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1. 发明申请

WO2010008568A1 TM4SF4 AND MODULATORS THEREOF AND METHODS FOR THEIR USE 审中-公开
标题翻译： TM4SF4及其调制器及其使用方法
公开(公告)号：WO2010008568A1
公开(公告)日：2010-01-21
申请号：PCT/US2009/004121
申请日：2009-07-15
申请人： THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK , SUSSEL, Lori , ANDERSON, Keith, Robert
发明人： SUSSEL, Lori , ANDERSON, Keith, Robert
IPC分类号： A61K48/00 , C12N5/00
CPC分类号： C12N15/1138 , C12N2310/11 , C12N2310/3233
摘要： The present invention relates to methods for modulating a β-cell population using a TM4SF4 modulator or a modulator of a TM4SF4 homolog. More particularly, the invention relates, inter alia, to methods and compositions for generating, expanding, and maintaining a β-cell population and treatment of diseases associated with the loss of β-cells using a TM4SF4 modulator or a modulator of a TM4SF4 homolog.
摘要翻译：本发明涉及使用TM4SF4调节剂或TM4SF4同源物的调节剂调节β细胞群体的方法。更具体地，本发明特别涉及用于产生，扩增和维持β细胞群体并使用TM4SF4调节剂或TM4SF4同源物的调节剂治疗与β细胞丧失相关的疾病的方法和组合物。

2. 发明申请

WO2007143782A1 INSULATION 审中-公开
标题翻译：绝缘
公开(公告)号：WO2007143782A1
公开(公告)日：2007-12-21
申请号：PCT/AU2007/000822
申请日：2007-06-13
申请人： AIR-CELL INNOVATIONS PTY LTD , ANDERSON, Keith, Robert , GIBSON, Ian, Scott
发明人： ANDERSON, Keith, Robert , GIBSON, Ian, Scott
IPC分类号： E04B1/78 , F16L59/06 , F16L59/08
CPC分类号： F16L59/029 , E04B1/78 , E04B2001/7691 , F16L59/08
摘要： Insulation sheeting (10) comprising two outer layers (11, 12) and a closed cell structure (13) bonded therebetween. The sheeting (10) is of a thickness which allows it to be disposed in a rolled configuration and also unrolled to assume a substantially flat configuration. The outer layers (11, 12) each comprises reinforced reflective aluminium foil. The closed cell foam structure (13) comprises flexible light gauge foam such as cross-linked LDPE foam. The outer surface of one of the layers (11, 12) is treated to provide some glare reduction while retaining heat reflective characteristics. Because of the closed cell structure (13), the insulation sheeting (10) can compress under load for fixing while still affording worthwhile insulation benefits. For certain applications, the insulation sheeting (10) may be perforated for air and water vapour permeability.
摘要翻译：绝缘片（10）包括两个外层（11,12）和封闭的单元结构（13）。片材（10）具有允许其以卷绕构造布置并且还展开以呈现基本平坦的构造的厚度。外层（11,12）各自包括增强的反光铝箔。闭孔泡沫结构（13）包括柔性轻量规泡沫如交联LDPE泡沫。处理一层（11,12）的外表面以提供一些眩光减少，同时保持热反射特性。由于闭孔结构（13），绝缘片（10）可以在负载下压缩固定，同时仍然提供有价值的绝缘优点。对于某些应用，绝缘片（10）可以穿孔以获得空气和水蒸气透过性。

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