专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2017177055A1 CYCLODEXTRIN-BASED POLYMERS FOR THERAPEUTIC DELIVERY 审中-公开
标题翻译：基于环糊精的聚合物用于治疗性递送
公开(公告)号：WO2017177055A1
公开(公告)日：2017-10-12
申请号：PCT/US2017/026430
申请日：2017-04-06
申请人： ZHAO, Liang , CASE, Roy l. , VAN DER POLL, Derek Gregory , HALO, Tiffany , ELIASOF, Scott , METCALF, Chester A., III , JAYARAMAN, Lata , ROHDE, Ellen , PETERS, Christian
发明人： ZHAO, Liang , CASE, Roy l. , VAN DER POLL, Derek Gregory , HALO, Tiffany , ELIASOF, Scott , METCALF, Chester A., III , JAYARAMAN, Lata , ROHDE, Ellen , PETERS, Christian
IPC分类号： A61K47/48 , A61K45/06
CPC分类号： A61K45/06 , A61K31/4745 , A61K31/724 , A61K39/39558 , A61K47/6951 , A61K2039/505 , C07K16/32 , C08B37/0012 , A61K2300/00
摘要： Methods and compositions relating to CDP-therapeutic agent antibody conjugates are described herein.
摘要翻译：本文描述了涉及CDP-治疗剂抗体缀合物的方法和组合物。

2. 发明申请

WO2004065576A2 METHODS AND COMPOSITIONS FOR TREATING UROLOGICAL DISORDERS USING 44390, 54181, 211, 5687, 884, 1405, 636, 4421, 5410, 30905, 2045, 16405, 18560, 2047, 33751, 52872, 14063, 20739, 32544, 43239, 44373, 51164, 53010, 16852, 1587, 2207, 22245, 2387, 52908, 69112, 14990, 18547, 115, 579, 15985, 15625, 760, 18603, 2395, 2554, 867 审中-公开
标题翻译：用于使用44390,54181,211,5687,884,1405,636,4421,5410,30905,2045,16405,18560,2047,33751,52872,14063,20739,32544,43239,443373的治疗尿路疾病的方法和组合物， 51164,53010,16852,1587,2207,22245,2377,52908,69112,14990,18547,115,579,15985,15525,760,18603,2355,2554,867
公开(公告)号：WO2004065576A2
公开(公告)日：2004-08-05
申请号：PCT/US2004000750
申请日：2004-01-14
申请人： MILLENNIUM PHARM INC , KARICHETI VENKATESWARLU , SILOS-SANTIAGO INMACULADA , ELIASOF SCOTT D
发明人： KARICHETI VENKATESWARLU , SILOS-SANTIAGO INMACULADA , ELIASOF SCOTT D
IPC分类号： C07K14/47 , C12N
CPC分类号： C07K14/47
摘要： The present invention relates to methods for the diagnosis and treatment of a urological disorder or urological disorders. Specifically, the present invention identifies the differential expression of 44390, 54181, 211, 5687, 884, 1405, 636, 4421, 5410, 30905, 2045, 16405, 18560, 2047, 33751, 52872, 14063, 20739, 32544, 43239, 44373, 51164, 53010, 16852, 1587, 2207, 22245, 2387, 52908, 69112, 14990, 18547, 115, 579, 15985, 15625, 760, 18603, 2395, 2554, 8675, 32720, 4809, 14303, 16816, 17827, 32620, 577, 619, 1423, 2158, 8263, 15402, 16209, 16386, 21165, 30911, 41897, 1643, 2543, 9626, 13231, 32409, 84260, 2882, 8203, 32678 and 55053 genes in tissues relating to urological disorder, relative to their expression in normal, or non-urological disorder disease states, and/or in response to manipulations relevant to a urological disorder. The present invention describes methods for the diagnostic evaluation and prognosis of various urological diseases, and for the identification of subjects exhibiting a predisposition to such conditions. The invention also provides methods for identifying a compound capable of modulating a urological disorder or urological disorders. The present invention also provides methods for the identification and therapeutic use of compounds as treatments of urological disorders.
摘要翻译：本发明涉及诊断和治疗泌尿系统疾病或泌尿系统疾病的方法。具体地，本发明鉴定了44390,54181,211,5687,884,1405,636,4421,5410,30905,2045,16405,18560,2047,33751,52872,14063,20739,32544,43239的差异表达， 44373,51164,53010,16852,1587,2207,22245,2377,52908,69112,14990,188547,115,59,15985,15525,760,18603,2355,2554,8675,32720,4809,14303,16816,165,145,125,118,129,119,109,109,109,109， 17827,3262,577,619,1423,2188,8263,15402,16209,166386,21165,30911,41897,1643,2534,9626,13231,32409,84260,28282,8203,32678和55053基因在与泌尿系统疾病相对于在正常或非泌尿疾病疾病状态中的表达，和/或响应于与泌尿系统疾病相关的操作。本发明描述了各种泌尿疾病的诊断评估和预后的方法，以及用于鉴定表现出这种病症倾向的受试者。本发明还提供了鉴定能够调节泌尿系统疾病或泌尿系统疾病的化合物的方法。本发明还提供了用于鉴定和治疗性使用化合物作为泌尿系统疾病治疗的方法。

3. 发明申请

WO2013025490A1 COMPOSITIONS AND METHODS FOR TREATMENT OF AUTOIMMUNE AND OTHER DISEASES 审中-公开
标题翻译：用于治疗自身免疫和其他疾病的组合物和方法
公开(公告)号：WO2013025490A1
公开(公告)日：2013-02-21
申请号：PCT/US2012/050308
申请日：2012-08-10
申请人： CERULEAN PHARMA INC. , ELIASOF, Scott
发明人： ELIASOF, Scott
IPC分类号： A01N43/04 , A61K31/70
CPC分类号： A61K47/6951 , A61K31/715 , A61K47/58 , A61K47/59 , A61K47/60 , A61K47/61 , B82Y5/00 , Y02A50/414
摘要： Provided are methods relating to the use of CDP-therapeutic agent conjugates for the treatment of autoimmune disease, inflammatory disease, or cancer. Also provided are CDP-therapeutic agent conjugates, particles comprising CDP-therapeutic agent conjugates, and compositions comprising CDP-therapeutic agent conjugates.
摘要翻译：提供了关于使用CDP治疗剂缀合物治疗自身免疫性疾病，炎性疾病或癌症的方法。还提供了CDP治疗剂缀合物，包含CDP治疗剂缀合物的颗粒和包含CDP治疗剂缀合物的组合物。

4. 发明申请

WO2004071411A2 METHODS AND COMPOSITIONS IN TREATING PAIN AND PAINFUL DISORDERS USING 16386, 15402, 21165, 1423, 636, 12303, 21425, 27410, 38554, 38555, 55063, 57145, 59914, 94921, 16852, 33260, 58573, 30911, 85913, 14303, 16816, 17827 OR 32620 审中-公开
标题翻译：使用16386,15402,21165,1423,636,12303,21425,27410,38554,38555,55063,57145,59914,94921,16852,33260,58573,30911,85913,14303的方法和组合物治疗疼痛和疼痛性疾病， 16816，17827或32620
公开(公告)号：WO2004071411A2
公开(公告)日：2004-08-26
申请号：PCT/US2004/002851
申请日：2004-01-30
申请人： MILLENNIUM PHARMACEUTICALS, INC. , SILOS-SANTIAGO, Immaculada , KARICHETI, Venkateswarlu , ELIASOF, Scott, D.
发明人： SILOS-SANTIAGO, Immaculada , KARICHETI, Venkateswarlu , ELIASOF, Scott, D.
IPC分类号： A61K
CPC分类号： G01N33/6893 , C07K16/286 , G01N2333/68
摘要： The present invention relates to methods for the diagnosis and treatment of pain or painful disorders. Specifically, the present invention identifies the differential expression of 16386, 15402, 21165, 1423, 636, 12303, 21425, 27410, 38554, 38555, 55063, 57145, 59914, 94921, 16852, 33260, 58573, 30911, 85913, 14303, 16816, 17827 and 32620 genes in tissues relating to pain sensation, relative to their expression in normal, or non-painful disease states, and/or in response to manipulations relevant to pain. The present invention describes methods for the diagnostic evaluation and prognosis of various pain disorders, and for the identification of subjects exhibiting a predisposition to such conditions. The invention also provides methods for identifying a compound capable of modulating pain or painful disorders. The present invention also provides methods for the identification and therapeutic use of compounds as treatments of pain and painful disorders.
摘要翻译：本发明涉及诊断和治疗疼痛或疼痛疾病的方法。具体地，本发明鉴定16386,15402,21165,1423,636,12303,21425,27410,38554,38555,55063,57145,59914,94921,16852,33260,58573,30911,85913,14303的差异表达，相对于其在正常或非痛苦疾病状态中的表达，和/或响应于与疼痛有关的操作，在与疼痛感觉相关的组织中的16816,17827和32620基因。本发明描述了各种疼痛障碍的诊断评估和预后的方法，以及用于鉴定表现出这种病症倾向的受试者。本发明还提供了鉴定能够调节疼痛或疼痛障碍的化合物的方法。本发明还提供了用于鉴定和治疗性使用化合物作为疼痛和疼痛障碍的治疗方法。

5. 发明申请

WO2010117668A1 POLYMER-AGENT CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS OF USE 审中-公开
标题翻译：聚合物共混物，颗粒，组合物和相关使用方法
公开(公告)号：WO2010117668A1
公开(公告)日：2010-10-14
申请号：PCT/US2010/028770
申请日：2010-03-26
申请人： CERULEAN PHARMA INC. , ELIASOF, Scott , CRAWFORD, Thomas, C. , GANGEL, Geeti , REITER, Lawrence, Alan , NG, Pei-Sze
发明人： ELIASOF, Scott , CRAWFORD, Thomas, C. , GANGEL, Geeti , REITER, Lawrence, Alan , NG, Pei-Sze
IPC分类号： A61K9/00
CPC分类号： A61K47/48853 , A61B2018/00005 , A61K9/0019 , A61K9/14 , A61K9/19 , A61K9/5123 , A61K9/5138 , A61K9/5146 , A61K9/5153 , A61K9/5192 , A61K31/337 , A61K31/704 , A61K31/7068 , A61K45/06 , A61K47/482 , A61K47/58 , A61K47/59 , A61K47/593 , A61K47/60 , A61K47/6935 , A61K47/6937 , A61K49/00 , A61K49/0089 , A61M5/427 , A61P35/00
摘要： Described herein are polymer-agent conjugates and particles, which can be used, for example, in the treatment of cancer. Also described herein are mixtures, compositions and dosage forms containing the particles, methods of using the particles (e.g., to treat a disorder), kits including the polymer-agent conjugates and particles, methods of making the polymer- agent conjugates and particles, methods of storing the particles and methods of analyzing the particles.
摘要翻译：本文描述的是聚合物 - 试剂缀合物和颗粒，其可以用于例如癌症的治疗。本文还描述了含有颗粒的混合物，组合物和剂型，使用颗粒的方法（例如，治疗病症），包括聚合物 - 试剂缀合物和颗粒的试剂盒，制备聚合物 - 试剂缀合物和颗粒的方法，方法存储颗粒和分析颗粒的方法。

6. 发明申请

WO2010114770A1 POLYMER-AGENT CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS OF USE 审中-公开
标题翻译：聚合物共混物，颗粒，组合物和相关使用方法
公开(公告)号：WO2010114770A1
公开(公告)日：2010-10-07
申请号：PCT/US2010/028831
申请日：2010-03-26
申请人： CERULEAN PHARMA INC. , ELIASOF, Scott , CRAWFORD, Thomas C. , GANGAL, Geeti , REITER, Lawrence Alan , NG, Pei-Sze
发明人： ELIASOF, Scott , CRAWFORD, Thomas C. , GANGAL, Geeti , REITER, Lawrence Alan , NG, Pei-Sze
IPC分类号： A61K31/80
CPC分类号： A61K47/482 , A61K9/14 , A61K9/1647 , A61K9/19 , A61K9/5138 , A61K31/337 , A61K31/675 , A61K31/69 , A61K31/704 , A61K31/765 , A61K31/80 , A61K47/593
摘要： Described herein are polymer-agent conjugates and particles, which can be used, for example, in the treatment of cancer. Also described herein are mixtures, compositions and dosage forms containing the particles, methods of using the particles (e.g., to treat a disorder), kits including the polymer-agent conjugates and particles, methods of making the polymer-agent conjugates and particles, methods of storing the particles and methods of analyzing the particles.
摘要翻译：本文描述的是聚合物 - 试剂缀合物和颗粒，其可以用于例如癌症的治疗。本文还描述了含有颗粒的混合物，组合物和剂型，使用颗粒的方法（例如，治疗病症），包括聚合物 - 试剂缀合物和颗粒的试剂盒，制备聚合物 - 试剂缀合物和颗粒的方法，方法存储颗粒和分析颗粒的方法。

7. 发明申请

WO2012024526A3 CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS 审中-公开
标题翻译：结合物，颗粒，成分及相关方法
公开(公告)号：WO2012024526A3
公开(公告)日：2012-07-05
申请号：PCT/US2011048305
申请日：2011-08-18
申请人： CERULEAN PHARMA INC , ELIASOF SCOTT , FETZER OLIVER S , HWANG JUNGYEON , LIM SOO PATRICK , NG PEI-SZE , SVENSON SONKE , BERGSTROM DONALD E
发明人： ELIASOF SCOTT , FETZER OLIVER S , HWANG JUNGYEON , LIM SOO PATRICK , NG PEI-SZE , SVENSON SONKE , BERGSTROM DONALD E
IPC分类号： C12N15/11 , A61K9/16 , A61K9/50 , A61K48/00
CPC分类号： A61K47/482 , A61K9/14 , A61K31/713 , A61K47/593 , A61K47/60 , A61K47/6921 , C12N15/11 , C12N15/113 , C12N15/115 , C12N15/87 , C12N2310/14 , C12N2310/351 , C12N2320/32 , Y10T428/2982
摘要： Particles and conjugates for delivering nucleic acid agents. Compositions containing the particles, the conjugates, or both. Methods of using the particles, the conjugates, and the compositions.
摘要翻译：用于递送核酸试剂的颗粒和共轭物。含有颗粒，共轭物或两者的组合物。使用颗粒，共轭物和组合物的方法。

8. 发明申请

WO2012050899A1 POLYMER-AGENT CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS OF USE 审中-公开
标题翻译：聚合物共混物，颗粒，组合物和相关使用方法
公开(公告)号：WO2012050899A1
公开(公告)日：2012-04-19
申请号：PCT/US2011/053716
申请日：2011-09-28
申请人： CERULEAN PHARMA INC. , CRAWFORD, Thomas, C. , ELIASOF, Scott , GANGAL, Geeti , NG, Pei-Sze , REITER, Lawrence, Alan , ZHANG, Jerry
发明人： CRAWFORD, Thomas, C. , ELIASOF, Scott , GANGAL, Geeti , NG, Pei-Sze , REITER, Lawrence, Alan , ZHANG, Jerry
IPC分类号： A61K9/14 , A61K31/765
CPC分类号： A61K9/0019 , A61K31/337 , A61K31/505 , A61K31/704 , A61K47/543 , A61K47/593 , A61K47/60
摘要： Described herein are polymer-agent conjugates and particles, which can be used, for example, in the treatment of cancer. Also described herein are mixtures, compositions and dosage forms containing the particles, methods of using the particles (e.g., to treat a disorder), kits including the polymer-agent conjugates and particles, methods of making the polymer-agent conjugates and particles, methods of storing the particles and methods of analyzing the particles.
摘要翻译：本文描述的是聚合物 - 试剂缀合物和颗粒，其可以用于例如癌症的治疗。本文还描述了含有颗粒的混合物，组合物和剂型，使用颗粒的方法（例如，治疗病症），包括聚合物 - 试剂缀合物和颗粒的试剂盒，制备聚合物 - 试剂缀合物和颗粒的方法，方法存储颗粒和分析颗粒的方法。

9. 发明申请

WO2010114768A1 POLYMER-EPOTHILONE CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS OF USE 审中-公开
标题翻译：聚合物 - EPOTHILONE共混物，颗粒，组合物及相关使用方法
公开(公告)号：WO2010114768A1
公开(公告)日：2010-10-07
申请号：PCT/US2010/028793
申请日：2010-03-26
申请人： CERULEAN PHARMA INC. , ELIASOF, Scott , CRAWFORD, Thomas, C. , GANGAL, Geeti , REITER, Lawrence, Alan , NG, Pei-sze
发明人： ELIASOF, Scott , CRAWFORD, Thomas, C. , GANGAL, Geeti , REITER, Lawrence, Alan , NG, Pei-sze
IPC分类号： A61K9/127
CPC分类号： A61K47/48915 , A61K47/59 , A61K47/593 , A61K47/60 , A61K47/6921 , A61K47/6925 , B82Y5/00
摘要： Described herein are polymer-agent conjugates and particles, which can be used, for example, in the treatment of cancer or neurological deficits. Also described herein are mixtures, compositions and dosage forms containing the particles, methods of using the particles (e.g., to treat a disorder), kits including the polymer-agent conjugates and particles, methods of making the polymer- agent conjugates and particles, methods of storing the particles and methods of analyzing the particles.
摘要翻译：本文描述的是聚合物 - 试剂缀合物和颗粒，其可以用于例如治疗癌症或神经缺陷。本文还描述了含有颗粒的混合物，组合物和剂型，使用颗粒的方法（例如，治疗病症），包括聚合物 - 试剂缀合物和颗粒的试剂盒，制备聚合物 - 试剂缀合物和颗粒的方法，方法存储颗粒和分析颗粒的方法。

10. 发明申请

WO2012024526A2 CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS 审中-公开
标题翻译：缀合物，颗粒，组合物和相关方法
公开(公告)号：WO2012024526A2
公开(公告)日：2012-02-23
申请号：PCT/US2011/048305
申请日：2011-08-18
申请人： CERULEAN PHARMA INC. , ELIASOF, Scott , FETZER, Oliver, S. , HWANG, Jungyeon , LIM SOO, Patrick , NG, Pei-sze , SVENSON, Sonke , BERGSTROM, Donald, E.
发明人： ELIASOF, Scott , FETZER, Oliver, S. , HWANG, Jungyeon , LIM SOO, Patrick , NG, Pei-sze , SVENSON, Sonke , BERGSTROM, Donald, E.
IPC分类号： A61K48/00
CPC分类号： A61K47/482 , A61K9/14 , A61K31/713 , A61K47/593 , A61K47/60 , A61K47/6921 , C12N15/11 , C12N15/113 , C12N15/115 , C12N15/87 , C12N2310/14 , C12N2310/351 , C12N2320/32 , Y10T428/2982
摘要： Particles and conjugates for delivering nucleic acid agents. Compositions containing the particles, the conjugates, or both. Methods of using the particles, the conjugates, and the compositions.
摘要翻译：用于递送核酸试剂的颗粒和缀合物。含有颗粒，偶联物或两者的组合物。使用这些颗粒，缀合物和组合物的方法。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式