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    • 1. 发明申请
    • POSITION-DEFINED CELL CULTURE AND CHARACTERIZATION PLATFORM
    • 位置定义细胞培养和表征平台
    • WO2016112344A1
    • 2016-07-14
    • PCT/US2016/012736
    • 2016-01-08
    • THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    • LO, Yu-HwaCHIU, Yu, Jui (Roger)CAI, Wei
    • C12Q1/68
    • G01N33/56966C12M47/04G01N33/54366
    • Methods, systems, and devices are disclosed for culturing and characterizing individual cellular entities including cells, organoids, or tissue. In one aspect, a device includes a first substrate structured to include an array of hydrophilic regions surrounded by a hydrophobic surface including nanostructures protruding from the hydrophobic surface, in which the array of hydrophilic regions are capable to adhere an individual cellular entity and the hydrophobic surface is configured to prevent the cellular entity from adherence; and a second substrate including a coating of antibodies corresponding to a type of cellular substance secreted by the cellular entity, in which the second substrate is operable to be placed upon the first substrate such that the coating of antibodies makes contact with the individual cellular entities adhered to the hydrophilic regions.
    • 公开了用于培养和表征包括细胞,组织或组织在内的个体细胞实体的方法,系统和装置。 在一个方面,一种装置包括第一衬底,其被构造成包括由疏水表面包围的亲水区域阵列,所述疏水表面包括从疏水表面突出的纳米结构,其中所述亲水区域阵列能够粘附单个细胞体和所述疏水表面 被配置为防止蜂窝实体遵守; 以及第二底物,其包含对应于由细胞实体分泌的细胞物质类型的抗体包被,其中第二底物可操作地置于第一底物上,使得抗体包被与附着的各个细胞体接触 到亲水区域。
    • 4. 发明申请
    • NON-INVASIVE IN-SITU IMAGING OF INTERIOR OF NUCLEAR REACTORS
    • 核反应堆内部非侵入式现场成像
    • WO2015153801A1
    • 2015-10-08
    • PCT/US2015/023936
    • 2015-04-01
    • LOS ALAMOS NATIONAL SECURITY, LLC
    • MILNER, Edward, CasteelBOROZDIN, Konstantin, N.MORRIS, Christopher, L.MIYADERA, HaruoPERRY, John, Oliver
    • G21C17/06G21C17/10
    • G21C17/06G01N23/04G01N23/203G01N2223/625G21C17/003G21C17/08
    • Techniques, systems, and devices are disclosed for non-invasive monitoring and imaging of nuclear fuel inside a nuclear reactor using muon detector arrays. In one aspect, these detector arrays are placed outside the reactor vessel or building for investigating the reactors without access to the cores, therefore the imaging process is non-invasive. In some implementation, these detector arrays measure both muon scattering and absorption to enable imaging and characterizing not only the very high-Z fuel materials, but also other materials in the reactor, thereby obtaining a more complete picture of reactor status. When applied to damaged reactors, the disclosed proposed techniques, systems, and devices, through the process of providing an image, can reveal the presence (or absence) of damage to fuel rod assemblies or puddles of molten fuel at the bottom of the containment vessel, thus providing crucial information to guide decisions about remedial actions.
    • 公开了用于使用μ子探测器阵列在核反应堆内对核燃料进行非侵入性监测和成像的技术,系统和装置。 在一个方面,将这些检测器阵列放置在反应器容器或建筑物的外部,用于调查反应器而不进入核心,因此成像过程是非侵入性的。 在一些实施方案中,这些检测器阵列测量了μon散射和吸收,以便能够成像和表征非常高的Z燃料材料,以及反应器中的其他材料,从而获得反应器状态的更完整的图像。 当应用于损坏的反应堆时,所公开的技术,系统和装置,通过提供图像的过程,可以揭示在安全壳底部的燃料棒组件或熔融燃料的水坑的存在(或不存在) ,从而提供重要的信息来指导有关补救行动的决定。
    • 7. 发明申请
    • MAGNETOENCEPHALOGRAPHY SOURCE IMAGING FOR NEUROLOGICAL FUNCTIONALITY CHARACTERIZATIONS
    • 用于神经功能特征的磁感应成像
    • WO2015021070A1
    • 2015-02-12
    • PCT/US2014/049824
    • 2014-08-05
    • THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    • HUANG, Ming-XiongLEE, Roland, R.
    • A61B5/05
    • A61B5/04008A61B5/04009A61B5/055A61B5/7203A61B5/7235
    • Methods, systems, and devices are disclosed for implementing magnetoencephalography (MEG) source imaging. In one aspect, a method includes determining a covariance matrix based on sensor signal data in the time domain or frequency domain, the sensor signal data representing magnetic-field signals emitted by a brain of a subject and detected by MEG sensors in a sensor array surrounding the brain, defining a source grid containing source locations within the brain that generate magnetic signals, the source locations having a particular resolution, in which a number of source locations is greater than a number of sensors in the sensor array, and generating a source value of signal power for each location in the source grid by fitting the selected sensor covariance matrix, in which the covariance matrix is time-independent based on time or frequency information of the sensor signal data.
    • 公开了用于实现脑磁图(MEG)源成像的方法,系统和装置。 一方面,一种方法包括基于时域或频域中的传感器信号数据来确定协方差矩阵,所述传感器信号数据表示由对象的脑发射并由传感器阵列中的MEG传感器检测的磁场信号 大脑,定义包含产生磁信号的大脑内的源位置的源网格,源位置具有特定分辨率,其中多个源位置大于传感器阵列中的多个传感器,并且产生源值 通过拟合所选择的传感器协方差矩阵,其中协方差矩阵是基于传感器信号数据的时间或频率信息而与时间无关的信号功率。
    • 8. 发明申请
    • GAMMA PROBE WITH HAND-PIECE CONTROL OF DETECTION PARAMETERS
    • 具有检测参数的手柄控制的游戏探头
    • WO2015003020A1
    • 2015-01-08
    • PCT/US2014/045165
    • 2014-07-01
    • COKIYA, INC.
    • YARNALL, Stephen, T.KINDEM, JoelCONWELL, Richard, L.
    • A61B19/00G01T1/161
    • G01T1/161A61B6/12A61B6/4057A61B6/4258A61B6/4405A61B6/46A61B6/54
    • Apparatus, techniques and systems are described for facilitating identification of a target area during a probe-guided radio-localization surgical procedure. The described apparatus, techniques and systems can be used to implement a nuclear-uptake mode controller integrated into a probe to allow a user to instantly switch between multiple nuclear- uptake modes directly from the probe hand-piece. For example, a nuclear-uptake mode controller integrated into the probe can be used to instantly switch between a high-sensitivity nuclear-uptake mode and a high-resolution nuclear-uptake mode to effectively identify the target area in the presence of interfering nuclear signals by better matching the probe's nuclear detection parameters to a search task for that target area.
    • 描述了用于在探针引导的无线电定位外科手术期间便于识别目标区域的装置,技术和系统。 所描述的装置,技术和系统可用于实现集成到探针中的核吸收模式控制器,以允许用户直接从探针手段在多个核摄取模式之间立即切换。 例如,集成到探头中的核吸收模式控制器可用于在高灵敏度核摄取模式和高分辨率核摄取模式之间立即切换,以在存在干扰核信号的情况下有效识别目标区域 通过更好地将探测器的核检测参数与该目标区域的搜索任务相匹配。
    • 9. 发明申请
    • MOBILE HANDSET FOR MEDIA ACCESS AND PLAYBACK
    • 媒体访问和播放的移动手机
    • WO2011156783A2
    • 2011-12-15
    • PCT/US2011/040086
    • 2011-06-10
    • CRICKET COMMUNICATIONS, INC.CASSIDY, Brendon, P.
    • CASSIDY, Brendon, P.
    • G06Q50/00G06F15/16G11B20/10G11B27/10H04W4/00
    • H04W4/20G11B27/102G11B27/11G11B27/34H04L67/1095H04W4/21
    • Methods, systems, and apparatus are presented for accessing unlimited media service from a mobile communications device. A media server environment can be provided, which maintains an instance of each subscriber account and a central archive of media content. Further, the central archive can be explored through the use of a media application executed on a mobile communications device to select media content, including individual items of media content, playlists, ringtones, and ringback tones. The selected media content can be downloaded to, and stored locally at, the mobile communications device, such as on a secure storage device. Additionally, media content corresponding to a subscribed playlist can be automatically updated at the mobile communications device in response to changes to the playlist.
    • 呈现用于从移动通信设备访问无限媒体服务的方法,系统和装置。 可以提供媒体服务器环境,其维护每个订户帐户的实例和媒体内容的中央归档。 此外,可以通过使用在移动通信设备上执行的媒体应用来选择媒体内容,包括媒体内容的单个项目,播放列表,铃声和回铃音来探索中央归档。 所选择的媒体内容可以被下载到移动通信设备本地并存储在诸如安全存储设备上的移动通信设备上。 此外,响应于播放列表的改变,可以在移动通信设备处自动更新与订阅的播放列表相对应的媒体内容。