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1. 发明申请

WO2004091842A1 VERFAHREN ZUR HERSTELLUNG VON MEHRSCHICHTSYSTEMEN 审中-公开
标题翻译：用于生产组合系统
公开(公告)号：WO2004091842A1
公开(公告)日：2004-10-28
申请号：PCT/DE2004/000732
申请日：2004-04-07
申请人： LPKF LASER & ELECTRONICS AG , ROCHE DIAGNOSTICS GMBH , MEIER, Dieter , SINGH BHULLAR, Raghbir
发明人： MEIER, Dieter , SINGH BHULLAR, Raghbir
IPC分类号： B23K26/18
CPC分类号： H01L51/0016 , B23K26/40 , B23K2203/08 , B23K2203/10 , B23K2203/12 , B23K2203/172 , B23K2203/26 , B23K2203/42 , B23K2203/50 , C23C14/5813 , C23C14/5873 , C23C16/56 , H01L51/0002 , H01L51/001 , H01L51/0021
摘要： Die Erfindung betrifft ein Verfahren zur Herstellung von Mehrschichtsystemen auf einem nicht leitenden Substrat (11), bei dem im Wechsel metallische Schichten (12, 16) mittels PVD-Technik und elektrisch nicht leitende Schichten (14) mittels PECVD-Technik abgeschieden und so modifiziert werden, dass die wahlweise selektive Strukturierung einer oder mehrerer Schichten möglich wird Dabei wurde festgestellt, dass nur durch Einführung von „Opferschichten“ (13, 15) eine selektive Strukturierung durch Laserenergie möglich ist. Hierdurch wird erstmals eine Miniaturisierung erreicht, die mit konventionell aufgebauten Mehrschichtsystemen nicht realisierbar ist.
摘要翻译：本发明涉及一种用于生产非导电衬底（11）上的多层系统，其中金属交替层（12，16）通过PVD技术的装置，并且非导电层（14）通过PECVD技术淀积和改性该一个或多个层的任选的选择性构图可能仅此情况下通过引入“牺牲层”（13，15）的被检测到，一个选择性构图由激光能量是可能的。这使得小型化第一实现，这是不可能与现有结构的多层系统。

2. 发明申请

WO2005066616A2 BIOSENSOR AND METHOD OF MAKING CROSS-REFERENCE TO RELATED APPLICATIONS 审中-公开
标题翻译：生物传感器及其制造方法相关申请的交叉引用
公开(公告)号：WO2005066616A2
公开(公告)日：2005-07-21
申请号：PCT/US2004/019553
申请日：2004-06-18
申请人： ROCHE DIAGNOSTICS GMBH , F.HOFFMAN LA ROCHE AG , BHULLAR, Raghbir, S. , DIEBOLD, Eric, R. , HILL, Brian, S. , SURRIDGE, Nigel , WALLING, Paul, Douglas
发明人： BHULLAR, Raghbir, S. , DIEBOLD, Eric, R. , HILL, Brian, S. , SURRIDGE, Nigel , WALLING, Paul, Douglas
IPC分类号： G01N27/30
CPC分类号： G01N33/5438 , C12Q1/001 , G01N27/3272 , H05K1/0393 , H05K3/027 , Y10T29/49007 , Y10T29/49117 , Y10T29/49155 , Y10T29/49156
摘要： An electrochemical biosensor with electrode elements that possess smooth, highquality edges. These smooth edges define gaps between electrodes, electrode traces and contact pads. Due to the remarkable edge smoothness achieved with the present invention, the gaps can be quite small, which provides marked advantages in terms of test accuracy, speed and the number of different functionalities that can be packed into a single biosensor. Further, the present invention provides a novel biosensor production method in which entire electrode patterns for the inventive biosensors can be formed all at one, in nanoseconds -- without regard to the complexity of the electrode patterns or the amount of conductive material that must be ablated to form them.
摘要翻译：具有电极元件的电化学生物传感器具有光滑，高品质的边缘。这些光滑边缘限定电极，电极迹线和接触垫之间的间隙。由于本发明实现了显着的边缘平滑度，所以间隙可以相当小，这在测试精度，速度和可以包装到单个生物传感器中的不同功能的数量方面提供显着的优点。此外，本发明提供了一种新颖的生物传感器制造方法，其中可以以纳秒为单位形成本发明生物传感器的整个电极图案，而不考虑电极图案的复杂性或必须消融的导电材料的量形成它们。

3. 发明申请

WO2005012900A1 BIOSENSOR WITH MULTIPLE ELECTRICAL FUNCTIONALITIES 审中-公开
标题翻译：具有多种电气功能的生物传感器
公开(公告)号：WO2005012900A1
公开(公告)日：2005-02-10
申请号：PCT/US2004/019652
申请日：2004-06-18
申请人： ROCHE DIAGNOSTICS GMBH , F. HOFFMAN-LA ROCHE AG , BHULLAR, Raghbir, S. , BUCK, Harvey, B. , HILL, Brian, S. , WALLING, Paul, Douglas , BEATY, Terry, A. , BURKE, David, W. , DIEBOLD, Eric, R.
发明人： BHULLAR, Raghbir, S. , BUCK, Harvey, B. , HILL, Brian, S. , WALLING, Paul, Douglas , BEATY, Terry, A. , BURKE, David, W. , DIEBOLD, Eric, R.
IPC分类号： G01N33/487
CPC分类号： C12M1/00 , C12Q1/001 , G01N27/3272
摘要： A biosensor having multiple electrical functionalities located both within and outside of the measurement zone in which a fluid sample is interrogated. Incredibly small and complex electrical patterns with high quality edges provide electrical functionalities in the biosensor and also provide the electrical wiring for the various other electrical devices provided in the inventive biosensor. In addition to a measurement zone with multiple and various electrical functionalities, biosensors of the present invention may be provided with a user interface zone, a digital device zone and/or a power generation zone. The inventive biosensors offer improved ease of use and performance, and decrease the computational burden and associated cost of the instruments that read the biosensors by adding accurate yet cost-effective functionalities to the biosensors themselves.
摘要翻译：具有位于测量区域内和外部的多个电功能的生物传感器，其中询问流体样品。具有高质量边缘的难以置信的小且复杂的电气图案在生物传感器中提供电功能，并且还为本发明的生物传感器中提供的各种其它电气装置提供电线。除了具有多个和各种电功能的测量区域之外，本发明的生物传感器可以设置有用户界面区域，数字设备区域和/或发电区域。本发明的生物传感器提供了改进的易用性和性能，并且通过向生物传感器本身添加准确而成本有效的功能来降低读取生物传感器的仪器的计算负担和相关成本。

4. 发明申请

WO2005066616A3 BIOSENSOR AND METHOD OF MAKING CROSS-REFERENCE TO RELATED APPLICATIONS 审中-公开
标题翻译：生物传感器及其制造方法相关申请的交叉引用
公开(公告)号：WO2005066616A3
公开(公告)日：2005-11-10
申请号：PCT/US2004019553
申请日：2004-06-18
申请人： ROCHE DIAGNOSTICS GMBH , HOFFMANN LA ROCHE , BHULLAR RAGHBIR S , DIEBOLD ERIC R , HILL BRIAN S , SURRIDGE NIGEL , WALLING PAUL DOUGLAS
发明人： BHULLAR RAGHBIR S , DIEBOLD ERIC R , HILL BRIAN S , SURRIDGE NIGEL , WALLING PAUL DOUGLAS
IPC分类号： B23K26/36 , C12Q1/00 , G01N27/30 , G01N27/403 , G01N33/487 , G01N33/49 , G01N33/543 , H05K1/00 , H05K3/02
CPC分类号： G01N33/5438 , C12Q1/001 , G01N27/3272 , H05K1/0393 , H05K3/027 , Y10T29/49007 , Y10T29/49117 , Y10T29/49155 , Y10T29/49156
摘要： An electrochemical biosensor (210) with electrode elements (274, 276) that possess smooth, high-quality edges (281, 283, 285, 287) with an edge definition better than 6µm. These smooth edges define gaps between electrodes, electrode traces and contact pads. Due to the remarkable edge smoothness achieved, the gaps can be quite small, which provides marked advantages in terms of test accuracy, speed and the number of different functionalities that can be packed into a single biosensor. Further, the present application provides a biosensor production method in which entire electrode patterns for the inventive biosensors can be formed all at one, in nanoseconds - without regard to the complexity of the electrode patterns or the amount of conductive material that must be ablated to form them.
摘要翻译：具有电极元件（274,276）的电化学生物传感器（210）具有平滑，高质量的边缘（281,283,285,287），边缘清晰度优于6μm。这些光滑边缘限定电极，电极迹线和接触垫之间的间隙。由于实现了明显的边缘平滑度，间隙可以相当小，这在测试精度，速度和可以包装在单个生物传感器中的不同功能的数量方面提供了显着的优势。此外，本申请提供了一种生物传感器制造方法，其中可以以纳秒为单位形成本发明生物传感器的整个电极图案，而不考虑电极图案的复杂性或必须烧蚀形成的导电材料的量他们。

5. 发明申请

WO2004113900A2 TEST STRIP WITH FLARED SAMPLE RECEIVING CHAMBER 审中-公开
标题翻译：带有采样样品的测试条
公开(公告)号：WO2004113900A2
公开(公告)日：2004-12-29
申请号：PCT/US2004/019684
申请日：2004-06-18
申请人： ROCHE DIAGNOSTICS GMBH , F. HOFFMANN-LA ROCHE AG , BHULLAR, Raghbir, Singh , SURRIDGE, Nigel, A. , FUNKE, Tom , RIGGLES, Randall, K. , WALLING, Paul, Douglas
发明人： BHULLAR, Raghbir, Singh , SURRIDGE, Nigel, A. , FUNKE, Tom , RIGGLES, Randall, K. , WALLING, Paul, Douglas
IPC分类号： G01N27/30
CPC分类号： G01N33/558 , G01N27/3271 , Y10T156/1059 , Y10T156/1084
摘要： A test strip with a sample receiving chamber having a novel flared portion that terminates in a sample receiving opening. The flared portion provides a reservoir from which sample fluid can be drawn into the capillary or sample receiving chamber. The wider opening provided by the present invention is easier to "target" with a sample fluid. In preferred embodiments, the hydrophilic reagent layer extends to the dosing end or side of the test strip and further promotes wicking of the sample into the sample receiving chamber and thus reduces dose hesitation. In other preferred embodiments, a tapered dosing end is provided on the test strip in combination with the flared portion, and this combination create a test strip that will draw sample fluid into the sample receiving chamber regardless of where along the dosing edge of the test strip the fluid sample makes contact.
摘要翻译：具有样品接收室的测试条具有终止于样品接收开口的新颖的扩口部分。扩口部分提供储存器，样品流体可从该储存器吸入毛细管或样品接收室。本发明提供的更宽的开口更容易用样品流体“目标”。在优选的实施方案中，亲水试剂层延伸到测试条的计量端或侧，并进一步促进样品的芯吸到样品接收室中，从而减少剂量犹豫。在其它优选实施例中，在测试条上与锥形部分结合地提供锥形剂量端，并且该组合产生测试条，其将样品流体吸入样品接收室，而不管沿着测试条的计量边缘的哪里流体样品接触。

6. 发明申请

WO2011038496A1 PROCESS FOR REFURBISHING CYLINDER ROLLS AND BASES FOR PRINTING MACHINES 审中-公开
标题翻译：翻新圆筒滚筒和打印机基座的工艺
公开(公告)号：WO2011038496A1
公开(公告)日：2011-04-07
申请号：PCT/CA2010/001543
申请日：2010-09-29
申请人： GARRY MACHINE MFG. INC. , BHULLAR, Raghbir , PADHYE, Nitin , CAMPBELL, David, R.
发明人： BHULLAR, Raghbir , PADHYE, Nitin , CAMPBELL, David, R.
IPC分类号： B41C1/18 , B41N1/20
CPC分类号： B41F13/11 , B41C1/18 , B41N1/20 , B41N3/003 , B41N7/005 , B41N2207/02 , B41N2207/04 , B41N2207/14 , Y10T29/49545 , Y10T29/4956 , Y10T29/49563
摘要： The present invention relates to a refurbished cylinder roller and a process for refurbishing cylinder rollers for use in printing machines. More particularly, the present invention also relates to a process for refurbishing metallic gravure cylinder rollers by replacing the worn outer plating layers with an extruded and thermally cured electrically conductive polymer material, and thereafter electroplating new outer plating layers thereon, the new plating layers including a new printing image formed therein. The present invention also relates to a refurbished gravure cylinder roller which includes a core member extending along an axial length, an image-carrying layer having a printing image formed therein and arranged circumferentially about the core member, and an electrically conductive intermediate polymer layer arranged between the core member and the image-carrying layer, where the intermediate polymer material has a conductivity selected to permit electro¬ plating of the image-carrying layer directly thereon.
摘要翻译：本发明涉及一种翻新的圆筒滚子和用于翻新用于印刷机的滚筒滚筒的方法。更具体地说，本发明还涉及一种通过用挤出和热固化的导电聚合物材料替换磨损的外镀层，然后在其上电镀新的外镀层来翻新金属凹版滚筒辊的方法，所述新镀层包括在其中形成新的印刷图像。本发明还涉及一种翻新的凹版滚筒辊，其包括沿轴向长度延伸的芯部件，具有形成在其中并且围绕芯部件周向布置的印刷图像的图像承载层，以及布置在芯构件和图像承载层，其中中间聚合物材料具有选择的导电性，以允许图像承载层直接在其上电镀。

7. 发明申请

WO2009056299A1 ELECTRICAL PATTERNS FOR BIOSENSOR AND METHOD OF MAKING 审中-公开
标题翻译：生物传感器的电气模式及其制作方法
公开(公告)号：WO2009056299A1
公开(公告)日：2009-05-07
申请号：PCT/EP2008/009143
申请日：2008-10-29
申请人： ROCHE DIAGNOSTICS GMBH , F. HOFFMANN-LA ROCHE AG , BHULLAR, Raghbir, Sing , CELENTANO, Mike , EL-RAHAIBY, Said, K.
发明人： BHULLAR, Raghbir, Sing , CELENTANO, Mike , EL-RAHAIBY, Said, K.
IPC分类号： C12Q1/00 , G01N27/30 , G01N33/487
CPC分类号： G01N27/3277 , G01N27/3272 , G01N33/5438
摘要： The present invention provides an inventive biosensor that includes multiple regions in which the electrical pattern is formed from different electrically conductive materials. The present invention also provides an inventive method for mass producing biosensors as just described. In one embodiment of this method, first and second different electrically conductive materials are deposited side by side on a portion of an electrically insulating base material, and a plurality of electrical patterns is formed on the portion of the base material. Each electrical pattern includes a first region formed from the first electrically conductive material electrically connected to a second region formed from the second electrically conductive material. The electrically conductive materials can be deposited as layers on the base material and portions of the layers can be removed to form the electrical patterns, or, the electrical patterns can be formed by transferring the conductive material in the shape of the electrical pattern directly to the base material, such as by a laser direct transfer technique.
摘要翻译：本发明提供了本发明的生物传感器，其包括多个区域，其中电图案由不同的导电材料形成。本发明还提供了如上所述的用于批量生产生物传感器的发明方法。在该方法的一个实施例中，第一和第二不同的导电材料并排地沉积在电绝缘基材的一部分上，并且在基材的部分上形成多个电图案。每个电图案包括由第一导电材料形成的第一区域，电连接到由第二导电材料形成的第二区域。导电材料可以作为层沉积在基底材料上，并且可以去除这些层的部分以形成电图案，或者可以通过将电图案形状的导电材料直接转移到基材，例如通过激光直接转印技术。

8. 发明申请

WO2004113900A3 TEST STRIP WITH FLARED SAMPLE RECEIVING CHAMBER 审中-公开
公开(公告)号：WO2004113900A3
公开(公告)日：2004-12-29
申请号：PCT/US2004/019684
申请日：2004-06-18
申请人： ROCHE DIAGNOSTICS GMBH , F. HOFFMANN-LA ROCHE AG , BHULLAR, Raghbir, Singh , SURRIDGE, Nigel, A. , FUNKE, Tom , RIGGLES, Randall, K. , WALLING, Paul, Douglas
发明人： BHULLAR, Raghbir, Singh , SURRIDGE, Nigel, A. , FUNKE, Tom , RIGGLES, Randall, K. , WALLING, Paul, Douglas
IPC分类号： G01N27/30
摘要： A test strip with a sample receiving chamber having a novel flared portion that terminates in a sample receiving opening. The flared portion provides a reservoir from which sample fluid can be drawn into the capillary or sample receiving chamber. The wider opening provided by the present invention is easier to "target" with a sample fluid. In preferred embodiments, the hydrophilic reagent layer extends to the dosing end or side of the test strip and further promotes wicking of the sample into the sample receiving chamber and thus reduces dose hesitation. In other preferred embodiments, a tapered dosing end is provided on the test strip in combination with the flared portion, and this combination create a test strip that will draw sample fluid into the sample receiving chamber regardless of where along the dosing edge of the test strip the fluid sample makes contact.

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