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1. 发明申请

WO2005102268A3 CHOLINESTERASE INHIBITORS IN LIPOSOMES AND THEIR PRODUCTION AND USE 审中-公开
标题翻译：在脂质体胆碱酯酶抑制剂及其制备方法和用途
公开(公告)号：WO2005102268A3
公开(公告)日：2006-04-06
申请号：PCT/AT2005000138
申请日：2005-04-21
申请人： SANOCHEMIA PHARMAZEUTIKA AG , BODENTEICH ANGELIKA , BOECKMANN JOSEF , FRANTSITS WERNER , PIRICH EBERHARD
发明人： BODENTEICH ANGELIKA , BOECKMANN JOSEF , FRANTSITS WERNER , PIRICH EBERHARD
IPC分类号： A61K9/127 , A61K9/00
CPC分类号： A61K9/127
摘要： The invention relates to a pharmaceutical composition based on an active ingredient that is enclosed in liposomes for topical, transdermal application. The interior of said liposomes comprises an acidic, aqueous medium containing at least one cholinesterase inhibitor, preferably from the group containing donepezil, rivastigmine, galantamine, physostigmine, heptylphysostigmine, phenserine, tolserine, cymserine, thiatolserine, thiacymserine, neostigmine, huperzine, tacrine, metrifonate and dichlorvos, or an enantiomer or derivative of at least one of said compounds. In addition, the invention relates to a method for producing said composition, optionally in a sterile form and also to the use of the liposomes charged with the active ingredient in various galenic formulations for topical, transdermal application with a depot effect in the epidermis, for the prophylaxis and/or treatment of cutaneous neuropathic pain or the loss of cutaneous sensory function as a result of neuropathy.
摘要翻译：本发明涉及一种用于局部，经皮应用的脂质体包埋的剂的基础上的药物组合物，其中所述脂质体具有在其内部的酸性含水环境和在至少一种胆碱酯酶抑制剂，优选选自多奈哌齐，利凡斯的明，加兰他敏，毒扁豆碱，heptylphysostigmine，phenserine，Tolserin，cymserine，Thiatolserin，Thiacymserin，新斯的明，石杉碱甲，他克林，美曲膦酯和敌敌畏，或其对映体或其衍生物，这些化合物中的至少一种。本发明还涉及一种方法，用于制备该组合物，任选以无菌形式，以及利用在用于与在表皮贮库效应局部透皮应用的各种盖伦制剂装载药物的脂质体，用于预防和/或治疗的皮肤神经性疼痛或皮肤感觉功能的neurophatiebedingten损失。

2. 发明申请

WO03098225A2 IN VITRO BIOASSAY FOR DETERMINING THE ACTIVITY OF GLYCOPROTEIN HORMONES 审中-公开
标题翻译：体外生物测定用于确定的糖蛋白激素的活动
公开(公告)号：WO03098225A2
公开(公告)日：2003-11-27
申请号：PCT/AT0300139
申请日：2003-05-15
申请人： ALVERTA U WERFFT AG , FRANTSITS J WERNER , BOECKMANN JOSEF , STOCKER WOLFGANG , SCHINKINGER MANFRED
发明人： FRANTSITS J WERNER , BOECKMANN JOSEF , STOCKER WOLFGANG , SCHINKINGER MANFRED
IPC分类号： C07K14/59 , G01N33/76
CPC分类号： C07K14/59 , G01N33/76
摘要： The invention relates to a simple and reliable method for determining the biological activity of hCG, whereby the progesterone response obtained by stimulation with hCG is evaluated in MA-10-cells.
摘要翻译：本发明涉及一种简单而可靠的方法，用于确定hCG的，通过与孕酮响应被用在MA-10细胞刺激实现的hCG的生物活性。

3. 发明申请

WO2012140214A1 IMMUNOAFFINITY SEPARATION MATERIALS COMPRISING ANTI-IgE ANTIBODY DERIVATIVES 审中-公开
标题翻译：包含抗IgE抗体衍生物的免疫分离物质
公开(公告)号：WO2012140214A1
公开(公告)日：2012-10-18
申请号：PCT/EP2012/056809
申请日：2012-04-13
申请人： BIOMAY AG , C4 Holding AG , HUBER, Hans , LUPINEK, Christian , MADEREGGER, Bernhard , STEGFELLNER, Gottfried , VALENTA, Rudolf , BOECKMANN, Josef , SCHALLENBERGER, Wolfgang , DORNER, Friedrich
发明人： HUBER, Hans , LUPINEK, Christian , MADEREGGER, Bernhard , STEGFELLNER, Gottfried , VALENTA, Rudolf , BOECKMANN, Josef , SCHALLENBERGER, Wolfgang , DORNER, Friedrich
IPC分类号： A61K39/395 , C07K16/42 , A61P37/00
CPC分类号： A61M1/3496 , C07K16/42 , C07K16/4291
摘要： The present invention provides an immunoaffinity separation material, comprising an antibody derivative having high specificity for soluble and cell bound IgE, an apheresis device comprising said material and its use for apheresis, specifically for plasmapheresis. It further provides a recombinant single chain antibody fragment with high specificity for soluble and cell bound IgE that is free of any tag sequences as well as the method for its production.
摘要翻译：本发明提供了一种免疫亲和分离材料，其包含对可溶性和细胞结合的IgE具有高特异性的抗体衍生物，包含所述材料的分离装置及其用于血浆置换术的专用血浆置换术。它进一步提供了对于不含任何标签序列的可溶性和细胞结合的IgE以及其生产方法具有高特异性的重组单链抗体片段。

4. 发明申请

WO2008119097A8 PHARMACEUTICAL SUBSTANCE FOR ITCHING AND PAIN 审中-公开
标题翻译：药物制剂对JUCKREIZ和PAIN
公开(公告)号：WO2008119097A8
公开(公告)日：2008-12-11
申请号：PCT/AT2008000120
申请日：2008-04-02
申请人： PLANTA NATURSTOFFE VERTRIEBSGE , KUBIN ANDREAS , BODENTEICH ANGELIKA , JESSNER GEORG , BOECKMANN JOSEF
发明人： KUBIN ANDREAS , BODENTEICH ANGELIKA , JESSNER GEORG , BOECKMANN JOSEF
IPC分类号： A61K36/537
CPC分类号： A61K36/537
摘要： The present invention relates to the use of Salvinorin or Salvia divinorum for producing a pharmaceutical composition for the topical treatment of itching or pain, a medication comprising the same, and the production thereof.
摘要翻译：本发明涉及salvinorin或Salvia divinorum在制备用于局部治疗瘙痒或疼痛的药物组合物中的用途，包含其的药物及其制备。

5. 发明申请

WO2008004127A3 METHOD FOR ADMINISTERING TOLPERISONE 审中-公开
标题翻译：治疗托哌酮的方法
公开(公告)号：WO2008004127A3
公开(公告)日：2008-05-08
申请号：PCT/IB2007002873
申请日：2007-04-20
申请人： SANOCHEMIA PHARMAZEUTIKA AG , BODENTEICH ANGELIKA , BOECKMANN JOSEF , FRANTSITS WERNER J
发明人： BODENTEICH ANGELIKA , BOECKMANN JOSEF , FRANTSITS WERNER J
IPC分类号： A61K31/4453 , A61P21/00 , A61P29/00
CPC分类号： A61K31/4453 , A61K9/2806 , A61K31/445
摘要： The present invention is directed to methods of administering tolperisone (2,4'-dimethyl- 3-piperidinopro?iophenone; 1-propanone, 2-methyl-1-(4-methylphenyl)-3-(-piperidinyl)), and kits comprising the same.
摘要翻译：本发明涉及给予托哌酮（2,4'-二甲基-3-哌啶子基二苯甲酮; 1-丙酮，2-甲基-1-（4-甲基苯基）-3 - （ - 哌啶基））的方法和试剂盒包括它们。

6. 发明申请

WO2006050544A3 TOLPERISON FOR TREATING DOGS HAVING DEGENERATIVE SPINAL SYMPTOMS 审中-公开
标题翻译：甲苯哌丙酮犬类退行性，脊髓症状的治疗
公开(公告)号：WO2006050544A3
公开(公告)日：2006-08-10
申请号：PCT/AT2005000382
申请日：2005-09-22
申请人： SANOCHEMIA PHARMAZEUTIKA AG , BODENTEICH ANGELIKA , FRANTSITS WERNER J , BOECKMANN JOSEF , VERNER ROBERT
发明人： BODENTEICH ANGELIKA , FRANTSITS WERNER J , BOECKMANN JOSEF , VERNER ROBERT
IPC分类号： A61K31/4453 , A61P19/00
CPC分类号： A61K31/4453
摘要： The invention relates to a veterinary medicinal preparation for oral administration for treating mammals such as dogs having degenerative spinal symptoms. This preparation contains, as an active ingredient, tolpersion together with at least one additive commonly used in veterinary medicine. A series of clinical signs in postoperative form or also during the preparation of possible surgical operations or during a long ongoing treatment carried out without possible surgical operations can be treated insofar as tolpersion is used as racemate in the form of its isomer mixture, in which the R(-) isomer is enriched in this mixture.
摘要翻译：本发明涉及用于在哺乳动物，治疗口服施用的兽医制剂，如狗与它们一起含有作为活性成分的Tolpersion与至少一种常用的添加剂，用于兽医学退行性脊柱症状。一些在手术后的形式或以任何手术的制备或在一个持久的疾病，而没有任何手术干预旨在治疗可以迄今被视为甲苯哌丙酮被用作在其异构体形式的外消旋物，其中所述R（ - ）异构体在该混合物中富集。

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