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1. 发明申请

WO2007088386A2 APPARATUS AND METHOD FOR DETECTING A DISCONTINUITY WITHIN A NON-BIOLOGICAL ELEMENT LOCATED WITHIN A BIOLOGICAL STRUCTURE 审中-公开
标题翻译：用于检测位于生物结构中的非生物元素之间的不连续性的装置和方法
公开(公告)号：WO2007088386A2
公开(公告)日：2007-08-09
申请号：PCT/GB2007000375
申请日：2007-02-05
申请人： HANCOCK CHRISTOPHER PAUL , BISHOP JOHN , BOOTON MARTIN WYNFORD
发明人： HANCOCK CHRISTOPHER PAUL , BISHOP JOHN , BOOTON MARTIN WYNFORD
IPC分类号： A61B5/05 , G01N22/00
CPC分类号： A61B5/05 , A61B5/0507 , A61B5/417
摘要： Apparatus for detecting a discontinuity within a non-biological element located within a biological structure, the apparatus comprising: a microwave energy source; a first antenna coupled to the microwave energy source and arranged to transmit the microwave energy into the biological structure; a second antenna arranged to receive at least a portion of the transmitted microwave energy; an antenna carrier arranged to have the first and second antenna affixed thereon and including means for moving the first and second antenna with respect to the biological structure; and a signal processing unit coupled to the second antenna and arranged to determine the phase and/or magnitude response of the received microwave energy as a function of the position of the antennas with respect to the biological structure and provide an indication of the location of the discontinuity within the non-biological element according to the phase and/or magnitude response.
摘要翻译：用于检测位于生物结构内的非生物元件内的不连续性的装置，所述装置包括：微波能量源; 耦合到所述微波能量源并被布置成将所述微波能量传输到所述生物结构中的第一天线; 布置成接收所传输的微波能量的至少一部分的第二天线; 天线载体布置成将第一和第二天线固定在其上并且包括用于相对于生物结构移动第一和第二天线的装置; 以及信号处理单元，其耦合到所述第二天线并且被布置成根据所述天线相对于所述生物结构的位置确定所接收的微波能量的相位和/或幅度响应，并且提供所述第二天线的位置的指示根据相位和/或幅度响应，非生物元件内的不连续性。

2. 发明申请

WO2007088386A3 APPARATUS AND METHOD FOR DETECTING A DISCONTINUITY WITHIN A NON-BIOLOGICAL ELEMENT LOCATED WITHIN A BIOLOGICAL STRUCTURE 审中-公开
公开(公告)号：WO2007088386A3
公开(公告)日：2007-08-09
申请号：PCT/GB2007/000375
申请日：2007-02-05
申请人： HANCOCK, Christopher, Paul , BISHOP, John , BOOTON, Martin, Wynford
发明人： HANCOCK, Christopher, Paul , BISHOP, John , BOOTON, Martin, Wynford
IPC分类号： A61B5/05 , G01N22/00
摘要： Apparatus for detecting a discontinuity within a non-biological element located within a biological structure, the apparatus comprising: a microwave energy source; a first antenna coupled to the microwave energy source and arranged to transmit the microwave energy into the biological structure; a second antenna arranged to receive at least a portion of the transmitted microwave energy; an antenna carrier arranged to have the first and second antenna affixed thereon and including means for moving the first and second antenna with respect to the biological structure; and a signal processing unit coupled to the second antenna and arranged to determine the phase and/or magnitude response of the received microwave energy as a function of the position of the antennas with respect to the biological structure and provide an indication of the location of the discontinuity within the non-biological element according to the phase and/or magnitude response.

3. 发明申请

WO2008110756A2 TISSUE CLASSIFYING APPARATUS 审中-公开
标题翻译：组织分类装置
公开(公告)号：WO2008110756A2
公开(公告)日：2008-09-18
申请号：PCT/GB2008/000762
申请日：2008-03-06
申请人： MEDICAL DEVICE INNOVATIONS LIMITED , HANCOCK, Christopher Paul , BISHOP, John , BOOTON, Martin Wynford
发明人： HANCOCK, Christopher Paul , BISHOP, John , BOOTON, Martin Wynford
IPC分类号： A61B18/18
CPC分类号： A61B18/18 , A61B5/05 , A61B5/0507 , A61B5/7264 , A61B18/1815
摘要： Tissue classifying apparatus in which forward microwave radiation (e.g. having a frequency 500 MHz to 60 GHz) is supplied from a source (108) along a first transmission path to a probe (116) which delivers it into tissue to be classified. The probe (116) receives reflected radiation from the tissue. The reflected radiation is delivered to a detector (178) along a second transmission path via a circulator (198) which isolates the forward radiation from the second transmission path. The detector has a input which is switchable between the reflected radiation from the second transmission path and a reference signal derived from the forward radiation, wherein detected magnitude and phase information of the reflected radiation to classify the tissue can be compensated for drift in magnitude and phase of the forward radiation by comparison with detected magnitude and phase information of the reference signal.
摘要翻译：其中将前向微波辐射（例如具有500MHz至60GHz的频率）从源（108）沿着第一传输路径提供给探测器（116）的组织分类设备将探测器（116）输送到要分类的组织中。探针（116）接收来自组织的反射辐射。反射的辐射经由环形器（198）沿着第二传输路径被传送到检测器（178），循环器将前向辐射与第二传输路径隔离。检测器具有可在来自第二传输路径的反射辐射和从正向辐射导出的参考信号之间切换的输入，其中检测到的用于分类组织的反射辐射的幅度和相位信息可被补偿在幅度和相位上的漂移与参考信号的检测到的幅度和相位信息进行比较。

4. 发明申请

WO2008043999A3 APPARATUS FOR TREATING TISSUE WITH MICROWAVE RADIATION AND ANTENNA CALIBRATION SYSTEM AND METHOD 审中-公开
标题翻译：用微波辐射和天线校准系统和方法处理组织的装置
公开(公告)号：WO2008043999A3
公开(公告)日：2008-07-17
申请号：PCT/GB2007003827
申请日：2007-10-10
申请人： MEDICAL DEVICE INNOVATIONS LTD , HANCOCK CHRISTOPHER PAUL , WHITE MALCOLM , BISHOP JOHN , BOOTON MARTIN WYNFORD
发明人： HANCOCK CHRISTOPHER PAUL , WHITE MALCOLM , BISHOP JOHN , BOOTON MARTIN WYNFORD
IPC分类号： A61N5/02 , A61B18/18
CPC分类号： A61B18/1815 , A61B5/0507 , A61B5/053 , A61B18/18 , A61B2017/00725 , A61B2018/00755 , A61B2018/00785 , A61B2018/00875 , A61B2018/1876 , A61N5/02
摘要： A calibration method and apparatus for surgical antennas which are arranged to deliver microwave radiation (e.g. having a treatment frequency of 500 MHz to 100 GHz) into biological tissue is disclosed. An emitting region of the antenna is exposed to a plurality of calibration standards each having a different complex impedance at the treatment frequency. In one embodiment the calibration standards are created in a short-circuit-terminated waveguide cavity of variable length. In another embodiment, each calibration standard is a different mixture of two or more liquids. Measurement of the magnitude and phase of signals reflected from the emitting region when exposed to the calibration standard can permit calibration of the antenna, e.g. by generating a mapping function based on the measured values and known or reference values for the calibration standards. Also disclosed is tissue treatment apparatus having an ablation channel for conveying microwave radiation to a surgical antenna at a high power level and a separate measurement channel for conveying microwave radiation to a surgical antenna at a low power level, wherein the measurement channel bypasses noisy components on the ablation channel. A surgical antenna having an impedance transformer for matching an e.g. coaxial feed structure which terminates in one or more radiating elements with tissue to be treated is also disclosed.
摘要翻译：公开了一种用于外科天线的校准方法和装置，其被布置为将微波辐射（例如具有500MHz至100GHz的治疗频率）递送到生物组织中。天线的发射区域暴露于在处理频率处具有不同复阻抗的多个校准标准。在一个实施例中，在可变长度的短路端接的波导腔中产生校准标准。在另一个实施方案中，每个校准标准是两种或更多种液体的不同混合物。当暴露于校准标准时，从发射区域反射的信号的幅度和相位的测量可以允许天线的校准，例如，通过基于测量值和校准标准的已知或参考值生成映射函数。还公开了一种组织处理设备，其具有用于将微波辐射传送到高功率水平的手术天线的消融通道和用于以低功率水平将微波辐射传送到手术天线的单独的测量通道，其中测量通道绕过噪声分量消融通道。具有阻抗变换器的手术天线，还公开了一种终止于一个或多个辐射元件与待处理组织的同轴馈送结构。

5. 发明申请

WO2012095653A1 ELECTROSURGICAL INSTRUMENT WITH DUAL RADIOFREQUENCY AND MICROWAVE ELECTROMAGNETIC ENERGY 审中-公开
标题翻译：具有双放射性和微波电磁能的静电仪
公开(公告)号：WO2012095653A1
公开(公告)日：2012-07-19
申请号：PCT/GB2012/050034
申请日：2012-01-09
申请人： CREO MEDICAL LIMITED , HANCOCK, Christopher Paul , BOOTON, Martin Wynford
发明人： HANCOCK, Christopher Paul , BOOTON, Martin Wynford
IPC分类号： H01Q1/38 , H01Q13/08 , A61B18/18
CPC分类号： A61B18/1815 , A61B2018/00202 , A61B2018/00571 , A61B2018/1876 , A61B2018/1892 , H01Q1/36 , H01Q13/08 , H01Q21/06
摘要： An electrosurgical instrument (402) for delivering radiofrequency (RF) electromagnetic (EM) energy and microwave frequency EM energy from a coaxial feed cable (406) through an instrument tip into tissue. The instrument tip comprises a dielectric body (416) separating first and second conductive elements, which act as active and return electrodes to convey the RF EM radiation by conduction, and as an antenna to radiate the microwave EM radiation. The instrument also has a fluid feed (424) incorporated into its tip, e.g. in an additional dielectric element (422) mounted on the underside of the tip, for delivering fluid. The delivered fluid may be a gas plasma to assist treatment or a liquid to plump up a tissue region before treatment. The instrument may fit in an endoscope.
摘要翻译：一种用于将同轴馈电电缆（406）的射频（RF）电磁（EM）能量和微波频率EM能量通过仪器尖端传送到组织中的电外科器械（402）。器械尖端包括分离第一和第二导电元件的电介质体（416），其作为有源和返回电极，以通过导电传送RF EM辐射，以及用作辐射微波EM辐射的天线。仪器还具有并入其尖端的流体进料（424），例如。在安装在尖端的下侧上的附加电介质元件（422）中，用于输送流体。输送的流体可以是气体等离子体，以在处理之前帮助治疗或液体丰满组织区域。仪器可以装在内窥镜中。

6. 发明申请

WO2008110756A3 TISSUE CLASSIFYING APPARATUS 审中-公开
标题翻译：组织分类装置
公开(公告)号：WO2008110756A3
公开(公告)日：2008-12-04
申请号：PCT/GB2008000762
申请日：2008-03-06
申请人： MEDICAL DEVICE INNOVATIONS LTD , HANCOCK CHRISTOPHER PAUL , BISHOP JOHN , BOOTON MARTIN WYNFORD
发明人： HANCOCK CHRISTOPHER PAUL , BISHOP JOHN , BOOTON MARTIN WYNFORD
IPC分类号： A61B18/18 , A61B5/05
CPC分类号： A61B18/18 , A61B5/05 , A61B5/0507 , A61B5/7264 , A61B18/1815
摘要： Tissue classifying apparatus in which forward microwave radiation (e.g. having a frequency 500 MHz to 60 GHz) is supplied from a source (108) along a first transmission path to a probe (116) which delivers it into tissue to be classified. The probe (116) receives reflected radiation from the tissue. The reflected radiation is delivered to a detector (178) along a second transmission path via a circulator (198) which isolates the forward radiation from the second transmission path. The detector has a input which is switchable between the reflected radiation from the second transmission path and a reference signal derived from the forward radiation, wherein detected magnitude and phase information of the reflected radiation to classify the tissue can be compensated for drift in magnitude and phase of the forward radiation by comparison with detected magnitude and phase information of the reference signal.
摘要翻译：其中正向微波辐射（例如具有500MHz至60GHz的频率）的辐射从第一传输路径上的源（108）提供给探针（116），该探针将其传送到待分类的组织中。探头（116）接收来自组织的反射辐射。反射的辐射通过循环器（198）沿着第二传输路径传送到检测器（178），该循环器将前向辐射与第二传输路径隔离。该检测器具有可在来自第二传输路径的反射辐射和从正向辐射导出的参考信号之间切换的输入，其中检测到的用于分类组织的反射辐射的幅度和相位信息可以补偿幅度和相位上的漂移通过与检测到的参考信号的幅度和相位信息进行比较来检测前向辐射。

7. 发明申请

WO2008043999A2 APPARATUS FOR TREATING TISSUE WITH MICROWAVE RADIATION AND ANTENNA CALIBRATION SYSTEM AND METHOD 审中-公开
标题翻译：用微波辐射处理组织的装置和天线校准系统和方法
公开(公告)号：WO2008043999A2
公开(公告)日：2008-04-17
申请号：PCT/GB2007/003827
申请日：2007-10-10
申请人： MEDICAL DEVICE INNOVATIONS LIMITED , HANCOCK, Christopher Paul , WHITE, Malcolm , BISHOP, John , BOOTON, Martin Wynford
发明人： HANCOCK, Christopher Paul , WHITE, Malcolm , BISHOP, John , BOOTON, Martin Wynford
IPC分类号： A61N5/02 , A61B18/18
CPC分类号： A61B18/1815 , A61B5/0507 , A61B5/053 , A61B18/18 , A61B2017/00725 , A61B2018/00755 , A61B2018/00785 , A61B2018/00875 , A61B2018/1876 , A61N5/02
摘要： A calibration method and apparatus for surgical antennas which are arranged to deliver microwave radiation (e.g. having a treatment frequency of 500 MHz to 100 GHz) into biological tissue is disclosed. An emitting region of the antenna is exposed to a plurality of calibration standards each having a different complex impedance at the treatment frequency. In one embodiment the calibration standards are created in a short-circuit-terminated waveguide cavity of variable length. In another embodiment, each calibration standard is a different mixture of two or more liquids. Measurement of the magnitude and phase of signals reflected from the emitting region when exposed to the calibration standard can permit calibration of the antenna, e.g. by generating a mapping function based on the measured values and known or reference values for the calibration standards. Also disclosed is tissue treatment apparatus having an ablation channel for conveying microwave radiation to a surgical antenna at a high power level and a separate measurement channel for conveying microwave radiation to a surgical antenna at a low power level, wherein the measurement channel bypasses noisy components on the ablation channel. A surgical antenna having an impedance transformer for matching an e.g. coaxial feed structure which terminates in one or more radiating elements with tissue to be treated is also disclosed.
摘要翻译：公开了一种用于外科手术天线的校准方法和装置，其被布置为将微波辐射（例如，具有500MHz到100GHz的治疗频率）递送到生物组织中。天线的发射区域暴露于多个校准标准，每个校准标准在处理频率处具有不同的复阻抗。在一个实施例中，校准标准在可变长度的短路终端波导腔中产生。在另一个实施例中，每个校准标准是两种或更多种液体的不同混合物。当暴露于校准标准时测量从发射区域反射的信号的幅度和相位可以允许天线的校准，例如，通过基于校准标准的测量值和已知或参考值生成映射函数。还公开了具有用于以高功率水平向手术天线传送微波辐射的消融通道和用于以低功率水平向手术天线传送微波辐射的单独测量通道的组织治疗设备，其中测量通道绕过噪声分量消融通道。一种具有阻抗变换器的手术天线，用于匹配例如，还公开了终止于一个或多个具有待处理组织的辐射元件的同轴馈送结构。

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