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71. 发明申请

WO2016146590A1 A METHOD FOR DETERMINING AN OPHTHALMIC LENS HAVING UNWANTED ASTIGMATISM 审中-公开
标题翻译：一种用于确定具有不必要的分析方法的眼科镜片的方法
公开(公告)号：WO2016146590A1
公开(公告)日：2016-09-22
申请号：PCT/EP2016/055463
申请日：2016-03-14
申请人： ESSILOR INTERNATIONAL (COMPAGNIE GÉNÉRALE D'OPTIQUE)
发明人： MARCOS, Susana , DORRONSORO, Carlos , VELASCO, Mirian , HERNANDEZ, Martha , CALIXTE, Laurent , MARIN, Gildas
IPC分类号： G02C7/02 , G02C7/06
CPC分类号： A61B3/1035 , A61F2/1624 , G02C7/027 , G02C7/028 , G02C7/04 , G02C7/061 , G02C7/063
摘要： A method for determining an ophthalmic lens having unwanted astigmatism A method for determining an ophthalmic lens having unwanted astigmatism, the ophthalmic lens being adapted to a wearer, wherein the method comprises : -a wearer prescription data providing step during which wearer prescription data indicative of the ophthalmic prescription of the wearer are provided, -a wearer focal data providing step during which wearer focal data indicative of the wearer preferred image focal plan are provided, -a ophthalmic lens determining step during which the ophthalmic lens is determined based on the prescription of the wearer and the wearer focal data so as to reduce the impact of the unwanted astigmatism of the ophthalmic lens for the wearer.
摘要翻译：一种用于确定具有不想要的散光的眼科镜片的方法用于确定具有不想要的散光的眼科镜片的方法，所述眼镜片适合于佩戴者，其中所述方法包括： - 佩戴者处方数据提供步骤，在该佩戴者处方数据提供步骤期间，提供佩戴者的眼科处方， - 提供佩戴者焦点数据提供步骤，在该佩戴者焦点数据提供步骤期间，提供指示佩戴者优选图像焦点平面图的佩戴者焦点数据， - 眼镜透镜确定步骤，其中根据佩戴者和佩戴者的焦点数据，以便减少眼用透镜对佩戴者的不需要的散光的影响。

72. 发明申请

WO2016101025A1 COMPOSITIONS AND METHODS FOR INJECTABLE COMPOSITION FOR AN ACCOMMODATING INTRAOCULAR LENS 审中-公开
标题翻译：用于入院镜片的注射组合物的组合物和方法
公开(公告)号：WO2016101025A1
公开(公告)日：2016-06-30
申请号：PCT/AU2015/050821
申请日：2015-12-21
申请人： BRIEN HOLDEN VISION INSTITUTE
发明人： WATLING, Jason , CLARKE, Stephen , NGUYEN, Kim-Anh Thi , AITCHISON, Tony , MARKOVIC, Elda , BLENCOWE, Anton , LO, Chun Kit
IPC分类号： A61F2/16 , A61K31/695 , C08G77/04 , C08G77/38 , C08G77/42 , C08L83/04 , C08L83/06 , C08L83/10
CPC分类号： C08L83/06 , A61F2/1624 , A61F2240/001 , A61K31/695 , C08G77/14 , C08G77/16 , C08L83/04 , G02B1/04 , C08K5/5419
摘要： The present disclosure relates to injectable compositions and methods of making injectable compositions of moisture curing siloxane polymers for forming accommodating intraocular lenses. In certain embodiments, the moisture curing siloxane polymers are comprised of an organosilicon compound and a hydrolytically sensitive siloxane moiety and have a specific gravity of greater than about 0.95, a number average molecular weight (M n ) greater than about 5,000 or about 20,000 and a weight average molecular weight (M w ) greater than about 20,000 or about 40,000. The disclosure includes accommodating intraocular lenses formed from moisture curing siloxane polymers and having a modulus of elasticity of less than about 6kPa, less than 20% post-cure extractables, refractive index ranging from 1.4 to 1.5 and dioptric range of accommodation of 0D to 10D.
摘要翻译：本公开涉及可注射组合物和制备用于形成容纳眼内透镜的湿固化硅氧烷聚合物的可注射组合物的方法。在某些实施方案中，湿固化硅氧烷聚合物由有机硅化合物和水解敏感性硅氧烷部分组成，并且比重大于约0.95，数均分子量（Mn）大于约5,000或约20,000，重量平均分子量（Mw）大于约20,000或约40,000。本公开包括容纳由湿固化硅氧烷聚合物形成的眼内透镜，并且具有小于约6kPa的弹性模量，小于20％的后固化可提取物，折射率范围为1.4至1.5和屈光度范围为0D至10D。

73. 发明申请

WO2016071717A1 ACCOMMODATING INTRAOCULAR LENS SYSTEMS AND INTRAOCUOLAR LENS FOCUSERS 审中-公开
标题翻译：住院镜片系统和内镜镜片
公开(公告)号：WO2016071717A1
公开(公告)日：2016-05-12
申请号：PCT/GB2015/053384
申请日：2015-11-09
申请人： PAINE, Timothy
发明人： PAINE, Timothy
IPC分类号： A61F2/16
CPC分类号： A61F2/1616 , A61F2/1624 , A61F2/1629 , A61F2002/1681 , A61F2002/1682 , A61F2220/0008 , A61F2220/0025 , A61F2230/0006
摘要： An intraocular lens focuser (114) to be implanted in a human eye includes a resiliently deformable force applicator (140) to apply a focussing force to an accommodating intraocular lens and an attaching portion configured to enable attachment of the lens focuser in the eye. The force applicator is configured such that, in use, when a ciliary muscle of the eye is relaxed to place the accommodating intraocular lens in a distance vision condition, the force applicator is in a deformed condition and when the ciliary muscle contracts to place the accommodating intraocular lens in a near vision condition the force applicator resiles towards a relaxed non-deformed condition to at least assist in placing the accommodating intraocular lens in the near vision condition. The attaching portion has a plurality of members configured to permit attachment of the force applicator to at least one of i) an exterior of a capsular sac of the eye ii) zonules of the eye and iii) the ciliary muscle with the force applicator disposed exteriorly of the capsular sac.
摘要翻译：要植入人眼的眼内透镜聚焦器（114）包括可弹性变形的施力器（140），以将聚焦力施加到容纳的眼内透镜和被配置为能够使眼睛中的透镜聚焦器附接的附接部分。力施加器构造成使得在使用中，当松弛眼睛的睫状肌以将容纳的眼内透镜放置在距离视觉状态时，施力器处于变形状态，并且当睫状肌收缩以将容纳物在近视眼状态下的眼内透镜，力施加器朝向松弛的非变形状态恢复至少有助于将容纳的眼内透镜放置在近视觉状态。附接部分具有多个构件，其构造成允许将施力器附接到i）眼睛的囊囊的外部，ii）眼睛的附属区域中的至少一个，以及iii）具有施加在外部的施力器的睫状肌的囊囊。

74. 发明申请

WO2016061233A1 METHODS AND INTRAOCULAR LENS FOR COUNTERACTING ASTIGMATISM ABERRATIONS 审中-公开
标题翻译：用于排除异常的方法和内窥镜
公开(公告)号：WO2016061233A1
公开(公告)日：2016-04-21
申请号：PCT/US2015/055540
申请日：2015-10-14
申请人： 1CO, INC.
发明人： DEBOER, Charles , TAI, Yu-Chong , HUMAYUN, Mark, S. , SHI, Wendian
IPC分类号： A61F2/16
CPC分类号： A61F2/1645 , A61F2/1624 , A61F2230/0071
摘要： In various embodiments, toric elements shape at least a portion of an outer shell of an implantable intraocular lens to counteract astigmatism aberrations.
摘要翻译：在各种实施例中，复曲面元件形成可植入人工晶状体的外壳的至少一部分以抵消散光像差。

75. 发明申请

WO2015136997A1 眼用レンズ及び眼用レンズの設計方法审中-公开
标题翻译： OPHTHALMIC镜片和设计眼镜镜片的方法
公开(公告)号：WO2015136997A1
公开(公告)日：2015-09-17
申请号：PCT/JP2015/052409
申请日：2015-01-28
申请人：興和株式会社
发明人：石川　治雄
IPC分类号： G02C7/02 , A61F2/16 , G02B7/06 , G02C7/04
CPC分类号： G02C7/028 , A61F2/1624 , A61F2/1637 , A61F2/1643 , A61F2/1645 , A61F2230/0006 , G02B3/06 , G02C7/02 , G02C7/022 , G02C7/04 , G02C2202/22
摘要：レンズ面全体に亘ってトーリック面及び球面・非球面等を規定することができる眼用レンズ及び眼用レンズの設計方法を実現する。眼用レンズを、眼用レンズのレンズ面上の任意の経線方向における断面形状が［数１］を含む式で表現され、ｃは眼用レンズにおける近軸曲率であり、ｒは眼用レンズのレンズ中心からの距離であり、ｋは眼用レンズにおけるレンズ光軸に回転対称な面のコーニック定数であり、ｃ、ｒ、ｋはレンズ面上の経線方向について共通であり、Ａ（θ）及びＢ（θ）は、経線方向の角度に依存する関数で表現されるパラメータである眼内レンズとする。
摘要翻译：提供了一种眼用透镜和用于眼用透镜的设计方法，其中可以在透镜的整个表面上规定复曲面，球面/非球面等。眼科镜片被配置为使得透镜表面上任何子午线方向上的眼镜片的横截面形状由以下等式表示，其包括（1）其中c是眼镜片中的近轴曲率，r是距离透镜中心在眼镜片中，k是在眼镜片中围绕透镜光轴旋转对称的表面的圆锥常数，c，r和k对于透镜表面上的子午线方向是常见的，A（θ）和 B（θ）是根据子午线方向角度函数表示的参数。

76. 发明申请

WO2014141089A3 FOVEATED RETINAL PROSTHESIS 审中-公开
标题翻译：虚构的假期
公开(公告)号：WO2014141089A3
公开(公告)日：2015-02-19
申请号：PCT/IB2014059672
申请日：2014-03-12
申请人： NANO RETINA INC , GEFEN RA ANAN
发明人： GEFEN RA ANAN
IPC分类号： A61N1/36 , A61N1/05
CPC分类号： A61F2/1624 , A61N1/0543 , A61N1/36046
摘要： An apparatus is provided having an intraocular device (20) for implantation entirely in a subject's eye, the intraocular device (20) including: a photosensor array (22) having a plurality of photosensors (24), each photosensor (24) detecting ambient photons and generating a signal in response thereto. A spatial density of the photosensors (24) in a central portion (26) of the array (22) is greater than a spatial density of the photosensors (24) in an outer portion (28) of the array (22). The intraocular device (20) additionally includes a plurality of stimulating electrodes (30) and driving circuitry (32) coupled to the photosensors (24), and configured to drive the electrodes (30) to apply electrical pulses to a retina of the eye in response to the signals from the photosensors (24). Other applications are also described.
摘要翻译：提供一种装置，其具有用于完全植入受试者眼睛的眼内装置（20），所述眼内装置（20）包括：具有多个光电传感器（24）的光电传感器阵列（22），每个光电传感器（24）检测环境光子并响应于此产生信号。阵列（22）的中心部分（26）中的光电传感器（24）的空间密度大于阵列（22）的外部部分（28）中的光电传感器（24）的空间密度。眼内装置（20）还包括耦合到光电传感器（24）的多个刺激电极（30）和驱动电路（32），并被配置为驱动电极（30）将电脉冲施加到眼睛的视网膜响应于来自光电传感器的信号（24）。还描述了其它应用。

77. 发明申请

WO2014176695A1 REPROGRAMMABLE TUNEABLE LIQUID CRYSTAL LENS INTRAOCULAR IMPLANT AND METHODS THEREFOR 审中-公开
标题翻译：可调谐液晶水晶镜片植入物及其方法
公开(公告)号：WO2014176695A1
公开(公告)日：2014-11-06
申请号：PCT/CA2014/050409
申请日：2014-04-30
申请人： LENSVECTOR INC. , GALSTIAN, Tigran
发明人： GALSTIAN, Tigran , EARHART, Howard
IPC分类号： A61F2/16 , A61B3/10 , A61F2/48 , G02F1/133 , H02J17/00
CPC分类号： A61F2/1624 , A61B3/103 , A61F2/1635 , A61F2250/0001 , A61F2250/0002 , A61N1/36046
摘要： A reprogrammable intraocular adaptive lens prosthesis apparatus is provided. The apparatus includes a tunable liquid crystal lens (TLCL) encapsulated in the intraocular prosthesis with control electronics and a power source or in the intraocular prosthesis with a control signal receiver while an external control electronics package transmits the control signal. The TLCL is driven in response to a stimulus signal to provide accommodation. The TLCL corrects other visual shortcomings of the natural eye. The intraocular prosthesis has a remote programmable TLCL controller configured to recalibrate the TLCL to compensate for dynamic adaptation of the eye over time.
摘要翻译：提供了可再编程的眼内适应镜片假体装置。该装置包括在外部控制电子装置封装传送控制信号的情况下，封装在具有控制电子装置的眼内假体的可调谐液晶透镜（TLCL）以及具有控制信号接收器的电源或眼内假体中。响应于刺激信号驱动TLCL以提供住宿。 TLCL校正了自然眼睛的其他视觉缺陷。眼内假体具有远程可编程TLCL控制器，其被配置为重新校准TLCL以补偿眼睛随时间的动态适应。

78. 发明申请

WO2014099345A1 PRESBYOPIA-CORRECTING IOL USING CURVATURE CHANGE OF AN AIR CHAMBER 审中-公开
标题翻译：使用空气室曲率变化的PRESBYOPIA-CORRECTING IOL
公开(公告)号：WO2014099345A1
公开(公告)日：2014-06-26
申请号：PCT/US2013/072746
申请日：2013-12-03
申请人： NOVARTIS AG , CARSON, Daniel R. , LEE, Shinwook
发明人： CARSON, Daniel R. , LEE, Shinwook
IPC分类号： A61F2/16
CPC分类号： B29D11/023 , A61F2/1624 , A61F2/1635 , A61F2/1648
摘要： An accommodative intraocular lens (IOL) system is disclosed for insertion into an eye to provide accommodative vision, the system including a deformable air chamber filled with a transparent, low refractive index medium disposed between the first and second optics; and at least one haptic connected to the air chamber and configured to facilitate a change in the curvature of at least one surface of the chamber, such that when the lens system is positioned in an eye, cilliary muscle movements can alter the curvature of the air chamber and vary the overall lens power of the system.
摘要翻译：公开了一种用于插入眼睛以提供调节视力的调节性眼内透镜（IOL）系统，该系统包括填充有设置在第一和第二光学器件之间的透明低折射率介质的可变形空气室; 以及至少一个触觉件，其连接到所述空气室并且被配置为促进所述腔室的至少一个表面的曲率的改变，使得当所述透镜系统定位在眼睛中时，所述肌肉运动可以改变所述空气的曲率并改变系统的整体透镜功率。

79. 发明申请

WO2014028707A1 BUTTRESSED HAPTIC 审中-公开
公开(公告)号：WO2014028707A1
公开(公告)日：2014-02-20
申请号：PCT/US2013/055093
申请日：2013-08-15
申请人： THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA
发明人： MACCAFFERTY, Sean J.
IPC分类号： A61F2/16 , A61F9/007
CPC分类号： A61F2/16 , A61F2/1624 , A61F2/1635 , A61F2002/1681 , A61F2002/1682 , A61F2002/1689 , A61F2002/169 , A61F2210/0014
摘要： A haptic supporting an intraocular lens (IOL) in the eye permits radial tension from ciliary muscle relaxation rather than contraction to alter the lens power. The IOL is supported by the overlying tissue in the eye such as iris root, sclera and ciliary process, so that anterior and posterior forces on IOL are balanced, and buckling or displacement of lens in the eye or haptic is reduced or prevented. The haptic is of a thickness so as to increase stiffness and to reduce or prevent IOL buckling or displacement.
摘要翻译：在眼睛中支持眼内透镜（IOL）的触觉允许来自睫状肌松弛而不是收缩的径向张力来改变透镜功率。 IOL由眼睛上覆盖的组织支撑，例如虹膜根，巩膜和睫状体，使得IOL上的前后力平衡，减少或防止眼睛或触觉中的晶状体的屈曲或位移。触觉具有厚度以增加刚度并减少或防止IOL屈曲或移位。

80. 发明申请

WO2012004744A2 POLYMERIC COMPOSITION FOR OCULAR DEVICES 审中-公开
标题翻译：用于OCULAR器件的聚合物组合物
公开(公告)号：WO2012004744A2
公开(公告)日：2012-01-12
申请号：PCT/IB2011/052976
申请日：2011-07-05
申请人： POLYMER TECHNOLOGIES INTERNATIONAL (EOU) , ARGAL, Sanjay Ram Swaroop , HUSSAIN, Munavvar Tahir , MALSHE, Vinod Chintamani , PATIL, Abhijit Bhagvat
发明人： ARGAL, Sanjay Ram Swaroop , HUSSAIN, Munavvar Tahir , MALSHE, Vinod Chintamani , PATIL, Abhijit Bhagvat
IPC分类号： C08F220/30 , C08L33/14 , C08K5/00 , G02B1/04 , A61L27/16 , A61F2/16 , G02C7/06
CPC分类号： A61F2/16 , A61F2/1613 , A61F2/1618 , A61F2/1624 , A61F2002/16965 , A61F2230/0006 , A61L27/16 , A61L27/26 , A61L2430/16 , C08F220/18 , C08F220/30 , C08F222/1006 , C08F2220/281 , C08F2220/301 , C08K5/005 , C08K5/13 , C08L33/14 , G02B1/043 , G02C7/022 , G02C7/041 , G02C7/049 , G02C7/06 , G02C2202/20 , C08L33/08
摘要： Polymeric and co-polymeric compositions useful for preparing ophthalmic and ocular devices, such as implantable intraocular lenses (IOL) and contact lenses, and processes of forming the compositions and devices are provided. The disclosed polymeric or co-polymeric composition may include a curcuminoid compound as a UV- blocker, and is derived from a pre-polymerization mixture of monomers which comprises at least 50 weight percents acrylate monomers and exhibiting visible light transparency and ultraviolet light opacity. The disclosed co-polymeric composition may alternatively, or in addition, be derived from a pre-polymerization mixture of monomers including 50 % to 60 % of a first aromatic acrylate monomer, characterized as forming a homopolymer having a refractive index that ranges from 1.50 to 1.53; 15 % to 20 % of a second aromatic acrylate monomer, characterized as forming a homopolymer having a Tg lower by a range of 2 ºC to 30 ºC than the Tg of said first homopolymer; 10 % to 1 % of a third monomer, characterized as forming a homopolymer having a Tg lower than 35 ºC; 5 % to 10 % of a fourth monomer, characterized as forming a homopolymer which is capable of absorbing at least 20 % of water by weight; and 2 % to 5 % of a crosslinking monomer.
摘要翻译：提供了可用于制备眼科和眼睛装置的聚合物和共聚物组合物，例如可植入人工晶状体（IOL）和隐形眼镜，以及形成组合物和装置的方法。所公开的聚合物或共聚物组合物可以包括作为UV阻断剂的姜黄素化合物，并且衍生自包含至少50重量％丙烯酸酯单体并且具有可见光透明度和紫外线不透明度的单体的预聚合混合物。所公开的共聚物组合物可以另外或另外由来自包含50％至60％的第一芳族丙烯酸酯单体的单体的预聚合混合物衍生，其特征在于形成折射率范围为1.50至 1.53; 15％至20％的第二芳族丙烯酸酯单体，其特征在于形成Tg低于所述第一均聚物的Tg的2℃至30℃的Tg的均聚物; 10％至1％的第三单体，其特征在于形成Tg低于35℃的均聚物; 5％至10％的第四单体，其特征在于形成能够吸收至少20重量％的水的均聚物; 和2〜5％的交联单体。

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