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1. 发明申请

WO2019062790A1 NOVEL CONJUGATES AND USES THEREOF 审中-公开
公开(公告)号：WO2019062790A1
公开(公告)日：2019-04-04
申请号：PCT/CN2018/107800
申请日：2018-09-27
申请人： LAN, Keng-Li , TSAI, Cheng-Liang
发明人： LAN, Keng-Li , TSAI, Cheng-Liang
IPC分类号： C07K19/00 , A61K38/19 , A61K39/00 , A61P35/00
摘要： Provided herein are novel conjugates and pharmaceutical compositions comprising the novel conjugate described herein. The use of the novel conjugate to inhibit the growth of cancer cells and induce antibody production in a subject in need of cancer treatment, with or without an anti-cancer agent, is also provided.

2. 发明申请

WO2018023748A1 AIR FILTER WITH PASSIVATED FILTER LIFE INDICATOR 审中-公开
标题翻译：带有被动过滤器寿命指示器的空气过滤器
公开(公告)号：WO2018023748A1
公开(公告)日：2018-02-08
申请号：PCT/CN2016/093657
申请日：2016-08-05
申请人： 3M INNOVATIVE PROPERTIES COMPANY , CHENG, Liang
发明人： CHENG, Liang , FOX, Andrew R.
IPC分类号： B01D46/00 , B01D46/52
摘要： An air filter including a visually uniform filter life indicator(30), the air filter(1) comprising: a conformable, unframed air filter media(10) that is installable on at least a portion of an upstream face(11) of a filter-support layer of an air-handling system，wherein the conformable, unframed air filter media comprises at least one passivated area(20) that provides a visually uniform filter life indicator of the air filter. Filter life indicators are used in order that aspects of the filtration performance of an air filter can be monitored.
摘要翻译：一种空气过滤器，包括视觉上均匀的过滤器寿命指示器（30），所述空气过滤器（1）包括：适形的，未成帧的空气过滤器介质（10），所述空气过滤器介质可安装在至少一部分空气处理系统的过滤器支撑层的上游面（11），其中所述适形的，未成帧的空气过滤介质包括提供所述空气过滤器的视觉上均匀的过滤器寿命指示器的至少一个钝化区域（20）。过滤器使用寿命指示器用于监控空气过滤器的过滤性能。

3. 发明申请

WO2012151756A1 TECHNIQUES FOR SYNCHRONIZATION OF AUDIO AND VIDEO 审中-公开
标题翻译：音频和视频同步技术
公开(公告)号：WO2012151756A1
公开(公告)日：2012-11-15
申请号：PCT/CN2011/073994
申请日：2011-05-12
申请人： INTEL CORPORATION , ZENG, Shanjun Oak , HAZELET, Keith , LU, Tiehan , CHENG, Liang Leon , WU, Jie
发明人： ZENG, Shanjun Oak , HAZELET, Keith , LU, Tiehan , CHENG, Liang Leon , WU, Jie
IPC分类号： H04N7/56 , H04N7/52
CPC分类号： H04N9/87 , H04N21/4305 , H04N21/4307 , H04N21/44004
摘要： Techniques are described for determining whether a stream is in a stable state and permitting adjustment of the PTS value when the stream is in a stable state. The stream can be in a stable state when PTS values received over a period of time do not change unexpectedly. For example, when the stream is in a stable state, the PTS value for audio or video can be adjusted based on system buffer levels, i.e., over flow or under flow. The amount of adjustment of the PTS value can be based on whether the buffer level appears to be moving into greater overflow or underflow. In some cases, when the stream is not in a stable state, the audio is permitted to be played back at a sample rate and video is permitted to be played back at a frame rate instead of being controlled by PTS.
摘要翻译：描述了用于确定流是否处于稳定状态并且当流处于稳定状态时允许PTS值的调整的技术。当一段时间内接收的PTS值不会意外改变时，流可以处于稳定状态。例如，当流处于稳定状态时，音频或视频的PTS值可以基于系统缓冲器级别（即，超过流量或不足流量）进行调整。 PTS值的调整量可以基于缓冲区级别是否似乎进入更大的溢出或下溢。在一些情况下，当流不处于稳定状态时，允许以采样率播放音频，并允许视频以帧速率播放，而不是由PTS控制。

4. 发明申请

WO2012092880A1 2,4-DIAMINO-6,7-DIHYDRO-5H-PYRROLO[2,3]PYRIMIDINE DERIVATIVES AS FAK/Pyk2 INHIBITORS 审中-公开
标题翻译： 2,4-二氨基-6,7-二氢-5H-吡咯并[2,3]嘧啶衍生物，以FAK / Pyk2抑制剂
公开(公告)号：WO2012092880A1
公开(公告)日：2012-07-12
申请号：PCT/CN2012/070122
申请日：2012-01-07
申请人： CENTAURUS BIOPHARMA CO., LTD. , XIAO, Dengming , CHENG, Liang , LIU, Xijie , HU, Yuandong , XU, Xinhe , LIU, Zhihua , ZHANG, Lipeng , WU, Wei , WANG, Shulong , SHEN, Yu , LI, Gen , WANG, Yin , ZHAO, Sheng , LI, Chonglong , TANG, Jia , YU, Honghao
发明人： XIAO, Dengming , CHENG, Liang , LIU, Xijie , HU, Yuandong , XU, Xinhe , LIU, Zhihua , ZHANG, Lipeng , WU, Wei , WANG, Shulong , SHEN, Yu , LI, Gen , WANG, Yin , ZHAO, Sheng , LI, Chonglong , TANG, Jia , YU, Honghao
IPC分类号： C07D487/04 , A61K31/505 , A61P35/00 , A61P29/00 , A61P31/00 , A61P37/02
CPC分类号： C07D487/04 , A61K31/4523 , A61K31/519 , A61K31/5377 , A61K31/541 , C07D401/12 , C07D413/12 , C07D417/12 , C07D493/12
摘要： The invention relates to a novel class of 2,4-diamino-6,7-dihydro-5H-pyrrolo[2,3]pyrimidine derivatives as a FAK and/or Pyk2 inhibitor, to a process for their preparation, and to a composition thereof, as well as to use of the compounds for the inhibiting FAK and/or Pyk2 and method for the treatment of a FAK and/ or Pyk2 mediated disorder or disease.
摘要翻译：本发明涉及一种新型的作为FAK和/或Pyk2抑制剂的2,4-二氨基-6,7-二氢-5H-吡咯并[2,3]嘧啶衍生物，其制备方法和组合物以及该化合物用于抑制FAK和/或Pyk2的方法和用于治疗FAK和/或Pyk2介导的病症或疾病的方法。

5. 发明申请

WO2012058812A1 MOP 审中-公开
标题翻译：拖把
公开(公告)号：WO2012058812A1
公开(公告)日：2012-05-10
申请号：PCT/CN2010/078414
申请日：2010-11-04
申请人： 3M INNOVATIVE PROPERTIES COMPANY , ZENG, Feng , JIANG, Weilai , CHENG, Liang , VELLA, Gianmauro
发明人： ZENG, Feng , JIANG, Weilai , CHENG, Liang , VELLA, Gianmauro
IPC分类号： A47L13/258 , A47L13/20
CPC分类号： A47L13/20 , A47L13/256 , A47L13/258
摘要： A mop is disclosed. The mop comprises a mop head (1), a mop shank (2) and a joint (3) connecting the mop head (1) and the mop shank (2), wherein the mop head (1) comprises a cleaning face which is disposed to enable at least one part of the cleaning face to be dynamically switched relative to the other parts thereof, for forming a coplanar state or a non-coplanar state with the other parts.
摘要翻译：披露拖把。拖把包括拖把头（1），拖把柄（2）和连接拖把头（1）和拖把柄（2）的接头（3），其中拖把头（1）包括清洁面设置成使得清洁面的至少一部分相对于其它部分动态地切换，用于与其它部分形成共面状态或非共面状态。

6. 发明申请

WO2011008481A2 COMPOSITE SURFACE CLEANING ARTICLE 审中-公开
标题翻译：复合表面清洁用品
公开(公告)号：WO2011008481A2
公开(公告)日：2011-01-20
申请号：PCT/US2010/040127
申请日：2010-06-28
申请人： 3M INNOVATIVE PROPERTIES COMPANY , DAI, Chongzhi, , CHENG, Liang,
发明人： DAI, Chongzhi, , CHENG, Liang,
IPC分类号： A47L13/08 , A47L13/16
CPC分类号： A47L13/16 , A47L13/18 , B32B5/022 , B32B5/145 , B32B5/22 , B32B5/26 , B32B7/02 , B32B7/12 , B32B2255/02 , B32B2255/26 , B32B2255/28 , B32B2262/0238 , B32B2262/0246 , B32B2262/0253 , B32B2262/0261 , B32B2262/0276 , B32B2262/04 , B32B2262/06 , B32B2262/08 , B32B2264/0235 , B32B2264/0242 , B32B2264/025 , B32B2264/0278 , B32B2264/10 , B32B2264/102 , B32B2264/104 , B32B2307/40 , B32B2307/536 , B32B2307/72 , B32B2432/00 , B32B2437/02 , D04H1/413 , D04H1/4334 , D04H1/645
摘要： Composite surface cleaning articles are disclosed which include a base member which may be a glove or mitten and includes an array of hooks on a portion of an outer surface, and a three zone pad which includes an assembly zone of a low density, open non-woven fibrous structure suitable for joining with the hooks of the base member, a supporting zone adjacent to the assembly zone of an intermediate density, open non-woven fibrous structure, and a cleaning zone adjacent to the supporting zone of a high density, open non-woven fibrous structure and abrasive, wherein the pad is removably attached to the base member.
摘要翻译：公开了复合表面清洁制品，其包括可以是手套或手套的基底构件，并且在外表面的一部分上包括钩状阵列，以及三区垫，其包括低密度，适于与基底构件的钩接合的编织纤维结构，与中密度的开放无纺纤维结构的组装区相邻的支撑区，以及与高密度，开放非织造纤维结构的支撑区相邻的清洁区编织纤维结构和研磨剂，其中垫可移除地附接到基底构件。

7. 发明申请

WO2007098136A3 MEDIUM ACCESS CONTROL METHOD AND DEVICE 审中-公开
标题翻译：中等接入控制方法和设备
公开(公告)号：WO2007098136A3
公开(公告)日：2008-07-03
申请号：PCT/US2007004330
申请日：2007-02-21
申请人： UNIV LEHIGH , PENG JUN , CHENG LIANG
发明人： PENG JUN , CHENG LIANG
IPC分类号： H04L12/413
CPC分类号： H04W28/26 , H04W74/08
摘要： A wireless communications network comprises a plurality of nodes, comprising at least one receiver node; and at least one source node that communicates with the at least one receiver node via a communicating data channel; and a communicating control channel that transmits pulse control information to reserve the data channel for data communication.
摘要翻译：无线通信网络包括多个节点，包括至少一个接收器节点; 以及至少一个源节点，其经由通信数据信道与所述至少一个接收器节点进行通信; 以及发送脉冲控制信息以保留用于数据通信的数据信道的通信控制信道。

8. 发明申请

WO2007035481A1 TREATMENT OF WOOD CHIPS USING ENZYMES 审中-公开
标题翻译：用酶处理木屑
公开(公告)号：WO2007035481A1
公开(公告)日：2007-03-29
申请号：PCT/US2006/036031
申请日：2006-09-15
申请人： ENZYMATIC DEINKING TECHNOLOGIES, L.L.C. , WANG, Xiang, H. , MA, Jian, Hua , JIANG, Cheng, Liang , BROWN, William, D., Jr.
发明人： WANG, Xiang, H. , MA, Jian, Hua , JIANG, Cheng, Liang , BROWN, William, D., Jr.
IPC分类号： D21C5/00
CPC分类号： D21C5/005
摘要： A method of treating wood chips or saw dust with an enzyme formulation, prior to refining, in order to reduce the total extractives content of the wood chips or sawdust and to modify the wood structure is described herein. The wood chips or sawdust are treated with one or more enzymes such as lipases, esterases, pectinases, cellulases, laccases, hemicellulases and combinations thereof. The enzyme formulation can be applied to the surface of the wood chips or sawdust, e.g. by spraying, or can be impregnated into the wood chips. The enzyme formulation can further comprise one or more surface active agents which can enhance the effectiveness of the enzyme treatment by improving the diffusion or impregnation of the enzymes into the wood chips. The enzyme-based treatment can be applied at any of several different locations prior to the pulping process including chip piles, chip conveyors, chip silos, chips washers, chip washer water stream, impregnation liquor, or during chip storage. The enzyme-based treatment is quick and easy to apply in most commercial mill operations. The enzyme-based treatment is effective at temperatures from about 20°C to about 100°C, preferably from about 35°C to about 70°C. The wood chips or saw dust can be treated for a period of time from about 0.10 to about 200 hours, more preferably from about 10 to about 72 hours. The addition of the enzyme formulation into the wood chip or sawdust pile increases the concentration of pitch-degrading enzymes on the chip or dust surfaces which can significantly accelerate the degradation of pitch components inside the chips or sawdust. Decreasing the total extractives content of the wood chips and modifying the structure of the wood chips or sawdust leads to a decrease in the apparent pitch content during pulping and in reduced energy requirements, increased paper strength, improved paper machine runability, and lower costs associated with paper manufacturing.
摘要翻译：本文描述了在精制之前用酶制剂处理木屑或锯屑以减少木屑或锯屑的总提取物含量和改变木结构的方法。用一种或多种酶如脂肪酶，酯酶，果胶酶，纤维素酶，漆酶，半纤维素酶及其组合来处理木屑或锯屑。酶制剂可以施用于木屑或锯屑的表面，例如，通过喷雾，或可以浸渍到木片中。酶制剂还可以包含一种或多种表面活性剂，其可以通过改进酶扩散或浸渍到木片中来增强酶处理的有效性。基于酶的处理可以在制浆过程之前的几个不同位置的任何位置施加，包括芯片堆，切屑输送机，芯片筒仓，切屑洗涤机，切屑清洗机水流，浸渍液或芯片存储期间。基于酶的处理在大多数商业轧机操作中快速且容易地应用。基于酶的处理在约20℃至约100℃，优选约35℃至约70℃的温度下是有效的。木屑或锯屑可以处理约0.10至约200小时，更优选约10至约72小时的时间段。将酶制剂添加到木屑或锯屑堆中增加了芯片或灰尘表面上的沥青降解酶的浓度，这可以显着加速芯片或锯屑中沥青组分的降解。减少木片的总提取物含量和改变木屑或锯屑的结构导致制浆期间表观间距含量的降低以及能量需求降低，纸张强度增加，造纸机运行性能降低以及与纸制造。

9. 发明申请

WO2017143592A1 AIR CONDITIONER FILTER AND METHOD OF MANUFACTURE 审中-公开
标题翻译：空调过滤器和制造方法
公开(公告)号：WO2017143592A1
公开(公告)日：2017-08-31
申请号：PCT/CN2016/074712
申请日：2016-02-26
申请人： 3M INNOVATIVE PROPERTIES COMPANY , CHENG, Liang
发明人： CHENG, Liang , FOX, Andrew R.
IPC分类号： B01D46/10 , F24F13/28
CPC分类号： B01D46/10 , B01D46/0032 , B01D2275/10 , F24F13/28
摘要： Air filters are disclosed. The air filters include filtration media comprising a first surface (104) comprising a first region (106) proximate a first end (110) of the filtration media and a second region (108) proximate a second end (112) of the filtration media. The second region (108) is configured to provide a zone including either a densified zone of the filtration media or a support layer (114) adjacent to the filtration media. Also an air conditioning unit with the air filters is disclosed. And also a method of manufacturing the air filters is disclosed.
摘要翻译：
空气过滤器被披露。空气过滤器包括过滤介质，所述过滤介质包括第一表面（104）和第二区域（108），第一表面（104）包括靠近过滤介质的第一端（110）的第一区域（106）和靠近过滤介质的第二端部（112）的第二区域（108）。第二区域（108）构造成提供包括过滤介质的致密化区域或邻近过滤介质的支撑层（114）的区域。还公开了一种带有空气过滤器的空调单元。还公开了一种制造空气过滤器的方法。

10. 发明申请

WO2012079483A1 PWM COMPARATOR AND CLASS D AMPLIFIER 审中-公开
标题翻译： PWM比较器和D类放大器
公开(公告)号：WO2012079483A1
公开(公告)日：2012-06-21
申请号：PCT/CN2011/083632
申请日：2011-12-07
申请人： CSMC TECHNOLOGIES FAB1 CO., LTD , CSMC TECHNOLOGIES FAB2 CO., LTD. , CHENG, Liang
发明人： CHENG, Liang
IPC分类号： H03F3/217
CPC分类号： H03F3/217 , H03F2200/351 , H03K5/2481
摘要： A pulse width modulation (PWM) comparator and a Class D amplifier are provided. In the PWM comparator, a current feedback mechanism is introduced, which is based on a waveform state of a received high frequency triangle signal and a level state of an output signal of the PWM comparator. The hysteresis of the PWM comparator is changed dynamically, so that the noise resistance ability of the PWM comparator is much better than that of the conventional PWM comparators having a fixed hysteresis. The PWM comparator can operate stably even if the duty cycle of the output signal is nearly 100%.
摘要翻译：提供脉宽调制（PWM）比较器和D类放大器。在PWM比较器中，引入电流反馈机制，其基于接收的高频三角形信号的波形状态和PWM比较器的输出信号的电平状态。 PWM比较器的滞后动态变化，使得PWM比较器的抗噪声能力比具有固定滞后的常规PWM比较器的噪声阻抗能力好得多。即使输出信号的占空比接近100％，PWM比较器也能稳定运行。

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