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1. 发明申请

WO2012154985A2 AV NODAL STIMULATION DURING ATRIAL TACHYARRHYTHMIA TO PREVENT INAPPROPRIATE THERAPY DELIVERY 审中-公开
标题翻译：急性心肌梗塞期间的AV NODAL刺激，以防止不准确的治疗方案
公开(公告)号：WO2012154985A2
公开(公告)日：2012-11-15
申请号：PCT/US2012/037371
申请日：2012-05-10
申请人： MEDTRONIC, INC. , WARMAN, Eduardo N. , BURNES, John E. , MICHELS, Koen J. , ZIEGLER, Paul D. , KORNET, Lilian
发明人： WARMAN, Eduardo N. , BURNES, John E. , MICHELS, Koen J. , ZIEGLER, Paul D. , KORNET, Lilian
IPC分类号： A61N1/362 , A61N1/36
CPC分类号： A61N1/3622 , A61N1/36053 , A61N1/36114 , A61N1/3621 , A61N1/3624
摘要： The disclosure describes techniques for delivering electrical stimulation to decrease the ventricular rate response during an atrial tachyarrhythmia, such as atrial fibrillation. AV nodal stimulation is employed during an atrial tachyarrhythmia episode with rapid ventricular conduction to distinguish ventricular tachyarrhythmia from supraventricular tachycardia and thereby prevent delivering inappropriate therapy to a patient.
摘要翻译：本公开描述了用于递送电刺激以降低心房速发性心律失常（例如心房颤动）期间的心室率反应的技术。在室性快速性心律失常发作期间采用AV淋巴结刺激，其具有快速的心室传导以区分室上性快速性心律失常与室上性心动过速，从而阻止对患者递送不适当的治疗。

2. 发明申请

WO2010051425A3 IMPLANTABLE MEDICAL DEVICE CROSSTALK EVALUATION AND MITIGATION 审中-公开
标题翻译：可植入医疗设备串扰评估和缓解
公开(公告)号：WO2010051425A3
公开(公告)日：2010-06-24
申请号：PCT/US2009062719
申请日：2009-10-30
申请人： MEDTRONIC INC , KRAUSE PAUL G , BURNES JOHN E , DONOFRIO WILLIAM T , PEICHEL DAVID J , ARNE GERALD P , ZHOU XIAOHONG , REINKE JAMES D , DAVIS TIMOTHY
发明人： KRAUSE PAUL G , BURNES JOHN E , DONOFRIO WILLIAM T , PEICHEL DAVID J , ARNE GERALD P , ZHOU XIAOHONG , REINKE JAMES D , DAVIS TIMOTHY
IPC分类号： A61N1/362 , A61N1/36 , A61N1/368 , A61N1/372
CPC分类号： A61N1/3622 , A61N1/36114 , A61N1/36185 , A61N1/3686 , A61N1/3688
摘要： Electrical crosstalk between two implantable medical devices or two different therapy modules of a common implantable medical device may be evaluated, and, in some examples, mitigated. In some examples, one of the implantable medical devices or therapy modules delivers electrical stimulation to a nonmyocardial tissue site or a nonvascular cardiac tissue site, and the other implantable medical device or therapy module delivers cardiac rhythm management therapy to a heart of the patient.
摘要翻译：可以评估两个可植入医疗装置或常见可植入医疗装置的两个不同治疗模块之间的电串扰，并且在一些示例中可以减轻。在一些示例中，可植入医疗设备或治疗模块中的一个将电刺激递送至非心肌组织部位或非脉管心脏组织部位，并且另一个可植入医疗设备或治疗模块将心律管理治疗递送至患者的心脏。

3. 发明申请

WO2010051495A1 IMPLANTABLE MEDICAL DEVICE LEAD CONNECTION ASSEMBLY 审中-公开
标题翻译：可植入医疗设备引线连接总成
公开(公告)号：WO2010051495A1
公开(公告)日：2010-05-06
申请号：PCT/US2009/062857
申请日：2009-10-30
申请人： MEDTRONIC, INC. , DONOFRIO, William, T. , BURNES, John, E. , KRAUSE, Paul, G.
发明人： DONOFRIO, William, T. , BURNES, John, E. , KRAUSE, Paul, G.
IPC分类号： A61N1/375
CPC分类号： A61N1/3752 , H01R13/5224 , H01R24/58 , H01R2107/00 , H01R2201/12 , Y10S439/909
摘要： A lead connection assembly of an implantable medical device (IMD) may include at least two different types of electrical connectors. In some examples, the lead connection assembly may include first and second electrical connectors that have at least one of a different electrical contact arrangement, a different lead connection receptacle geometry or a different size than the first electrical connector. The first electrical connector may be electrically connected to a first therapy module that generates cardiac rhythm therapy that is delivered to a heart of a patient, and the second electrical connector may be electrically connected to a second therapy module that generates electrical stimulation that is delivered to a tissue site within the patient. The second electrical connector may be configured to be incompatible with a lead that delivers the cardiac rhythm therapy to the patient.
摘要翻译：可植入医疗装置（IMD）的引线连接组件可以包括至少两种不同类型的电连接器。在一些示例中，引线连接组件可以包括具有与第一电连接器不同的电接触布置，不同引线连接插座几何形状或不同尺寸中的至少一个的第一和第二电连接器。第一电连接器可以电连接到第一治疗模块，该第一治疗模块产生被递送到患者的心脏的心律疗法，并且第二电连接器可以电连接到产生电刺激的第二治疗模块，该电刺激被递送到患者内的组织部位。第二电连接器可以被配置为与将心律治疗递送给患者的引线不相容。

4. 发明申请

WO2010051482A3 INTERFERENCE MITIGATION FOR IMPLANTABLE DEVICE RECHARGING 审中-公开
公开(公告)号：WO2010051482A3
公开(公告)日：2010-05-06
申请号：PCT/US2009/062833
申请日：2009-10-30
申请人： MEDTRONIC, INC. , KRAUSE, Paul, G. , DONOFRIO, William, T. , ARNE, Gerald, P. , REINKE, James, D. , PEICHEL, David, J. , DAVIS, Timothy , BURNES, John, E.
发明人： KRAUSE, Paul, G. , DONOFRIO, William, T. , ARNE, Gerald, P. , REINKE, James, D. , PEICHEL, David, J. , DAVIS, Timothy , BURNES, John, E.
IPC分类号： A61N1/378 , A61N1/372 , A61N1/37 , H02J7/02
摘要： A therapy or monitoring system may implement one or more techniques to mitigate interference between operation of a charging device that charges a first implantable medical device (IMD) implanted in a patient and a second IMD implanted in the patient. In some examples, the techniques may include modifying an operating parameter of the charging device in response to receiving an indication that a second IMD is implanted in the patient. The techniques also may include modifying an operating parameter of the second IMD in response to detecting the presence or operation of the charging device.

5. 发明申请

WO2010051475A1 IMPLANTABLE MEDICAL DEVICE CROSSTALK EVALUATION AND MITIGATION 审中-公开
公开(公告)号：WO2010051475A1
公开(公告)日：2010-05-06
申请号：PCT/US2009/062822
申请日：2009-10-30
申请人： MEDTRONIC, INC. , DONOFRIO, William, T. , BURNES, John, E. , KRAUSE, Paul, G. , ARNE, Gerald, P. , PEICHEL, David, J. , ZHOU, Xiaohong , REINKE, James, D. , DAVIS, Timothy
发明人： DONOFRIO, William, T. , BURNES, John, E. , KRAUSE, Paul, G. , ARNE, Gerald, P. , PEICHEL, David, J. , ZHOU, Xiaohong , REINKE, James, D. , DAVIS, Timothy
IPC分类号： A61N1/365 , A61B5/053 , A61N1/36 , A61N1/39 , A61N1/372 , A61N1/368
CPC分类号： A61N1/0551 , A61N1/36114 , A61N1/3621 , A61N1/36521 , A61N1/37 , A61N1/37247 , A61N1/37282 , A61N1/3962 , A61N2001/083
摘要： Electrical crosstalk between two implantable medical devices or two different therapy modules of a common implantable medical device may be evaluated, and, in some examples, mitigated. In some examples, one of the implantable medical devices or therapy modules delivers electrical stimulation to a nonmyocardial tissue site or a nonvascular cardiac tissue site, and the other implantable medical device or therapy module delivers cardiac rhythm management therapy to a heart of the patient.

6. 发明申请

WO2010051467A1 IMPLANTABLE MEDICAL DEVICE CROSSTALK EVALUATION AND MITIGATION 审中-公开
公开(公告)号：WO2010051467A1
公开(公告)日：2010-05-06
申请号：PCT/US2009/062808
申请日：2009-10-30
申请人： MEDTRONIC, INC. , BURNES, John, E. , KRAUSE, Paul, G. , DONOFRIO, William, T. , PEICHEL, David, J. , ARNE, Gerald, P. , ZHOU, Xiaohong , REINKE, James, D.
发明人： BURNES, John, E. , KRAUSE, Paul, G. , DONOFRIO, William, T. , PEICHEL, David, J. , ARNE, Gerald, P. , ZHOU, Xiaohong , REINKE, James, D.
IPC分类号： A61N1/365 , A61B5/053 , A61N1/36 , A61N1/39
CPC分类号： A61N1/37 , A61N1/3605 , A61N1/36114 , A61N1/36521 , A61N1/37258 , A61N1/37288
摘要： Electrical crosstalk between two implantable medical devices or two different therapy modules of a common implantable medical device may be evaluated, and, in some examples, mitigated. In some examples, one of the implantable medical devices or therapy modules delivers electrical stimulation to a nonmyocardial tissue site or a nonvascular cardiac tissue site, and the other implantable medical device or therapy module delivers cardiac rhythm management therapy to a heart of the patient.

7. 发明申请

WO2009134960A3 EXTRA-CARDIAC IMPLANTABLE DEVICE WITH FUSION PACING CAPABILITY 审中-公开
标题翻译：具有融合能力的外部可植入装置
公开(公告)号：WO2009134960A3
公开(公告)日：2010-04-08
申请号：PCT/US2009042217
申请日：2009-04-30
申请人： MEDTRONIC INC , BURNES JOHN E , DOLAN BECKY L
发明人： BURNES JOHN E , DOLAN BECKY L
IPC分类号： A61N1/368
CPC分类号： A61N1/368 , A61N1/0587 , A61N1/3682
摘要： According to this disclosure, a non-transvenous pacing and, optionally defibrillation, therapy device is implanted subcutaneously and oriented to provide cardiac sensing from electrodes spaced from a heart and deliver pacing and/or defibrillation from 0.one or more non-transvenous electrodes (e.g., an epicardial or pericardial electrode or electrode patch). A subject receiving a device according to this disclosure is monitored to confirm a relatively stable bundle branch block (i.e., delayed activation) of one ventricle. The subcutaneous device has electrodes disposed on the housing and/or having an electrode on a subcutaneous medical lead is oriented so that the pacing (and sensing) vector impinges mainly upon the one ventricle, and/or optionally an epicardial or pericardial lead is deployed to a last-to-depolarize ventricle (e.g., a left ventricle) so that single-ventricular pacing is delivered to achieve fusion depolarization of both ventricles.
摘要翻译：根据本公开，非静脉起搏和（可选地除颤）疗法装置被植入皮下并定向以提供来自与心脏间隔开的电极的心脏感测，并且从一个或多个非经静脉电极输送起搏和/或除颤例如，心外膜或心包电极或电极贴片）。监测接收根据本公开的装置的受试者以确认一个心室的相对稳定的束支传导阻滞（即，延迟激活）。皮下装置具有设置在壳体上和/或具有皮下医疗引线上的电极的电极被定向成使得起搏（和感测）载体主要照射在一个心室上，和/或可选地将心外膜或心包引线部署到最终到去极化的心室（例如，左心室），以便输送单心室起搏以实现两个心室的融合去极化。

8. 发明申请

WO2009135089A1 TECHNIQUES FOR PLACING MEDICAL LEADS FOR ELECTRICAL STIMULATION OF NERVE TISSUE 审中-公开
标题翻译：用于放置用于电刺激神经组织的医用引线的技术
公开(公告)号：WO2009135089A1
公开(公告)日：2009-11-05
申请号：PCT/US2009/042447
申请日：2009-04-30
申请人： MEDTRONIC, INC. , BURNES, John, E. , GARDESKI, Kenneth, C. , KLEPFER, Ruth, N. , MACAULAY, Patrick, E. , MORRIS, Mary, M. , SCHEINER, Avram
发明人： BURNES, John, E. , GARDESKI, Kenneth, C. , KLEPFER, Ruth, N. , MACAULAY, Patrick, E. , MORRIS, Mary, M. , SCHEINER, Avram
IPC分类号： A61N1/05 , A61M25/06
CPC分类号： A61N1/36053 , A61M25/09 , A61N1/05 , A61N1/0551 , A61N1/0558 , A61N1/057 , A61N1/36085 , A61N1/36114 , A61N1/36125 , A61N1/36128
摘要： This disclosure is directed to extra, intra, and transvascular medical lead placement techniques for arranging medical leads and electrical stimulation and/or sensing electrodes proximate nerve tissue within a patient. It discloses a system for implantation of a medical lead configured to deliver electrical stimulation to nerve tissue located adjacent a blood vessel, the system comprising: a catheter adapted to be positioned within a lumen of the blood vessel adjacent the nerve tissue; a deployment member extendable and retractable from the catheter through a wall of the blood vessel lumen; and an electrode connected to the deployment member such that the deployment member positions the electrode outside of the blood vessel proximate the nerve tissue when the deployment member is extended through the lumen wall.
摘要翻译：本公开涉及用于在患者体内靠近神经组织布置医疗引线和电刺激和/或感测电极的额外的，内部的和经血管内的医疗引线放置技术。它公开了用于植入医疗引线的系统，其被配置为将电刺激递送到位于血管附近的神经组织，所述系统包括：适于定位在与神经组织相邻的血管的腔内的导管; 展开构件，其从所述导管延伸并且可从所述血管内腔的壁延伸; 以及连接到所述展开构件的电极，使得当所述展开构件延伸穿过所述管腔壁时，所述展开构件将所述电极定位在靠近所述神经组织的血管外部。

9. 发明申请

WO2009135075A1 TECHNIQUES FOR PLACING MEDICAL LEADS FOR ELECTRICAL STIMULATION OF NERVE TISSUE 审中-公开
标题翻译：用于放置用于电刺激神经组织的医用引线的技术
公开(公告)号：WO2009135075A1
公开(公告)日：2009-11-05
申请号：PCT/US2009/042427
申请日：2009-04-30
申请人： MEDTRONIC, INC. , BURNES, John, E. , MORRIS, Mary, M. , BONNER, Matthew, David , HILL, Michael, R.s. , SCHEINER, Avram , KLEPFER, Ruth, N.
发明人： BURNES, John, E. , MORRIS, Mary, M. , BONNER, Matthew, David , HILL, Michael, R.s. , SCHEINER, Avram , KLEPFER, Ruth, N.
IPC分类号： A61N1/05 , A61M25/06 , A61B17/34 , A61M25/00
CPC分类号： A61N1/36053 , A61M25/09 , A61N1/05 , A61N1/0551 , A61N1/0558 , A61N1/057 , A61N1/36085 , A61N1/36114 , A61N1/36125 , A61N1/36128
摘要： This disclosure is directed to extra, intra, and transvascular medical lead placement techniques for arranging medical leads and electrical stimulation and/or sensing electrodes proximate nerve tissue within a patient. It discloses an implantable medical lead system configured to deliver electrical stimulation to nerve tissue within a patient, the system comprising: an implantable medical lead comprising a distal portion configured for introduction into a sheath of tissue that contains the nerve tissue; an electrode electrically connected to the distal portion of the implantable medical lead; and an anchor connected to the medical lead and proximally offset from the electrode at least partially outside of the sheath to stabilize placement of the distal portion of the lead within the sheath.
摘要翻译：本公开涉及用于在患者体内靠近神经组织布置医疗引线和电刺激和/或感测电极的额外的，内部的和经血管内的医疗引线放置技术。其公开了一种被配置为向患者内的神经组织递送电刺激的可植入医疗引线系统，所述系统包括：可植入医疗引线，其包括构造成引入到包含所述神经组织的组织鞘中的远端部分; 电连接到所述可植入医疗引线的远端部分的电极; 以及锚固件，其连接到医疗引线并且至少部分地至少部分地位于护套的外侧并从电极向近侧偏移，以稳定引线的远侧部分在护套内的放置。

10. 发明申请

WO2006115774A8 SYSTEM FOR ENHANCED CARDIAC FUNCTION WITH COMBINED PESP/NES 审中-公开
标题翻译：具有组合PESP / NES的增强心脏功能的系统
公开(公告)号：WO2006115774A8
公开(公告)日：2008-06-19
申请号：PCT/US2006013592
申请日：2006-04-11
申请人： MEDTRONIC INC , BURNES JOHN E , MULLIGAN LAWRENCE J , KNOLL RANDALL L
发明人： BURNES JOHN E , MULLIGAN LAWRENCE J , KNOLL RANDALL L
IPC分类号： A61N1/362
CPC分类号： A61N1/3627 , A61N1/36114 , A61N1/36564

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