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    • 1. 发明申请
    • BRAZING METHODS FOR PDC CUTTERS
    • PDC切割机的制作方法
    • WO2010088504A1
    • 2010-08-05
    • PCT/US2010/022565
    • 2010-01-29
    • SMITH INTERNATIONAL, INC.ZHANG, YouheSHEN, YuelinDENG, Hong
    • ZHANG, YouheSHEN, YuelinDENG, Hong
    • E21B10/567B23K31/02
    • E21B10/573B23K1/0008B23K35/0222B23K35/0244B23K35/0255B23K35/30B23K35/3006
    • A method for manufacturing a down hole cutting tool, wherein the cutting tool includes a cutting element support structure having at least one cutter pocket formed therein to support a cutting element comprising a substrate and an ultrahard layer, wherein the method includes inserting a base portion of the cutting element into the cutter pocket; locating a first braze alloy such that when heated the first braze alloy melts and fills a space in the cutter pocket between the cutting element and the cutting element support structure adjacent the ultrahard layer; locating a second braze alloy such that when heated the second braze alloy melts and fills a space in the cutter pocket between the cutting element and the cutting element support structure non-adjacent the ultrahard layer; and heating the first and second braze alloy such that they melt.
    • 一种用于制造井下切割工具的方法,其中所述切割工具包括切割元件支撑结构,所述切割元件支撑结构具有形成在其中的至少一个切割器凹坑,以支撑包括基底和超硬层的切割元件,其中所述方法包括: 切割元件进入刀口袋; 定位第一钎焊合金,使得当加热时,第一钎焊合金熔化并填充切割元件和与超硬层相邻的切割元件支撑结构之间的刀具槽中的空间; 定位第二钎焊合金,使得当被加热时,第二钎焊合金熔化并填充切割元件和不邻近超硬层的切割元件支撑结构之间的刀具槽中的空间; 并加热第一和第二钎焊合金使其熔化。
    • 3. 发明申请
    • METHODS FOR DETECTING GENES ASSOCIATED WITH BONE PROPERTIES AND/OR HEIGHT
    • 检测与骨性质和/或高度相关的基因的方法
    • WO2004018642A2
    • 2004-03-04
    • PCT/US0326657
    • 2003-08-25
    • UNIV CREIGHTONRECKER ROBERT RDENG HONG-WEN
    • RECKER ROBERT RDENG HONG-WEN
    • C12Q1/68C12N
    • C12Q1/6883C12Q2600/156
    • Disclosed are methods for detecting the presence in a subject of a polymorphism linked to a gene associated with one or more bone properties, such as spine bone size, hip bone size, and wrist bone size. The method includes analyzing at least a portion of the subject's genome and detecting the presence of a polymorphism which is located in or near various specified regions of the subject's genome and which is linked to the gene associated with the bone property of interest. The presence of the polymorphism is indicative of the subject having or being susceptible to having aberrant bone properties. Also disclosed are methods for detecting the presence in a subject of a polymorphism linked to a gene associated with height. The methods can be used, for example, to screen for a subject's having or being susceptible to conditions such as osteoporosis and conditions associated with aberrant height.
    • 公开了用于检测与一种或多种骨性质(例如脊骨尺寸,髋骨大小和腕骨尺寸)相关的基因连接的多态性的受试者中存在的方法。 该方法包括分析受试者的基因组的至少一部分并检测多态性的存在,所述多态性位于受试者的基因组的各个指定区域内或附近,并且与与感兴趣的骨性质相关的基因连接。 多态性的存在表明受试者具有或易于具有异常骨性质。 还公开了用于检测与高度相关的基因连锁的多态性的受试者中存在的方法。 例如,可以使用这些方法来筛选具有或易受诸如骨质疏松症和与异常高度相关的病症的受试者的影响。