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1. 发明申请

WO0108262A3 AC/DC ADAPTER 110/230 VOLTS, WITH MULTIPLE DC OUTPUTS 审中-公开
标题翻译： AC / DC适配器110/230伏特，带多个直流输出
公开(公告)号：WO0108262A3
公开(公告)日：2001-05-25
申请号：PCT/SG0000103
申请日：2000-07-21
申请人： CHEN WALTER ROLAND
发明人： CHEN WALTER ROLAND
IPC分类号： H02J1/10 , H02M3/04 , G06F1/26 , H02M7/04
CPC分类号： H02J1/10 , H02M2001/009
摘要： All desktop computers including workstations and servers have internal power supply with DC output of 12 v and 5 v from an AC 110 v/230 v outlet. They do not have a portable AC-DC adapter or an external/internal battery power supply. The laptop computers are powered by internal/external battery or charged simultaneously from an AC 110 v/230 v adapter. Each laptop uses different battery voltages from 10.4 v to 14.8 volts or more, specific to the particular model. The product consists of a combination of three components used as a whole, in combination or as separate individual items/components. The three components are an AC-DC 110 v/ 230 v (30-230 watts or more) adapter with regulated dual DC output of 12 v and 5 v, an AC-DC 110 v/230 v (30-230 watts or more) adapter/charger with regulated DC output of 5 v, 12 v and 16 v and an internal and/or an external low profile DC/DC adapter/converter with variable of fixed DC input of 8 v to 16 v (or wider range) and a regulated multiple DC output of 3.3 v, 5 v and 12 v and/or other regulated multiple DC output voltages. Materials: Hard plastic polymer casing, PCB with components and wiring, DC output jacks. The proposed portable AC/DC adapter 110/230v, of variable wattage, is a new type of AC/DC adapter using 1 or more transformers complete with the circuits for two or more regulated DC outputs and/or a dual DC output of 5v and 12v and a battery charger. A key component is the internal/external low profile DC-DC adapter/converter with variable DC input of 8v to 16v (or wider range) and a multiple regulated variable DC outputs of 3.3v, 5v and 12v and/or other multiple regulated variable DC output voltage combinations.
摘要翻译：包括工作站和服务器在内的所有台式计算机都具有内部电源，DC输出电压为12 v，电压为5 V，交流电源为110 V / 230 V。它们没有便携式AC-DC适配器或外部/内部电池电源。笔记本电脑由内部/外部电池供电，或者从AC 110 v / 230 v适配器同时充电。每台笔记本电脑使用10.4 V至14.8 V或更高的电池电压，特定于特定型号。该产品由组合使用的三个组件组合，组合或独立的单个项目/组件组成。三个组件是具有12V和5V的调节双直流输出的AC-DC 110V / 230V（30-230瓦特或更多）适配器，AC-DC 110V / 230V（30-230瓦特或更多））适配器/充电器，具有5 v，12 v和16 v的稳压直流输出，以及内部和/或外部低配置DC / DC适配器/转换器，具有8 v至16 v（或更宽范围）的固定直流输入，以及3.3V，5V和12V的稳压多路直流输出和/或其它调节的多路直流输出电压。材料：硬塑料聚合物套管，PCB与元件和接线，直流输出插座。所提出的可变功率的便携式AC / DC适配器110 / 230v是一种新型的AC / DC适配器，其使用一个或多个变压器，其具有用于两个或多个稳压DC输出的电路和/或5v的双直流输出， 12v和一个电池充电器。关键部件是内部/外部低调DC-DC适配器/转换器，可变直流输入为8v至16v（或更宽范围），以及3.3v，5v和12v和/或其他多个可调节变量的多调节可变直流输出直流输出电压组合。

2. 发明申请

WO2012051622A3 MICROVESICLE-BASED ASSAYS 审中-公开
公开(公告)号：WO2012051622A3
公开(公告)日：2012-04-19
申请号：PCT/US2011/056589
申请日：2011-10-17
申请人： THE GENERAL HOSPITAL CORPORATION , CHEN, Walter , BREAKEFIELD, Xandra O. , BALAJ, Leonora , SKOG, Johan Karl Olov
发明人： CHEN, Walter , BREAKEFIELD, Xandra O. , BALAJ, Leonora , SKOG, Johan Karl Olov
IPC分类号： C12Q1/68
摘要： Methods are disclosed herein for assaying a biological sample or a bodily fluid obtained from a subject by isolating, obtaining or using a microvesicle fraction from the biological sample or bodily fluid and detecting in the microvesicle fraction the presence or absence of a genetic aberration in an IDH1, IDH2, TP53, PTEN, CDKN2A, NF1, EGFR, RB1, PIK3CA, or BRAF gene. The methods may be used for aiding the diagnosis, prognosis, monitoring, or therapy selection in relation to a disease or other medical condition (e.g., a glioma) in a subject.

3. 发明申请

WO2012051622A2 MICROVESICLE-BASED ASSAYS 审中-公开
标题翻译：基于微波的测定
公开(公告)号：WO2012051622A2
公开(公告)日：2012-04-19
申请号：PCT/US2011056589
申请日：2011-10-17
申请人： GEN HOSPITAL CORP , CHEN WALTER , BREAKEFIELD XANDRA O , BALAJ LEONORA , SKOG JOHAN KARL OLOV
发明人： CHEN WALTER , BREAKEFIELD XANDRA O , BALAJ LEONORA , SKOG JOHAN KARL OLOV
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6827 , C12Q1/6883 , C12Q1/6886 , C12Q2600/118 , C12Q2600/156
摘要： Methods are disclosed herein for assaying a biological sample or a bodily fluid obtained from a subject by isolating, obtaining or using a microvesicle fraction from the biological sample or bodily fluid and detecting in the microvesicle fraction the presence or absence of a genetic aberration in an IDH1, IDH2, TP53, PTEN, CDKN2A, NF1, EGFR, RB1, PIK3CA, or BRAF gene. The methods may be used for aiding the diagnosis, prognosis, monitoring, or therapy selection in relation to a disease or other medical condition (e.g., a glioma) in a subject.
摘要翻译：本文公开了用于分析从受试者获得的生物样品或体液的方法，其通过分离，获得或使用来自生物样品或体液的微泡部分并在微泡部分中检测IDH1中存在或不存在遗传畸变，IDH2，TP53，PTEN，CDKN2A，NF1，EGFR，RB1，PIK3CA或BRAF基因。该方法可以用于辅助与受试者中疾病或其他医学病症（例如神经胶质瘤）相关的诊断，预后，监测或治疗选择。

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