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    • 1. 发明申请
    • BUFFALO MILK GANGLIOSIDES
    • WO2003055497A1
    • 2003-07-10
    • PCT/EP2002/014876
    • 2002-12-20
    • SOCIETE DES PRODUITS NESTLE S.A.BERGER, AlvinTURINI, MarcoCOLAROW, Ladislas
    • BERGER, AlvinTURINI, MarcoCOLAROW, Ladislas
    • A61K31/7032
    • C07H15/10A23C11/04A23C21/04A23L33/40
    • The present invention relates to gangliosides derived or isolated from buffalo milk, skimmed buffalo milk, buffalo milk serum or derivatives of either. Buffalo milk is reported to comprise gangliosides that are not contained in bovine milk, such as gangliosides that belong to the GM1-class. Furthermore, buffalo milk is found to comprise unknown gangliosides, denoted herein as ganglioside "F" and "L". Furthermore, the invention reports that gangliosides are surprisingly found in fractions of isolation procedures that were so far not considered to comprise gangliosides. Finally, milk or milk serum from buffalo, for example as derived from mozzarella cheese production, contains specific gangliosides in the same amounts as human breast milk, which makes it suitable for humanisation of infant and other formulas.
    • 本发明涉及从水牛奶,脱脂水牛奶,水牛奶血清或其衍生物衍生或分离的神经节苷脂。 据报道,水牛奶包含不包含在牛奶中的神经节苷脂,例如属于GM1类的神经节苷脂。 此外,水牛奶被发现包含未知的神经节苷脂,本文称为神经节苷脂“F”和“L”。 此外,本发明报道说,神经节苷脂在迄今为止未被认为包含神经节苷脂的分离程序的部分中令人惊奇地发现。 最后,来自水牛的牛奶或牛奶血清,例如来源于莫扎里拉奶酪生产,含有与人母乳相同量的特定神经节苷脂,使其适合于婴儿和其他配方的人源化。