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1. 发明申请

WO2009075470A3 GARDEN SHEARS PERFORMING CUTTING STERILIZING OPEERATIONS 审中-公开
标题翻译：花园剪切执行切割杀菌作业
公开(公告)号：WO2009075470A3
公开(公告)日：2009-07-30
申请号：PCT/KR2008006181
申请日：2008-10-20
申请人： B I G CO LTD , CHUNG JONG-SANG
发明人： CHUNG JONG-SANG
IPC分类号： A01G3/02
CPC分类号： A01G3/02
摘要： The present invention relates to garden shears performing cutting and sterilizing operations at the same time including: a pair of shear members having cutting blades and grips formed integrally to each other in a symmetrical relation with each other at left and right sides, each of the grips having an arch-shaped section; a pin-shaped fastening member adapted to hinge-couple the pair of shear members crossed to each other; and a sterilizing liquid tank insertion member formed on the inside of the arch-shaped surface of one side grip in such a manner as to communicate with a sterilizing liquid passageway formed to pass through the inside of the arch-shaped surface of one side grip toward facing portions of the cutting blades facing each other and to make a sterilizing liquid tank detachably attached thereto.
摘要翻译：本发明涉及一种同时进行切割和灭菌操作的园林剪，包括：一对剪切构件，它们具有在左右侧以彼此对称的关系彼此整体形成的切割刀片和把手，每个把手具有拱形部分; 销形紧固构件，其适于将彼此交叉的所述一对剪切构件铰接; 以及消毒液罐插入部件，其形成在一侧把手的弧形表面的内侧上，从而与形成为穿过一侧把手的弧形表面的内部的消毒液体通道相连通面对彼此面对的切割刀片的部分并且使消毒液罐可拆卸地附接到其上。

2. 发明申请

WO2008078905A1 COMPOSITIONS FOR EXTERNAL USE CONTAINING MINOXIDIL FOR HAIR GROWTH WHICH HAVE AN IMPROVED SKIN PERMEABILITY 审中-公开
标题翻译：用于外用的含有氧化铝的组合物用于具有改善的皮肤渗透性的头发生长
公开(公告)号：WO2008078905A1
公开(公告)日：2008-07-03
申请号：PCT/KR2007/006681
申请日：2007-12-20
申请人： CJ CHEILJEDANG CORPORATION , PARK, Choong-sil , KIM, Young-gi , KIM, Chang-ju , KIM, Dal-hyun , HONG, Hye-suk , LEE, Jong-ju , CHUNG, Jong-sang , PARK, Jae-hyun , CHOI, Ha-yong , MAENG, Hyo-chan
发明人： PARK, Choong-sil , KIM, Young-gi , KIM, Chang-ju , KIM, Dal-hyun , HONG, Hye-suk , LEE, Jong-ju , CHUNG, Jong-sang , PARK, Jae-hyun , CHOI, Ha-yong , MAENG, Hyo-chan
IPC分类号： A61K8/49 , A61Q7/00
CPC分类号： A61Q7/00 , A61K8/345 , A61K8/4953 , A61K8/4993
摘要： The present invention relates to a composition for external use containing minoxidil for hair growth with improved skin permeability. The composition of the invention contains one or more active ingredients selected from the group consisting of minoxidil, its derivatives and its salts; one or more co-surfactants selected from the group consisting of glycerin, propyleneglycol and ethanol; and one or more surfactants selected from the group consisting of polysorbate-20 and polysorbate-80, at a required ratio, so that it has excellent skin permeability, compared with the conventional composition for external use for hair growth comprising minoxidil, so as to deliver the active ingredient to target skin tissues more effectively, when it is applied on the skin.
摘要翻译：本发明涉及含有改善皮肤渗透性的毛发生长的米诺地尔的外用组合物。本发明的组合物含有一种或多种选自米诺地尔，其衍生物及其盐的活性成分; 选自甘油，丙二醇和乙醇的一种或多种辅助表面活性剂; 和一种或多种选自聚山梨醇酯-20和聚山梨醇酯-80的表面活性剂，以与所用常规的包含米诺地尔的毛发生长外用组合物相比，具有优异的皮肤渗透性，以便递送当将其施用于皮肤时，有效成分更有效地对准皮肤组织。

3. 发明申请

WO2005054288A1 PROCESS FOR PURIFYING INTERFERON BETA 审中-公开
标题翻译：净化干扰素的方法
公开(公告)号：WO2005054288A1
公开(公告)日：2005-06-16
申请号：PCT/KR2004/003179
申请日：2004-12-04
申请人： CJ CORPORATION , PARK, Ji-Sook , CHUNG, Jong-Sang , BAEK, Min-Ji , AHN, Jee-Won , KIM, Ki-Wan , PARK, Hyung-Ki , LEE, Dong-Eok , OH, Myung-Suk
发明人： PARK, Ji-Sook , CHUNG, Jong-Sang , BAEK, Min-Ji , AHN, Jee-Won , KIM, Ki-Wan , PARK, Hyung-Ki , LEE, Dong-Eok , OH, Myung-Suk
IPC分类号： C07K14/565
CPC分类号： C07K14/565 , C07K5/06139
摘要： Provided is a process for purifying human interferon beta from a recombinant human interferon beta-containing culture comprising performing affinity chromatography and reversed-phase high-performance liquid chromatography (RP-HPLC), wherein the affinity chromatography includes: adsorbing the interferon beta-containing culture to an equilibrated affinity chromatography column, followed by washing with an equilibration buffer solution; washing the column with a washing buffer solution A of pH 6.5-7.5 containing 30-60 wt% of propylene glycol and a washing buffer solution B of pH 6.5-7.5 containing 10-30 wt% of propylene glycol and 1-2M NaCl; and eluting a human interferon beta-containing fraction with a buffer solution of pH 6.5-7.5 containing 40-60 wt% of propylene glycol and 1-2M NaCl.
摘要翻译：提供了一种从重组人类干扰素β培养物中纯化人类干扰素β的方法，包括进行亲和层析和反相高效液相色谱（RP-HPLC），其中亲和层析包括：吸附含有干扰素β的培养物平衡的亲和层析柱，然后用平衡缓冲液洗涤; 用含有30-60重量％丙二醇的pH 6.5-7.5的洗涤缓冲溶液A和pH6.5-7.5的洗涤缓冲液B洗涤柱子，其中含有10-30重量％的丙二醇和1-2M的NaCl; 并用含有40-60重量％丙二醇和1-2M NaCl的pH 6.5-7.5的缓冲溶液洗脱人类含有干扰素β的级分。

4. 发明申请

WO2005054287A1 PROCESS FOR PRODUCING HUMAN INTERFERON ALPHA 审中-公开
标题翻译：生产人间干细胞的方法
公开(公告)号：WO2005054287A1
公开(公告)日：2005-06-16
申请号：PCT/KR2004/003172
申请日：2004-12-03
申请人： CJ CORPORATION , CHUNG, Jong-Sang , BAEK, Min-Ji , AHN, Jee-Won , KIM, Ki-Wan , PARK, Hyung-Ki , LEE, Dong-Eok , LEE, Hyune-Soo , KOH, Hyung-Kon , OH, Myung-Suk
发明人： CHUNG, Jong-Sang , BAEK, Min-Ji , AHN, Jee-Won , KIM, Ki-Wan , PARK, Hyung-Ki , LEE, Dong-Eok , LEE, Hyune-Soo , KOH, Hyung-Kon , OH, Myung-Suk
IPC分类号： C07K14/56
CPC分类号： C07K14/56
摘要： Provided is a process for producing a human interferon alpha, which includes: (a) lysing E. coli cells isolated from a human interferon alpha-producing recombinant E. coli culture, followed by denaturation of interferon alpha and aging; (b) concentrating a solution obtained in operation (a), followed by antibody affinity column chromatography; (c) refolding an eluted solution obtained in operation (b) using an urea-containing buffer solution; (d) performing cation exchange column chromatography of a solution obtained in operation (c); and (e) performing gel-filtration column chromatography of an eluted solution obtained in operation (d). Therefore, an active human interferon alpha can be produced in high yield and purity.
摘要翻译：提供了一种生产人类干扰素α的方法，其包括：（a）裂解从产生人干扰素α的重组大肠杆菌培养物中分离的大肠杆菌细胞，然后使干扰素α变老和老化; （b）浓缩操作（a）中获得的溶液，然后进行抗体亲和柱层析; （c）使用含脲缓冲溶液重新折叠在操作（b）中获得的洗脱溶液; （d）进行在操作（c）中获得的溶液的阳离子交换柱层析; 和（e）对在操作（d）中获得的洗脱溶液进行凝胶过滤柱层析。因此，可以以高产率和纯度生产活性人类干扰素α。

5. 发明申请

WO2009075470A2 GARDEN SHEARS PERFORMING CUTTING STERILIZING OPEERATIONS 审中-公开
标题翻译：园林切割切割灭菌工艺
公开(公告)号：WO2009075470A2
公开(公告)日：2009-06-18
申请号：PCT/KR2008/006181
申请日：2008-10-20
申请人： B.I.G CO., LTD , CHUNG, Jong-Sang
发明人： CHUNG, Jong-Sang
IPC分类号： A01G3/02
CPC分类号： A01G3/02
摘要： The present invention relates to garden shears performing cutting and sterilizing operations at the same time including: a pair of shear members having cutting blades and grips formed integrally to each other in a symmetrical relation with each other at left and right sides, each of the grips having an arch-shaped section; a pin-shaped fastening member adapted to hinge-couple the pair of shear members crossed to each other; and a sterilizing liquid tank insertion member formed on the inside of the arch-shaped surface of one side grip in such a manner as to communicate with a sterilizing liquid passageway formed to pass through the inside of the arch-shaped surface of one side grip toward facing portions of the cutting blades facing each other and to make a sterilizing liquid tank detachably attached thereto.
摘要翻译：本发明涉及同时执行切割和灭菌操作的花园剪，包括：一对剪切构件，其具有在左右两侧彼此成对称关系彼此整体形成的切割刀片和夹具，每个夹具具有拱形部分; 适于将所述一对剪切构件铰接在一起的销形紧固构件，所述剪切构件彼此交叉; 以及一个杀菌液体槽插入件，其形成在一侧夹具的拱形表面的内侧上，以便与形成为穿过一侧手柄的拱形表面的内部的消毒液通道相通切割刀片的面对部分，并且可拆卸地附接到其上的消毒液体罐。

6. 发明申请

WO2005054289A1 PROCESS FOR PURIFYING INTERFERON BETA 审中-公开
标题翻译：净化干扰素的方法
公开(公告)号：WO2005054289A1
公开(公告)日：2005-06-16
申请号：PCT/KR2004/003180
申请日：2004-12-04
申请人： CJ CORPORATION , PARK, Ji-Sook , CHUNG, Jong-Sang , BAEK, Min-Ji , AHN, Jee-Won , KIM, Ki-Wan , PARK, Hyung-Ki , LEE, Dong-Eok , OH, Myung-Suk
发明人： PARK, Ji-Sook , CHUNG, Jong-Sang , BAEK, Min-Ji , AHN, Jee-Won , KIM, Ki-Wan , PARK, Hyung-Ki , LEE, Dong-Eok , OH, Myung-Suk
IPC分类号： C07K14/565
CPC分类号： C07K14/565 , C12P21/02
摘要： Provided is a process for purifying human interferon beta from a recombinant human interferon beta-containing culture comprising performing affinity chromatography and cation exchange chromatography, wherein the affinity chromatography includes: adsorbing the interferon beta-containing culture to an equilibrated affinity chromatography column, followed by washing with an equilibration buffer solution; washing the column with a washing buffer solution A of pH 6.5-7.5 containing 30-60 wt% of propylene glycol and a washing buffer solution B of pH 6.5-7.5 containing 10-30 wt% of propylene glycol and 1-2M NaCl; and eluting a human interferon beta-containing fraction with a buffer solution of pH 6.5-7.5 containing 40-60 wt% of propylene glycol and 1-2M NaCl.
摘要翻译：提供了一种从重组人类干扰素β的培养物中纯化人类干扰素β的方法，包括进行亲和层析和阳离子交换层析，其中亲和层析包括：将含有干扰素β的培养物吸附到平衡的亲和色谱柱上，然后洗涤用平衡缓冲溶液; 用含有30-60重量％丙二醇的pH 6.5-7.5的洗涤缓冲溶液A和pH6.5-7.5的洗涤缓冲液B洗涤柱子，其中含有10-30重量％的丙二醇和1-2M的NaCl; 并用含有40-60重量％丙二醇和1-2M NaCl的pH 6.5-7.5的缓冲溶液洗脱人类含有干扰素β的级分。

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