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1. 发明申请

WO2017100685A1 METHODS AND APPARATUS FOR MEASURING BLOOD OXYGENATION OF TISSUE 审中-公开
标题翻译：用于测量组织血液氧化的方法和设备
公开(公告)号：WO2017100685A1
公开(公告)日：2017-06-15
申请号：PCT/US2016/065990
申请日：2016-12-09
申请人： BIOXYTECH RETINA, INC.
发明人： BASIRI, Ali
IPC分类号： A61B5/00 , A61B5/1455
CPC分类号： A61B5/7257 , A61B5/14552 , A61B5/14555
摘要： An apparatus and method of measuring oxygenation of tissue in a non-invasive manner are provided. The apparatus comprises a light source configured to emit a light pattern to be projected onto the tissue, in which the light pattern comprises superimposed patterns having different patterns. A detector captures an image of a reflected light pattern which is reflected from the tissue as a result of the projected light pattern. A processor coupled to the detector can be configured to perform a transform on the image of the reflected light pattern and determine oxygenation of each of a plurality of layers of the tissue in response to the transform of the image. Polarimetry can be used in determining a change in polarization angle of light beam. Tissue oxygenation can be determined at a plurality of layers from one snapshot, for example oxygenation of retinal layers.
摘要翻译：提供了一种以非侵入方式测量组织氧合的装置和方法。该装置包括光源，该光源配置成发射待投影到组织上的光图案，其中光图案包括具有不同图案的叠加图案。作为投影光图案的结果，检测器捕获从组织反射的反射光图案的图像。耦合到检测器的处理器可以被配置为对反射光图案的图像执行变换并且响应于图像的变换来确定组织的多个层中的每个层的充氧。偏振测定可用于确定光束偏振角的变化。组织氧合可以在一次快照的多个层处确定，例如视网膜层的氧合。

2. 发明申请

WO2022147164A1 METHODS AND DEVICES FOR MEASURING STRUCTURAL AND FUNCTIONAL PROPERTIES OF TISSUE 审中-公开
公开(公告)号：WO2022147164A1
公开(公告)日：2022-07-07
申请号：PCT/US2021/065563
申请日：2021-12-29
申请人： BIOXYTECH RETINA, INC.
发明人： BASIRI, Ali
IPC分类号： A61B5/00 , A61B5/1455 , A61B5/02 , A61B5/0245 , G06T7/00
摘要： A method of determining a parameter related to a blood oxygenation of tissue may include projecting an optical pattern onto the tissue, the optical pattern comprising a spatially varying component in at least one axis. A method of determining a parameter related to a blood oxygenation of tissue may include collecting a reflected optical signal from at least a first and a second wavelength range, wherein the first and the second wavelength ranges are distinct. A method of determining a parameter related to a blood oxygenation of tissue may include normalizing the reflected optical signal. A method of determining a parameter related to a blood oxygenation of tissue may include performing a transform of the reflected optical signal. A method of determining a parameter related to a blood oxygenation of tissue may include determining the parameter related to the blood oxygenation of the tissue based on the ratio and the transform.

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