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1. 发明申请

WO2008095955A1 CROSS-LINKABLE POLYIONIC COATINGS FOR CONTACT LENSES 审中-公开
标题翻译：用于接触镜的交联聚合物涂层
公开(公告)号：WO2008095955A1
公开(公告)日：2008-08-14
申请号：PCT/EP2008/051448
申请日：2008-02-06
申请人： NOVARTIS AG , GONZALEZ FERREIRO, Maria , KRÖHE, Lutz , MUELLER, Achim , SCHMID, Katharina , VOIGT, Andreas
发明人： GONZALEZ FERREIRO, Maria , KRÖHE, Lutz , MUELLER, Achim , SCHMID, Katharina , VOIGT, Andreas
IPC分类号： G02B1/04
CPC分类号： G02B1/043 , C08J7/04 , Y10T428/31511
摘要： A method for making a contact lens comprising a core material and a coating thereon, the method comprising the steps of : (a) providing the core material; (b) applying one or more layers of a crosslinkable polycationic material, wherein the polycationic material is a reaction product of : (i) an epoxide of formula (I) wherein X equals bromo, chloro, iodo, or cyano, and R 1 , R 2 , R 3 , R 4 , independently of one another, are selected from the group consisting of hydrogen, linear or branched C 1 C 6 -alkyl, and linear or branched C 1 C 6 -alkyl which is substituted with halogen, and (ii) a polymer having repeating units comprising one or more secondary or tertiary amine group(s); (c) applying one or more layers of a polyanionic material; and (d) cross-linking the layers of polyelectrolytes formed by steps (b) and (c). The contact lenses obtainable by the method of the invention have desirable characteristics regarding adherence to the core material, durability, hydrophilicity, and wettability.
摘要翻译：一种用于制造隐形眼镜的方法，所述隐形眼镜包括芯材料和其上的涂层，所述方法包括以下步骤：（a）提供所述芯材料; （b）施加一层或多层可交联聚阳离子材料，其中聚阳离子材料是以下物质的反应产物：（i）式（I）的环氧化物，其中X等于溴，氯，碘或氰基，R 0 R 1，R 2，R 3，R 4和R 4彼此独立地选自氢直链或支链C 1 -C 6 - 烷基和直链或支链C 1 -C 6 - 烷基，其中C 1 -C 6 - 被卤素取代，和（ii）具有包含一个或多个仲胺或叔胺基团的重复单元的聚合物; （c）施加一层或多层聚阴离子材料; 和（d）交联由步骤（b）和（c）形成的聚电解质层。通过本发明的方法可获得的隐形眼镜具有对于芯材的粘附性，耐久性，亲水性和润湿性方面的期望特性。

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