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    • 1. 发明申请
    • LIGHTING FIXTURE
    • 照明灯具
    • WO2007125520A1
    • 2007-11-08
    • PCT/IB2007/051623
    • 2007-05-02
    • DELTA LIGHT NVAMELOOT, Paul
    • AMELOOT, Paul
    • F21S8/02F21Y101/02
    • F21S8/02F21S2/005F21V19/003F21Y2107/10F21Y2107/20F21Y2115/10H05B33/0803H05B33/0845
    • The invention relates to a lighting fixture (1, 2), comprising a hollow space (10, 20) which is provided with two or more groups (A, A 1 , A 2 , A 3 , A 4 ) of light sources (100) for lighting one or more objects (200, 201, 202, 203) through an opening (11, 21) in the lighting fixture (1, 2), in which each group (A, A 1 , A 2 , A 3 , A 4 ) comprises at least one light source (100), and in which the light sources (A, A 1 , A 2 , A 3 , A 4 ) are arranged statically in said hollow space (10, 20), and in which the light sources (100) are arranged inside said hollow space (10, 20) in an essentially dome-shaped configuration.
    • 本发明涉及一种照明器具(1,2),其包括设置有两个或更多个组(A,A 1,A 2,N 2)的中空空间(10,20) 用于通过一个开口(11,11)向一个或多个物体(200,201,202,203)照射一个或多个物体(200,201,202,203)的光源(100) 21),其中每组(A,A 1,A 2,A 3,A,A 2, 至少一个光源(100),其中光源(A,A 1,A 2,A 2, 在上述中空空间(10,20)中静止地配置有3个以上的3个以上的空气,其中,光源(100)配置在上述中空空间(10,20)的内部 )在基本上圆顶形的配置中。
    • 2. 发明申请
    • HETERO-OLIGOMERIC COMPOUNDS DERIVED FROM THE TNF CYTOKINE SUPERFAMILY AND THEIR USE
    • 从TNF细胞因子超级细胞衍生的异源寡聚化合物及其使用
    • WO0234780A3
    • 2002-07-11
    • PCT/EP0112422
    • 2001-10-25
    • VLAAMS INTERUNIV INST BIOTECHAMELOOT PAULBROUCKAERT PETERFIERS WALTER
    • AMELOOT PAULBROUCKAERT PETERFIERS WALTER
    • C07K14/52C07K14/525G01N33/68
    • C07K14/525C07K14/52
    • The invention relates to a method to form artificial, hetero-oligomeric complexes of proteins that do normally occur in homo-oligomeric complexes. Said hetero-oligomeric complexes do have a biological activity that is similar or identical to the activity of the homo-oligomeric complexes.The current invention also relates to a method to use said hetero-oligomeric complexes to screen for compounds that can stabilize said hetero-oligomeric complexes, or to screen for compounds that dissociate said hetero-oligomeric complexes into monomers, which are not biologically active, or show a biological activity, which is clearly distinct from that of the hetero-oligomeric complexes, or to screen for compounds that inhibit the oligomerisation or reoligomerisation of monomers in oligomeric complexes.Furthermore, the invention relates to pharmaceutical compositions comprising said compounds.
    • 本发明涉及一种通常在同型寡聚复合物中发生的蛋白质的人造异寡聚复合物的方法。 所述异寡聚复合物确实具有与同型寡聚复合物的活性相似或相同的生物活性。本发明还涉及使用所述异寡聚复合物筛选可稳定所述异源寡聚复合物的化合物的方法, 或者筛选将所述杂寡聚复合物分解成单体的化合物,所述单体不具有生物活性,或显示与异低聚物复合物明显不同的生物活性,或筛选抑制 寡聚复合物中单体的低聚或再偶联。此外,本发明涉及包含所述化合物的药物组合物。