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1. 发明申请

WO2011089534A2 DEVICE FOR DISPENSING A PLURALITY OF UNITARY DOSES OF DRY POWDER, AND INHALER COMPRISING SUCH DEVICE 审中-公开
标题翻译：用于分配多个单剂量干粉的装置和包含这种装置的吸入器
公开(公告)号：WO2011089534A2
公开(公告)日：2011-07-28
申请号：PCT/IB2011/050048
申请日：2011-01-06
申请人： PFIZER LIMITED , BOWMAN, Nicholas John , REILLY, Declan
发明人： BOWMAN, Nicholas John , REILLY, Declan
IPC分类号： A61M15/00
CPC分类号： A61M15/0045 , A47G2019/122 , A61M15/00 , A61M15/0028 , A61M15/0031 , A61M15/0048 , A61M15/0061 , A61M15/0068 , A61M2202/064 , B01F13/1058
摘要： Device for dispensing a plurality of unitary doses (2) of dry powder, comprising at least one support comprising conduits each defining a flow path for an airstream carrying one of the unitary dose (2), the support having first (26) and second (27) members secured to one another so that a first conduit portion (29) of the first member faces a second conduit portions (43) of the second member to define one of the conduits, and a first separation portion (30) of the first member faces a second separation portions (45) of the second member, the support comprising a plurality of barrier-forming elements (31, 46) each arranged between corresponding first (30) and second (45) separation portions to prevent dry powder from passing from one of the conduits to one of the adjacent conduits.
摘要翻译：用于分配干燥粉末的多个单一剂量（2）的装置，包括至少一个支撑件，所述支撑件包括导管，每个支撑件限定用于携带所述单一剂量（2）中的一个的气流的流动路径，所述支撑件具有彼此固定的第一部件（26）和第二部件（27），使得第一部件的第一管道部分（29）面向第二部件的第二管道部分（43）以限定其中一个管道，并且第一部件所述第一构件的分隔部分（30）面向所述第二构件的第二分隔部分（45），所述支撑件包括多个分别布置在相应的第一（30）和第二（45）分隔件之间的阻挡形成元件（31,46）分离部分以防止干粉从其中一个导管流向相邻导管之一。

2. 发明申请

WO2004009471A2 INHALER VALVE MECHANISM 审中-公开
标题翻译：吸入阀机构
公开(公告)号：WO2004009471A2
公开(公告)日：2004-01-29
申请号：PCT/GB0303139
申请日：2003-07-18
申请人： THE TECHNOLOGY PARTNERSHIP PLC , GUTSELL GRAHAM SCOTT , BOWMAN NICHOLAS JOHN , MCDERMENT IAIN GRIERSON , CAMPBELL PATRICK JAMES
发明人： GUTSELL GRAHAM SCOTT , BOWMAN NICHOLAS JOHN , MCDERMENT IAIN GRIERSON , CAMPBELL PATRICK JAMES
IPC分类号： B65D83/14 , G01F11/32
CPC分类号： B65D83/54 , G01F11/32
摘要： A valve mechanism is provided for use in an inhaler comprising a pressurised container, and a metering chamber, and a valve mechanism wherein the inlet and outlet valves are separate and can be operated independently. The pressure of the fluid in the canister is used to aid the opening of the outer valve so reducing the force to fire a dose. A variant of the valve mechanism allows the user to select from a range of dose volumes by appropriate orientation of the stem.
摘要翻译：提供用于包括加压容器和计量室的吸入器的阀机构，以及阀机构，其中入口阀和出口阀是分离的并且可以独立地操作。罐中的流体的压力用于帮助外部阀门的打开，从而减少喷射剂量的力。瓣膜机构的一个变体允许使用者通过杆的适当取向从一定范围的剂量体积中进行选择。

3. 发明申请

WO1998028033A2 INHALER DOSE COUNTER 审中-公开
标题翻译：吸入剂计数器
公开(公告)号：WO1998028033A2
公开(公告)日：1998-07-02
申请号：PCT/GB1997003480
申请日：1997-12-18
申请人： NORTON HEALTHCARE LIMITED , BOWMAN, Nicholas, John , HOLROYD, Michael, John , PANAYI, Costantinos , TRENEMAN, William, Richard
发明人： NORTON HEALTHCARE LIMITED
IPC分类号： A61M15/00
CPC分类号： A61M15/009 , A61M15/0068 , A61M15/0078 , G06M1/083 , G06M1/22 , G06M1/246
摘要： A dose counter for a metered dose inhaler comprises actuator means (341), drive means (350) for driving a rotary gear (360) in step-wise fashion in response to displacement of said actuator means (341), said rotary gear (360) comprising a wheel having a plurality of ratchet teeth (not shown) around its periphery. Means (364) are provided to prevent reverse rotation of the rotary gear (360). A flexible tape (368) is provided with a visible array of incrementing integers on its surface indicating the number of medicament doses remaining in the inhaler. The tape (368) indexes by a single integer in response to each step of the step-wise rotary motion of the rotary gear (360). A control surface (371) regulates the position of engagement and disengagement between the drive means (350) and the rotary gear (360). In an alternative embodiment (Figure 6), the control surface (371) is omitted and the means for preventing reverse rotation comprise a stepless restraint (664).
摘要翻译：用于计量剂量吸入器的剂量计数器包括致动器装置（341），用于响应于所述致动器装置（341）的位移而逐步地驱动旋转齿轮（360）的驱动装置（350），所述旋转齿轮（360））包括围绕其周边具有多个棘轮齿（未示出）的轮。提供装置（364）以防止旋转齿轮（360）的反向旋转。柔性带（368）在其表面上设置有可见的递增整数阵列，指示吸入器中剩余的药物剂量的数量。响应于旋转齿轮（360）的逐步旋转运动的每个步骤，带（368）由单个整数索引。控制表面（371）调节驱动装置（350）和旋转齿轮（360）之间的接合和分离的位置。在替代实施例（图6）中，省略了控制表面（371），并且防止反向旋转的装置包括无级限制（664）。

4. 发明申请

WO2009029029A1 INHALER FOR POWDERED SUBSTANCES WITH DESICCANT COMPARTMENT 审中-公开
标题翻译：用干燥剂容器填充粉末状物质
公开(公告)号：WO2009029029A1
公开(公告)日：2009-03-05
申请号：PCT/SE2008/050948
申请日：2008-08-22
申请人： ASTRAZENECA AB , BOWMAN, Nicholas John , GALE, David, Robert
发明人： BOWMAN, Nicholas John , GALE, David, Robert
IPC分类号： A61M15/00
CPC分类号： A61M15/0091 , A61M11/02 , A61M15/0015 , A61M15/0025 , A61M15/0065 , A61M15/0066 , A61M15/0093 , A61M15/0096 , A61M15/08 , A61M2202/062 , A61M2202/064 , A61M2205/073
摘要： The invention relates to an inhaler for powdered substance. The inhaler comprises an airflow passage for guiding substance towards an outlet, a substance storing chamber from which substance is provided to the airflow passage, a pressurizable space for establishing an air overpressure in the airflow passage for delivering substance present in the airflow passage to the outlet, a desiccant-containing compartment from which air is enabled to flow to the pressurizable space in order to replenish expelled air, and a filter provided in the desiccant-containing compartment, wherein air flowing from the desiccant- containing compartment to the pressurizable space passes through the filter.
摘要翻译：本发明涉及一种粉末状物质吸入器。吸入器包括用于将物质引向出口的气流通道，物质被供应到气流通道的物质存储室，用于在气流通道中建立空气超压的可加压空间，用于将存在于气流通道中的物质输送到出口，含有干燥剂的隔间，使得空气能够流动到可加压空间以补充排出的空气，以及设置在含干燥剂的隔室中的过滤器，其中从含干燥剂的隔间流入可加压空间的空气通过过滤器。

5. 发明申请

WO2004009471A3 INHALER VALVE MECHANISM 审中-公开
公开(公告)号：WO2004009471A3
公开(公告)日：2004-01-29
申请号：PCT/GB2003/003139
申请日：2003-07-18
申请人： THE TECHNOLOGY PARTNERSHIP PLC , GUTSELL, Graham, Scott , BOWMAN, Nicholas, John , McDERMENT, Iain, Grierson , CAMPBELL, Patrick, James
发明人： GUTSELL, Graham, Scott , BOWMAN, Nicholas, John , McDERMENT, Iain, Grierson , CAMPBELL, Patrick, James
IPC分类号： B65D83/14
摘要： A valve mechanism is provided for use in an inhaler comprising a pressurised container (11), and a metering chamber (15), and a valve mechanism wherein the inlet and outlet valves are separate and can be operated independently. The pressure of the fluid in the canister is used to aid the opening of the outer valve so reducing the force to fire a dose. A variant of the valve mechanism allows the user to select from a range of dose volumes by appropriate orientation of the stem.

6. 发明申请

WO9828033A3 Inhaler dose counter 审中-公开
标题翻译：吸入剂量计数器
公开(公告)号：WO9828033A3
公开(公告)日：1998-08-13
申请号：PCT/GB9703480
申请日：1997-12-18
申请人： NORTON HEALTHCARE LTD , BOWMAN NICHOLAS JOHN , HOLROYD MICHAEL JOHN , PANAYI CONTANTINOS , TRENEMAN WILLIAM RICHARD
发明人： BOWMAN NICHOLAS JOHN , HOLROYD MICHAEL JOHN , PANAYI CONSTANTINOS , TRENEMAN WILLIAM RICHARD
IPC分类号： A61M15/00 , G06M1/00 , G06M1/08 , G06M1/22 , G06M1/24
CPC分类号： A61M15/009 , A61M15/0068 , A61M15/0078 , G06M1/083 , G06M1/22 , G06M1/246
摘要： A dose counter for a metered dose inhaler comprises actuator means (341), drive means (350) for driving a rotary gear (360) in step-wise fashion in response to displacement of said actuator means (341), said rotary gear (360) comprising a wheel having a plurality of ratchet teeth (not shown) around its periphery. Means (364) are provided to prevent reverse rotation of the rotary gear (360). A flexible tape (368) is provided with a visible array of incrementing integers on its surface indicating the number of medicament doses remaining in the inhaler. The tape (368) indexes by a single integer in response to each step of the step-wise rotary motion of the rotary gear (360). A control surface (371) regulates the position of engagement and disengagement between the drive means (350) and the rotary gear (360). In an alternative embodiment (Figure 6), the control surface (371) is omitted and the means for preventing reverse rotation comprise a stepless restraint (664).

7. 发明申请

WO2011089534A3 DEVICE FOR DISPENSING A PLURALITY OF UNITARY DOSES OF DRY POWDER, AND INHALER COMPRISING SUCH DEVICE 审中-公开
标题翻译：用于分配大量单位干粉的装置，以及包含这种装置的吸入装置
公开(公告)号：WO2011089534A3
公开(公告)日：2011-10-27
申请号：PCT/IB2011050048
申请日：2011-01-06
申请人： PFIZER LTD , BOWMAN NICHOLAS JOHN , REILLY DECLAN
发明人： BOWMAN NICHOLAS JOHN , REILLY DECLAN
IPC分类号： A61M15/00
CPC分类号： A61M15/0045 , A47G2019/122 , A61M15/00 , A61M15/0028 , A61M15/0031 , A61M15/0048 , A61M15/0061 , A61M15/0068 , A61M2202/064 , B01F13/1058
摘要： Device for dispensing a plurality of unitary doses (2) of dry powder, comprising at least one support comprising conduits each defining a flow path for an airstream carrying one of the unitary dose (2), the support having first (26) and second (27) members secured to one another so that a first conduit portion (29) of the first member faces a second conduit portions (43) of the second member to define one of the conduits, and a first separation portion (30) of the first member faces a second separation portions (45) of the second member, the support comprising a plurality of barrier-forming elements (31, 46) each arranged between corresponding first (30) and second (45) separation portions to prevent dry powder from passing from one of the conduits to one of the adjacent conduits.
摘要翻译：用于分配多个单一剂量（2）的干粉末的装置，包括至少一个支撑件，其包括导管，每个管道限定用于携带单一剂量（2）中的一个的气流的流动路径，所述支撑件具有第一（26）和第二 27）构件彼此固定，使得第一构件的第一导管部分（29）面向第二构件的第二导管部分（43）以限定一个导管，并且第一构件的第一分隔部分（30）构件面对第二构件的第二分隔部分（45），所述支撑件包括多个阻挡形成元件（31,46），每个阻挡形成元件布置在相应的第一（30）和第二（45）分离部分之间，以防止干粉通过从一个导管到另一个相邻导管。

8. 发明申请

WO2009029028A1 BREATH- TRIGGERED INHALER WITH DOSE COUNTER 审中-公开
标题翻译： BREATH触发式吸入器与剂量计数器
公开(公告)号：WO2009029028A1
公开(公告)日：2009-03-05
申请号：PCT/SE2008/050947
申请日：2008-08-22
申请人： ASTRAZENECA AB , BOWMAN, Nicholas John , GALE, David, Robert , HUXHAM, Laurence Stanmore
发明人： BOWMAN, Nicholas John , GALE, David, Robert , HUXHAM, Laurence Stanmore
IPC分类号： A61M15/00
CPC分类号： A61M15/0091 , A61M11/02 , A61M15/0015 , A61M15/0025 , A61M15/0065 , A61M15/0066 , A61M15/0076 , A61M15/0093 , A61M15/0096 , A61M15/08 , A61M2202/064 , A61M2205/073
摘要： The invention relates to an inhaler for powdered substance. The inhaler comprises a transfer member which is displaceable in a substance storing chamber and which comprises at least one dosing chamber for taking up substance from the substance storing chamber and moving it to a flow passage. The transfer member, during its displacement, engages with a dose counter for advancing the number count. The dosing chamber is evacuated by an overpressure in the flow passage.
摘要翻译：本发明涉及一种粉末状物质吸入器。所述吸入器包括转移构件，所述转移构件可在物质储存室中移位，并且包括至少一个用于从所述物质储存室吸取物质并将其移动到流动通道的计量室。转移构件在其位移期间与剂量计数器接合以提高数量。剂量室通过流动通道中的过压排出。

9. 发明申请

WO2009029027A1 BREATH- TRIGGERED INHALER 审中-公开
标题翻译： BREATH TRIGGERED INHALER
公开(公告)号：WO2009029027A1
公开(公告)日：2009-03-05
申请号：PCT/SE2008/050946
申请日：2008-08-22
申请人： ASTRAZENECA AB , BOWMAN, Nicholas John , GALE, David, Robert
发明人： BOWMAN, Nicholas John , GALE, David, Robert
IPC分类号： A61M15/00
CPC分类号： A61M15/0091 , A61M11/02 , A61M15/0015 , A61M15/0025 , A61M15/0065 , A61M15/0066 , A61M15/0093 , A61M15/0096 , A61M15/08 , A61M2202/064 , A61M2205/073
摘要： The invention relates to an inhaler for powdered substance. The inhaler comprises a transfer member which is displaceable in a substance storing chamber and which comprises at least one dosing chamber for taking up substance from the substance storing chamber. The transfer member can being latched by an inhalation-triggered release mechanism which, upon inhalation by a user, unlatches the transfer member, thereby enabling it to move the dosing chamber to a flow passage.
摘要翻译：本发明涉及一种粉末状物质吸入器。吸入器包括可在物质储存室中移位的转移构件，该转移构件包括至少一个用于从物质储存室吸收物质的计量室。转移构件可以被吸入触发释放机构闩锁，该吸入触发释放机构在用户吸入时使转移构件脱落，从而使其能够将剂量室移动到流动通道。

10. 发明申请

WO2007007046A2 FORMING A HERMETIC SEAL ABOUT A CABLE 审中-公开
标题翻译：形成一个关于电缆的密封
公开(公告)号：WO2007007046A2
公开(公告)日：2007-01-18
申请号：PCT/GB2006/002493
申请日：2006-07-05
申请人： AQUAPAC INTERNATIONAL LIMITED , MACAULEY, Andrew, S. , COOKE, Charles, Brian, Durler , GROOMBRIDGE, Christopher, Benjamin, James , BOWMAN, Nicholas, John
发明人： MACAULEY, Andrew, S. , COOKE, Charles, Brian, Durler , GROOMBRIDGE, Christopher, Benjamin, James , BOWMAN, Nicholas, John
CPC分类号： H05K5/061 , H05K5/069 , Y10T24/15 , Y10T29/532
摘要： An housing for protecting a device from water damage, which is capable of being repeatedly opened and then hermetically sealed even when the device has a wire that must be extended outside of the apparatus. The housing has at least two members that, when juxtaposed and clamped, form a dry interior region. Each member includes a pair of gaskets that together define the dry interior region and substantially form a hermetic seal about a pouch or container. A portal is included through which the wire may extend from a device inside the pouch or container to the outside and a slide mechanism that adjust a gasket around the wire to maintain the dry interior region. The slide mechanism forms a hermetic seal around the wire so that the opening in the pouch from which the wire extends is hermetically sealed. If no wire is present, the slide mechanism may be adjusted to maintain the hermetic seal.
摘要翻译：一种用于保护设备免受水损害的壳体，即使当设备具有必须延伸到设备外部的导线时，其能够被重复地打开然后被密封。壳体至少有两个构件，当并置和夹紧时，形成干燥的内部区域。每个构件包括一对垫片，其一起限定干燥的内部区域并且基本上围绕袋或容器形成气密密封。包括入口，通过该入口，线可以从袋或容器内部的装置延伸到外部，以及滑动机构，其调节围绕线的垫圈以保持干燥的内部区域。滑动机构围绕电线形成气密密封，使得电线延伸的袋中的开口被气密地密封。如果不存在电线，则可以调节滑动机构以保持气密密封。

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