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    • 2. 发明申请
    • METALLIC FLAT GASKET
    • 金属平板垫圈
    • WO2009098063A2
    • 2009-08-13
    • PCT/EP2009/000808
    • 2009-02-05
    • REINZ-DICHTUNGS-GMBHEGLOFF, GeorgHOEHE, KurtSCHNEIDER, Juergen
    • EGLOFF, GeorgHOEHE, KurtSCHNEIDER, Juergen
    • F02F11/00F16J15/08
    • F16J15/0818F16J15/0825
    • The invention relates to a metallic flat gasket (1) with at least one metallic gasket layer (2), which is mainly flat and shows a first and second surface (21, 22), wherein a plane of the gasket (E) runs centered between said flat areas, wherein a camber (3) is formed within the gasket layer (2), which protrudes over the first surface (21) of the gasket layer (2) and which has a larger length (L) than width (B), wherein the camber (3) possesses a first level (N1) given by a virtual level, which runs in parallel to the plane of the gasket (E) through the foot (30) of the camber (3) on the first surface (21) of the gasket layer (2) and a second level (N2), given by a further virtual level, which runs through the highest point (31) of the camber (3) and also parallel to the plane of the gasket (E) of the gasket layer (2), wherein the camber possesses a slope area (32) that ascends between the two levels (N1, N2). The slope area (32) is provided with an undulating structure (4) such that it comprises at least two waves (40) each with a wave crest (41) and a wave trough (42).
    • 本发明涉及一种具有至少一个金属垫片层(2)的金属平垫圈(1),其主要是平的,并且显示出第一和第二表面(21,22),其中垫片(E)的平面以中心 在所述平坦区域之间,其中在所述垫圈层(2)内形成有在所述垫圈层(2)的所述第一表面(21)上方突出并且具有比宽度(B ),其中所述弯度(3)具有由虚拟水平给出的第一水平面(N1),所述第一水平面平行于所述垫圈(E)的平面,所述第一水平面通过所述第一表面(3)的所述脚部(30) (2)的第二水平面(21)和由另外的虚拟水平给出的第二水平面(N2),其穿过所述弯度(3)的最高点(31)并且平行于所述垫圈的平面 E),其中所述弧度具有在所述两个水平面(N1,N2)之间上升的倾斜区域(32)。 倾斜区域(32)设置有起伏结构(4),使得其包括至少两个波浪(40),每个波浪具有波峰(41)和波谷(42)。
    • 3. 发明申请
    • METALLIC FLAT GASKET
    • 金属平板垫圈
    • WO2008128788A1
    • 2008-10-30
    • PCT/EP2008/003330
    • 2008-04-24
    • REINZ-DICHTUNGS-GMBHUNSELD, GuentherEGLOFF, GeorgHOEHE, Kurt
    • UNSELD, GuentherEGLOFF, GeorgHOEHE, Kurt
    • F16J15/08
    • F16J15/0818F16J15/0825F16J2015/085
    • The invention relates to a metallic flat gasket (1) with at least one gasket layer (2), in which at least one through opening (3) is present, which is surrounded by a sealing area (4), in which at least one elastically deformable element (5) surrounding the through opening (3) is arranged, and an optional, at least one functional area (6) with at least one elastically deformable sealing or supporting element (7), which does not separately surround a single through-opening, where outside of the at least one sealing area (4) and the optional at least one functional area (6) on at least one of the surfaces (21, 22) of at least one of the gasket layers (2) an area is surface structured in such a way that the gasket layer (2) in this area has a thickness that is larger than the original thickness of the gasket layer (2). The surface structured area (8) covers the at least one surface (21, 22) outside of the sealing (4) and the functional area (6) at least in regions and the surface structure is formed by alternating depressions (9) and protrusions (10) which run on at least one cohort of essentially parallel, straight virtual lines extending over the total area of the structured area (8).
    • 本发明涉及一种具有至少一个垫圈层(2)的金属扁平垫片(1),其中存在至少一个通孔(3),所述至少一个通孔(3)被密封区域(4)围绕,其中至少一个 布置有围绕通孔(3)的可弹性变形的元件(5)和可选的至少一个具有至少一个可弹性变形的密封或支撑元件(7)的功能区域(6),其不分开围绕单个通孔 在至少一个垫圈层(2)的至少一个表面(21,22)上的至少一个密封区域(4)和可选的至少一个功能区域(6)的外侧, 区域以这样的方式进行表面结构,使得该区域中的垫圈层(2)的厚度大于衬垫层(2)的原始厚度。 表面结构区域(8)至少在区域中覆盖密封件(4)外部的至少一个表面(21,22)和功能区域(6),并且表面结构由交替的凹陷(9)和突起 (10),其在至少一组在结构化区域(8)的总区域上延伸的基本上平行的直线虚拟线上运行。
    • 6. 发明申请
    • MOUNTING DEVICE AND METHOD FOR PRODUCING
    • 安装装置及其制造方法
    • WO2007112987A1
    • 2007-10-11
    • PCT/EP2007/002906
    • 2007-03-30
    • REINZ-DICHTUNGS-GMBHGOLLE, MatthiasHEIN, ChristophHOEHE, KurtLASKE, MatthiasRUESS, BerndSO, Hyunwoo
    • GOLLE, MatthiasHEIN, ChristophHOEHE, KurtLASKE, MatthiasRUESS, BerndSO, Hyunwoo
    • A44B18/00B23K26/38
    • A44B18/0015B23K26/21B23K26/38B23K2201/18B23K2201/20
    • The present invention thus relates to a mounting device (1) having a metallic base plate (2), on which multiple fastening elements (31) are provided, from each of which at least a partial area projects above the base plate (2). The mounting device is obtainable by incising fastening element blanks (4) into the surface of the metallic base plate (2) while leaving one connection edge (5) per blank (4) in such a way that they each have a web-shaped base area (6), which comprises the connection edge (5) on one end, and a head area (7) adjoining the base area, which projects laterally beyond the neighboring base area on at least one side. At least one partial area of the blanks (4) is bent out of the base plate around at least one bending edge located in the base area. The projecting edge of the head area adjoining the base area runs at an angle between 0° and 70° in relation to the plane of the base plate after the fastening elements are bent out of the base plate. In addition, the present invention relates to a method for producing this mounting device.
    • 因此,本发明涉及一种具有金属基板(2)的安装装置(1),其上设置有多个紧固元件(31),其中至少一部分区域突出在基板(2)的上方。 安装装置可以通过将紧固元件坯件(4)切割到金属基板(2)的表面中,同时每个坯料(4)留下一个连接边缘(5),使得它们各自具有网状基部 区域(6),其包括一端的连接边缘(5)和与基部区域相邻的头部区域(7),其在至少一个侧面上横向突出超出邻近基部区域。 坯件(4)的至少一个部分区域围绕位于基部区域中的至少一个弯曲边缘弯曲出基板。 在紧固元件从基板弯曲出来之后,与基座区域相邻的头部区域的突出边缘相对于基板的平面以0°和70°之间的角度延伸。 此外,本发明涉及一种用于制造该安装装置的方法。
    • 7. 发明申请
    • VERFAHREN ZUR HERSTELLUNG EINES VERBINDUNGSLEITUNGSSYSTEMS FÜR EIN LABORGERÄT UND/ODER MEDIZINPRODUKT
    • 用于生产连接线路系统实验室设备和/或医疗
    • WO2015113582A1
    • 2015-08-06
    • PCT/EP2014/003335
    • 2014-12-12
    • THERMO ELECTRON LED GMBH
    • SCHMEZER, ThomasHAESE, Sebastian
    • B01L3/00
    • B01L3/561B01L3/5635B01L3/565B01L2200/0689C02F1/42
    • Die Erfindung betrifft ein Verfahren zum Herstellen eines Verbindungsleitungssystems (1) für ein Laborgerät (2) und/oder Medizinprodukt (2') zum Erstellen von Fluidverbindungen (3) zwischen Komponenten (4) des Laborgeräts (2) und/oder Medizinprodukts (2') untereinander oder zu externen Komponenten (5), worin das Verbindungsleitsystem (1) umfasst: eine erste Platte (6) mit einer ersten Oberfläche (60) und einer dieser gegenüberliegenden zweiten Oberfläche (61), worin in die erste Platte (6) eine Vielzahl über die zweite Oberfläche (61) verlaufende Kanäle (62) eingetieft ist, eine zweite Platte (7), welche mit der zweiten Oberfläche (61) der ersten Platte (6) fluiddicht verbunden ist, sowie Anschlüsse (8) für zumindest einen Teil der Kanäle (62), die sich auf der ersten Oberfläche (60) der ersten Platte (6) und/oder der auf einer von der ersten Platte (6) abgewandten ersten Oberfläche (70) der zweiten Platte (7) befinden und mit einem der Kanäle (62) in Verbindung stehen, umfassend die Schritte: A) Bereitstellen der ersten Platte (6), in die eine Vielzahl über ihre zweite Oberfläche (61) verlaufende Kanäle (62) eingetieft ist, B) Bereitstellen der zweiten Platte (7), C) Aufeinanderlegen der ersten Platte (6) und der zweiten Platte (7), so dass deren zweite Oberflächen (61, 71) aufeinander zuweisen, wobei zwischen die zweiten Oberflächen (61, 71) eine Schmelzfolie (11) so eingelegt wird, dass sie sich zumindest über den Oberflächenbereich erstreckt, in dem in die zweite Platte (6) Kanäle (62) eingetieft sind, wobei das Material der Schmelzfolie einen niedrigeren Schmelzpunkt besitzt als das Material von erster und zweiter Platte (6, 7), D) Zusammenpressen von erster und zweiter Platte (6, 7) unter Erwärmung, bis das Material der Schmelzfolie (11), aber nicht das der Platten (6, 7), schmilzt und die beiden Platten (6, 7) fluiddicht verbindet.
    • 本发明涉及一种方法,用于制造连接管系统(1)用于实验室设备(2)和/或医疗装置(2“)为(3)的部件之间建立流体连接(4)的实验室设备(2)和/或医疗装置(2” )彼此之间或到外部部件(5),其中所述连接系统(1),包括:(6)具有第一表面(60)和相对的第二表面(61)的第一板,其中,在所述第一板(6) 延伸的第二表面上的多个(61)的通道(62)沉没,第二板连接到第一板的所述第二表面(61)(7)(6),其连接在流体密封,以及(8)连接于至少一部分 在第一表面上延伸的通道(62)是与(60)的第一板(6)和/或侧相反的一个的所述第二板的第一板(6)的第一表面(70)(7)用的 所述通道(62)连通, 包括以下步骤:a)提供在第一板(6)中,在多个在其第二表面(61)延伸的通道(62)被加深,B)提供叠加在第一板的第二板(7),C)( 分配6)和所述第二板(7),使得(第二面61,71)彼此连接,其中,所述第二表面(61,71)之间有插入的熔融制膜(11),使得它至少在表面区域上延伸 其中在所述第二板(6)通道(62)沉没,其中所述熔体膜的材料具有比第一和第二板的材料更低的熔点(6,7),D)压在一起的第一和第二板(6 ,7)与加热直到熔体膜(11)的材料,包括但该板(6,7)熔融并在两个板(6,7所连接的)流体密封。
    • 8. 发明申请
    • DIAGNOSTIC USE OF PROSOMATOSTATIN
    • 诊断使用前列腺素
    • WO2012167887A1
    • 2012-12-13
    • PCT/EP2012/002313
    • 2012-05-31
    • B.R.A.H.M.S. GMBHSTRUCK, Joachim
    • STRUCK, Joachim
    • G01N33/68C07K16/00
    • G01N33/566C07K16/26C07K2317/34G01N33/6893G01N2800/02G01N2800/06
    • The present invention relates to a method for the diagnosis, prognosis, monitoring and risk assessment of disturbances of the gastrointestinal tract activity and/or function and/or disturbances of the nutritional condition, with the exception of somatostatinoma, in a patient comprising the steps of: providing a sample of a bodily fluid of a patient; determining the level of proSomatostatin 1 -64 or fragments thereof in said sample; correlating the level of proSomatostatin 1 -64 or fragments thereof to the diagnosis, prognosis and risk assessment of disturbances of the gastrointestinal tract activity and/or function and/or disturbances of the nutritional condition, with the exception of somatostatinoma, in said patient, wherein said fragments have a length of at least 6 amino acid residues. The invention also relates to an antibody and a kit containing at least two antibodies.
    • 本发明涉及一种用于诊断,预后,监测和风险评估的方法,所述方法用于诊断,预后,监测和风险评估,所述方法包括以下步骤:在患者体内,除了生长激素抑制素之外,还包括以下步骤:胃肠道活动和/或功能和/或营养状况的紊乱 :提供患者的体液样品; 确定所述样品中促胰岛素抑制素1 -64或其片段的水平; 将所述患者中除促生长素抑制素1 -64或其片段的水平与除了生长抑素之外的胃肠道活动和/或功能和/或功能和/或紊乱的诊断,预后和风险评估相关联,其中 所述片段具有至少6个氨基酸残基的长度。 本发明还涉及含有至少两种抗体的抗体和试剂盒。
    • 9. 发明申请
    • METALLIC FLAT GASKET
    • 金属平板垫圈
    • WO2008128790A1
    • 2008-10-30
    • PCT/EP2008/003332
    • 2008-04-24
    • REINZ-DICHTUNGS-GMBHWALDVOGEL, JohannUNSELD, GuentherEGLOFF, GeorgHOEHE, Kurt
    • WALDVOGEL, JohannUNSELD, GuentherEGLOFF, GeorgHOEHE, Kurt
    • F16J15/08F02F11/00
    • F16J15/0818F16J15/0825F16J2015/085
    • The invention relates to a metallic flat gasket comprising two or more metallic gasket layers (2, 3, 3', 3"), of which a shortened gasket layer (2) has a smaller surface area than the at least one other gasket layer. At least one through-opening (4) extending through the gasket layers is surrounded by a self-contained bead (5) which is introduced into one of the relatively extensive gasket layers (3), the shortened gasket layer (2) leaving free an outer edge region (6), which does not comprise the bead (5), of the relatively extensive gasket layer. At least one structuring (7) is present in one of the gasket layers, in a region of the gasket in which the shortened gasket layer (2) is present or directly laterally adjoining this region adjacent to the position of the bead (5), said structuring protruding beyond at least one surface of the gasket layer and consisting of a large number of alternating elevations (31) and depressions (32) which are introduced into the gasket layer, the structuring (7) being present at least in certain portions in the circumferential direction around the through-opening (4).
    • 本发明涉及一种金属平垫圈,其包括两个或更多个金属垫圈层(2,3,3',3“),其中缩短的衬垫层(2)具有比至少一个其它衬垫层更小的表面积。 延伸穿过垫圈层的至少一个通孔(4)被引入到相对广泛的衬垫层(3)之一中的独立胎圈(5)包围,缩短的衬垫层(2) 至少一个结构(7)存在于一个垫圈层中,在垫圈的一个区域中,其中缩短了的边缘区域(6) 衬垫层(2)存在或直接横向邻接在该胎圈(5)的位置附近的该区域,所述结构突出超过衬垫层的至少一个表面,并由大量交替的高度(31)和凹陷 (32),其被引入到衬垫层中 至少在圆周方向上围绕通孔(4)至少存在一些部分(7)。