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1. 发明申请

WO2011064562A3 METHOD TO SKRINKPROOF WOOL BY PLASMA POLYMERIZATION 审中-公开
公开(公告)号：WO2011064562A3
公开(公告)日：2011-06-03
申请号：PCT/GB2010/051619
申请日：2010-09-28
申请人： P2i LTD , CARR, Christopher , KHODDAMI, Akbar , COULSON, Stephen
发明人： CARR, Christopher , KHODDAMI, Akbar , COULSON, Stephen
IPC分类号： D06M10/02 , D06M11/79 , D06M14/18 , D06M14/24 , B05D7/24 , D06M101/12
摘要： A method of treating wool in the form of a fibre, yarn, sliver, fabric or garment. A polymer coating is applied by plasma polymerisation to prevent shrinkage due to felting due to laundering. The method may include a pre-treatment step, for example application of a continuous plasma of inert gas, application of nano particles to the fibre surface or coating the fibre surface with a polymer.

2. 发明申请

WO2011064562A2 NOVEL PRODUCT AND METHOD 审中-公开
标题翻译：新产品和方法
公开(公告)号：WO2011064562A2
公开(公告)日：2011-06-03
申请号：PCT/GB2010051619
申请日：2010-09-28
申请人： P2I LTD , CARR CHRISTOPHER , KHODDAMI AKBAR , COULSON STEPHEN
发明人： CARR CHRISTOPHER , KHODDAMI AKBAR , COULSON STEPHEN
CPC分类号： D06C29/00 , D06M10/025 , D06M11/79 , D06M14/18 , D06M14/24 , D06M2101/12 , D06M2200/11 , D06M2200/12 , D06M2200/20 , D06M2200/45
摘要： A method of treating wool in the form of a fibre, yarn, sliver, fabric or garment. A polymer coating is applied by plasma polymerisation to prevent shrinkage due to felting due to laundering. The method may include a pre-treatment step, for example application of a continuous plasma of inert gas, application of nano particles to the fibre surface or coating the fibre surface with a polymer.
摘要翻译：处理纤维，纱线，条子，织物或服装形式的羊毛的方法。通过等离子体聚合来施加聚合物涂层，以防止由于洗涤而引起的熔化引起的收缩。该方法可以包括预处理步骤，例如施加惰性气体的连续等离子体，将纳米颗粒施加到纤维表面或用聚合物涂覆纤维表面。

3. 发明申请

WO1997032873A1 QUINOXALINEDIONES 审中-公开
公开(公告)号：WO1997032873A1
公开(公告)日：1997-09-12
申请号：PCT/EP1997000995
申请日：1997-02-27
申请人： PFIZER RESEARCH AND DEVELOPMENT COMPANY, N.V./S.A. , PFIZER LIMITED , PFIZER INC. , BULL, David, John , CARR, Christopher, Lee , FRAY, Michael, Jonathan , GAUTIER, Elisabeth, Colette, Louise , MOWBRAY, Charles, Eric , STOBIE, Alan
发明人： PFIZER RESEARCH AND DEVELOPMENT COMPANY, N.V./S.A. , PFIZER LIMITED , PFIZER INC.
IPC分类号： C07D401/04
CPC分类号： C07D231/12 , C07D233/56 , C07D249/08 , C07D401/04 , C07D401/14 , C07D403/04 , C07D403/14 , C07D409/14 , C07D413/14 , C07D417/14
摘要： The invention provides compounds of formula (I) and the pharmaceutically acceptable salts thereof, wherein R is a 5-membered ring heteroaryl group containing 3 or 4 nitrogen heteroatoms which is linked to the quinoxalinedione ring by a ring carbon or nitrogen atom, or is a 6-membered ring heteroaryl group containing from 1 to 3 nitrogen heteroatoms which is linked to the quinoxalinedione ring by a ring carbon atom, either of said groups being optionally benzo-fused and optionally substituted, including in the benzo-fused portion, by 1 or 2 substituents each independently selected from C1-C4 alkyl, C2-C4 alkenyl, C3-C7 cycloalkyl, halo, hydroxy, C1-C4 alkoxy, C3-C7 cycloalkyloxy, -COOH, C1-C4 alkoxycarbonyl, -CONR R , -NR R , -S(O)p(C1-C4 alkyl), -SO2NR R , aryl, aryloxy, aryl(C1-C4)alkoxy and het, said C1-C4 alkyl being optionally substituted by C3-C7 cycloalkyl, halo, hydroxy, C1-C4 alkoxy, halo(C1-C4)alkoxy, C3-C7 cycloalkyloxy, C3-C7 cycloalkyl(C1-C4)alkoxy, -COOH, C1-C4 alkoxycarbonyl, -CONR R , -NR R , -S(O)p(C1-C4 alkyl), -SO2(aryl), -SO2NR R , morpholino, aryl, aryloxy, aryl(C1-C4)alkoxy or het, and said C2-C4 alkenyl being optionally substituted by aryl; R and R are each independently selected from H, fluoro, chloro, bromo, C1-C4 alkyl and halo(C1-C4)alkyl; R and R are either each independently selected from H and C1-C4 alkyl or, when taken together, are C5-C7 alkylene; p is 0, 1 or 2; together with the preparation of, compositions containing, the uses of and intermediates used in the synthesis of, such compounds. The compounds are useful as NMDA receptor antagonists for treating acute neurodegenerative and chronic neurological disorders.
摘要翻译：本发明提供式（I）化合物及其药学上可接受的盐，其中R是含有3或4个氮杂原子的5元环杂芳基，其通过环碳或氮原子与喹喔啉二酮环连接，或是含有1至3个氮杂原子的6元环杂芳基，其通过环碳原子与喹喔啉二酮环连接，所述基团任选地被苯并稠合并且任选地被取代，包括苯并稠合部分中的1或 2个独立地选自C 1 -C 4烷基，C 2 -C 4烯基，C 3 -C 7环烷基，卤素，羟基，C 1 -C 4烷氧基，C 3 -C 7环烷氧基，-COOH，C 1 -C 4烷氧羰基，-CONR 3 R R 4，-NR 3 R 4，-S（O）p（C 1 -C 4烷基），-SO 2 NR 3 R 4，芳基，芳氧基，芳基（C 1 -C 4）所述C 1 -C 4烷基任选被C 3 -C 7环烷基，卤素，羟基，C 1 -C 4烷氧基，卤代（C 1 -C 4）烷氧基，C 3 -C 7环烷氧基，C 3 -C 7环烷基（C 1 -C 4）烷氧基，-COOH， C1-C4 烷氧基羰基，-CONR 3 R 4，-NR 3 R 4，-S（O）p（C 1 -C 4烷基），-SO 2（芳基），-SO 2 NR 3 R 4，，吗啉代，芳基，芳氧基，芳基（C 1 -C 4）烷氧基或羟基，所述C 2 -C 4烯基任选被芳基取代; R 1和R 2各自独立地选自H，氟，氯，溴，C 1 -C 4烷基和卤代（C 1 -C 4）烷基; R 3和R 4各自独立地选自H和C 1 -C 4烷基，或者一起是C 5 -C 7亚烷基; p为0,1或2; 以及含有用于合成这些化合物的用途和中间体的组合物的制备。该化合物可用作治疗急性神经变性和慢性神经障碍的NMDA受体拮抗剂。

4. 发明申请

WO2011064562A8 METHOD TO SHRINKPROOF WOOL BY PLASMA POLYMERIZATION 审中-公开
标题翻译：通过等离子体聚合来收缩羊毛的方法
公开(公告)号：WO2011064562A8
公开(公告)日：2011-11-10
申请号：PCT/GB2010051619
申请日：2010-09-28
申请人： P2I LTD , CARR CHRISTOPHER , KHODDAMI AKBAR , COULSON STEPHEN
发明人： CARR CHRISTOPHER , KHODDAMI AKBAR , COULSON STEPHEN
IPC分类号： D06M10/02 , B05D7/24 , D06M11/79 , D06M14/18 , D06M14/24 , D06M101/12
CPC分类号： D06C29/00 , D06M10/025 , D06M11/79 , D06M14/18 , D06M14/24 , D06M2101/12 , D06M2200/11 , D06M2200/12 , D06M2200/20 , D06M2200/45
摘要： A method of treating wool in the form of a fibre, yarn, sliver, fabric or garment. A polymer coating is applied by plasma polymerisation to prevent shrinkage due to felting due to laundering. The method may include a pre-treatment step, for example application of a continuous plasma of inert gas, application of nano particles to the fibre surface or coating the fibre surface with a polymer.
摘要翻译：处理纤维，纱线，条子，织物或服装形式的羊毛的方法。通过等离子体聚合来施加聚合物涂层，以防止由于洗涤而引起的熔化引起的收缩。该方法可以包括预处理步骤，例如施加惰性气体的连续等离子体，将纳米颗粒施加到纤维表面或用聚合物涂覆纤维表面。

5. 发明申请

WO2010062799A3 PERSONALIZED, ONLINE, SCIENTIFIC INTERFACE 审中-公开
标题翻译：个性化，在线，科学界面
公开(公告)号：WO2010062799A3
公开(公告)日：2010-08-19
申请号：PCT/US2009064207
申请日：2009-11-12
申请人： RADIOLOGICAL SOC OF NORTH AMER , KALBFLEISCH BRIAN JOSEPH , CHANG PAUL JOSEPH , DREW STEVEN THOMAS , CARR CHRISTOPHER DANIEL , PEDE DAVID RICHARD , BASCO JOHN WILLIAM , BASCO JAMES FRANCIS
发明人： KALBFLEISCH BRIAN JOSEPH , CHANG PAUL JOSEPH , DREW STEVEN THOMAS , CARR CHRISTOPHER DANIEL , PEDE DAVID RICHARD , BASCO JOHN WILLIAM , BASCO JAMES FRANCIS
IPC分类号： G06Q50/00 , G06F3/00 , G06F15/16
CPC分类号： G06F17/30873 , G06F17/30867
摘要： An Internet-based personalized, online, scientific interface is described, operating from at least a proprietary web server connected to the Internet for sending display images produced at the web server from any software application to a client web browser. The interface is personalized and includes, in addition to providing a gateway to different information databases, a search function, an archiving function, a specific bookmark function, an access to uploaded abstracts, and a personalized area. The interface includes a tool for upload, creation, venue presentation, and highly interactive web delivery presentation of a scientific paper or a poster by an author, linked with an internal tool for reviewing, accepting, and grading submitted abstracts for review. Within the personalized page, the interface includes a management tool for all abstracts uploaded to the interface, a follow-up tool and a system for managing the academic currency associated with the uploaded presentations including the capacity to produce feedback report associated with comments and viewing statistics. A digital presentation system allows attendees to comment on specific slides of presentations, have live or deferred communications with the presenter, rate the presentation, and even archive part or all of the presentation in the interface for later retrieval.
摘要翻译：描述了基于因特网的个性化在线科学界面，其至少从连接到因特网的专有网络服务器进行操作，用于将从网络服务器产生的显示图像从任何软件应用程序发送到客户端网络浏览器。该界面是个性化的，并且除了提供到不同信息数据库的网关之外，还包括搜索功能，存档功能，特定书签功能，对上传摘要的访问以及个性化区域。该界面包含一个工具，用于上传，创建，场地演示以及作者发表科学论文或海报的高度互动式网页交付演示，并与内部工具链接，用于审阅，接受和分级提交的摘要以供审阅。在个性化页面中，界面包括用于上传到界面的所有摘要的管理工具，后续工具和用于管理与上传的演示文稿相关联的学术货币的系统，包括生成与评论和查看统计相关联的反馈报告的能力。数字演示系统允许与会者对演示文稿的特定幻灯片发表评论，与演示者进行直播或延迟沟通，对演示评分，甚至将界面中的部分或全部演示文档归档以供以后检索。

6. 发明申请

WO2010062799A2 PERSONALIZED, ONLINE, SCIENTIFIC INTERFACE 审中-公开
标题翻译：个性化，在线，科学界面
公开(公告)号：WO2010062799A2
公开(公告)日：2010-06-03
申请号：PCT/US2009/064207
申请日：2009-11-12
申请人： RADIOLOGICAL SOCIETY OF NORTH AMERICA, INC. , KALBFLEISCH, Brian, Joseph , CHANG, Paul, Joseph , DREW, Steven, Thomas , CARR, Christopher, Daniel , PEDE, David, Richard , BASCO, John, William , BASCO, James, Francis
发明人： KALBFLEISCH, Brian, Joseph , CHANG, Paul, Joseph , DREW, Steven, Thomas , CARR, Christopher, Daniel , PEDE, David, Richard , BASCO, John, William , BASCO, James, Francis
IPC分类号： G06Q50/00 , G06F3/00 , G06F15/16
CPC分类号： G06F17/30873 , G06F17/30867
摘要： An Internet-based personalized, online, scientific interface is described, operating from at least a proprietary web server connected to the Internet for sending display images produced at the web server from any software application to a client web browser. The interface is personalized and includes, in addition to providing a gateway to different information databases, a search function, an archiving function, a specific bookmark function, an access to uploaded abstracts, and a personalized area. The interface includes a tool for upload, creation, venue presentation, and highly interactive web delivery presentation of a scientific paper or a poster by an author, linked with an internal tool for reviewing, accepting, and grading submitted abstracts for review. Within the personalized page, the interface includes a management tool for all abstracts uploaded to the interface, a follow-up tool and a system for managing the academic currency associated with the uploaded presentations including the capacity to produce feedback report associated with comments and viewing statistics. A digital presentation system allows attendees to comment on specific slides of presentations, have live or deferred communications with the presenter, rate the presentation, and even archive part or all of the presentation in the interface for later retrieval.
摘要翻译：描述了基于因特网的个性化的在线科学界面，至少从连接到因特网的专用网络服务器运行，用于将从web服务器生成的显示图像从任何软件应用发送到客户端web浏览器。该界面是个性化的，并且除了提供到不同信息数据库的网关之外，还包括搜索功能，归档功能，特定书签功能，对上传的摘要的访问以及个性化区域。该界面包括一个用于上传，创建，场地演示以及由作者高度互动的科学论文或海报的交互式工具，与内部工具链接，用于审查，接受和分级提交的摘要以供审核。在个性化页面中，界面包括用于上传到界面的所有摘要的管理工具，后续工具和用于管理与上传的演示文稿相关联的学术货币的系统，包括产生与评论和查看统计信息相关联的反馈报告的能力。数字演示系统允许与会者对演示文稿的特定幻灯片进行评论，与演示者进行实时或延迟通信，对演示进行评估，甚至归档界面中的部分或全部演示文稿以供以后检索。

7. 发明申请

WO2003039279A2 METHOD OF IMPROVING RESISTANCE TO ABRASION IN GARMENTS 审中-公开
标题翻译：改善服装磨损耐受性的方法
公开(公告)号：WO2003039279A2
公开(公告)日：2003-05-15
申请号：PCT/GB2002/005035
申请日：2002-11-07
申请人： MARKS AND SPENCER PLC , CARR, Christopher, Michael , NATH, Sona, Swamima
发明人： CARR, Christopher, Michael , NATH, Sona, Swamima
IPC分类号： A41D
CPC分类号： D06M23/18 , D06M10/001 , D06M15/564 , D06M15/59 , D06M2200/35
摘要： A method of producing a garment or other fabric article having increased resistance to wet or dry abrasion, particularly at edge portions, comprises constructing at least those portions of the article having an abradable edge using pre-treated fabric, or untreated fabric and then subsequently treating the fabric during the course of the manufacture of the article, said treatment comprising treatment with (a) an epichlorohydrin adduct of a polyamide-polyamine derived from a dicarboxylic acid and a dihydrocarbon triamine, in particular a polyamide-polyamine having a repeating unit of the general formula (I); wherein R 1 is present or absent and R 1 (when present), R 2 and R 3 are each independently an alkylene group with 1-4 carbon atoms or an arylene group; or with (b) a UV-curable high molecular weight urethane acrylate or dimethacrylate resin; and subsequent curing by heat or UV-radiation respectively.
摘要翻译：制造具有增加的抗湿性或干性磨损性，尤其是边缘部分的衣服或其它织物制品的方法包括使用预处理的织物或未经处理的织物至少构成具有可磨损边缘的制品的至少部分，然后随后处理所述处理包括用（a）由二羧酸衍生的聚酰胺 - 多胺和二氢碳酸三胺的表氯醇加合物，特别是具有重复单元的聚酰胺 - 多胺通式（I）; 其中R 1存在或不存在，R 1（当存在时），R 2和R 3各自独立地为具有1-4个碳原子的亚烷基或亚芳基; 或（b）UV固化型高分子量聚氨酯丙烯酸酯或二甲基丙烯酸酯树脂; 然后分别通过热或UV辐射固化。

8. 发明申请

WO1996005355A3 WOOL PRE-TREATMENT METHOD 审中-公开
公开(公告)号：WO1996005355A3
公开(公告)日：1996-02-22
申请号：PCT/GB1995001862
申请日：1995-08-07
申请人： THE UNIVERSITY OF MANCHESTER INSTITUTE OF SCIENCE AND TECHNOLOGY , CARR, Christopher, Michael , DODD, Kevin, James
发明人： THE UNIVERSITY OF MANCHESTER INSTITUTE OF SCIENCE AND TECHNOLOGY
IPC分类号： D06M11/09

9. 发明申请

WO9605355A2 WOOL PRE-TREATMENT METHOD 审中-公开
标题翻译：羊毛预处理方法
公开(公告)号：WO9605355A2
公开(公告)日：1996-02-22
申请号：PCT/GB9501862
申请日：1995-08-07
申请人： UNIV MANCHESTER , CARR CHRISTOPHER MICHAEL , DODD KEVIN JAMES
发明人： CARR CHRISTOPHER MICHAEL , DODD KEVIN JAMES
IPC分类号： D06M11/09 , D06M15/643
CPC分类号： D06M15/6436 , D06M11/09 , D06M2101/12 , D06M2200/45
摘要： Keratin-containing fabric is treated by exposing it to a fluorine-containing gas for a relatively short time, for example 60 seconds or substantially less, by passing the fabric continuously through an atmosphere containing fluorine gas. The fluorine content of the gas to which the fabric is exposed can be relatively low, for example 3 %. The fluorinated fabric may be treated with a polymer such as an amino polysiloxane, and when so treated is protected against shrinkage and maintains good fabric mechanical properties.
摘要翻译：通过将织物连续通过含氟气体的气氛将含有织物的织物暴露于相对较短的时间，例如60秒或更小的处理。织物暴露的气体的氟含量可以相对较低，例如3％。氟化织物可以用诸如氨基聚硅氧烷的聚合物处理，并且当这样处理被保护以防止收缩并保持良好的织物机械性能。

10. 发明申请

WO1996008485A1 QUINOXALINEDIONE NMDA RECEPTOR ANTAGONISTS 审中-公开
标题翻译：喹唑啉酮NMDA受体拮抗剂
公开(公告)号：WO1996008485A1
公开(公告)日：1996-03-21
申请号：PCT/EP1995003483
申请日：1995-09-01
申请人： PFIZER LIMITED , PFIZER RESEARCH AND DEVELOPMENT COMPANY, N.V./S.A. , PFIZER INC. , MOWBRAY, Charles, Eric , STOBIE, Alan , BULL, David, John , CARR, Christopher, Lee , FRAY, Michael, Johnathan
发明人： PFIZER LIMITED , PFIZER RESEARCH AND DEVELOPMENT COMPANY, N.V./S.A. , PFIZER INC.
IPC分类号： C07D403/06
CPC分类号： C07D403/06
摘要： Compounds of formula (I) wherein R and R are each independently F, Cl, Br, CH3, CH2CH3 or CF3; R is H, CH3 or CH2CH3; and X is a 5-membered heterocyclic group containing up to four nitrogen atoms, attached via a nitrogen atom, the said group being optionally benzofused and/or substituted by C1-C6 alkyl or (CH2)nNR R , wherein n is an integer from 1 to 5 and R and R are each independently H, C1-C6 alkyl, C3-C6 cycloalkyl or C1-C4 alkyl substituted by phenyl or pyridyl, or R and R are linked to form, together with the nitrogen atom to which they are attached, a pyrrolidine, piperidine, piperazine, N-(C1-C4 alkyl) piperazine, morpholine or azepine group; and their pharmaceutically acceptable salts, are NMDA antagonists of utility in the treatment of acute neurodegenerative disorders, e.g. arising from stroke or traumatic head injury and in chronic neurological disorders, e.g. senile dementia and Alzheimer's disease.
摘要翻译：其中R 1和R 2各自独立地为F，Cl，Br，CH 3，CH 2 CH 3或CF 3的式（I）化合物; R 3是H，CH 3或CH 2 CH 3; X是通过氮原子连接至多四个氮原子的5元杂环基，所述基团任选被C 1 -C 6烷基或（CH 2）n NR 4 R 5苯并稠合和/或取代，其中n为1至5的整数，R 4和R 5各自独立地为H，C 1 -C 6烷基，C 3 -C 6环烷基或被苯基或吡啶基取代的C 1 -C 4烷基，或R 4和 R 5与其连接的氮原子一起形成吡咯烷，哌啶，哌嗪，N-（C 1 -C 4烷基）哌嗪，吗啉或吖庚因基团; 和它们的药学上可接受的盐，是用于治疗急性神经变性疾病的NMDA拮抗剂。由中风或创伤性头部损伤和慢性神经障碍引起的，例如，老年痴呆和阿尔茨海默病。

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