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    • 2. 发明申请
    • METHOD AND APPARATUS FOR DIAGNOSING A DISEASED CONDITION IN TISSUE OF A SUBJECT
    • 用于诊断受试者组织疾病状况的方法和装置
    • WO2010086326A3
    • 2010-09-23
    • PCT/EP2010050922
    • 2010-01-27
    • SCIBASE ABAABERG PETER
    • AABERG PETER
    • A61B5/053G01R27/02
    • A61B5/0531A61B5/7267
    • The present invention relates to a method and a medical device (10) for diagnosing a diseased condition in tissue of a human or animal subject, wherein tissue electrical impedance measurements are employed. At least one set of data pre-processing rules (12a - 12d) are applied to impedance of a target tissue region and impedance of a reference tissue region (11), wherein the reference tissue region is located in close proximity to the target tissue region. The impedance data of the target tissue region and the impedance data of the reference tissue region comprises a plurality of impedance values measured in the target tissue region and the reference tissue region, respectively, wherein the tissue measurements in the two tissue regions are performed substantially concurrently or immediately consecutively. On the basis of the pre-processed data, a trained evaluation system algorithm (14) diagnoses the diseased condition in the target tissue region.
    • 本发明涉及用于诊断人或动物受试者的组织中的疾病状况的方法和医疗装置(10),其中采用组织电阻抗测量。 将至少一组数据预处理规则(12a-12d)应用于目标组织区域的阻抗和参考组织区域(11)的阻抗,其中参考组织区域位于紧邻目标组织区域 。 目标组织区域的阻抗数据和参考组织区域的阻抗数据分别包括在目标组织区域和参考组织区域中测量的多个阻抗值,其中两个组织区域中的组织测量基本上同时进行 或立即连续。 基于预处理数据,经过训练的评估系统算法(14)诊断目标组织区域中的病变状况。
    • 3. 发明申请
    • DIAGNOSING OF A DISEASED CONDITION OF THE SKIN USING IMPEDANCE
    • 使用阻力诊断皮肤疾病状况
    • WO2007068433A3
    • 2007-11-01
    • PCT/EP2006011924
    • 2006-12-12
    • SCIBASE ABOLLMAR STIGNICANDER INGRIDBIRGERSSON ULRIKCORMAN THIERRYAABERG PETER
    • OLLMAR STIGNICANDER INGRIDBIRGERSSON ULRIKCORMAN THIERRYAABERG PETER
    • A61B5/053
    • A61B5/0531A61B5/411A61B5/444A61B5/685
    • Medical apparatus for diagnosing of a diseased condition of the skin of a subject. The apparatus comprises an electrically conducting probe including a plurality of electrodes, each electrode comprising a plurality of micro-needles, wherein each electrode comprises a base substrate, said micro-needles being integrally formed with said substrate and arranged in a laterally spaced relationship apart from each other and having a length being sufficient to penetrate the stratum corneum, said micro-needles being arranged with an at least partially oblique shape. Furthermore, the present invention relates to an electrode for use in the device, arrays of micro-needle and method for the diagnostics of biological conditions using impedance measurements. The diagnostics is in particular related to cancer, and preferably skin cancer, wherein skin cancer is a basal cell carcinoma, a malignant melanoma, a squamous cell carcinoma, or precursors of such lesions.
    • 用于诊断受试者皮肤病变状况的医疗装置。 该装置包括一个包括多个电极的导电探针,每个电极包括多个微针,其中每个电极包括基底,所述微针与所述基底一体地形成并且以横向隔开的关系布置 彼此并且具有足以穿透角质层的长度,所述微针布置成至少部分倾斜的形状。 此外,本发明涉及用于该装置的电极,微针阵列和使用阻抗测量来诊断生物学条件的方法。 诊断特别涉及癌症,优选皮肤癌,其中皮肤癌是基底细胞癌,恶性黑素瘤,鳞状细胞癌或这种病变的前体。