专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2022026423A1 IMMUNOGLOBULIN MEDIATED VACCINATIONS AGAINST VIRAL DISEASES 审中-公开
公开(公告)号：WO2022026423A1
公开(公告)日：2022-02-03
申请号：PCT/US2021/043243
申请日：2021-07-26
申请人： BLUTH, Martin, H.
发明人： BLUTH, Martin, H.
IPC分类号： A61K39/00 , A61K39/395 , A61P31/12 , C07K16/00 , C07K16/06 , C07K19/00
摘要： Techniques for inhibiting viral disease are provided. The techniques include obtaining a blood product from a convalescent patient, and administering the blood product to a patient at risk of contracting the same type of virus in order to propagate immunoglobulin-based vaccination.

2. 发明申请

WO2004071434A3 MONO, DI & TRI CYCLIC COMPOUNDS USEFUL FOR LOWERING IgE CONCENTRATIONS 审中-公开
标题翻译：用于降低IgE浓度的MONO，DI和TRI循环化合物
公开(公告)号：WO2004071434A3
公开(公告)日：2004-11-18
申请号：PCT/US2004003686
申请日：2004-02-09
申请人： DURKIN HELEN G , BLUTH MARTIN H , SMITH-NOROWITZ TAMAR A , JOKS RAUNO , KISELYOV ALEXANDER
发明人： DURKIN HELEN G , BLUTH MARTIN H , SMITH-NOROWITZ TAMAR A , JOKS RAUNO , KISELYOV ALEXANDER
IPC分类号： C07C49/835 , C07C225/20 , C07C237/24 , C07C49/76 , C07C233/00 , C07K16/00
CPC分类号： C07C49/835 , C07C225/20 , C07C237/24 , C07C2601/16 , C07C2602/28 , C07C2603/24
摘要： The present invention is directed novel compounds which are derivatives of minocycline or doxycycline, pharmaceutical compositions containing same and use thereof in lowering excess IgE levels in a mammal suffering from a disease where IgE is pathogenic.
摘要翻译：本发明涉及米诺环素或多西环素衍生物的新化合物，含有它的药物组合物及其用于降低患有IgE致病性疾病的哺乳动物的过量IgE水平的用途。

3. 发明申请

WO2004071434A2 MONO, DI & TRI CYCLIC COMPOUNDS USEFUL FOR LOWERING IgE CONCENTRATIONS 审中-公开
标题翻译： MONO，DI和TRI循环化合物有助于降低IgE浓度
公开(公告)号：WO2004071434A2
公开(公告)日：2004-08-26
申请号：PCT/US2004/003686
申请日：2004-02-09
申请人： DURKIN, Helen, G. , BLUTH, Martin, H. , SMITH-NOROWITZ, Tamar, A. , JOKS, Rauno , KISELYOV, Alexander
发明人： DURKIN, Helen, G. , BLUTH, Martin, H. , SMITH-NOROWITZ, Tamar, A. , JOKS, Rauno , KISELYOV, Alexander
IPC分类号： A61K
CPC分类号： C07C49/835 , C07C225/20 , C07C237/24 , C07C2601/16 , C07C2602/28 , C07C2603/24
摘要： The present invention is directed novel compounds which are derivatives of minocycline or doxycycline, pharmaceutical compositions containing same and use thereof in lowering excess IgE levels in a mammal suffering from a disease where IgE is pathogenic.
摘要翻译：本发明涉及作为二甲胺四环素或多西环素的衍生物的新型化合物，含有它们的药物组合物及其在降低IgE致病性疾病的哺乳动物中降低过量IgE水平的用途。

4. 发明申请

WO2004014434A1 A METHOD FOR MONITORING THE EFFECTIVENESS OF TETRACYCLINE IN THE TREATMENT OF ASTHMA 审中-公开
标题翻译：监测四氯化碳在治疗哮喘中的有效性的方法
公开(公告)号：WO2004014434A1
公开(公告)日：2004-02-19
申请号：PCT/US2003/024746
申请日：2003-08-08
申请人： DURKIN, Helen, G. , JOKS, Rauno , SMITH-NOROWITZ, Tamar, A. , BLUTH, Martin, H.
发明人： DURKIN, Helen, G. , JOKS, Rauno , SMITH-NOROWITZ, Tamar, A. , BLUTH, Martin, H.
IPC分类号： A61K49/00
CPC分类号： G01N33/6854 , A61K31/65 , G01N2800/122 , G01N2800/52 , A61K2300/00
摘要： The present invention is directed to a method of lowering excess IgE levels in a mammal suffering from a disease where IgE is pathogenic which method comprises administering to said mammal an IgE lowering effective amount of a tetracycline such as minocycline or doxycline. It is also directed to a method of monitoring the effectiveness of a drug in lowering the concentration of excess IgE in the plasma in a mammal suffering from the disease in which IgE is pathogenic which method comprises making a first determination of the concentration of IgE in the plasma of said mammal at an initial time; administering to said mammal the drug; making a second determination of the concentration of IgE in the plasma of said mammal after the initial time and after administration of the drug and comparing the values obtained from the first and second determinations, such that if the value of the second determination is higher than or about the same as the value of the first determination and above a threshold level, then the dosage amount of the drug administered to the mammal is increased; otherwise the dosage amount is maintained.
摘要翻译：本发明涉及一种降低患有IgE致病性疾病的哺乳动物中过量IgE水平的方法，该方法包括向所述哺乳动物施用降低有效量的四环素如米诺环素或多西环素的IgE。还涉及一种监测药物在降低IgE致病性疾病的哺乳动物血浆中过量IgE浓度的有效性的方法，该方法包括首先测定IgE的浓度所述哺乳动物在初始时的血浆; 向所述哺乳动物施用所述药物; 在所述哺乳动物的初始时间和给药后第二次测定所述哺乳动物血浆中IgE的浓度，并比较从第一次和第二次测定获得的值，使得如果第二次测定的值高于或与第一次测定的值相同且高于阈值水平，则给予哺乳动物的药物的给药量增加; 否则维持剂量。

5. 发明申请

WO2004098391A3 METHODS FOR DETECTING PARVOVIROUS INFECTIONS 审中-公开
标题翻译：检测寄生虫感染的方法
公开(公告)号：WO2004098391A3
公开(公告)日：2006-03-09
申请号：PCT/US2004014012
申请日：2004-05-05
申请人： SMITH-NOROWITZ TAMAR , NOROWITZ KEVIN D , BLUTH MARTIN H , DURKIN HELEN G
发明人： SMITH-NOROWITZ TAMAR , NOROWITZ KEVIN D , BLUTH MARTIN H , DURKIN HELEN G
IPC分类号： C12Q1/70 , A61B20060101 , G01N33/569
CPC分类号： G01N33/56983 , G01N2333/015 , G01N2469/20
摘要： The present invention provides a method for diagnosing a subject suffering a pathological condition characterized by parvovirus infection by detecting the presence of IgE anti-Parvovirus B 19 antibodies.
摘要翻译：本发明提供一种用于通过检测IgE抗细小病毒B19抗体的存在来诊断患有细小病毒感染特征性病理状况的受试者的方法。

6. 发明申请

WO2004098391A2 METHODS FOR DETECTING PARVOVIROUS INFECTIONS 审中-公开
标题翻译：检测寄生虫感染的方法
公开(公告)号：WO2004098391A2
公开(公告)日：2004-11-18
申请号：PCT/US2004/014012
申请日：2004-05-05
申请人： SMITH-NOROWITZ, Tamar , NOROWITZ, Kevin, D. , BLUTH, Martin, H. , DURKIN, Helen, G.
发明人： SMITH-NOROWITZ, Tamar , NOROWITZ, Kevin, D. , BLUTH, Martin, H. , DURKIN, Helen, G.
IPC分类号： A61B
CPC分类号： G01N33/56983 , G01N2333/015 , G01N2469/20
摘要： The present invention provides a method for diagnosing a subject suffering a pathological condition characterized by parvovirus infection by detecting the presence of IgE anti-Parvovirus B 19 antibodies.
摘要翻译：本发明提供一种用于通过检测IgE抗细小病毒B19抗体的存在来诊断患有细小病毒感染特征性病理状况的受试者的方法。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式