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1. 发明申请

WO1992017447A1 PHENOXYBENZENE DERIVATIVE 审中-公开
标题翻译：苯氧基衍生物
公开(公告)号：WO1992017447A1
公开(公告)日：1992-10-15
申请号：PCT/JP1992000410
申请日：1992-04-02
申请人： KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA , YAMAMOTO, Kozo , FUSE, Yoshihide , KISHIDA, Hideyuki , YASUHARA, Naoko , MIWA, Toshiaki , KATSUMI, Ikuo , HIDAKA, Takayoshi
发明人： KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA
IPC分类号： C07D207/20
CPC分类号： C07D207/26 , C07D207/08 , C07D207/20 , C07D207/24 , C07D207/36 , C07D405/12
摘要： A phenoxybenzene derivative represented by general formula (I), a pharmacologically acceptable salt thereof, and a cerebral function ameliorant and an antidepressant containing the same as an active ingredient. In formula (I) R1 represents hydrogen, C¿1? to C3 alkyl, -OR?6¿ or halogen; R2 represents hydrogen, nitro or amino; R3 represents hydrogen, C¿1? to C8 alkyl, C3 to C5 cycloalkyl, allyl, vinyl or -(CH2)n?1R7; R4¿ represents hydrogen, C¿1? to C3 alkyl or -(CH2)n?3R25; R5¿ represents hydrogen, C¿1? to C3 alkyl or phenyl; X represents (II) wherein Y represents oxygen or sulfur; symbol ... represents either a single or a double bond; and n is 2 when symbol ... represents a single bond and is 1 when symbol ... represents a double bond.

2. 发明申请

WO1994008947A1 NOVEL AMINO ACID DERIVATIVE 审中-公开
标题翻译：新型氨基酸衍生物
公开(公告)号：WO1994008947A1
公开(公告)日：1994-04-28
申请号：PCT/JP1993001482
申请日：1993-10-15
申请人： ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI , KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA , ISHIZUKA, Masaaki , KAWAZU, Masaji , KATSUMI, Toshiaki , FUSE, Yoshihide , MAEDA, Kenji , TAKEUCHI, Tomio
发明人： ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI , KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA
IPC分类号： C07C233/47
CPC分类号： C07C237/12 , C07C233/47 , C07C235/12 , C07C323/59
摘要： A novel amino acid derivative represented by general formula (I) and a salt thereof have been synthesized and it has been found that they promote the growth and physiological action of the T cells of mammals and have an immunomodulator effect and either an antitumor or a carcinostatic effect, and that they also have the effect of promoting the growth of hematopoietic stem cells wherein Y represents 0 or 1; R represents unsusbstituted C1-C8 alkyl, etc.; R represents hydrogen, C1-C5 alkyl, etc.; R represents hydrogen, C1-C8 alkyl, etc.; R represents hydrogen, C1-C3 alkyl, etc.; and R represents -OR , -NR R , etc.
摘要翻译：已经合成了由通式（I）表示的新型氨基酸衍生物及其盐，已经发现它们促进哺乳动物T细胞的生长和生理作用，并且具有免疫调节剂作用和抗肿瘤剂或制癌剂并且它们还具有促进造血干细胞生长的作用，其中Y代表0或1; R 1表示未取代的C 1 -C 8烷基等; R 2表示氢，C 1 -C 5烷基等; R 3表示氢，C 1 -C 8烷基等; R 4表示氢，C 1 -C 3烷基等; 且R 5表示-OR 42，-NR 43 R 44等

3. 发明申请

WO1995004481A1 PHOSPHATASE INHIBITOR, AND SEASONING AND FOOD WHEREIN SAID INHIBITOR IS UTILIZED 审中-公开
标题翻译：磷酸酯酶抑制剂，以及使用抑制剂的食品和食品
公开(公告)号：WO1995004481A1
公开(公告)日：1995-02-16
申请号：PCT/JP1994001299
申请日：1994-08-05
申请人： KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA , KATSUMI, Ikuo , SAITO, Takahiro , YASUHARA, Naoko , KAWABE, Taizo , FUSE, Yoshihide
发明人： KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA
IPC分类号： A23L03/3472
CPC分类号： A23L3/3472 , A23L27/10
摘要： A phosphatase inhibitor comprising at least one member selected from the group consisting of spices or plants of the families Myristicaceae, Rutaceae, Pedaliaceae, Myrtaceae, Apiaceae, Lamiceae, Theaceae, Liliaceae, Mimosaceae, Solanaceae, Fagaceae, Polygonaceae, and Geraniaceae, and extracts thereof; or a phosphatase inhibitor comprising at least one member selected from the group consisting of spices or plants of nutmeg, mace, xanthoxylum fruit, philodendron bank, citrus unshu peel, sesame, clove, allspice, dill, aniseed, rosemary, savory, laurel, oregano, tea, onion peel, peanut endodermis (seed coat) and shell, Cassia obtusifolia, paprika, Quercus salicina, Rumex japonicus, Fagopyrum esculentum shell and Japanese geranium herb, and extracts thereof. A seasoning comprises the above inhibitor and a 5'-ribonucleotide. The use of the inhibitor or the seasoning enables the prevention of deterioration of food taste and the persistence of food flavor.
摘要翻译：一种磷酸酶抑制剂，其包含选自以下的至少一种成分：肉豆蔻科，芸香科，Pedaliaceae，Myrtaceae，Apiaceae，Lamiceae，Theaceae，Laceaceae，Mimosaceae，Solanaceae，Fagaceae，gon科和Geraniaceae的香料或植物， ; 或包含选自以下的至少一种成分的磷酸酶抑制剂，所述成分选自由肉豆蔻，麦麸，花椒果实，藤蔓银，柑橘糊，芝麻，丁香，五香粉，莳萝，茴香，迷迭香，美味，月桂，牛至的香料或植物，茶叶，洋葱皮，花生内皮（种皮）和壳，桂皮，辣椒粉，枸杞，日本j us，荞麦壳和日本天竺葵草药及其提取物。调味料包含上述抑制剂和5'-核糖核苷酸。使用抑制剂或调味料能够防止食物味道的劣化和食物香味的持久性。

4. 发明申请

WO1994019348A1 BICYCLIC NITROGENOUS COMPOUND 审中-公开
标题翻译：双相硝酸化合物
公开(公告)号：WO1994019348A1
公开(公告)日：1994-09-01
申请号：PCT/JP1994000218
申请日：1994-02-14
申请人： KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA , FUSE, Yoshihide , YAMAMOTO, Kozo , KISHIDA, Hideyuki , MIWA, Toshiaki , HIDAKA, Takayoshi , KATSUMI, Ikuo
发明人： KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA
IPC分类号： C07D453/02
CPC分类号： C07D453/02
摘要： A cerebral function ameliorant containing a bicyclic nitrogenous compound represented by general formula (I) or a physiologically acceptable salt thereof as the active ingredient.
摘要翻译：一种脑功能改善剂，其含有通式（I）所示的双环含氮化合物或其生理学上可接受的盐作为有效成分。

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