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    • 1. 发明申请
    • ELECTRONIC NMR REFERENCE SIGNAL SYSTEMS AND METHODS
    • 电子NMR参考信号系统和方法
    • WO2009111756A2
    • 2009-09-11
    • PCT/US2009036421
    • 2009-03-06
    • VARIAN INCMEHR KNUT GUSTAVAVIZONIS DAINA ZOFIJADIXON JOHN MARKJOHN BOBAN KURIAKOSE
    • MEHR KNUT GUSTAVAVIZONIS DAINA ZOFIJADIXON JOHN MARKJOHN BOBAN KURIAKOSE
    • A61B5/055
    • G01R33/583G01R33/36
    • According to some embodiments, a synthetic nuclear magnetic resonance (NMR) reference signal is injected into the receive path of an NMR spectrometer, after the NMR probe and before the receive amplifier. The synthetic signal is generated using a transmit path for the same channel or for a different channel than the reference signal detection channel. The reference signal is coupled from a transmit-path reference signal coupler situated before a transmit amplifier to a receive-path reference signal coupler situated between the probe and the receive amplifier. The reference signal couplers may include passive directional couplers and/or active switches. The synthetic signal samples the receive path of the system but is not substantially affected by intra-probe interactions. Using a well-defined existing NMR channel to generate the reference signal allows superior control of reference signal characteristics, and does not require a dedicated spare channel for the reference signal.
    • 根据一些实施例,在NMR探针之后和接收放大器之前,将合成核磁共振(NMR)参考信号注入到NMR分光计的接收路径中。 合成信号是使用用于相同信道或不同于参考信号检测信道的信道的发送路径生成的。 参考信号从位于发射放大器之前的发射路径参考信号耦合器耦合到位于探测器和接收放大器之间的接收路径参考信号耦合器。 参考信号耦合器可以包括无源定向耦合器和/或有源开关。 合成信号对系统的接收路径进行采样,但基本上不受探头内相互作用的影响。 使用明确定义的现有NMR信道来生成参考信号允许对参考信号特性的出众控制,并且不需要用于参考信号的专用备用信道。