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    • 3. 发明申请
    • ELECTROCHEMICAL TEST STRIP
    • 电化学测试条
    • WO2009015077A1
    • 2009-01-29
    • PCT/US2008/070630
    • 2008-07-21
    • AGAMATRIX, INC.HARDING, IanIYENGAR, Sridhar
    • HARDING, IanIYENGAR, Sridhar
    • C12M1/34C12Q1/00G01N33/487G01N27/327
    • G01N27/3272C12Q1/001
    • An electrochemical test strip is formed from a first insulating substrate layer, a second substrate layer, and an intervening insulating spacer layer. An opening in the insulating spacer layer defines a test cell which is in contact with the inner surface of the first substrate on one side and the inner surface of the second substrate on the other side. The size of the test cell is determined by the area of substrate exposed and the thickness of the spacer layer. Working and counter electrodes appropriate for the analyte to be detected are disposed on the first insulating substrate in a location within the test cell. The working and counter electrodes are associated with conductive leads that allow connection of the electrodes to a meter for dertermination of analyte. The second substrate is conductive at least in a region facing the working and counter electrodes. No functional connection of this conductive surface of the second substrate to the meter is required. When a potential difference is applied between the working and counter electrodes, because of the presence of the conductive surface on the second substrate, the relevant diffusion length is not dependent on the distance between working and counter electrodes, but is instead dependent on the distance between the first and second substrates (i.e., on the thickness of the spacer layer). This means that shorter measurement times can be achieved without having to reduce the spacing of the working and counter electrodes.
    • 电化学测试条由第一绝缘衬底层,第二衬底层和中间绝缘间隔层形成。 绝缘间隔层中的开口限定了与第一基板的内表面和另一侧的第二基板的内表面接触的测试单元。 测试电池的尺寸由衬底暴露的面积和间隔层的厚度决定。 适于待检测分析物的工作和对电极在测试电池内的一个位置设置在第一绝缘衬底上。 工作电极和对电极与导电引线相关联,导电引线允许将电极连接到用于测定分析物的仪表。 至少在面向工作电极和对电极的区域中,第二衬底是导电的。 不需要将第二基板的该导电表面与仪表的功能连接。 当在工作电极和对电极之间施加电位差时,由于在第二衬底上存在导电表面,相关的扩散长度不依赖于工作电极和对电极之间的距离,而是取决于 第一和第二基板(即,在间隔层的厚度上)。 这意味着可以实现更短的测量时间,而不必减小工作电极和对电极的间隔。