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81. 发明申请

WO2007136489A2 MULTIPLE LEVEL SECURITY ADAPTER 审中-公开
标题翻译：多级安全适配器
公开(公告)号：WO2007136489A2
公开(公告)日：2007-11-29
申请号：PCT/US2007/009668
申请日：2007-04-18
申请人： THE BOEING COMPANY , BALZA, Richard, M. , UNG, Kevin, Y. , ARNOLD, Steven, L. , DONOFRIO, Thomas, E. , MURPHY, Michael, J. , HARTMAN, Brett , KWOK, Samuel, C.
发明人： BALZA, Richard, M. , UNG, Kevin, Y. , ARNOLD, Steven, L. , DONOFRIO, Thomas, E. , MURPHY, Michael, J. , HARTMAN, Brett , KWOK, Samuel, C.
CPC分类号： H04L63/105 , H04L69/08
摘要： In exemplary embodiments, data with a format compatible with a first protocol standard is received on behalf of a first application. When the format of the data is not compatible with a second protocol standard, the format of the data is automatically transformed to a format that is compatible with the second protocol standard. The data is transmitted to a second application service using the second protocol standard. The data may be received from the second application. When the format of the data is not compatible with a third protocol standard, the format of the data is automatically transformed to a format that is compatible with the third protocol standard. The data is transmitted on behalf of a third application using the third protocol standard. The first and third applications may be in first and second protected enclaves. The second application may include a security gateway service.
摘要翻译：在示例性实施例中，代表第一应用接收具有与第一协议标准兼容的格式的数据。当数据的格式与第二协议标准不兼容时，数据的格式将自动转换为与第二协议标准兼容的格式。使用第二协议标准将数据发送到第二应用服务。可以从第二应用接收数据。当数据格式与第三协议标准不兼容时，数据的格式将自动转换为与第三协议标准兼容的格式。使用第三协议标准代表第三应用发送数据。第一和第三种应用可能在第一和第二受保护的飞地。第二应用可以包括安全网关服务。

82. 发明申请

WO2007104371A1 APPARATUS AND METHOD FOR SEALING A LIDSTOCK TO A CONTAINER 审中-公开
标题翻译：用于将集装箱密封到集装箱的装置和方法
公开(公告)号：WO2007104371A1
公开(公告)日：2007-09-20
申请号：PCT/EP2006/070117
申请日：2006-12-21
申请人： BAUSCH & LOMB INCORPORATED , O'NEILL, Trevor, F. , O'NEILL, Anthony , MURPHY, Michael, W. , TOBIN, Patrick, J. , COPPINGER, John, R. , O'NEILL, Patrick, D.
发明人： O'NEILL, Trevor, F. , O'NEILL, Anthony , MURPHY, Michael, W. , TOBIN, Patrick, J. , COPPINGER, John, R. , O'NEILL, Patrick, D.
IPC分类号： B65B7/28 , B65D77/20
CPC分类号： B65B7/2878 , B29C65/18 , B29C65/305 , B29C65/76 , B29C66/112 , B29C66/131 , B29C66/21 , B29C66/242 , B29C66/244 , B29C66/301 , B29C66/30223 , B29C66/3452 , B29C66/53461 , B29C66/71 , B29C66/72321 , B29C66/81415 , B29C66/81429 , B29C66/8167 , B29C66/8221 , B29C66/8242 , B29C66/8246 , B29C66/8324 , B29C66/8432 , B29C66/91212 , B29C66/91231 , B29C66/924 , B29C66/944 , B29L2011/0041 , B29L2031/712 , B65D77/2032 , B65D2585/545 , B29K2023/12
摘要： The invention relates to a method for heat sealing a lidstock (9) to a container (1) for a blister package, the container having a top surface comprising a substantially flat sealing flange (3) surrounding a blister (2) and a lip (4) having at least one raised surface (6) , the method comprising the steps of a) locating the lidstock on the top surface; b) providing a first seal between the lidstock and the at least one raised surface of the lip with a first heat sealing tool (11) ; c) providing a second hermetic seal between the lidstock and the sealing flange surrounding the blister with a second heat sealing tool. The invention also relates to a package for storing a hydrophilic contact lens comprising a lip having at least one raised surface and a removable lidstock sealed to a sealing flange and to the at least one raised surface. Also disclosed is an apparatus for heat sealing the lidstock to the container.
摘要翻译：本发明涉及一种用于将盖子（9）热封到用于泡罩包装的容器（1）的方法，该容器具有顶表面，该顶表面包括围绕泡罩（2）和唇缘（2）的基本平坦的密封凸缘（3） 4）具有至少一个凸起表面（6），所述方法包括以下步骤：a）将盖子定位在顶部表面上; b）用第一热封工具（11）在盖子和唇缘的至少一个凸起表面之间提供第一密封; c）利用第二热封工具在所述盖子和围绕所述泡罩的所述密封凸缘之间提供第二密封。本发明还涉及用于存储亲水接触透镜的包装，其包括具有至少一个凸起表面的唇缘和密封到密封凸缘和至少一个凸起表面的可移除盖子。还公开了一种用于将盖子热封到容器的装置。

83. 发明申请

WO2007097884A1 A METHOD FOR GENERATING REFERENCE CONTROLS FOR PHARMACOGENOMIC TESTING 审中-公开
标题翻译：一种用于产生药物生物学测试参考控制的方法
公开(公告)号：WO2007097884A1
公开(公告)日：2007-08-30
申请号：PCT/US2007/002487
申请日：2007-01-29
申请人： GENTRIS CORPORATION , MURPHY, Michael, P. , CLARK, L., Scott. , NAHKLE, Pamela, J. , BUTZ, Kenneth, G.
发明人： MURPHY, Michael, P. , CLARK, L., Scott. , NAHKLE, Pamela, J. , BUTZ, Kenneth, G.
IPC分类号： C12N15/29 , C12N15/09 , C12N15/10
CPC分类号： C12N5/0635 , C12N2503/00 , C12N2510/04
摘要： Reference controls for use with pharmacogenomic testing, and methods for their identification, preparation, and use, are disclosed. The reference controls can confirm that pharmacogenomic testing correctly identifies individuals that do or do not have the mutation of interest, in both clinical trial and patient treatment settings. The reference controls can be selected to include one or more mutations to be identified, and prescreened to confirm that they bind to one or more of the primers used in the pharmacogenomic testing. The reference controls are human genomic DNA that includes certain identified polymorphisms (mutations) of interest, ideally derived from individuals, pre-selected and optionally properly consented, which have one or more of the polymorρhism(s) of interest. The reference controls can be prepared by targeted pre-screening of human patients, by examining the genotype or genetic profile of the patients, isolating cells with the desired mutation, optionally immortalizing the cells, and obtaining DNA from the cells. The prescreening of prospective donors can be targeted based on any of a number of factors, such as genes of interest, mutations within the genes of interest, and membership in a specific ethnic or disease state population. The genomic DNA can be pre-screened for its ability to be detected, using a standard pharmacogenomic test, as including a specific mutation. Examples of mutations of interest include those present in a Phase I or Phase II metabolic enzyme such as CYP2D6, CYP2C19, CYP2C9, CYP2C8, and CYP3A5, CYP3A4, CYP2A6, CYP2B6, UGTlAl, DPD, ERCCl, MDRl, ADH2, NATl and NAT2 or any other metabolic or disease gene.
摘要翻译：公开了用于药物基因组测试的参考对照及其鉴定，制备和使用的方法。在临床试验和患者治疗环境中，参照对照可以证实药物基因组检测正确地识别出有或没有感兴趣突变的个体。可以选择参考对照以包括待鉴定的一个或多个突变，并进行预筛选以确认它们与药物基因组测试中使用的一种或多种引物结合。参考对照是人类基因组DNA，其包括某些鉴定的感兴趣的多态性（突变），理想地衍生自预先选择的和任选正确同意的个体，其具有一种或多种感兴趣的多形性。通过检查患者的基因型或遗传特征，分离具有所需突变的细胞，任选地使细胞永生化，以及从细胞获得DNA，可以通过目标预筛选人类患者来制备参照对照。预期供体的预筛选可以基于许多因素，如感兴趣的基因，感兴趣的基因内的突变和特定种族或疾病状态群体的成员中的任何一个来定位。可以使用标准药物基因组测试将基因组DNA的筛选能力进行预筛选，作为包括特异性突变。感兴趣的突变的实例包括存在于I期或II期代谢酶如CYP2D6，CYP2C19，CYP2C9，CYP2C8和CYP3A5，CYP3A4，CYP2A6，CYP2B6，UGT1A1，DPD，ERCC1，MDR1，ADH2，NAT1和NAT2中的那些，任何其他代谢或疾病基因。

84. 发明申请

WO2007075153A2 DECONTAMINANT 审中-公开
标题翻译：去污剂
公开(公告)号：WO2007075153A2
公开(公告)日：2007-07-05
申请号：PCT/US2005041714
申请日：2005-11-14
申请人： BATTELLE MEMORIAL INSTITUTE , MONZYK BRUCE F , GREENE RUSSELL R , CUCKSEY CHAD M , MCARTHUR JOHN A , VON FAHNESTOCK F MICHAEL , LORENCE STEVEN C , MURPHY MICHAEL J , BLACKSTONE BRIAN J , MALLOY THOMAS A IV
发明人： MONZYK BRUCE F , GREENE RUSSELL R , CUCKSEY CHAD M , MCARTHUR JOHN A , VON FAHNESTOCK F MICHAEL , LORENCE STEVEN C , MURPHY MICHAEL J , BLACKSTONE BRIAN J , MALLOY THOMAS A IV
CPC分类号： A62D3/38 , A62D2101/02 , A62D2101/04 , A62D2101/24 , A62D2101/26 , A62D2101/28 , A62D2101/43 , Y02W10/37
摘要： Method and composition for decomposing and detoxifying chemical warfare agents, organic toxic compounds (e. g., pesticides), and for removal of contaminants in materials including fuels. The method and composition are based on ferrate (VI). The ferrate is typically applied to a contaminated surface or volume with a phase transfer catalyst and/or with a carrier.
摘要翻译：用于分解和解毒化学战剂，有机毒性化合物（例如杀虫剂）以及用于去除包括燃料的材料中的污染物的方法和组合物。该方法和组成基于高铁酸盐（VI）。高铁酸盐通常用相转移催化剂和/或载体应用于受污染的表面或体积。

85. 发明申请

WO2006042131A3 PERFORATION ALIGNEMENT TOOL FOR JET DRILLING, PERFORATING AND CLEANING 审中-公开
标题翻译：喷射钻孔，执行和清洁的执行对准工具
公开(公告)号：WO2006042131A3
公开(公告)日：2007-05-31
申请号：PCT/US2005036199
申请日：2005-10-06
申请人： BUCKMAN JET DRILLING INC , MALONE PHILIP G , MURPHY MICHAEL E , BRISCOE FLOYD H , BUCKMAN WILLIAM G SR , HALE CARL B , SEARS ADAM W
发明人： MALONE PHILIP G , MURPHY MICHAEL E , BRISCOE FLOYD H , BUCKMAN WILLIAM G SR , HALE CARL B , SEARS ADAM W
IPC分类号： E21B43/11 , E21B43/26
CPC分类号： E21B43/114 , E21B7/061 , E21B7/18 , E21B17/07 , E21B37/08 , E21B43/119 , E21B47/09
摘要： Method and apparatus are provided for pumping operations that may be used to form perforations in the casing of a well, clean perforations and drill drain holes through perforations. A plunger is placed in a reference perforation and the pumping operations may be performed through a nozzle at a known location with respect to the reference perforation. The nozzle may be attached to a flexible hose to drill a drain hole or may be inserted in a body on the bottom of a tubing string. Addition apparatus and method are provided to insure that the plunger or plungers are maintained in a reference perforation or perforations when pumping operations are carried out through tubing.
摘要翻译：提供了用于泵送操作的方法和装置，其可用于在井的壳体中形成穿孔，通过穿孔的清洁穿孔和钻孔排放孔。柱塞被放置在参考穿孔中，并且泵送操作可以通过相对于参考穿孔的已知位置处的喷嘴进行。喷嘴可以附接到柔性软管以钻出排水孔，或者可以插入管柱底部的主体中。提供添加装置和方法以确保当泵送操作通过管道执行时柱塞或柱塞保持在参考穿孔或穿孔中。

86. 发明申请

WO2006017328A3 TRANSIENT PROTECTOR CIRCUIT FOR MULTI-PHASE ENERGIZED POWER SUPPLIES 审中-公开
标题翻译：多相电源的瞬态保护电路
公开(公告)号：WO2006017328A3
公开(公告)日：2006-07-13
申请号：PCT/US2005024804
申请日：2005-07-13
申请人： ELSTER ELECTRICITY LLC , MURPHY MICHAEL A
发明人： MURPHY MICHAEL A
IPC分类号： H02H3/22
CPC分类号： H02H9/04
摘要： Circuits and systems are used in multi-phase power supplies for the prevention of transient currents. Phase to phase and phase to neutral metal oxide varistors ("MOV") are replaced with a single DC power supply connected MOV. Transient currents are limited by resistors that are connected in series to each of the three phase inputs. Comprising a single DC connected MOV, protection from transients between any of the four inputs is provided. The phase to phase and the phase to neutral transient currents are routed, using diodes, through a single MOV connected between the positive and negative input terminals of the DC power supply.
摘要翻译：电路和系统用于防止瞬态电流的多相电源。相间和相线到中性金属氧化物压敏电阻（“MOV”）被替换为连接MOV的单个直流电源。瞬态电流受到与三相输入端串联的电阻器的限制。包括一个直流连接的MOV，提供四路输入之间的瞬态保护。通过连接在直流电源的正极和负极输入端子之间的单个MOV，使用二极管将相间和相间中性瞬态电流进行路由。

87. 发明申请

WO2005100959A1 INSPECTION SYSTEM FOR BLISTER PACKAGES 审中-公开
标题翻译：检验包装检验系统
公开(公告)号：WO2005100959A1
公开(公告)日：2005-10-27
申请号：PCT/US2005/009510
申请日：2005-03-22
申请人： BAUSCH & LOMB INCORPORATED , BARRY, Paud , MURPHY, Michael, W. , ROCHE, Eoin
发明人： BARRY, Paud , MURPHY, Michael, W. , ROCHE, Eoin
IPC分类号： G01N21/84
CPC分类号： B07C5/3422 , B65B25/008 , G01N21/9054 , G01N21/9508
摘要： An inspection system for inspecting the seal area and/or volume fill level of a blister package comprising an image pick-up device and providing an image pick-up device; presenting the blister package with cover adhered thereto to the field of view of said image pick-up device; imaging and determining the grey level of said seal area and comparing the imaged grey level to a predetermined grey level value; and passing the blister package inspection if the imaged grey level is substantially the same as the predetermined grey level value or rejecting the blister package inspection is the imaged grey level is not substantially the same as the predetermined grey level value.
摘要翻译：一种用于检查包括图像拾取装置并提供图像拾取装置的泡罩包装的密封区域和/或体积填充水平的检查系统; 将具有附着到其上的盖的泡罩包装呈现在所述图像拾取装置的视场中; 成像并确定所述密封区域的灰度级并将成像的灰度级与预定的灰度值进行比较; 并且如果成像的灰度级与预定的灰度值基本相同或拒绝泡罩包装检查，则通过泡罩包装检查，成像的灰度级与预定的灰度值基本上不相同。

88. 发明申请

WO2005035546A1 PEPTIDE NUCLEIC ACID CONJUGATES AND USES THEREOF 审中-公开
标题翻译：肽类核酸结合物及其用途
公开(公告)号：WO2005035546A1
公开(公告)日：2005-04-21
申请号：PCT/NZ2004/000255
申请日：2004-10-15
申请人： UNIVERSITY OF OTAGO , ECCLES, Roger, Michael, , MURATOVSKA, Aleksandra , SMITH, Robin, A., J. , MURPHY, Michael, Patrick
发明人： ECCLES, Roger, Michael, , MURATOVSKA, Aleksandra , SMITH, Robin, A., J. , MURPHY, Michael, Patrick
IPC分类号： C07H21/00
CPC分类号： C12N15/113 , A61K38/00 , A61K47/64 , C07F9/5407 , C07F9/5442 , C07K14/003 , C12N15/111 , C12N2310/11 , C12N2310/3181 , C12N2310/351 , C12N2320/32
摘要： The invention provides a triphenylphosphonium peptide nucleic acid conjugate. The conjugate comprises a peptide nucleic acid linked via a disulfide bond, to a triphenylphosphonium group. Conjugates of the invention can be used to deliver PNA oligomers across the plasma membrane into cells.
摘要翻译：本发明提供三苯基鏻肽核酸缀合物。缀合物包含通过二硫键连接的肽核酸与三苯基鏻基团。本发明的缀合物可以用于将PNA寡聚物跨过质膜递送到细胞中。

89. 发明申请

WO2003032110A2 SYTEM FOR COMBINING POSTAGE, MAILING ADDRESS INFORMATION, AND PAYMENT SERVICES 审中-公开
标题翻译：组合邮寄，邮寄地址信息和付款服务的SYTEM
公开(公告)号：WO2003032110A2
公开(公告)日：2003-04-17
申请号：PCT/US2002/030703
申请日：2002-09-27
申请人： THE ESCHER GROUP, LTD. , MURPHY, Michael, J. , SMITH, Joshua, R. , YARIN, Paul, M.
发明人： MURPHY, Michael, J. , SMITH, Joshua, R. , YARIN, Paul, M.
IPC分类号： G06F
CPC分类号： G06Q30/06 , G06Q20/12 , G07B17/00024 , G07B2017/00064
摘要： A system integrates mailing label and/or postage purchasing systems with information that is available locally at a user's workstation or local network and also information that is available globally through a postal service server. The system obtains mailing addresses locally from the user or user's network and/or globally from a postal service server. The system may thus provide an address from the user's workstation and then a more current or appropriate mailing address, based on information available through the postal service. Further, the system maintains the postage and mailing label information supplied by the user in a session that either concludes when the user prints postage stamps and mailing labels locally or continues to allow the user to print or otherwise obtain the postage and mailing labels at a Post Office that communicates with the postal service server. The system also makes available to the user other services that the system funds through a user's postage account. The system may provide services, suchas, money transfers, crediting telephone cards, and so forth, and debit the user's postal account accordingly. The system may also send status messages to the user, an intended recipient or both evidencing the transfer or delivery of funds, mail pieces, and so forth. Further, the system may be combined with a personal mail piece tracking and tracing system, to provide the user with other services that are based, in whole or in part, on information maintained by or under the control of the postal sercice.
摘要翻译：系统将邮件标签和/或邮资采购系统与用户工作站或本地网络本地可用的信息以及通过邮政服务器全局可用的信息进行整合。系统从用户或用户的网络和/或从邮政服务器全局获取本地的邮寄地址。因此，系统可以基于通过邮政服务可用的信息来提供来自用户工作站的地址，然后提供更新的或适当的邮寄地址。此外，系统维护在用户在用户在本地打印邮票和邮寄标签的会话结束时的用户提供的邮资和邮寄标签信息，或者继续允许用户打印或以其他方式获得邮政邮寄标签与邮政服务器通信的办公室。系统还向用户提供系统通过用户的邮资帐户资金的其他服务。该系统可以提供诸如汇款，贷记电话卡等服务，并相应地借记用户的邮政帐户。该系统还可以发送状态消息给用户，预期接收者或两者都证明资金的转移或递送，邮件等等。此外，系统可以与个人邮件跟踪跟踪系统组合，以向用户提供其他服务，其全部或部分地基于由邮政系统维护或由其控制的信息。

90. 发明申请

WO0245017A3 METHOD FOR IMAGE COMPRESSION WITH OPTIMIZATION PARAMETERS 审中-公开
标题翻译：具有优化参数的图像压缩方法
公开(公告)号：WO0245017A3
公开(公告)日：2002-10-10
申请号：PCT/US0146739
申请日：2001-12-03
申请人： LIZARDTECH INC , MURPHY MICHAEL D , DOUGHERTY RANDALL L , BRADLEY JONATHAN N , FABER VANCE
发明人： MURPHY MICHAEL D , DOUGHERTY RANDALL L , BRADLEY JONATHAN N , FABER VANCE
IPC分类号： G06T7/00 , G06T9/00 , G06K9/46 , G06F15/16 , G06K9/36 , H03M3/00 , H03M7/30 , H03M7/32 , H03M7/40 , H04B1/10
CPC分类号： G06T9/00 , G06T7/0002
摘要： In image compression, certain less significant data may be discarded. When multiple sets of image data are involved, an issue may arise as to which sets of data contain the most significant data. The invention is directed to finding efficient computational solutions for the corresponding rate-distortion problem. In a case where there are end blocks which comprise an image, for each block a separate bit stream may be generated with a property that it can be truncated to a variety of discrete lengths. Associated with each length is a measure of distortion that the image would incur if the given block was truncated to a given length. Given a user-specified size for the image, it is desired to find a set of truncation lengths for each block such that the overall distortion to the image is minimized. Alternatively, a user may select a desired quality for the image. The solution provided by the invention is a heuristic based on priority cues to approximate the optimal truncation point so as to meet the desired criteria.
摘要翻译：在图像压缩中，某些较不重要的数据可能被丢弃。当涉及多组图像数据时，可能会出现关于哪组数据包含最重要数据的问题。本发明旨在为相应的速率 - 失真问题找到有效的计算解决方案。在存在包括图像的端块的情况下，对于每个块，可以生成具有可以截断为各种不连续长度的属性的单独位流。与每个长度相关联的是如果给定块被截断到给定长度，图像将产生失真的度量。给定图像的用户指定尺寸，期望为每个块找到一组截断长度，使得对图像的整体失真最小化。或者，用户可以为图像选择期望的质量。本发明提供的解决方案是基于优先级提示的启发式来近似最佳截断点以满足期望的标准。

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