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    • 9. 发明申请
    • A FAST MICROSCOPE FOR MEASURING DYNAMIC OPTICAL SIGNALS
    • 用于测量动态光学信号的快速显微镜
    • WO2013184918A1
    • 2013-12-12
    • PCT/US2013/044515
    • 2013-06-06
    • THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    • SHTRAHMAN, MatthewAHARONI, Daniel
    • G02B21/00G01N21/64
    • G02B21/002G01N21/6408G01N21/6458G01N2201/0675G02B21/16G02B21/32G02B21/365
    • In one embodiment, a method includes instructing a pattern generator to provide an excitation pattern to a sample under test, and controlling a movable mechanism that receives an emission pattern from the sample under test responsive to the excitation pattern. The controlling includes causing the movable mechanism to sweep a representation of the emission pattern along a path, thereby creating at least one streak, and synchronizing the motion of the movable mechanism with the frame rate of an imaging device, such that a full sweep of the representation of the emission pattern along the path corresponds to approximately one frame of the imaging device. The variable intensity of each streak represents a corresponding time varying intensity of a portion of the emission pattern. The varying intensity of a portion of the emission pattern may be captured with sub-millisecond resolution.
    • 在一个实施例中,一种方法包括指示图案发生器向被测试样品提供激励图案,以及控制响应于激发图案从被测样品接收发射图案的可移动机构。 该控制包括使可移动机构沿着路径扫描发射图案的表示,从而产生至少一条条纹,并使可移动机构的运动与成像装置的帧速率同步,使得全扫描 沿着路径的发射图案的表示对应于成像装置的大约一帧。 每个条纹的可变强度表示发射图案的一部分的对应的时变强度。 可以以亚毫秒分辨率捕获发射图案的一部分的变化强度。