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1. 发明申请

WO9515001A3 ENHANCED RESOLUTION MALDI TOF-MS SAMPLE SURFACE 审中-公开
标题翻译：增强分解MALDI TOF-MS样品表面
公开(公告)号：WO9515001A3
公开(公告)日：1995-09-21
申请号：PCT/US9412963
申请日：1994-11-09
申请人： WATERS CORP , JARRELL JOSEPH A , TOMANY MICHAEL J , DORSCHEL CRAIG A
发明人： JARRELL JOSEPH A , TOMANY MICHAEL J , DORSCHEL CRAIG A
IPC分类号： G01N1/28 , H01J49/04 , H01J49/16 , H01J
CPC分类号： H01J49/0418 , G01N1/2813
摘要： A thin layer for sample analysis by matrix-assisted laser desorption mass spectrometry, comprising a matrix material in a supported dispersion wherein the support is a solid or is formed from a solid. The invention is also directed to a method of making a thin layer for sample analysis by matrix-assisted laser desorption mass spectrometry, the layer comprising a matrix-solid composition disposed upon a substrate, comprising the step of depositing a solution containing matrix, solid and solvent upon a spinning substrate at a deposition rate sufficient to allow evaporation of the solvent, thereby interspersing the matrix and support on the substrate in a thin layer. Enhanced mass resolution is described.

2. 发明申请

WO2011091023A1 TECHNIQUES FOR EFFICIENT FRAGMENTATION OF PEPTIDES 审中-公开
标题翻译：用于有效分散肽的技术
公开(公告)号：WO2011091023A1
公开(公告)日：2011-07-28
申请号：PCT/US2011/021696
申请日：2011-01-19
申请人： WATERS TECHNOLOGIES CORPORATION , GEROMANOS, Scott, J. , VISSERS, Johannes, P.C. , DORSCHEL, Craig, A. , CHAKRABORTY, Asish, B. , CHEN, Weibin
发明人： GEROMANOS, Scott, J. , VISSERS, Johannes, P.C. , DORSCHEL, Craig, A. , CHAKRABORTY, Asish, B. , CHEN, Weibin
IPC分类号： H01J49/00
CPC分类号： H01J49/0031 , G01N30/7266 , H01J49/005 , H01J49/14
摘要： Techniques are described for performing mass spectrometry. A stream of one or more ions is generated. The stream is transmitted into a collision cell over a period of time. In accordance with a set of criteria including a retention time of one or more precursor ions, a collision energy of the collision cell is selected to generate one or more product ions for said one or more precursor ions in said stream.
摘要翻译：描述了进行质谱分析的技术。产生一个或多个离子流。流在一段时间内被传送到碰撞单元。根据包括一个或多个前体离子的保留时间的一组标准，选择碰撞池的碰撞能量以产生所述流中所述一种或多种前体离子的一种或多种产物离子。

3. 发明申请

WO1995015001A2 ENHANCED RESOLUTION MALDI TOF-MS SAMPLE SURFACE 审中-公开
标题翻译：增强分解MALDI TOF-MS样品表面
公开(公告)号：WO1995015001A2
公开(公告)日：1995-06-01
申请号：PCT/US1994012963
申请日：1994-11-09
申请人： WATERS CORPORATION , JARRELL, Joseph, A. , TOMANY, Michael, J. , DORSCHEL, Craig, A.
发明人： WATERS CORPORATION
IPC分类号： H01J00/00
CPC分类号： H01J49/0418 , G01N1/2813
摘要： A thin layer for sample analysis by matrix-assisted laser desorption mass spectrometry, comprising a matrix material in a supported dispersion wherein the support is a solid or is formed from a solid. The invention is also directed to a method of making a thin layer for sample analysis by matrix-assisted laser desorption mass spectrometry, the layer comprising a matrix-solid composition disposed upon a substrate, comprising the step of depositing a solution containing matrix, solid and solvent upon a spinning substrate at a deposition rate sufficient to allow evaporation of the solvent, thereby interspersing the matrix and support on the substrate in a thin layer. Enhanced mass resolution is described.
摘要翻译：用于通过基质辅助激光解吸质谱进行样品分析的薄层，其包括在支持的分散体中的基质材料，其中载体是固体或由固体形成。本发明还涉及通过基质辅助激光解吸质谱法制备用于样品分析的薄层的方法，所述层包含置于基材上的基质 - 固体组合物，该方法包括以下步骤：沉积含有基质，固体和溶剂在旋转衬底上，以足以允许溶剂蒸发的沉积速率，从而将基体和支撑物分散在薄层上的衬底上。描述了增强的质量分辨率。

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