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1. 发明申请

WO2012166921A1 AUTOMATED AND COORDINATED SIMULATION OF MULTIPLE CONCURRENT USER INTERACTIONS 审中-公开
标题翻译：多个并发用户交互的自动和协调仿真
公开(公告)号：WO2012166921A1
公开(公告)日：2012-12-06
申请号：PCT/US2012/040213
申请日：2012-05-31
申请人： THALES AVIONICS, INC. , OLIVEIRA, Edouard , CLOSE, David H. , YI, Jason Kyong-Min , GUNTI, Raghunath Narasimha Murthy , FRANCIOSI, David
发明人： OLIVEIRA, Edouard , CLOSE, David H. , YI, Jason Kyong-Min , GUNTI, Raghunath Narasimha Murthy , FRANCIOSI, David
IPC分类号： G06F9/45
CPC分类号： H04L43/50 , H04L41/082
摘要： A method and associated system are provided for testing components of a vehicle entertainment system, comprising: interconnecting, via a network, a server computer comprising media content, and a plurality of user computers comprising software and hardware via which the user can interact with the media content; loading a test agent component onto a first of the user computers; loading a first scenario file comprising a series of user entry events that emulate user entry actions via a user interface device of the first user computer; executing the user entry events of the first scenario file by the test agent to generate system events that would normally be generated by a user operating the first user computer to interact with media server; and responding to the first user computer, by the server computer, to the system events.
摘要翻译：提供了一种用于测试车辆娱乐系统的组件的方法和相关联的系统，包括：经由网络互连包括媒体内容的服务器计算机以及包括软件和硬件的多个用户计算机，用户可以通过该软件和硬件与媒体进行交互内容; 将测试代理组件加载到第一用户计算机上; 加载包括通过第一用户计算机的用户界面设备模拟用户输入动作的一系列用户输入事件的第一场景文件; 由所述测试代理执行所述第一脚本文件的用户输入事件以生成通常由操作所述第一用户计算机的用户生成的与媒体服务器交互的系统事件; 并且由服务器计算机响应于第一用户计算机到系统事件。

2. 发明申请

WO2011084939A2 PRESSURE RELEASE ENCODING SYSTEM FOR COMMUNICATING DOWNHOLE INFORMATION THROUGH A WELLBORE TO A SURFACE LOCATION 审中-公开
标题翻译：压力释放编码系统，用于通过井眼将表面信息通信到表面位置
公开(公告)号：WO2011084939A2
公开(公告)日：2011-07-14
申请号：PCT/US2011/020084
申请日：2011-01-04
申请人： CLOSE, David , WELLTRONICS APPLICATIONS LLC
发明人： CLOSE, David
IPC分类号： E21B47/12 , G01V1/40
CPC分类号： E21B47/18 , G01V11/00
摘要： A pressure release encoding system (1 ) for communicating downhole information through a wellbore (2) to a surface location (20) include a downhole tool (8) with a valve (36) for providing a fluid restriction to fluid passing in the wellbore (2), a sensor (404) positioned in the wellbore for sensing a downhole condition in the wellbore, a brake (44) cooperative with the valve (36) for moving the valve between at least two positions in timed relation to the downhole condition sensed by the sensor, and a detector (18) positioned at the surface location for providing a measurement value at the surface location correlative to the time between the changes of the pressure of the fluid in the wellbore. The system (1 ) associates position of the valve with pressure transduction. The sensor (404) is an inclination sensor for sensing an angle of inclination of the wellbore.
摘要翻译：用于将井下信息通过井眼（2）传送到表面位置（20）的压力释放编码系统（1）包括具有阀（36）的井下工具（8），用于向在井眼中流动的流体提供流体限制（定位在井眼中的传感器（404），用于感测井眼中的井下状况;与阀（36）协作的制动器（44），用于在至少两个位置之间移动阀门，所述至少两个位置与感测到的井下状况以及位于表面位置处的检测器（18），用于在与井筒内的流体的压力变化之间相关的表面位置提供测量值。系统（1）将阀的位置与压力传导相关联。传感器（404）是用于感测井筒的倾斜角度的倾斜传感器。

3. 发明申请

WO2009040268A1 FIXED SINGLE INJECTION DOSAGE FOR OCRELIZUMAB (2H7) 审中-公开
标题翻译： OCRELIZUMAB固定单次注射用量（2H7）
公开(公告)号：WO2009040268A1
公开(公告)日：2009-04-02
申请号：PCT/EP2008/062286
申请日：2008-09-16
申请人： F. HOFFMANN-LA ROCHE AG , CLOSE, David Robert
发明人： CLOSE, David Robert
IPC分类号： C07K16/28 , A61K39/395 , A61P19/02
CPC分类号： C07K16/2887 , A61K2039/505 , A61K2039/545 , C07K2317/24 , C07K2317/73 , C07K2317/732 , Y02A50/386 , Y02A50/41 , Y02A50/412
摘要： The invention relates to a use of a CD20 antagonist in the manufacture of a medicament for treatment of an autoimmune disease, wherein the medicament is for administration to a human patient in a single therapeutically effective intravenous (i.v.) infusion of said antagonist. The CD20 antagonist preferably is a CD20 antibody, and the autoimmune disease preferably is rheumatoid arthritis.
摘要翻译：本发明涉及CD20拮抗剂在制备用于治疗自身免疫疾病的药物中的用途，其中所述药物用于以单次治疗有效的静脉内（静脉内）输注所述拮抗剂给予人类患者。 CD20拮抗剂优选为CD20抗体，自身免疫性疾病优选为类风湿性关节炎。

4. 发明申请

WO2008014039A3 SYSTEM FOR COMMUNICATING DOWNHOLE INFORMATION THROUGH A WELLBORE TO A SURFACE LOCATION 审中-公开
标题翻译：通过井眼将井下信息通信到地面位置的系统
公开(公告)号：WO2008014039A3
公开(公告)日：2008-10-23
申请号：PCT/US2007068715
申请日：2007-05-10
申请人： CLOSE DAVID
发明人： CLOSE DAVID
IPC分类号： E21B47/16 , E21B47/18 , G01V3/00
CPC分类号： G01V11/00 , E21B47/18
摘要： A pressure release encoding system, as shown in Figure 13, for communicating downhole information through a wellbore to a surface location has a valve (7) for providing a fluid restriction to fluid passing in the wellbore, an inclination sensor (404) postioned in the wellbore for sensing a downhole condition in the welbore, an actuator (400) cooperative with the valve for moving the valve between at least two positions in timed relation to the downhole condition sensed by die sensor (18), and a detector postioned at the surface location for providing a measurement value at the surface location correlative to the time between the changes of the pressure of the fluid in the wellbore.
摘要翻译：如图13所示的用于将井下信息通过井眼传递到表面位置的压力释放编码系统具有阀（7），用于为在井筒中通过的流体提供流体限制;倾斜传感器（404），其位于用于感测井眼中的井下状况的井筒;与阀相配合的致动器（400），用于在至少两个位置之间移动阀门，该至少两个位置与由模具传感器（18）感测的井下状态成正比关系;以及检测器，用于在与井筒中的流体的压力变化之间的时间相关的表面位置处提供测量值的位置。

5. 发明申请

WO2011084939A3 PRESSURE RELEASE ENCODING SYSTEM FOR COMMUNICATING DOWNHOLE INFORMATION THROUGH A WELLBORE TO A SURFACE LOCATION 审中-公开
标题翻译：通过井眼向地表位置传递井下信息的压力释放编码系统
公开(公告)号：WO2011084939A3
公开(公告)日：2011-09-29
申请号：PCT/US2011020084
申请日：2011-01-04
申请人： CLOSE DAVID , WELLTRONICS APPLIC LLC
发明人： CLOSE DAVID
IPC分类号： E21B47/12 , G01V1/40
CPC分类号： E21B47/18 , G01V11/00
摘要： A pressure release encoding system (1 ) for communicating downhole information through a wellbore (2) to a surface location (20) include a downhole tool (8) with a valve (36) for providing a fluid restriction to fluid passing in the wellbore (2), a sensor (404) positioned in the wellbore for sensing a downhole condition in the wellbore, a brake (44) cooperative with the valve (36) for moving the valve between at least two positions in timed relation to the downhole condition sensed by the sensor, and a detector (18) positioned at the surface location for providing a measurement value at the surface location correlative to the time between the changes of the pressure of the fluid in the wellbore. The system (1 ) associates position of the valve with pressure transduction. The sensor (404) is an inclination sensor for sensing an angle of inclination of the wellbore.
摘要翻译：用于将井下信息通过井眼（2）传送到地面位置（20）的压力释放编码系统（1）包括具有阀（36）的井下工具（8），所述阀用于对流过井眼的流体提供流体限制位于井筒中用于感测井眼中的井下条件的传感器（404），与阀门（36）配合用于在至少两个位置之间移动阀门的制动器（44），所述位置与感测到的井下条件通过传感器和位于表面位置的检测器（18），用于在表面位置处提供与井眼中的流体的压力变化之间的时间相关的测量值。系统（1）将阀的位置与压力转换联系起来。传感器（404）是用于感测井筒的倾斜角度的倾斜传感器。

6. 发明申请

WO2017214416A1 METHOD FOR DETERMINING POSITION WITH IMPROVED CALIBRATION BY OPPOSING SENSORS 审中-公开
标题翻译：用反射传感器改进校准确定位置的方法
公开(公告)号：WO2017214416A1
公开(公告)日：2017-12-14
申请号：PCT/US2017/036581
申请日：2017-06-08
申请人： NORALIS LIMITED , CLOSE, David , TROY, George, W.
发明人： CLOSE, David , TROY, George, W.
IPC分类号： E21B47/024 , G01V13/00 , E21B47/26
摘要： The method and system for determining position with improved calibration allows a device to initiate activity at the proper location, such as navigating a drill bit through a rock formation. A pair of position sensors (30, 30') in opposite orientations generates position data signals. A temperature sensor (40) detects temperature and duration of the temperature. An adjusted plastic bias value is determined by a processor module (50) based on the temperature data signal, the duration of the temperature, and the position data signals so as to account for bias and hysteresis errors and error correction based on the opposing orientations of the pair of position sensors. A position value is set according to the adjusted plastic bias value so that the position value is more accurate. The activity of the terminal device (20) is initiated or maintained according to the position value calibrated by the adjusted plastic bias value.
摘要翻译：用于通过改进的校准来确定位置的方法和系统允许装置在适当的位置开始活动，例如在岩层中导航钻头。位置相反的一对位置传感器（30,30'）产生位置数据信号。温度传感器（40）检测温度和温度的持续时间。通过处理器模块（50）基于温度数据信号，温度持续时间和位置数据信号来确定调整的塑料偏置值，以便基于反向偏置和滞后误差以及基于一对位置传感器。位置值根据调整后的塑料偏置值进行设置，以使位置值更准确。终端设备（20）的活动根据由调整的塑料偏差值校准的位置值来启动或维持。

7. 发明申请

WO2017214412A1 METHOD FOR DETERMINING POSITION WITH IMPROVED CALIBRATION 审中-公开
标题翻译：用改进的校准确定位置的方法
公开(公告)号：WO2017214412A1
公开(公告)日：2017-12-14
申请号：PCT/US2017/036577
申请日：2017-06-08
申请人： NORALIS LIMITED , CLOSE, David , TROY, George, W.
发明人： CLOSE, David , TROY, George, W.
IPC分类号： G01D18/00 , E21B47/09
摘要： The method and system for determining position with improved calibration allows a device to initiate activity at the proper location, such as navigating a drill bit through a rock formation. A position sensor (30) having an oscillation element with a range of displacement in a set direction according to gravity generates a position data signal based on an amount of displacement in the set direction. A temperature sensor (40) detects temperature and duration of the temperature. A plastic bias value is determined by a processor module (50) based on the temperature data signal, the duration of the temperature, and the position data signal so as to account for bias and hysteresis errors. A position value is set according to the plastic bias value so that the position value is more accurate. The activity of the terminal device is initiated or maintained according to the position value calibrated by the plastic bias value.
摘要翻译：用于通过改进的校准来确定位置的方法和系统允许装置在适当的位置开始活动，例如在岩层中导航钻头。具有振动元件的位置传感器（30）根据重力在设定方向上具有一定的位移范围，基于设定方向上的位移量生成位置数据信号。温度传感器（40）检测温度和温度的持续时间。处理器模块（50）基于温度数据信号，温度持续时间和位置数据信号来确定塑料偏置值，以便考虑偏置和滞后误差。根据塑料偏置值设置位置值，以使位置值更精确。根据由塑料偏差值校准的位置值启动或维护终端设备的活动。

8. 发明申请

WO2008014039A2 SYSTEM FOR COMMUNICATING DOWNHOLE INFORMATION THROUGH A WELLBORE TO A SURFACE LOCATION 审中-公开
标题翻译：通过井眼将井下信息通信到地面位置的系统
公开(公告)号：WO2008014039A2
公开(公告)日：2008-01-31
申请号：PCT/US2007/068715
申请日：2007-05-10
申请人： CLOSE, David
发明人： CLOSE, David
IPC分类号： E21B47/12 , G01V3/00
CPC分类号： G01V11/00 , E21B47/18
摘要： A pressure release encoding system for communicating downhole information through a wellbore to a surface location has a valve for providing a fluid restriction to fluid passing in the wellbore, a sensor positioned in the wellbore for sensing a downhole condition in the wellbore, an actuator cooperative with the valve for moving the valve between at least two positions in timed relation to the downhole condition sensed by the sensor, and a detector positioned at the surface location for providing a measurement value at the surface location correlative to the time between the changes of the pressure of the fluid in the wellbore. The sensor is an inclination sensor for sensing an angle of inclination of a drill bit in the wellbore.
摘要翻译：用于将井下信息通过井筒传送到表面位置的压力释放编码系统具有阀，用于为在井眼中流动的流体提供流体限制;定位在井眼中的传感器，用于感测井眼中的井下状况;致动器与所述阀用于在至少两个位置之间移动阀，所述至少两个位置与由所述传感器感测的所述井下状态定时关联，以及位于所述表面位置处的检测器，用于在所述表面位置处提供与所述压力变化之间的时间相关的测量值的井眼中的液体。传感器是用于感测钻孔中钻头的倾斜角度的倾角传感器。

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