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1. 发明申请

WO2016034863A1 POLYMERIC MATERIALS 审中-公开
标题翻译：聚合材料
公开(公告)号：WO2016034863A1
公开(公告)日：2016-03-10
申请号：PCT/GB2015/052490
申请日：2015-08-27
申请人： COLORMATRIX HOLDINGS, INC. , APPLEDENE LIMITED
发明人： OVEREND, Andrew , BROWN, Patrick , DAVIES, Neil
IPC分类号： C08L67/00 , C09C3/12 , C08J3/22 , B29C49/06
CPC分类号： C08J3/226 , B01J13/0039 , B29B2911/00 , B29C45/0013 , B29C49/06 , B29C2045/0015 , C08J2300/22 , C08J2367/00 , C08J2483/04 , C08L67/00 , C08L83/04 , C09C3/12 , C08L83/00
摘要： A method of producing a product, for example a stretch blow moulded container having a metallic or pearlescent appearance, comprises selecting a mass, for example a container preform, comprising a thermoplastic polymer which incorporates a carrier polymer and stretching the thermoplastic polymer during production of said product, for example from said mass. Said carrier polymer is suitably polydimethylsiloxane and the mass may be made in a process which comprises contacting a thermoplastic polymer with a liquid formulation comprising carrier polymer and colourant.
摘要翻译：一种制造产品的方法，例如具有金属或珠光外观的拉伸吹塑成型容器，包括选择包含热塑性聚合物的容器，例如容器预制件，其包含载体聚合物并在所述的产品，例如从所述的质量。所述载体聚合物适当地是聚二甲基硅氧烷，并且该组合物可以包括使热塑性聚合物与包含载体聚合物和着色剂的液体制剂接触的方法制备。

2. 发明申请

WO2014122425A1 RECEPTACLE, METHOD OF PRODUCING A MIXED LIQUID FORMULATION AND APPARATUS THEREFOR 审中-公开
标题翻译：接头，混合液体配方的制造方法及其装置
公开(公告)号：WO2014122425A1
公开(公告)日：2014-08-14
申请号：PCT/GB2014/050195
申请日：2014-01-27
申请人： COLORMATRIX HOLDINGS, INC. , APPLEDENE LIMITED
发明人： JONES, Brian , PICKLES, Jon , BAKER, Harry
IPC分类号： B65D77/06 , B01F9/00 , B01F15/00
CPC分类号： B01F9/0023 , B01F9/0001 , B01F15/0074 , B01F15/00753 , B65B3/04 , B65D5/40 , B65D77/062 , B65D77/065
摘要： A bag-in-a-box includes a box part (40) made from a cardboard blank along with a liner (4) which is collapsible. The liner 14 includes a first elongate substantially rectangular tab (32) and a second elongate substantially rectangular tab (34). The first tab (32) is hinged about a weakened portion (36) and the second tab is hinged about a weakened portion (38). The first and second tabs are arranged to secure the liner within the box (40). The liner (14) is positioned within the box (40) and the tab (34) secured in position between two flaps of the box, so upwardly and downwardly facing faces of the tab 34 make face to face contact with respective flaps of the box. Tab (32) of the receptacle 10 is secured between flaps (44), (46) and (48). A gyroscopic mixing apparatus is used to agitate the receptacle (10) to mix its contents. With the arrangement, the mixing process and handling of the receptacle during normal use advantageously does not significantly damage the liner (14) or box part (40).
摘要翻译：包装盒包括由纸板坯料制成的盒部件（40）以及可折叠的衬垫（4）。衬套14包括第一细长大致矩形的突片（32）和第二细长的大致矩形的突片（34）。第一突片（32）围绕弱化部分（36）铰接，并且第二突片围绕弱化部分（38）铰接。第一和第二突出部布置成将衬垫固定在箱体（40）内。衬套（14）定位在箱体（40）内，并且突片（34）固定在盒子的两个翼片之间的适当位置，因此，突出部分34的面向上和向下的表面与箱体的各个翼片面对面接触。容器10的突片（32）固定在翼片（44），（46）和（48）之间。陀螺混合装置用于搅拌容器（10）以混合其内容物。通过这种布置，在正常使用期间的容器的混合过程和处理有利地不会显着损坏衬套（14）或盒部件（40）。

3. 发明申请

WO1996033211A1 BIOLOGICALLY ACTIVE PEPTIDES AND COMPOSITIONS, THEIR USE 审中-公开
标题翻译：生物活性肽和组合物，其使用
公开(公告)号：WO1996033211A1
公开(公告)日：1996-10-24
申请号：PCT/GB1996000942
申请日：1996-04-22
申请人： UNIVERSITY OF BRITISH COLUMBIA , UNIVERSITY OF ALBERTA , APPLEDENE LIMITED , ANDERSEN, Raymond , COLEMAN, John , DE SILVA, Dilip , KONG, Fangming , PIERS, Edward , WALLACE, Debra , ROBERGE, Michel , ALLEN, Theresa
发明人： UNIVERSITY OF BRITISH COLUMBIA , UNIVERSITY OF ALBERTA , APPLEDENE LIMITED
IPC分类号： C07K05/027
CPC分类号： C07K5/0205 , A61K38/00 , C07K5/0827
摘要： Compounds of general formula (I) wherein: R1 and R70 independently represent a hydrogen atom or an optionally substituted alkyl or acyl group; R2 represents a hydrogen atom or an optionally substituted alkyl or acyl group or is absent when R6 represents a group -CH= as hereinafter described; R73 represents a hydrogen atom or an optional substituent or is absent when R6 represents a methylene group or a group -CH= as hereinafter described; Y represents an optional substituent; n represents 0, 1, 2, 3, or 4; R3 represents a hydrogen atom, or an optionally substituted alkyl group; R74 represents a hydrogen atom, a hydroxy group or an optionally substituted alkyl or acyl group; R7 represents a hydrogen atom or an alkyl group; R75 represents an optionally substituted alkyl group; and i) R6 and R71 independently represent a hydrogen atom or an optionally substituted alkyl or acyl group; and R72 represents a hydrogen atom; or ii) R71 represents a hydrogen atom or an optionally substituted alkyl or acyl group and R72 represents a hydrogen atom or R71 and R72 each represent radicals so that a double bond is formed between the carbon atoms to which they are attached; and R6 represents an optionally substituted methylene group bonded to the indole moiety thereby to form a tricyclic moiety; or R6 represents an optionally substituted group -CH= bonded to the indole moiety thereby to form an aromatic tricyclic moiety; for use in therapy and as antimitotic reagents are described. Novel hemiasterlins, criamides and geodiamolides are also described.
摘要翻译：通式（I）的化合物，其中：R 1和R 70独立地表示氢原子或任选取代的烷基或酰基; R2表示氢原子或任选取代的烷基或酰基，或当R6表示基团-CH =时不存在，如下所述; 当R 6表示亚甲基或-CH =如下所述时，R 73表示氢原子或任选的取代基或不存在; Y表示任选的取代基; n表示0,1,2,3或4; R3表示氢原子或任选取代的烷基; R 74表示氢原子，羟基或任选取代的烷基或酰基; R7表示氢原子或烷基; R75表示任选取代的烷基; 和i）R 6和R 71独立地表示氢原子或任选取代的烷基或酰基; R 72表示氢原子; 或ii）R 71表示氢原子或任选取代的烷基或酰基，R 72表示氢原子或R 71和R 72各自表示基团，使得在它们所连接的碳原子之间形成双键; 并且R 6表示与吲哚部分键合的任选取代的亚甲基，从而形成三环部分; 或R6表示与吲哚部分键合的任选取代的基团-CH =，从而形成芳族三环部分; 用于治疗和用作抗有益剂的试剂。还描述了新型半球磨石，三酰胺和地iam iam苷。

4. 发明申请

WO1995018611A1 3-(7-OXO-1-AZA-4-OXABICYCLO[3.2.0]HEPT-3-YL) ALANINE DERIVATIVE AS ANTITUMOR AGENT 审中-公开
标题翻译： 3-（7-OXO-1-AZA-4-氧杂环戊二烯[3.2.0] HEPT-3-YL）作为抗菌剂的ALANINE衍生物
公开(公告)号：WO1995018611A1
公开(公告)日：1995-07-13
申请号：PCT/GB1995000023
申请日：1995-01-06
申请人： TAIHO PHARMACEUTICAL CO. LIMITED , SYNPHAR LABORATORIES, INC. , APPLEDENE LIMITED , SINGH, Rajeshwar , YAMASHITA, Tomohiro , FIAKPUI, Charles , THOMAS, George , HA, Chan , MATSUMOTO, Hiroshi , OTANI, Toshio , OIE, Shinji , MICETICH, Ronald
发明人： TAIHO PHARMACEUTICAL CO. LIMITED , SYNPHAR LABORATORIES, INC. , APPLEDENE LIMITED
IPC分类号： A61K31/42
CPC分类号： A61K31/42
摘要： The present invention relates to the use of 3-(7-oxo-1-aza-4-oxabicyclo[3.2.0]hept-3-yl) alanine derivatives of formula (I) or a pharmaceutically acceptable salt thereof, as antitumor agents, wherein R is hydrogen or COOR2; wherein R2 is C1-C3 alkyl group which may be substituted with aryl group; R1 is hydrogen or C1-C3 alkyl group which may be substituted with one or two aryl groups.
摘要翻译：本发明涉及式（I）的3-（7-氧代-1-氮杂-4-氧杂双环[3.2.0]庚-3-基）丙氨酸衍生物或其药学上可接受的盐作为抗肿瘤剂其中R是氢或COOR 2; 其中R2是可以被芳基取代的C1-C3烷基; R 1是氢或被一个或两个芳基取代的C 1 -C 3烷基。

5. 发明申请

WO2023057767A1 COMPOSITIONS AND METHODS 审中-公开
公开(公告)号：WO2023057767A1
公开(公告)日：2023-04-13
申请号：PCT/GB2022/052535
申请日：2022-10-06
申请人： INNOSPEC ACTIVE CHEMICALS LLC , APPLEDENE LIMITED
发明人： COTRELL, Phillip Loraine
IPC分类号： C11D1/94 , A61K8/37 , A61K8/42 , A61K8/46 , A61Q5/02 , A61Q19/10 , C11D3/00 , C11D11/00 , C11D1/12 , C11D1/66 , C11D1/90 , C11D1/92 , A61K2800/436 , A61K8/375 , A61K8/442 , A61K8/466 , C11D1/126 , C11D1/667 , C11D11/0094 , C11D3/0089
摘要： A concentrate composition comprising: (a) at least 10 wt% of a glycol ester of a fatty acid; (b) at least one acyl alkyl isethionate surfactant of formula (I): wherein R 1 represents an optionally substituted C 4-C 36 hydrocarbyl group; each of R 2, R 3, R 4 and R 5 independently represents hydrogen or a C 1-C 4 alkyl group and wherein at least one of R 2, R 3, R 4 and R 5 is not hydrogen; and M + represents a cation; and (c) at least one zwitterionic or amphoteric surfactant.

6. 发明申请

WO2022162348A1 AQUEOUS FRICTION REDUCER FORMULATIONS 审中-公开
公开(公告)号：WO2022162348A1
公开(公告)日：2022-08-04
申请号：PCT/GB2022/050186
申请日：2022-01-25
申请人： INDEPENDENCE OILFIELD CHEMICALS LLC , APPLEDENE LIMITED
发明人： DAWSON, Jeff , YANG, Chao , MACEWEN, Kimberley
IPC分类号： C09K8/035 , C09K8/66 , C09K8/68 , C09K8/88
摘要： An aqueous formulation for slick water fracturing comprises: (i) a polymer (AA) which includes acrylamido repeat units and may be a polyacrylamide; (ii) water; (iii) a quaternary ammonium compound.

7. 发明申请

WO2021181098A1 SOLID CLEANSING COMPOSITION 审中-公开
公开(公告)号：WO2021181098A1
公开(公告)日：2021-09-16
申请号：PCT/GB2021/050600
申请日：2021-03-10
申请人： INNOSPEC ACTIVE CHEMICALS LLC , APPLEDENE LIMITED
发明人： COTRELL, Phillip Loraine , OVERCASH, Derek Michael , COHEN, Mitchell Jared
IPC分类号： A61Q19/10 , C11D17/00 , C11D1/00 , C11D3/20 , C11D3/382 , A61K8/02 , A61K8/34 , A61K8/46 , A61K8/73 , A61K8/92
摘要： A solid cleansing composition comprising: (i) from 40 to 60 wt% of at least one acyl isethionate surfactant of the formula (I): wherein R¹ represents an optionally substituted C4C36 hydrocarbyl group; and M+ represents a cation; (ii) from 10 to 25 wt% of a C2-C8 polyhydroxy alcohol; and (iii) from 10 to 25 wt% of water.

8. 发明申请

WO2020178550A1 SUBTERRANEAN FORMATIONS 审中-公开
公开(公告)号：WO2020178550A1
公开(公告)日：2020-09-10
申请号：PCT/GB2020/050428
申请日：2020-02-24
申请人： INDEPENDENCE OILFIELD CHEMICALS LLC , APPLEDENE LIMITED
发明人： MACEWEN, Kimberley , HOEMAN, Kurt , DAWSON, Jeff
IPC分类号： C09K8/68 , C09K8/88
摘要： A method of treating a subterranean formation, for example a subterranean formation susceptible to formation of a undesirable gel-like goo,is described. The method comprises contacting the formation with a fluid (A) comprising a polymer (PP) which includes a pendent group which includes a moiety wherein the sulphur atom of the moiety is covalently bonded, optionally via a linking atom or group, to the backbone of the polymer.

9. 发明申请

WO2016063013A1 POLYMERIC MATERIALS 审中-公开
标题翻译：聚合材料
公开(公告)号：WO2016063013A1
公开(公告)日：2016-04-28
申请号：PCT/GB2015/053063
申请日：2015-10-15
申请人： COLORANT CHROMATICS AG , APPLEDENE LIMITED
发明人： MOLONEY, Steven John
IPC分类号： C08K3/28 , C08L27/00 , C08L27/18 , C08J5/18
CPC分类号： C08J5/18 , C08J2327/18 , C08J2427/18 , C08K3/22 , C08K3/28 , C08K2003/2258 , C08L27/12
摘要： A film for use in architectural applications (e.g. for roofs, walls or windows of buildings) comprises a polymeric material and an additive, wherein said polymeric material is a fluoropolymer and said additive is selected from titaniumnitride and tungsten oxide. Preferred polymeric materials may be ethylene chlorotrifluoroethylene (ECTFE) or an ethylene- tetrafluoroethylene copolymer (ETFE).
摘要翻译：用于建筑应用（例如建筑物的屋顶，墙壁或窗户）的胶片包括聚合材料和添加剂，其中所述聚合材料是含氟聚合物，所述添加剂选自氮化钛和氧化钨。优选的聚合物材料可以是乙烯氯三氟乙烯（ECTFE）或乙烯 - 四氟乙烯共聚物（ETFE）。

10. 发明申请

WO2014207472A2 POLYMERIC MATERIALS 审中-公开
标题翻译：聚合材料
公开(公告)号：WO2014207472A2
公开(公告)日：2014-12-31
申请号：PCT/GB2014/051956
申请日：2014-06-26
申请人： COLORMATRIX HOLDINGS, INC. , APPLEDENE LIMITED
发明人： OVEREND, Andrew , CAMPBELL, Ian , JONES, Brian
IPC分类号： F04C11/00
CPC分类号： F04C2/10 , B29B7/94 , F04B23/12 , F04C2/084 , F04C2/1071 , F04C2/18 , F04C11/005 , F04C2220/24 , F04C2230/602
摘要： High pressure injection apparatus (2) for addition of a liquid formulation into a melt stream comprises a first pump which is arranged to accurately meter the liquid formulation (including highly loaded formulations comprising solids comprising particles of relatively large size) and a second pump which boosts the pressure of the formulation to that of the melt stream into which it is to be injected. In an embodiment, the apparatus includes a tank (4) for initially receiving liquid formulation. The tank is subjected to ambient temperature and pressure and need not be stirred or otherwise agitated. The tank is arranged to deliver the formulation via pipe (6) into a first pump (8) (which may be a diaphragm pump or a progressing cavity pump). The pump is arranged to work at a pressure up to 120 bar to boost pressure. Downstream of pump (8), a pipe (10) is arranged to deliver formulation from the pump ()8 to a gear pump (12), driven by a motor (13). The gear pump acts to meter the liquid formulation. In an alternative embodiment, apparatus may include a progressing cavity pump to meter formulation and a gear pump to increase pressure. The apparatus may be used to inject a fluid formulation into a melted polymeric material.
摘要翻译：用于将液体制剂加入到熔体流中的高压注射装置（2）包括第一泵，其布置成精确地计量液体制剂（包括含有包含相对大尺寸的颗粒的固体的高负荷制剂）和第二泵，制剂的压力与其将被注入的熔体流的压力。在一个实施方案中，该装置包括用于最初接收液体制剂的罐（4）。该罐经受环境温度和压力，不需要搅拌或以其它方式搅拌。罐被布置成通过管道（6）将配方输送到第一泵（8）（其可以是隔膜泵或进行空腔泵）。泵被设置为在高达120巴的压力下工作以增加压力。在泵（8）的下游，管道（10）布置成将制剂从泵（8）输送到齿轮泵（12），由马达（13）驱动。齿轮泵用于测量液体配方。在替代实施例中，装置可以包括用于计量配方的前进空腔泵和用于增加压力的齿轮泵。该装置可以用于将流体制剂注入熔融的聚合物材料中。

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