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1. 发明申请

WO2007113494A1 METHOD OF PRODUCING A MULTI-LAYER SELF-SEALING GRAFT 审中-公开
标题翻译：生产多层自密封格栅的方法
公开(公告)号：WO2007113494A1
公开(公告)日：2007-10-11
申请号：PCT/GB2007/001146
申请日：2007-03-28
申请人： VASCUTEK LIMITED , ASHTON, Timothy, Rawden , DUNLOP, Craig
发明人： ASHTON, Timothy, Rawden , DUNLOP, Craig
IPC分类号： A61F2/06
CPC分类号： A61F2/06 , B29C45/14598 , B29K2021/00 , B29K2025/00 , B29K2027/18 , B29K2221/003 , B29L2009/00 , B29L2023/007 , B29L2031/7534 , B32B1/08 , B32B3/263 , B32B27/08 , B32B27/22 , B32B27/302 , B32B27/322 , B32B27/40 , B32B2274/00 , B32B2535/00
摘要： There is provided a method of forming a multi-layer self-sealing graft, in which the method comprises providing a tubular structure located within a cavity suitable for injection moulding, introducing a thermoplastic elastomer in liquid form into a gap located between the tubular structure and the cavity and allowing the thermoplastic elastomer to solidify. Additionally, an outer layer is located on top of the thermoplastic elastomer to give a sandwich construction. The tubular structure is preferably formed from ePTFE and the thermoplastic elastomer is preferably polyurethane or a styrene block copolymer.
摘要翻译：提供了形成多层自密封移植物的方法，其中所述方法包括提供位于适于注射成型的腔内的管状结构，将液体形式的热塑性弹性体引入位于管状结构和并使热塑性弹性体固化。此外，外层位于热塑性弹性体的顶部，得到夹层结构。管状结构优选由ePTFE形成，并且热塑性弹性体优选为聚氨酯或苯乙烯嵌段共聚物。

2. 发明申请

WO1992010532A1 FLUORINATING POLYMER SURFACES 审中-公开
标题翻译：荧光聚合物表面
公开(公告)号：WO1992010532A1
公开(公告)日：1992-06-25
申请号：PCT/GB1991002180
申请日：1991-12-09
申请人： VASCUTEK LIMITED , PATON, Duncan, McMillan , ASHTON, Timothy, Rawden , MAINI, Roshan
发明人： VASCUTEK LIMITED
IPC分类号： C08J07/04
CPC分类号： C08J3/091 , A61L33/0082 , A61L33/064 , B05D7/02 , B05D2201/02 , B05D2401/10 , B05D2506/10 , C08J7/047 , C08J2327/12 , C08J2427/00 , D06M15/256 , D06M23/10 , D06M2101/32 , A61F2/06 , C08L27/18 , C08L27/12
摘要： Surfaces of polymers, particularly polyesters, can be fluorinated by deposition of a fluorocarbon from solution. The fluorocarbon may be an amorphous fluoropolymer, such as the copolymer of tetrafluoroethylene and bis-2,2-trifluoromethyl-4,5-difluoro-1,2-dioxole sold under the trademark TEFLON AF , which is soluble in fluorinated alkanes and other fluorinated liquids such as those sold under the trademark FLUORINERT . Surface-fluorinated polyesters, particularly in knitted fabric form, are useful as vascular grafts: the fluorinated surface reduces thrombogenicity and complement activation. The disadvantages of known surface fluorination methods, such as the cold plasma or glow discharge process, are avoided.
摘要翻译：聚合物，特别是聚酯的表面可以通过从溶液中沉积碳氟化合物来氟化。氟碳化合物可以是无定形含氟聚合物，例如以商标TEFLONAF出售的四氟乙烯和双-2,2-三氟甲基-4,5-二氟-1,2-二氧杂环戊烯的共聚物，其可溶于氟化烷烃和其他氟化液体，例如以商标FLUORINERT R出售的那些。表面氟化聚酯，特别是针织物形式，可用作血管移植物：氟化表面降低血栓形成和补体活化。已知的表面氟化方法的缺点，如冷等离子体或辉光放电过程。

3. 发明申请

WO2021123829A1 A CLEANER HEAD FOR A CLEANING APPLIANCE 审中-公开
公开(公告)号：WO2021123829A1
公开(公告)日：2021-06-24
申请号：PCT/GB2020/053311
申请日：2020-12-18
申请人： TECHTRONIC CORDLESS GP , ASHTON, Timothy
发明人： HALE, Tobias , DAVIES, Peter , BENNETT, Samuel
IPC分类号： A47L9/04 , A47L11/08 , A47L11/14 , A47L11/18 , A47L11/282 , A47L11/292 , A47L11/30 , A47L11/40 , A47L11/302 , A47L11/4041 , A47L9/0477
摘要： A cleaner head for a cleaning appliance, including: an agitator rotatable about an axis; a housing having a front side, a rear side and first and second sides which extend between the front side and rear side, said housing at least partially defining a chamber, wherein said chamber at least partially surrounds the agitator, the chamber having a dirty air inlet and a dirty air outlet, wherein the housing is movable along a surface to be cleaned; wherein the chamber includes an opening for permitting access to and removal of the agitator from the chamber; a cover cooperatively associated with the housing for permitting access to the chamber through the opening; wherein the cover is movable to an agitator access position to permit the agitator to be removed from the chamber through the opening in a direction substantially orthogonal to the axis of the agitator and in a direction which is substantially parallel to a plane of the surface to be cleaned.

4. 发明申请

WO2021123827A1 A CLEANER HEAD FOR A CLEANING APPLIANCE 审中-公开
公开(公告)号：WO2021123827A1
公开(公告)日：2021-06-24
申请号：PCT/GB2020/053309
申请日：2020-12-18
申请人： TECHTRONIC CORDLESS GP , ASHTON, Timothy
发明人： HALE, Tobias , DAVIES, Peter , BENNETT, Samuel
IPC分类号： A47L11/18 , A47L11/40 , A47L7/00 , A47L11/14 , A47L11/145 , A47L11/185 , A47L11/4088 , A47L7/0009
摘要： A cleaner head for a cleaning appliance including: an agitator rotatable about an axis; a housing having a front side, a rear side, and first and second sides which extend between the front and rear sides, said housing defining a chamber which at least partially surrounds the agitator, the chamber having a dirty air inlet and a dirty air outlet; and a spray nozzle device for spraying cleaning fluid onto the agitator in a direction towards the rear side of the housing, said spray nozzle device being fluidly connectable to a cleaning fluid supply tank of a cleaning apparatus.

5. 发明申请

WO2008007048A1 ENDOVASCULAR DEVICE AND METHOD OF FORMING SAME 审中-公开
标题翻译：内部装置及其形成方法
公开(公告)号：WO2008007048A1
公开(公告)日：2008-01-17
申请号：PCT/GB2007/002461
申请日：2007-07-02
申请人： VASCUTEK LIMITED , ASHTON, Timothy, Rawden
发明人： ASHTON, Timothy, Rawden
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2/89 , A61F2/90 , A61F2002/072 , A61F2002/075
摘要： There is provided an endovascular device useful for supporting and repairing portions of a blood vessel. The device comprises a first tubular graft layer (2) having a stent element (3) located therearound and a second graft layer (1) which covers at least part of the stent element. The first and second graft layers are securely attached together at attachment sites (5) to prevent relative movement of the stent element with respect to the graft layers. The attachment sites between the first and second graft layers are formed by laser welding wherein a near-infrared absorbing dye is applied either to the outer surface of the first tubular graft layer or to the inner surface of the second graft layer, or to both layers. The areas having dye applied are then irradiated with energy to create a laser weld.
摘要翻译：提供了一种用于支撑和修复血管部分的血管内装置。该装置包括具有位于其周围的支架元件（3）的第一管状接枝层（2）和覆盖支架元件的至少一部分的第二接枝层（1）。第一和第二接枝层在附着部位（5）牢固地附接在一起，以防止支架元件相对于接枝层的相对移动。第一和第二接枝层之间的附着位置通过激光焊接形成，其中将近红外吸收染料施加到第一管状接枝层的外表面或第二接枝层的内表面上，或施加到两层。然后用能量照射涂有染料的区域以产生激光焊接。

6. 发明申请

WO2006038031A3 SYNTHETIC PROSTHESIS FOR AORTIC ROOT REPLACEMENT 审中-公开
公开(公告)号：WO2006038031A3
公开(公告)日：2006-04-13
申请号：PCT/GB2005/003883
申请日：2005-10-07
申请人： VASCUTEK LIMITED , ASHTON, Timothy, Rawden , MAINI, Roshan , BURNS, Paul
发明人： ASHTON, Timothy, Rawden , MAINI, Roshan , BURNS, Paul
IPC分类号： A61L27/50 , A61L27/56 , A61F2/06
摘要： There is described a synthetic aortic conduit formed from two tubular porous layers having a non-bioresorbable sealant, such as SEPs, interposed therebetween. The synthetic aortic conduit can be attached to an aortic valve, such as a xenograft valve, to form an aortic root replacement prosthesis. The synthetic aortic conduit has the advantage that it can be stored in the preservative solutions required for tissue valves without degradation.

7. 发明申请

WO1996003165A1 PROSTHESES FOR THE ABDOMINAL WALL 审中-公开
标题翻译：对于ABDOMINAL WALL而言
公开(公告)号：WO1996003165A1
公开(公告)日：1996-02-08
申请号：PCT/GB1995001715
申请日：1995-07-20
申请人： VASCUTEX LIMITED , MAINI, Roshan , ASHTON, Timothy, Rawden
发明人： VASCUTEX LIMITED
IPC分类号： A61L31/00
CPC分类号： A61L31/16 , A61F2/0063 , A61L2300/404
摘要： To reduce the risk of infection in the reconstruction of the abdominal wall following hernia or other injury, a prosthesis comprises a porous material containing an antibacterial and/or other antimicrobial agent. The porous material preferably comprises a knitted polyester non-resorbable membrane, mesh or fabric substrate impregnated or enveloped with partially cross-linked (resorbable) gelatin and can be loaded with antimicrobial by soaking prior to suturing to the abdominal wall margin.
摘要翻译：为了减少在疝气或其他损伤后重建腹壁时感染的风险，假体包括含有抗菌剂和/或其它抗微生物剂的多孔材料。多孔材料优选包括浸渍或包封有部分交联（可再吸收）明胶的针织聚酯不可吸收膜，网或织物基底，并且可以在缝合到腹壁边缘之前通过浸泡加载抗微生物剂。

8. 发明申请

WO2021123828A1 A CLEANER HEAD FOR A CLEANING APPLIANCE 审中-公开
公开(公告)号：WO2021123828A1
公开(公告)日：2021-06-24
申请号：PCT/GB2020/053310
申请日：2020-12-18
申请人： TECHTRONIC CORDLESS GP , ASHTON, Timothy
发明人： BENNETT, Samuel , HALE, Tobias , DAVIES, Peter
IPC分类号： A47L9/04 , A47L9/06 , A47L11/36 , A47L11/40 , A47L11/34 , A47L7/00 , A47L11/4041 , A47L11/4044 , A47L7/0004 , A47L9/0477 , A47L9/0686
摘要： A cleaner head for a cleaning appliance, including: an agitator rotatable about an axis; a housing having a front side, a rear side, and first and second sides which extend between the front side and rear side, said housing further including a floor facing surface which extends between the front side, the rear side and the first and second sides and which, in use, faces a surface to be cleaned; wherein the housing defines a chamber which at least partially surrounds the agitator, the chamber having a dirty air inlet and a dirty air outlet; a wiper device which extends laterally between the first and second sides of the housing and which is positioned on or adjacent the floor facing surface of the housing; and a floor engaging device which extends laterally between the first and second sides of the housing and which is positioned on or adjacent the floor facing surface of the housing, said floor engaging device including an absorbent portion; wherein the wiper device and the floor engaging device are positioned rearwardly of the dirty air inlet.

9. 发明申请

WO2021123826A1 A CLEANER HEAD FOR A CLEANING APPLIANCE 审中-公开
公开(公告)号：WO2021123826A1
公开(公告)日：2021-06-24
申请号：PCT/GB2020/053308
申请日：2020-12-18
申请人： TECHTRONIC CORDLESS GP , ASHTON, Timothy
发明人： BENNETT, Samuel , DAVIES, Peter , HALE, Tobias
IPC分类号： A47L11/30 , A47L7/00 , A47L13/12 , A47L11/302 , A47L7/0009
摘要： A cleaner head for a cleaning appliance, including: a housing having a front side, a rear side, and first and second sides which extend between the front side and the rear side, the housing further including a floor facing surface which extends between the front side, rear side and first and second sides which, in use, faces a surface to be cleaned; and a floor engaging device which is connected to the floor facing surface of the housing and which extends laterally between the first and second sides of the housing, said floor engaging device including: a first portion for absorbing liquid from a surface to be cleaned; and a second portion positioned closer to either a front side or a rear side of the housing, said second portion being relatively stiff compared to the first portion.

10. 发明申请

WO2006038031A2 SYNTHETIC PROSTHESIS 审中-公开
标题翻译：合成PROSTHESIS
公开(公告)号：WO2006038031A2
公开(公告)日：2006-04-13
申请号：PCT/GB2005003883
申请日：2005-10-07
申请人： VASCUTEK LTD , ASHTON TIMOTHY RAWDEN , MAINI ROSHAN , BURNS PAUL
发明人： ASHTON TIMOTHY RAWDEN , MAINI ROSHAN , BURNS PAUL
IPC分类号： A61F2/06 , A61L27/48 , A61L27/50 , A61L27/56
CPC分类号： A61F2/06 , A61L27/48 , A61L27/507 , A61L27/56
摘要： There is described a synthetic aortic conduit formed from two tubular porous layers having a non-bioresorbable sealant, such as SEPs, interposed therebetween. The synthetic aortic conduit can be attached to an aortic valve, such as a xenograft valve, to form an aortic root replacement prosthesis. The synthetic aortic conduit has the advantage that it can be stored in the preservative solutions required for tissue valves without degradation.
摘要翻译：描述了由两个管状多孔层形成的合成主动脉导管，其中具有非生物可再吸收的密封剂，例如SEPs。合成主动脉导管可以连接到主动脉瓣，例如异种移植瓣膜，以形成主动脉根部替代假体。合成主动脉导管的优点是可以将其储存在组织瓣膜所需的防腐溶液中，而不会降解。

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