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1. 发明申请

WO2006128142A3 INHIBITORS OF CYTOSOLIC PHOSPHOLIPASE A2 审中-公开
标题翻译： CYPOSOLIC磷脂酶A2抑制剂
公开(公告)号：WO2006128142A3
公开(公告)日：2007-03-29
申请号：PCT/US2006020847
申请日：2006-05-26
申请人： WYETH CORP , MCKEW JOHN C , LEE KATHERINE L , CHEN LILHREN , VARGAS RICHARD , CLARK JAMES D , WILLIAMS CARA , CLERIN VALERIE , MARUSIC SUZANA , PONG KEVIN
发明人： MCKEW JOHN C , LEE KATHERINE L , CHEN LILHREN , VARGAS RICHARD , CLARK JAMES D , WILLIAMS CARA , CLERIN VALERIE , MARUSIC SUZANA , PONG KEVIN
IPC分类号： C07D209/14 , A61K31/404 , A61P11/00 , A61P19/00 , A61P25/00
CPC分类号： C07D209/14 , C07D209/18
摘要： This invention provides chemical inhibitors of the activity of various phospholipase enzymes, particularly cytosolic phospholipase A 2 enzymes (cPLA 2 ), more particularly including inhibitors of cytosolic phospholipase A2 alpha enzymes (cPLAa). In some embodiments, the inhibitors have the Formula I: wherein the constituent variables are as defined herein.
摘要翻译：本发明提供了各种磷脂酶，特别是细胞溶质磷脂酶A 2 N 2酶（cPLA 2）的活性的化学抑制剂，更具体地包括胞浆磷脂酶A2α酶抑制剂（cPLAa ）。在一些实施方案中，抑制剂具有式I：其中组成变量如本文所定义。

2. 发明申请

WO2006128142A8 INHIBITORS OF CYTOSOLIC PHOSPHOLIPASE A2 审中-公开
标题翻译：胞嘧啶磷脂酶A2抑制剂
公开(公告)号：WO2006128142A8
公开(公告)日：2007-12-27
申请号：PCT/US2006020847
申请日：2006-05-26
申请人： WYETH CORP , MCKEW JOHN C , LEE KATHERINE L , CHEN LIHREN , VARGAS RICHARD , CLARK JAMES D , WILLIAMS CARA , CLERIN VALERIE , MARUSIC SUZANA , PONG KEVIN
发明人： MCKEW JOHN C , LEE KATHERINE L , CHEN LIHREN , VARGAS RICHARD , CLARK JAMES D , WILLIAMS CARA , CLERIN VALERIE , MARUSIC SUZANA , PONG KEVIN
IPC分类号： C07D209/14 , A61K31/404 , A61P11/00 , A61P19/00 , A61P25/00
CPC分类号： C07D209/14 , C07D209/18
摘要： This invention provides chemical inhibitors of the activity of various phospholipase enzymes, particularly cytosolic phospholipase A 2 enzymes (cPLA 2 ), more particularly including inhibitors of cytosolic phospholipase A 2 alpha enzymes (cPLA 2 a). In some embodiments, the inhibitors have the Formula (I): wherein the constituent variables are as defined herein.
摘要翻译：本发明提供了各种磷脂酶，特别是胞质磷脂酶A 2 N 2酶（cPLA 2 N）的活性的化学抑制剂，更具体地包括胞质磷脂酶A 2的抑制剂 α酶（cPLA a a）。在一些实施方案中，抑制剂具有式（I）：其中组分变量如本文所定义。

3. 发明申请

WO2006128142A2 INHIBITORS OF CYTOSOLIC PHOSPHOLIPASE A2 审中-公开
标题翻译： CYPOSOLIC磷脂酶A2抑制剂
公开(公告)号：WO2006128142A2
公开(公告)日：2006-11-30
申请号：PCT/US2006/020847
申请日：2006-05-26
申请人： WYETH , MCKEW, John, C. , LEE, Katherine, L. , CHEN, Lilhren , VARGAS, Richard , CLARK, James, D. , WILLIAMS, Cara , CLERIN, Valerie , MARUSIC, Suzana , PONG, Kevin
发明人： MCKEW, John, C. , LEE, Katherine, L. , CHEN, Lilhren , VARGAS, Richard , CLARK, James, D. , WILLIAMS, Cara , CLERIN, Valerie , MARUSIC, Suzana , PONG, Kevin
IPC分类号： C07D209/14 , A61K31/404 , A61P11/00 , A61P19/00 , A61P25/00
CPC分类号： C07D209/14 , C07D209/18
摘要： This invention provides chemical inhibitors of the activity of various phospholipase enzymes, particularly cytosolic phospholipase A 2 enzymes (cPLA 2 ), more particularly including inhibitors of cytosolic phospholipase A2 alpha enzymes (cPLAα). In some embodiments, the inhibitors have the Formula I: wherein the constituent variables are as defined herein.
摘要翻译：本发明提供了各种磷脂酶，特别是细胞溶质磷脂酶A 2 N 2酶（cPLA 2）的活性的化学抑制剂，更具体地包括胞浆磷脂酶A2α酶抑制剂（cPLAa ）。在一些实施方案中，抑制剂具有式I：其中组成变量如本文所定义。

4. 发明申请

WO1999035551A2 CUSTOM COUPON PROCESS 审中-公开
标题翻译：自定义过程
公开(公告)号：WO1999035551A2
公开(公告)日：1999-07-15
申请号：PCT/US1999000534
申请日：1999-01-04
申请人： CONSUMER NETWORKS INC. , LYONS, Gerald, Ray , SHIRLEY, Terry, Joe , CLARK, James, D.
发明人： CONSUMER NETWORKS INC.
IPC分类号： G06F00/00
CPC分类号： G06Q30/02
摘要： A unique process by which manufacturers and retailers are able to offer coupon savings utilizing the internet or direct mail to customize and deliver unique customer selected coupon savings. In a retailer application, the consumer selections are delivered in one of two manners. If the retailer uses a "frequent shopper card", which is customer specific, formatted data is collected, maintained and transmitted to the retailers' secure interface. The data is then transmitted to the appropriate retailers' point-of-sale system. The consumer selected discounts are deducted from the consumers grocery total after purchase verification and use of the "frequent shopper card". If a "frequent shopper card" is not used by the retailer, a database will collect the selection data, laser print the customer specific coupon selections, imprint each with the appropriate consumer identification and retailer logo, and direct mail the coupons to the consumer. In a completely non-internet application, consumer selections are made, scanned and recorded using a paper selection from delivered through the mail. Regardless of method, all consumer selection data is catalogued, maintained and managed by the database.
摘要翻译：制造商和零售商能够通过互联网或直接邮件提供优惠券节省的独特流程，以定制和提供独特的客户选择的优惠券节省。在零售商应用中，消费者选择以两种方式之一进行交付。如果零售商使用客户特定的“频繁购物卡”，则将格式化数据收集，维护并传送到零售商的安全界面。然后将数据传输到适当的零售商的销售点系统。消费者选择的折扣从购买后的消费者杂货总额中扣除，并使用“频繁购卡者”。如果零售商不使用“频繁的购物卡”，数据库将收集选择数据，激光打印客户特定的优惠券选择，每个印有适当的消费者识别和零售商标志，并将优惠券直接邮寄给消费者。在完全非互联网应用程序中，使用通过邮件传递的纸张选择来进行，扫描和记录消费者选择。不管方法如何，所有消费者选择数据都由数据库编目，维护和管理。

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