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1. 发明申请

WO2006047273A3 METHOD AND APPARATUS FOR NONINVASIVE GLUCOSE CONCENTRATION ESTIMATION THROUGH NEAR-INFRARED SPECTROSCOPY 审中-公开
标题翻译：通过近红外光谱法测定非葡萄糖浓度估算方法和装置
公开(公告)号：WO2006047273A3
公开(公告)日：2007-02-22
申请号：PCT/US2005037860
申请日：2005-10-20
申请人： SENSYS MEDICAL INC , ACOSTA GEORGE M , ABUL-HAJ N ALAN , RUCHTI TIMOTHY L , MONFRE STEPHEN L , BLANK THOMAS B , HAZEN KEVIN H
发明人： ACOSTA GEORGE M , ABUL-HAJ N ALAN , RUCHTI TIMOTHY L , MONFRE STEPHEN L , BLANK THOMAS B , HAZEN KEVIN H
IPC分类号： A61B5/00
CPC分类号： A61B5/1455 , A61B5/14532 , A61B2560/0223 , A61B2560/0233
摘要： A near-infrared spectrometer-based analyzer attaches continuously or semicontinuously to a human subject and is used to collect spectral measurements of a tissue sample. The spectral readings are used to estimate a biological parameter in the sampled tissue noninvasively, such as glucose concentration. The preferred apparatus is a near-infrared analyzer that includes a base module and a sample module connected together with a communication bundle. The base module contains the bulk of the analyzer, such as a spectrograph and a central processing unit with an algorithm used for converting the optical signal into a glucose concentration. The sample module is typically in a smaller module that interfaces to a tissue sample. The sample module is preferably handheld and provides minimal sampling distortion due to heat or pressure.
摘要翻译：基于近红外光谱仪的分析仪连续地或半连续地连接到人类受试者并用于收集组织样本的光谱测量。光谱读数用于非侵入性地估计采样组织中的生物学参数，如葡萄糖浓度。优选的装置是近红外分析器，其包括与通信束连接在一起的基本模块和样本模块。基本模块包含分析仪的大部分，例如光谱仪和具有用于将光信号转换为葡萄糖浓度的算法的中央处理单元。样品模块通常在与组织样品接口的较小模块中。样品模块优选是手持式的，并且由于热或压力而提供最小的采样失真。

2. 发明申请

WO2009094159A1 MULTILUMEN BRACHYTHERAPY BALLOON CATHETER 审中-公开
标题翻译：多用途BRACHYTHERAPY BALLOON CATHETER
公开(公告)号：WO2009094159A1
公开(公告)日：2009-07-30
申请号：PCT/US2009/000402
申请日：2009-01-22
申请人： SENORX, INC. , ACOSTA, George, M. , LUBOCK, Paul
发明人： ACOSTA, George, M. , LUBOCK, Paul
IPC分类号： A61N5/10
CPC分类号： A61N5/1015 , A61F7/123 , A61M25/10 , A61M25/1034 , A61M25/1036 , A61M2025/0036 , A61M2025/004 , A61N1/403 , A61N2005/1018
摘要： The disclosure describes a device for asymmetrical irradiation of a body cavity or site, such as after removal of tissue, e.g. biopsy or lumpectomy. The device includes an elongated tubular shaft having an inner lumen and a tubular wall with a plurality of lumens extending within the wall which are configured for receiving a radiation source. The distal portion of the tubular shaft is cut into a plurality of longitudinally separated wall segments with a lumen extending within at least one of the wall segments. A support member is positioned within the separated wall segments to support and position the wall segments in a desired configuration for brachytherapy. An expandable member such as an inflatable balloon is mounted on the distal shaft portion about the separated wall segments wall which when inflated secures the distal shaft portion within a desired intracorporeal site for brachytherapy treatment.
摘要翻译：本公开描述了用于体腔或部位的不对称照射的装置，例如在去除组织之后，例如，活检或肿瘤切除术。该装置包括细长的管状轴，其具有内腔和管状壁，所述管状壁具有在壁内延伸的多个腔，所述多个腔在构造成用于接收辐射源。管状轴的远端部分被切割成多个纵向分离的壁段，其中内腔在至少一个壁段内延伸。支撑构件被定位在分离的壁段内以支撑和定位所需的构造的壁段用于近距离放射治疗。诸如可膨胀气囊的可膨胀构件围绕分离的壁段壁安装在远侧轴部分上，当被充气时将远端轴部分固定在期望的体内位置以进行近距离放射治疗。

3. 发明申请

WO2006047273A2 METHOD AND APPARATUS FOR NONINVASIVE GLUCOSE CONCENTRATION ESTIMATION THROUGH NEAR-INFRARED SPECTROSCOPY 审中-公开
标题翻译：通过近红外光谱法测定非葡萄糖浓度估算方法和装置
公开(公告)号：WO2006047273A2
公开(公告)日：2006-05-04
申请号：PCT/US2005/037860
申请日：2005-10-20
申请人： SENSYS MEDICAL, INC. , ACOSTA, George, M. , ABUL-HAJ, N., Alan , RUCHTI, Timothy, L. , MONFRE, Stephen, L. , BLANK, Thomas, B. , HAZEN, Kevin, H.
发明人： ACOSTA, George, M. , ABUL-HAJ, N., Alan , RUCHTI, Timothy, L. , MONFRE, Stephen, L. , BLANK, Thomas, B. , HAZEN, Kevin, H.
IPC分类号： A61B5/00
CPC分类号： A61B5/1455 , A61B5/14532 , A61B2560/0223 , A61B2560/0233
摘要： A near-infrared spectrometer-based analyzer attaches continuously or semicontinuously to a human subject and is used to collect spectral measurements of a tissue sample. The spectral readings are used to estimate a biological parameter in the sampled tissue noninvasively, such as glucose concentration. The preferred apparatus is a near-infrared analyzer that includes a base module and a sample module connected together with a communication bundle. The base module contains the bulk of the analyzer, such as a spectrograph and a central processing unit with an algorithm used for converting the optical signal into a glucose concentration. The sample module is typically in a smaller module that interfaces to a tissue sample. The sample module is preferably handheld and provides minimal sampling distortion due to heat or pressure.
摘要翻译：基于近红外光谱仪的分析仪连续地或半连续地连接到人类受试者并用于收集组织样本的光谱测量。光谱读数用于非侵入性地估计采样组织中的生物学参数，如葡萄糖浓度。优选的装置是近红外分析器，其包括与通信束连接在一起的基本模块和样本模块。基本模块包含分析仪的大部分，例如光谱仪和具有用于将光信号转换为葡萄糖浓度的算法的中央处理单元。样品模块通常在与组织样品接口的较小模块中。样品模块优选是手持式的，并且由于热或压力而提供最小的采样失真。

4. 发明申请

WO1989011834A1 MEDICAL DEVICE APPLYING LOCALIZED HIGH INTENSITY LIGHT AND HEAT, PARTICULARLY FOR DESTRUCTION OF THE ENDOMETRIUM 审中-公开
标题翻译：应用本地化高强度光和热的医疗设备，特别是用于破坏内膜
公开(公告)号：WO1989011834A1
公开(公告)日：1989-12-14
申请号：PCT/US1989002492
申请日：1989-06-07
申请人： TRIMEDYNE LASER SYSTEMS, INC. , EVERETT, Royice, B. , ACOSTA, George, M. , HUSSEIN, Hany, M., G.
发明人： TRIMEDYNE LASER SYSTEMS, INC.
IPC分类号： A61B17/36
CPC分类号： A61B18/24 , A61B17/42 , A61B18/28 , A61B2017/0007 , A61B2017/00084 , A61B2017/4216 , A61B2018/2272
摘要： A medical device (10) applies localized heat to a site in a patient's body by irradiation with light and by conduction. The device includes a radiant energy transmitting conduit (22) typically an optic fiber, that carries radiant energy, typically high intensity light such as laser, into a body cavity, typically the uterus (100), from an energy source (50) typically a laser source that is located exterior to the body through the conduit (22) and out a bulbous element (18). At the operative head of the device a portion of the transmitted radiant energy is absorbed and converted to heat and another portion of the transmitted radiant energy is emitted through an aperture in the device head as light energy suitable for more localized an intense heating and destruction of tissue.
摘要翻译：医疗装置（10）通过照射光和传导来将局部热量施加到患者体内的部位。该装置包括通常为光纤的辐射能量传输导管（22），其通常将辐射能（通常为高强度光如激光）从能量源（50）通常体现在通常为子宫（100）的体腔（50）中激光源，其通过导管（22）位于身体的外部，并且穿出球根元件（18）。在设备的操作头部，透射的辐射能的一部分被吸收并转换成热，并且透射的辐射能的另一部分通过设备头中的孔发射，作为适合于更局部的较强的加热和破坏组织。

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