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2. 发明申请

WO2010052342A2 CHEMICAL MESSENGER SENSOR 审中-公开
标题翻译：化学传感器
公开(公告)号：WO2010052342A2
公开(公告)日：2010-05-14
申请号：PCT/EP2009064942
申请日：2009-11-10
申请人： NAT UNIV IRELAND MAYNOOTH , COLLERAN JOHN , HARLEY CLAIRE , ALCOCK BERNADETTE , BRESLIN CARMEL , FINNERTY NIALL
发明人： COLLERAN JOHN , HARLEY CLAIRE , ALCOCK BERNADETTE , BRESLIN CARMEL , FINNERTY NIALL
IPC分类号： G01N33/487 , G01N33/543
CPC分类号： G01N33/5438 , G01N33/942
摘要： A sensor for the detection of chemical messengers is described herein. In particular, a sensor for the detection of serotonin is reported. Serotonin plays a pivotal role as a neurotransmitter in the modulation of a myriad of physiological responses including anger, aggression, mood, sleep, sexuality, and appetite. An electrode for detecting serotonin comprising a conducting or semi-conducting substrate, and a polymer material on said substrate is disclosed. Said polymer comprises a conducting polymer doped with a cyclodextrin macrocycle. Suitable polymer materials include polypyrroles and polythiophenes, e.g. PEDOT. Suitable cyclodextrin macrocycles include anionic cyclodextrin macrocycles, for example sulfonated ß-cyclodextrins (CDs). Also disclosed is a sensor capable of selectively detecting serotonin in the presence of ascorbic acid, epinephrine, norepinephrine and dopamine.
摘要翻译：本文描述了用于检测化学信使的传感器。特别地，报道了用于检测5-羟色胺的传感器。 5-羟色胺作为神经递质在调节无数生理反应（包括愤怒，侵略，情绪，睡眠，性欲和食欲）方面起关键作用。公开了一种用于检测血清素的电极，其包含导电或半导体衬底，以及在所述衬底上的聚合物材料。所述聚合物包含掺杂有环糊精大环的导电聚合物。合适的聚合物材料包括聚吡咯和聚噻吩。 PEDOT。合适的环糊精大环化合物包括阴离子环糊精大环化合物，例如磺化β-环糊精（CD）。还公开了能够在抗坏血酸，肾上腺素，去甲肾上腺素和多巴胺存在下选择性检测5-羟色胺的传感器。

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