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1. 发明申请

WO2011069010A3 AMANTADINE COMPOSITIONS AND METHODS OF USE 审中-公开
标题翻译：氨基甲酸酯组合物和使用方法
公开(公告)号：WO2011069010A3
公开(公告)日：2011-07-28
申请号：PCT/US2010058789
申请日：2010-12-02
申请人： ADAMAS PHARMACEUTICALS INC , WENT GREG , SATHYAN GAYATRI , KATDARE ASHOK , VERMANI KAVITA , GANAPATI GANGADHARA , COFFEE MICHAEL , SHEK EFRAIM
发明人： WENT GREG , SATHYAN GAYATRI , KATDARE ASHOK , VERMANI KAVITA , GANAPATI GANGADHARA , COFFEE MICHAEL , SHEK EFRAIM
IPC分类号： A01N33/02 , A61K31/13
CPC分类号： A61K31/13 , A61K9/0002 , A61K9/0004 , A61K9/0053 , A61K9/14 , A61K9/48 , A61K9/4808 , A61K9/4891 , A61K9/50 , A61K9/5015 , A61K9/5026 , A61K9/5047 , A61K9/5078 , A61K31/198
摘要： Methods of nighttime administration of amantadine to reduce sleep disturbances in patient undergoing treatment with amantadine are described, as well as compositions of extended release amantadine that are suitable for nighttime administration.
摘要翻译：描述了夜间施用金刚烷胺以减少用金刚烷胺治疗的患者的睡眠障碍的方法，以及适用于夜间给药的延长释放金刚烷胺的组合物。

2. 发明申请

WO2011069010A2 AMANTADINE COMPOSITIONS AND METHODS OF USE 审中-公开
标题翻译：麝香菊苷组合物和使用方法
公开(公告)号：WO2011069010A2
公开(公告)日：2011-06-09
申请号：PCT/US2010/058789
申请日：2010-12-02
申请人： ADAMAS PHARMACEUTICALS, INC. , WENT, Greg , SATHYAN, Gayatri , KATDARE, Ashok , VERMANI, Kavita , GANAPATI, Gangadhara , COFFEE, Michael , SHEK, Efraim
发明人： WENT, Greg , SATHYAN, Gayatri , KATDARE, Ashok , VERMANI, Kavita , GANAPATI, Gangadhara , COFFEE, Michael , SHEK, Efraim
IPC分类号： A61K31/13
CPC分类号： A61K31/13 , A61K9/0002 , A61K9/0004 , A61K9/0053 , A61K9/14 , A61K9/48 , A61K9/4808 , A61K9/4891 , A61K9/50 , A61K9/5015 , A61K9/5026 , A61K9/5047 , A61K9/5078 , A61K31/198
摘要： Methods of nighttime administration of amantadine to reduce sleep disturbances in patient undergoing treatment with amantadine are described, as well as compositions of extended release amantadine that are suitable for nighttime administration.
摘要翻译：描述了夜间施用金刚烷胺以减少经历用金刚烷胺治疗的患者的睡眠障碍的方法，以及适用于夜间施用的延长释放金刚烷胺的组合物。

3. 发明申请

WO2007127934A3 BINARY DATA RELAY SYSTEMS AND METHODS FOR REAL-TIME COMMUNICATION OF BINARY DATA THROUGH A PEER-TO- PEER NETWORK 审中-公开
公开(公告)号：WO2007127934A3
公开(公告)日：2007-11-08
申请号：PCT/US2007/067658
申请日：2007-04-27
申请人： NETGEN COMMUNICATIONS, INC. , COFFEE, Michael, B. , SCHORNAK, Clifford, J.
发明人： COFFEE, Michael, B. , SCHORNAK, Clifford, J.
IPC分类号： H04L12/28 , H04L12/56 , H04L5/12 , H04M11/00 , H04N1/00 , H04N1/04 , H04N7/14
摘要： Binary data relay systems and methods are disclosed to allow users of peer-to- peer (P2P) communications networks designed for voice transport to send facsimile (fax) messages between P2P endpoints by using a computer (102, 104) suitably connected to the network (164). Although not limited to this implementation, this connection preferably uses the Internet to effect the connection between endpoint computers (102, 104). The computer (102, 104) may also be suitably connected to a facsimile terminal (160, 162). The binary data relay systems and methods provide the facsimile communications function, such as that usually provided by a stand-alone Group 3 facsimile terminal (160, 162), over the P2P network (164) intended for voice transmission, such as but not limited to, the Skype network. Such P2P network (164) is an overlay of the Internet, but is not limited to the Internet.

4. 发明申请

WO2007067582A3 PROCESS FOR MANUFACTURING CHEWABLE DOSAGE FORMS FOR DRUG DELIVERY AND PRODUCTS THEREOF 审中-公开
标题翻译：制造用于药物输送及其制品的CHEWABLE剂型的方法
公开(公告)号：WO2007067582A3
公开(公告)日：2007-08-02
申请号：PCT/US2006046470
申请日：2006-12-05
申请人： TRIAD SPECIALTY PRODUCTS LLC , PAULSEN NEIL E , JOHNSON ROLAND , COFFEE MICHAEL
发明人： PAULSEN NEIL E , JOHNSON ROLAND , COFFEE MICHAEL
IPC分类号： A61K47/00
CPC分类号： A61K9/0056 , A61K9/1617 , A61K9/1623 , A61K9/1641 , A61K9/1652 , A61K9/1664 , A61K9/2013 , A61K9/2018 , A61K9/2031 , A61K9/2059 , A61K9/2068 , A61K9/2077 , A61K9/2081 , A61K9/2095 , A61K9/5047 , A61K47/06 , A61K47/10 , A61K47/26 , A61K47/36 , A61K47/44 , A61K47/46
摘要： A palatable, soft chewable medication vehicle for delivery of a pharmaceutically acceptable active ingredient, such as a drug, to an animal or human subject. The soft chews contain only food grade or better inactive ingredients, and preferably do not contain ingredients of animal origin. Processes for manufacturing the soft chews do not require the generation of heat during mixing of active and inactive ingredients, provide stable concentrations of the active ingredient, and produce chews of consistent weight and texture.
摘要翻译：一种用于将药学上可接受的活性成分（例如药物）递送到动物或人类受试者的可口的，软的咀嚼药物载体。软咀嚼物仅含有食品级或更好的非活性成分，并且优选不含动物来源的成分。用于制造软咀嚼物的方法不需要在混合活性成分和非活性成分期间产生热量，提供稳定浓度的活性成分，并产生一致的重量和质地的咀嚼物。

5. 发明申请

WO2007127934A2 BINARY DATA RELAY SYSTEMS AND METHODS FOR REAL-TIME COMMUNICATION OF BINARY DATA THROUGH A PEER-TO- PEER NETWORK 审中-公开
标题翻译：二进制数据继电器系统和通过对等网络实时通信二进制数据的方法
公开(公告)号：WO2007127934A2
公开(公告)日：2007-11-08
申请号：PCT/US2007067658
申请日：2007-04-27
申请人： NETGEN COMMUNICATIONS INC , COFFEE MICHAEL B , SCHORNAK CLIFFORD J
发明人： COFFEE MICHAEL B , SCHORNAK CLIFFORD J
IPC分类号： H04L12/28
CPC分类号： H04L29/06027 , H04L65/1069 , H04N1/00214 , H04N1/00217
摘要： Binary data relay systems and methods are disclosed to allow users of peer-to- peer (P2P) communications networks designed for voice transport to send facsimile (fax) messages between P2P endpoints by using a computer (102, 104) suitably connected to the network (164). Although not limited to this implementation, this connection preferably uses the Internet to effect the connection between endpoint computers (102, 104). The computer (102, 104) may also be suitably connected to a facsimile terminal (160, 162). The binary data relay systems and methods provide the facsimile communications function, such as that usually provided by a stand-alone Group 3 facsimile terminal (160, 162), over the P2P network (164) intended for voice transmission, such as but not limited to, the Skype network. Such P2P network (164) is an overlay of the Internet, but is not limited to the Internet.
摘要翻译：公开了二进制数据中继系统和方法，以允许设计用于语音传输的对等（P2P）通信网络的用户通过使用适于连接到网络的计算机（102,104）在P2P端点之间发送传真（传真）消息（164）。尽管不限于该实现，但是该连接优选地使用因特网来实现端点计算机（102,104）之间的连接。计算机（102,104）也可以适当地连接到传真终端（160,162）。二进制数据中继系统和方法提供传真通信功能，例如通常由独立的组3传真终端（160,162）提供的传真通信功能，通过用于语音传输的P2P网络（164），例如但不限于到，Skype网络。这样的P2P网络（164）是互联网的覆盖，但不限于因特网。

6. 发明申请

WO2009064859A1 PROCESS FOR MANUFACTURING CHEWABLE DOSAGE FORMS FOR DRUG DELIVERY AND PRODUCTS THEREOF 审中-公开
标题翻译：制造用于药物输送及其制品的CHEWABLE剂型的方法
公开(公告)号：WO2009064859A1
公开(公告)日：2009-05-22
申请号：PCT/US2008/083373
申请日：2008-11-13
申请人： PIEDMONT PHARMACEUTICALS LLC , PAULSEN, Neil, E. , JOHNSON, Roland , COFFEE, Michael
发明人： PAULSEN, Neil, E. , JOHNSON, Roland , COFFEE, Michael
IPC分类号： A61K9/60
CPC分类号： A61K9/0056 , A61K9/0087 , A61K31/7048 , A61K47/10 , A61K47/36 , A61K47/38 , A61K47/44
摘要： A palatable, edible soft chewable medication vehicle for delivery of a pharmaceutically acceptable active ingredient, such as a drug, to an animal or human subject. The edible soft chews contain only food grade or better inactive ingredients, and preferably do not contain ingredients of animal origin. Processes for manufacturing the edible soft chews do not require the use of heat or the addition of water during mixing of active and inactive ingredients, provide stable concentrations of the active ingredient, and produce chews of consistent weight and texture.
摘要翻译：用于将药学上可接受的活性成分（例如药物）递送到动物或人类受试者的可口的可食用软咀嚼药物载体。可食用的软咀嚼物仅含有食品级或更好的非活性成分，优选不含动物来源的成分。用于制造可食用软咀嚼物的方法不需要在混合活性成分和非活性成分期间使用热量或加入水，提供稳定浓度的活性成分，并且产生一致的重量和质地的咀嚼物。

7. 发明申请

WO2007067582A2 PROCESS FOR MANUFACTURING CHEWABLE DOSAGE FORMS FOR DRUG DELIVERY AND PRODUCTS THEREOF 审中-公开
标题翻译：用于制造用于药物递送和其产品的咀嚼剂形式的方法
公开(公告)号：WO2007067582A2
公开(公告)日：2007-06-14
申请号：PCT/US2006/046470
申请日：2006-12-05
申请人： TRIAD SPECIALTY PRODUCTS, LLC , PAULSEN, Neil, E. , JOHNSON, Roland , COFFEE, Michael
发明人： PAULSEN, Neil, E. , JOHNSON, Roland , COFFEE, Michael
IPC分类号： A61K47/00
CPC分类号： A61K9/0056 , A61K9/1617 , A61K9/1623 , A61K9/1641 , A61K9/1652 , A61K9/1664 , A61K9/2013 , A61K9/2018 , A61K9/2031 , A61K9/2059 , A61K9/2068 , A61K9/2077 , A61K9/2081 , A61K9/2095 , A61K9/5047 , A61K47/06 , A61K47/10 , A61K47/26 , A61K47/36 , A61K47/44 , A61K47/46
摘要： A palatable, soft chewable medication vehicle for delivery of a pharmaceutically acceptable active ingredient, such as a drug, to an animal or human subject. The soft chews contain only food grade or better inactive ingredients, and preferably do not contain ingredients of animal origin. Processes for manufacturing the soft chews do not require the generation of heat during mixing of active and inactive ingredients, provide stable concentrations of the active ingredient, and produce chews of consistent weight and texture.
摘要翻译：用于将药学上可接受的活性成分例如药物递送至动物或人类受试者的可口的软软咀嚼药物载体。软咀嚼物只含有食品级或更好的非活性成分，并且最好不含动物来源的成分。用于制造软咀嚼物的方法在混合活性成分和非活性成分期间不需要产生热量，提供稳定浓度的活性成分并产生具有一致重量和质地的咀嚼物。

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