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1. 发明申请

WO2002098145A1 3D DISPLAY USING MICROMIRRORS ARRAY 审中-公开
标题翻译：使用MICROMIRRORS ARRAY的3D显示
公开(公告)号：WO2002098145A1
公开(公告)日：2002-12-05
申请号：PCT/US2002/016870
申请日：2002-05-29
申请人： UNIVERSITY OF CINCINNATI , KOWEL, Stephen, T. , YAN, Jun , CHO, Hyong, Jin , AHN, Chong, H.
发明人： KOWEL, Stephen, T. , YAN, Jun , CHO, Hyong, Jin , AHN, Chong, H.
IPC分类号： H04N13/04
CPC分类号： H04N13/365 , H04N13/302
摘要： Method and apparatus incorporates relaying (22) and collecting lens (24) to gather, direct and enlarge three-dimensional light images reflected from an array of interleaved and/or plastic-based micromirrors (10).
摘要翻译：方法和装置包括中继（22）和收集透镜（24）以收集，引导和放大从交错和/或基于塑料的微镜（10）阵列反射的三维光图像。

2. 发明申请

WO2011011350A2 MICROFLUIDIC ASSAY PLATFORMS 审中-公开
标题翻译：微流感测定平台
公开(公告)号：WO2011011350A2
公开(公告)日：2011-01-27
申请号：PCT/US2010042506
申请日：2010-07-20
申请人： SILOAM BIOSCIENCES INC , PUNTAMBEKAR ANIRUDDHA , KAI JUNHAI , LEE SE HWAN , AHN CHONG H
发明人： PUNTAMBEKAR ANIRUDDHA , KAI JUNHAI , LEE SE HWAN , AHN CHONG H
IPC分类号： B01L3/00
CPC分类号： B01L3/5025 , B01L3/50273 , B01L3/5085 , B01L2300/069 , B01L2300/0829 , B01L2300/0851 , B01L2300/0861 , B01L2300/088 , B01L2300/0883 , B01L2300/161 , B01L2400/0406
摘要： This invention discloses novel improvements to conventional microtiter plates, involving integrating microfluidic channels with such microtiter plates to simplify the assay operation, Increase operational speed and reduce reagent consumption. The present invention can be used in place of a conventional microliter plate and can be easily substituted without any changes to the existing instrumentation systems designed for microtiter plates. The invention also discloses a microfluidic device integrated with sample loading wells wherein the entire flow process is capillary driven.
摘要翻译：本发明公开了对常规微量滴定板的新颖改进，涉及将微流体通道与这种微量滴定板结合，以简化测定操作，提高操作速度和减少试剂消耗。本发明可以用于代替传统的微升板，并且可以容易地替代，而不会改变设计用于微量滴定板的现有仪器系统。本发明还公开了一种与样品加载井集成的微流体装置，其中整个流动过程是毛细管驱动的。

3. 发明申请

WO2006088976A3 FIBER-OPTIC BIOSENSOR AND BIOSENSING METHODS 审中-公开
标题翻译：光纤生物传感器和生物传感方法
公开(公告)号：WO2006088976A3
公开(公告)日：2009-08-20
申请号：PCT/US2006005376
申请日：2006-02-16
申请人： UNIV LOUISVILLE RES FOUND , KANG KYUNG AIH , AHN CHONG H
发明人： KANG KYUNG AIH , AHN CHONG H
IPC分类号： G01N33/53 , G01N21/00 , G01N21/64 , G01N33/532 , G01N33/533
CPC分类号： G01N33/54373 , B82Y15/00 , B82Y30/00
摘要： A method for biosensing that includes passing, via convective flow, a sample believed to contain one or more target biomarkers through a micro fluidic channel and over the surface of an optical waveguide that has been prepared to bind the one or more target biomarkers, and sensing for an emission output from the optical waveguide at a wavelength that is characteristic of the binding of the target biomarker. A biosensor device that includes a module defining at least one microfluidic channel, an optical waveguide exposed along at least a portion of its length to fluid flow within the microfluidic channel, where a surface of the optical waveguide being prepared to bind a target biomarker, and an excitation source to couple an excitation wavelength of light into the optical waveguide. The device also includes a sensor for detecting emission light from the optical waveguide at an emission wavelength characteristic of binding of the target biomarker.
摘要翻译：一种用于生物传感的方法，其包括通过对流流经被认为含有一种或多种目标生物标志物的样品通过微流体通道并且已经准备好结合一种或多种靶生物标志物的光波导的表面，以及感测用于以目标生物标志物结合的特征的波长从光波导发射的光。一种生物传感器装置，其包括限定至少一个微流体通道的模块，沿其长度的至少一部分暴露于所述微流体通道内的流体流动的光波导，其中所述光波导的表面准备结合靶标生物标志物，以及用于将光的激发波长耦合到光波导中的激发源。该装置还包括用于以目标生物标志物结合的发射波长特性检测来自光波导的发射光的传感器。

4. 发明申请

WO2006088976A2 FIBER-OPTIC BIOSENSOR AND BIOSENSING METHODS 审中-公开
标题翻译：光纤生物传感器和生物传感方法
公开(公告)号：WO2006088976A2
公开(公告)日：2006-08-24
申请号：PCT/US2006/005376
申请日：2006-02-16
申请人： UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. , KANG, Kyung Aih , AHN, Chong, H.
发明人： KANG, Kyung Aih , AHN, Chong, H.
IPC分类号： G01N33/53 , G01N33/537 , G01N33/543
CPC分类号： G01N33/54373 , B82Y15/00 , B82Y30/00
摘要： A method for biosensing that includes passing, via convective flow, a sample believed to contain one or more target biomarkers through a micro fluidic channel and over the surface of an optical waveguide that has been prepared to bind the one or more target biomarkers, and sensing for an emission output from the optical waveguide at a wavelength that is characteristic of the binding of the target biomarker. A biosensor device that includes a module defining at least one microfluidic channel, an optical waveguide exposed along at least a portion of its length to fluid flow within the microfluidic channel, where a surface of the optical waveguide being prepared to bind a target biomarker, and an excitation source to couple an excitation wavelength of light into the optical waveguide. The device also includes a sensor for detecting emission light from the optical waveguide at an emission wavelength characteristic of binding of the target biomarker.
摘要翻译：一种用于生物传感的方法，其包括经由对流使被认为包含一种或多种目标生物标志物的样品通过微流体通道并在光波导的表面上方通过，该光波导已经准备好将一个或多个目标生物标志物，并在特征在于目标生物标志物结合的波长处感测来自光波导的发射输出。一种生物传感器装置，其包括限定至少一个微流体通道的模块，沿着其长度的至少一部分暴露于微流体通道内的流体流动的光波导，其中该光波导的表面准备结合目标生物标志物，以及用于将光的激发波长耦合到光波导中的激发源。该装置还包括传感器，用于以目标生物标志物结合的发射波长特征检测来自光波导的发射光。

5. 发明申请

WO2006088976A8 FIBER-OPTIC BIOSENSOR AND BIOSENSING METHODS 审中-公开
标题翻译：光纤生物传感器和生物传感方法
公开(公告)号：WO2006088976A8
公开(公告)日：2006-10-19
申请号：PCT/US2006005376
申请日：2006-02-16
申请人： UNIV LOUISVILLE RES FOUND , KANG KYUNG AIH , AHN CHONG H
发明人： KANG KYUNG AIH , AHN CHONG H
IPC分类号： G01N33/53 , G01N33/537 , G01N33/543
CPC分类号： G01N33/54373 , B82Y15/00 , B82Y30/00
摘要： A method for biosensing that includes passing, via convective flow, a sample believed to contain one or more target biomarkers through a micro fluidic channel and over the surface of an optical waveguide that has been prepared to bind the one or more target biomarkers, and sensing for an emission output from the optical waveguide at a wavelength that is characteristic of the binding of the target biomarker. A biosensor device that includes a module defining at least one microfluidic channel, an optical waveguide exposed along at least a portion of its length to fluid flow within the microfluidic channel, where a surface of the optical waveguide being prepared to bind a target biomarker, and an excitation source to couple an excitation wavelength of light into the optical waveguide. The device also includes a sensor for detecting emission light from the optical waveguide at an emission wavelength characteristic of binding of the target biomarker.
摘要翻译：一种用于生物传感的方法，其包括通过对流流经被认为含有一种或多种目标生物标志物的样品通过微流体通道并且已经准备好结合一种或多种靶生物标志物的光波导的表面，以及感测用于以目标生物标志物结合的特征的波长从光波导发射的光。一种生物传感器装置，其包括限定至少一个微流体通道的模块，沿其长度的至少一部分暴露于所述微流体通道内的流体流动的光波导，其中所述光波导的表面准备结合靶标生物标志物，以及用于将光的激发波长耦合到光波导中的激发源。该装置还包括用于以目标生物标志物结合的发射波长特性检测来自光波导的发射光的传感器。

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