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1. 发明申请

WO2019032105A1 DISINTEGRIN VARIANTS AND USES THEREOF 审中-公开
公开(公告)号：WO2019032105A1
公开(公告)日：2019-02-14
申请号：PCT/US2017/046086
申请日：2017-08-09
申请人： NATIONAL TAIWAN UNIVERSTY , NATIONAL CHENG KUNG UNIVERSITY , DCB-USA LLC
发明人： HUANG, Tur-Fu , KUO, Yu-Ju , CHUANG, Woei-Jer
IPC分类号： C07K14/46 , C07K14/745 , C07K7/04 , C12N9/64
摘要： Disclosed herein are disintegrin variants, and methods for suppressing or inhibiting platelet aggregation in a subject in need thereof. The method includes administering to the subject in need thereof an effective amount of the present disintegrin variant to alleviate or ameliorate symptoms associated with diseases, disorders, and/or conditions resulted from platelet aggregation. According to preferred embodiments, the present disintegrain variant is applied as a coating on an implantable device, such as a stent or a catheter.

2. 发明申请

WO2014110245A1 SUSTAINED RELEASE FORMULATIONS OF LORAZEPAM 审中-公开
标题翻译： LORAZEPAM的持续释放配方
公开(公告)号：WO2014110245A1
公开(公告)日：2014-07-17
申请号：PCT/US2014/010854
申请日：2014-01-09
申请人： EDGEMONT PHARMACEUTICALS LLC
发明人： SALTEL, Douglas A. , VACHON, Michael
IPC分类号： A61K9/16 , A61K9/50 , A61K31/5513
CPC分类号： A61K9/5026 , A61K9/1652 , A61K9/4891 , A61K9/5047 , A61K9/5084 , A61K31/5513 , A61K47/36 , A61K47/38
摘要： A pharmaceutical composition for delivering lorazepam in a prolonged fashion is achieved with prolonged release lorazepam pharmaceutical beads. The composition typically contains sustained release lorazepam beads and delayed sustained release lorazepam beads. The composition can provide once daily dosing that maintains 24 hour therapeutic effect under steady state conditions.
摘要翻译：用延长释放的劳拉西泮药物珠粒实现长时间递送劳拉西泮的药物组合物。组合物通常含有持续释放的劳拉西泮珠和延迟的持续释放的劳拉西泮珠。该组合物可以每天一次给药，在稳态条件下维持24小时的治疗效果。

3. 发明申请

WO2006084081A2 DISPLAY WITH SELF-ILLUMINATABLE IMAGE AND METHOD FOR MAKING THE DISPLAY SUBSTRATE AND FOR MAKING THE IMAGE 审中-公开
标题翻译：具有自我照明图像的显示器和用于制作显示器基板并用于制作图像的方法
公开(公告)号：WO2006084081A2
公开(公告)日：2006-08-10
申请号：PCT/US2006/003755
申请日：2006-02-03
申请人： APPLETON COATED, LLC , BERY, Yuri, A. , OSTERBERG, Douglas, L.
发明人： BERY, Yuri, A. , OSTERBERG, Douglas, L.
IPC分类号： H01J9/227
CPC分类号： C09D11/52
摘要： A substrate has a self-illuminatable image. The substrate, which can be paper, will first receive conductive ink. The substrate can be calendered to provide a smooth, sealed surface for the ink. On top of the conductive ink, one or more dielectric layers can be provided followed by a phosphor-containing layer. A smoothing layer can then be provided. A second layer of conductive ink is provided on the smoothing layer. The conductive layers can be applied in any desired pattern. The first underlying conductive ink layer and the second overlying conductive ink layer will match the image in certain portions. When a current is passed through the conductive inks, phosphor in the phosphor-containing layer will be excited in order to illuminate the image. After printing of the first conductive layer, the substrate can be calendered to help connect conductive particles in the ink. A one-sided or two-sided display can be provided.
摘要翻译：基板具有可自发光的图像。可以是纸的基底将首先接收导电油墨。可以将基材压延以提供用于墨水的光滑，密封的表面。在导电油墨的顶部，可以提供一个或多个电介质层，随后是含荧光体层。然后可以提供平滑层。第二层导电油墨设在平滑层上。可以以任何期望的图案施加导电层。第一底层导电油墨层和第二覆盖导电油墨层将在某些部分匹配图像。当电流通过导电油墨时，含磷层的荧光体将被激发以照亮图像。在印刷第一导电层之后，可以将基底压延以帮助连接墨中的导电颗粒。可以提供单面或双面显示。

4. 发明申请

WO2003103795A3 VERTICALLY LAPPED FREE STANDING FILTER 审中-公开
公开(公告)号：WO2003103795A3
公开(公告)日：2003-12-18
申请号：PCT/US2003/018208
申请日：2003-06-11
申请人： LYDALL, INC. , HIERS, John, J.
发明人： HIERS, John, J.
IPC分类号： B01D27/06
摘要： A free standing filter (4) includes a non-woven material formed by vertical lapping of fibers to form a pleatedstructure. The non-woven material has decreased thickness portions (5-7) to increase the structural rigidity of the non-woven material. The free standing filter (4) is a frame free structure. The free standing filter (4) is manufactured by forming a non-woven material by vertical lapping of fibers to form a pleated structure.The non-woven material is then compressed to form decreased thickness portions (5-7) to increase thestructural rigidity of the non-woven material and avoid the necessity of a separate frame element. The decreased thickness portions (5-7) can be formed having a thickness slightly greater than a thickness of a support of a machine in which the free standing filter (4) is usable. Accordingly, the free standing filter (4) canbe a gasket free structure.

5. 发明申请

WO2021146521A1 A NOVEL CD16+ NATURAL KILLER CELL AND A METHOD OF CULTURING CD16+ NATURAL KILLER CELL 审中-公开
公开(公告)号：WO2021146521A1
公开(公告)日：2021-07-22
申请号：PCT/US2021/013577
申请日：2021-01-15
申请人： ACEPODIA BIOTECHNOLOGIES LTD. , ACEPODIA BIOTECH INC.
发明人： TANG, Sai-Wen , CHENG, Zih-Fei , LEE, Chia-Yun , LI, Hao-Kang , YANG, Hsiu-Ping , HSIAO, Ching-Wen , YANG, Sen Hen , WU, Tai-Sheng , LIN, Yan-Liang , LAI, Yan-Da , HSIAO, Shih-Chia
IPC分类号： C12N5/0783 , C07K16/28 , C07K16/32 , C07K14/705 , A61P35/00
摘要： The present invention provides a human CD16+ natural killer cell line and a CAR-expressing human CD16+ natural killer cell line. These human CD16+ natural killer cell line and a CAR-expressing human CD16+ natural killer cell line does not include synthetic, genetically modified or purposely deliberately delivered polynucleotide encoding the CD16 receptor and are non-tumorigenic cell lines. Therefore, this human CD16+ natural killer cell line and a CAR-expressing human CD16+ natural killer cell line might provide considerable long-term safety for disease treatment.

6. 发明申请

WO2020072809A1 METHOD AND APPARATUS FOR SURFACE PLASMON RESONANCE IMAGING 审中-公开
公开(公告)号：WO2020072809A1
公开(公告)日：2020-04-09
申请号：PCT/US2019/054553
申请日：2019-10-03
申请人： ACADEMIA SINICA , SHIH, Ming-Che
发明人： WEI, Pei-Kuen , PAN, Ming-Yang , LEE, Kuang-Li
IPC分类号： G01N21/55 , G01N21/17 , G01N21/41 , G01N21/62
摘要： A method and apparatus for surface plasmon resonance imaging are provided for imaging the surface plasmon resonance signals caused by the interaction of biomolecules. In particular, the method and apparatus can image the slightly spectral change in a surface plasmon resonance mode by comparing the light intensities of two bands in the frequency domain of the surface plasmon.

7. 发明申请

WO2012006285A1 METHOD FOR QUANTIFYING AND ANALYZING INTRINSIC PARALLELISM OF AN ALGORITHM 审中-公开
标题翻译：定量分析算法的内在平行方法
公开(公告)号：WO2012006285A1
公开(公告)日：2012-01-12
申请号：PCT/US2011/042962
申请日：2011-07-05
申请人： LEE, Gwo-Giun Chris , LIN, He-Yuan , NATIONAL CHENG KUNG UNIVERSITY
发明人： LEE, Gwo-Giun Chris , LIN, He-Yuan
IPC分类号： G06F9/44
CPC分类号： G06F17/10 , G06F8/456 , G06F17/147
摘要： A method for quantifying and analyzing intrinsic parallelism of an algorithm is adapted to be implemented by a computer, and includes the steps of: configuring the computer to represent the algorithm by means of a plurality of operation sets; configuring the computer to obtain a Laplacian matrix according to the operation sets; configuring the computer to compute eigenvalues and eigenvectors of the Laplacian matrix; and configuring the computer to obtain a set of information related to intrinsic parallelism of the algorithm according to the eigenvalues and the eigenvectors of the Laplacian matrix.
摘要翻译：一种用于量化和分析算法的本征并行度的方法适于由计算机实现，并且包括以下步骤：配置计算机以通过多个操作集来表示算法; 配置计算机根据操作集获得拉普拉斯矩阵; 配置计算机来计算拉普拉斯矩阵的特征值和特征向量; 以及配置计算机以获得与根据拉普拉斯矩阵的特征值和特征向量的算法的本征并行度相关的一组信息。

8. 发明申请

WO2004007257A2 DRIVESHAFT BRAKE ASSEMBLY 审中-公开
标题翻译： DRIVESHAFT制动总成
公开(公告)号：WO2004007257A2
公开(公告)日：2004-01-22
申请号：PCT/US2003/022285
申请日：2003-07-16
申请人： BECK, Roy
发明人： BECK, Roy
IPC分类号： B60T
CPC分类号： B60T10/00 , B60T1/062 , F16D49/00 , F16D2121/02 , F16D2125/14 , F16D2125/582
摘要： A driveline brake assembly for use on trucks as either a primary braking system or a secondary braking system. A camshaft connected to the driveline carries a number of cams thereon. Each cam has associated therewith a pair of pressure glides which ride on the cam from opposite sides. Each pressure glide may be forced against the cam forcibly due to an inflated air bladder pressing compression springs against the back of the pressure glide. This forcible pushing of the glides against the cams causes the camshaft to slow its rotational speed and accordingly slow the truck.
摘要翻译：用于卡车的传动系制动器组件，作为主制动系统或二次制动系统。连接到传动系统的凸轮轴在其上携带多个凸轮。每个凸轮与其相关联地具有一对从相对侧骑在凸轮上的压力滑移。由于充气气囊压靠压力滑行背面的压缩弹簧，每个压力滑行可能被强制地抵靠凸轮。这种强制推动滑轮的凸轮导致凸轮轴减速其转速并相应地使卡车减速。

9. 发明申请

WO2002098382A1 THERMALLY INSULATING INTERFACES 审中-公开
标题翻译：绝热绝缘
公开(公告)号：WO2002098382A1
公开(公告)日：2002-12-12
申请号：PCT/US2002/017823
申请日：2002-06-06
申请人： NL TECHNOLOGIES, LTD.
发明人： NEWBERG, Douglas A.
IPC分类号： A61K7/13
CPC分类号： F16K49/00 , F16K27/07 , F16K49/005 , Y10T137/6579 , Y10T137/6606 , Y10T137/7036
摘要： At least one of a valve body (29), a sealing tip (25), and a vessel or conduit (10) includes at least one space (5) formed therein between an interior of the vessel or conduit (10) and an internal cavity (23) of the valve (13). The space (5) includes an active or passive thermal insulation (7) forming at least a partial barrier to the flow of heat between the internal cavity (23) and the interior of the vessel or conduit (10).
摘要翻译：阀体（29），密封末端（25）和容器或管道（10）中的至少一个包括在容器或管道（10）的内部和内部（10）之间形成的至少一个空间（5）阀（13）的腔（23）。所述空间（5）包括主动或被动热绝缘（7），其形成至少部分阻挡所述内部空腔（23）与所述容器或导管（10）内部之间的热量的流动。

10. 发明申请

WO2002095111A1 VERTICALLY LAPPED MATERIAL FOR ACOUSTIC APPLICATIONS 审中-公开
标题翻译：用于声学应用的垂直材料
公开(公告)号：WO2002095111A1
公开(公告)日：2002-11-28
申请号：PCT/US2002/016065
申请日：2002-05-23
申请人： LYDALL, INC. , ATTKISSON, William, C. , FLETCHER, John, K.
发明人： ATTKISSON, William, C. , FLETCHER, John, K.
IPC分类号： D04H5/06
CPC分类号： D04H1/54 , B60N3/048 , D04H1/4374 , D04H1/498 , D04H1/74 , G10K11/168
摘要： A vertically lapped material for acoustic applications includes a first layer of material constructed from at least one layer of non-woven textile fibers. The at least one layer of non-woven textile fibers is folded into a plurality of folds to form a pleated structure. A depth of the pleats of the pleated structure determines a thickness of the first layer of material. Furthermore, at least one second layer of material is connected to the at least one first layer of material. A method of assembling a carpet to form a carpet assembly includes the steps of providing the above at least one first layer of material and a heated carpet; inserting the at least one layer in a cold mold adjacent to the heated carpet; and molding the at least one layer with the heated carpet in the cold mold to form the carpet assembly. It is unnecessary for the at least one layer to be preheated or premolded before insertion into the cold mold.
摘要翻译：用于声学应用的垂直搭接材料包括由至少一层非织造纺织纤维构成的第一层材料。将至少一层无纺织物纤维折叠成多个褶皱以形成褶皱结构。折叠结构的褶皱的深度确定第一层材料的厚度。此外，至少一个第二层材料连接到该至少一个第一材料层。一种组装地毯以形成地毯组件的方法包括以下步骤：提供上述至少一个第一材料层和加热地毯; 将所述至少一个层插入与加热的地毯相邻的冷模具中; 以及在所述冷模具中将所述加热的地毯模制所述至少一层以形成所述地毯组件。在插入冷模具之前，不需要将至少一层预热或预先加工。

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