与肾上腺疾病或病症相关的KCNJ5突变的存在或不存在来评估，表征和治疗肾上腺疾病和病症的组合物和方法。

3. 发明申请

WO2012094394A2 METHODS AND COMPOSITIONS FOR ASSESSING AND TREATING ADRENAL DISEASES AND DISORDERS 审中-公开
标题翻译：用于评估和治疗ADRENAL疾病和疾病的方法和组合物
公开(公告)号：WO2012094394A2
公开(公告)日：2012-07-12
申请号：PCT/US2012/020188
申请日：2012-01-04
申请人： YALE UNIVERSITY , FORSKARPATENT I UPPSALA AB , LIFTON, Richard, P. , ZHAO, Bixiao , AKERSTRÖM, Göran , WESTIN, Gunnar , BJÖRKLUND, Peyman , HELLMAN, Per , CHOI, Murim
发明人： LIFTON, Richard, P. , ZHAO, Bixiao , AKERSTRÖM, Göran , WESTIN, Gunnar , BJÖRKLUND, Peyman , HELLMAN, Per , CHOI, Murim
IPC分类号： C07K14/72
CPC分类号： C07K14/435 , A61K49/06 , A61K51/00 , C07K14/705 , C12Q1/686 , C12Q1/6883 , C12Q1/6886 , C12Q2600/156 , G01N33/6893
摘要： The present invention relates to the discovery that mutations in KCNJ5 are associated with adrenal diseases and disorders. The invention includes compositions and methods for the assessment, characterization and treatment of adrenal diseases and disorders, based upon the presence or absence of a KCNJ5 mutation that is associated with an adrenal disease or disorder.
摘要翻译：本发明涉及KCNJ5中的突变与肾上腺疾病和病症有关的发现。基于与肾上腺疾病或病症相关的KCNJ5突变的存在或不存在，本发明包括用于评估，表征和治疗肾上腺疾病和病症的组合物和方法。

4. 发明申请

WO1986004360A1 TOOL STEEL 审中-公开
标题翻译：工具钢
公开(公告)号：WO1986004360A1
公开(公告)日：1986-07-31
申请号：PCT/SE1986000010
申请日：1986-01-14
申请人： KLOSTER SPEEDSTEEL AKTIEBOLAG , HELLMAN, Per , WISELL, Henry
发明人： KLOSTER SPEEDSTEEL AKTIEBOLAG
IPC分类号： C22C33/02
CPC分类号： C22C33/0257 , B22F3/24
摘要： A tool steel, comprising high speed steel and cold working steel, produced from metal powder by compaction at a high pressure and a high temperature to full density. The steel is characterized in that a) at least 40% of the carbides of a randomly chosen section have a largest extension > 1.5 mu m, b) at least 25% of the carbide area of a randomly chosen section is contributed by carbides with an extension > 3 mu m, c) the steel contains carbides, the maximum size Lmax of these carbides and/or of carbide aggregates being a function of the diameter or smallest gauge of the product, and that d) the steel contains at least 0.7% carbon and at least 10% of one or several of the following metals: chromium, tungsten, molybdenum, and vanadium, or mixtures of these.
摘要翻译：包括高速钢和冷加工钢的工具钢，由金属粉末通过高压和高温至全密度的压实制成。钢的特征在于a）随机选择的部分的至少40％的碳化物具有>1.5μm的最大延伸，b）随机选择的部分的碳化物面积的至少25％由碳化物与延伸>3μm，c）钢含有碳化物，这些碳化物和/或碳化物聚集体的最大尺寸Lmax是产品的直径或最小规格的函数，d）钢含有至少0.7％碳和至少10％的一种或几种以下金属：铬，钨，钼和钒，或它们的混合物。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式