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71. 发明申请

WO1996011707A1 RENIBACTERIUM SALMONINARUM VACCINE AND METHOD FOR ITS PREPARATION 审中-公开
标题翻译：盐酸沙门氏菌和其制备方法
公开(公告)号：WO1996011707A1
公开(公告)日：1996-04-25
申请号：PCT/US1995013131
申请日：1995-10-12
申请人： THE STATE OF OREGON acting by and through THE STATE BOARD OF HIGHER EDUCATION on behalf of OREGON STATE UNIVERSITY
发明人： THE STATE OF OREGON acting by and through THE STATE BOARD OF HIGHER EDUCATION on behalf of OREGON STATE UNIVERSITY , CHRISTENSEN, John, M. , KAATTARI, Steve , PIGANELLI, Jon, D. , WIENS, Gregory , ZHANG, Jia, A.
IPC分类号： A61K39/02
CPC分类号： A61K9/5078 , A23K50/80 , A61K39/05 , A61K2039/542 , A61K2039/552 , A61K2039/55555 , A61K2039/55583 , Y10S424/827
摘要： A vaccine and method for treating fish susceptible infection by Renibacterium salmoninarum is described. The vaccine comprises killed microorganisms that lack intact cell-surface-associated protein p57. The vaccine can be used in combination with additional materials, such as, without limitation, adjuvants, plasticizers, pharmaceutical excipients, antigens other than the cells lacking intact cell-surface-associated protein p57, diluents, carriers, binders, lubricants, glidants, aesthetic compounds, such as flavoring and colouring agents, and combinations thereof. The vaccine may be enteric-coated for oral delivery. The enteric coating generally comprises a polymer coating that is impervious to dissolution and/or degradatation in the stomach, but is dissolved upon passing to the higher pH environments of the intestine. A preferred embodiment of the vaccine is made using spherical sugar microspheres. The microsphere is coated with a first layer comprising the killed Renibacterium salmoninarum microorganisms lacking intact cell-surface-associated protein p57. The sugar microsphere is then coated with a second enteric-coating layer comprising a material that is impervious to dissolution and/or degradataion in the stomach of the fish.
摘要翻译：描述了一种用于通过鲑鱼杆菌处理鱼类感染感染的疫苗和方法。该疫苗包含缺乏完整的细胞表面相关蛋白p57的杀死的微生物。疫苗可以与其他材料组合使用，例如但不限于佐剂，增塑剂，药物赋形剂，除了缺乏完整细胞表面相关蛋白p57的细胞以外的抗原，稀释剂，载体，粘合剂，润滑剂，助流剂，美学化合物，例如调味剂和着色剂，及其组合。该疫苗可以肠溶包衣用于口服递送。肠溶包衣通常包含不能在胃中溶解和/或降解的聚合物涂层，但在通过肠的较高pH环境时溶解。疫苗的优选实施方案是使用球形糖微球制备的。微球涂覆有第一层，其包含缺乏完整的细胞表面相关蛋白p57的杀死的沙门氏菌雷贝氏菌微生物。然后将糖微球涂覆有第二肠溶衣层，该第二肠溶衣层包含不能在鱼的胃中溶解和/或降解的材料。

72. 发明申请

WO1994002159A1 DETOXIFICATION OF CERTAIN ENVIRONMENTAL PROTECTION AGENCY DECLARED TOXINS BY NATURALLY OCCURRING ANAEROBIC ORGANISMS 审中-公开
标题翻译：某些环境保护机构通过自然生成的无机有机物对脱毒毒素进行脱氧
公开(公告)号：WO1994002159A1
公开(公告)日：1994-02-03
申请号：PCT/US1993006808
申请日：1993-07-21
申请人： THE STATE OF OREGON ACTING BY AND THROUGH THE ...
发明人： THE STATE OF OREGON ACTING BY AND THROUGH THE ... , CRAIG, Morrie, A.
IPC分类号： A61K35/74
CPC分类号： A62D3/02 , A23K10/18 , A23K30/18 , A23L5/28 , A61K35/741 , A61K35/742 , A61K35/744 , A61K35/747 , A62D2101/20 , A62D2101/22 , A62D2101/28 , B09C1/10
摘要： A method of detoxifying certain Environmental Protection Agency (E.P.A.) priority declared pollutants by exposing the pollutants to a small but detoxifying effective amount of certain naturally occurring bacteria, normally present in sheep's rumen fluid.
摘要翻译：通过将污染物暴露于通常存在于羊的瘤胃液中的某些天然存在的细菌的有效量的一小部分而使某些环境保护局（E.P.A.）优先申报污染物的方法。

73. 发明申请

WO1993017127A1 BOOMERAND DNA AMPLIFICATION 审中-公开
标题翻译： BOOMERAND DNA扩增
公开(公告)号：WO1993017127A1
公开(公告)日：1993-09-02
申请号：PCT/US1993001578
申请日：1993-02-19
申请人： THE STATE OF OREGON acting by and through THE ...
发明人： THE STATE OF OREGON acting by and through THE ... , AHERN, Kevin, G.
IPC分类号： C12Q01/68
CPC分类号： C12N15/10 , C07K14/415 , C12Q1/6853 , C12Q2525/307 , C12Q2525/301 , C12Q2521/501
摘要： Methods for amplifying DNA sequences of interest are disclosed. The methods can be performed using only one primer and are also useful in cloning protocols and for sequencing large DNAs. The methods comprise cleaving a sample DNA using an agent, such as a restriction endonuclease, that produces discrete DNA fragments; ligating the fragments to ''adapter'' polynucleotides having a ligatable end and first and second self-complementary sequences separated by a spacer sequence, thereby forming ligated duplexes; denaturing the ligated duplexes to form templates; annealing molecules of an oligonucleotide primer to the templates, the primers being homologous to a primer target site associated with the sequence of interest; extending the primers using a DNA polymerizing agent to form duplex products; and denaturing the duplex products. Subsequent multiple cycles of annealing primers, extending the primers, and denaturing duplex products are usually performed so as to achieve the desired degree of amplification. Sequencing of large DNAs is performed using multiple rounds of DNA amplification, each round employing a primer homologous with a primer target site in the sequence of interest previously amplified. Cloning is facilitated by including a replication origin and selectable marker in the adapters.
摘要翻译：公开了扩增感兴趣的DNA序列的方法。该方法只能使用一个引物进行，也可用于克隆方案和测序大型DNA。所述方法包括使用产生离散DNA片段的试剂例如限制性内切核酸酶切割样品DNA; 将片段连接到具有可连接末端的“衔接子”多核苷酸和由间隔序列分隔的第一和第二自身互补序列，从而形成连接的双链体; 使连接的双链体变性以形成模板; 将寡核苷酸引物的退火分子与模板反应，引物与与感兴趣的序列相关的引物靶位点同源; 使用DNA聚合剂扩展引物以形成双链体产物; 并使双相产物变性。通常进行随后的退火引物，延伸引物和变性双链体的多个循环，以达到所需的扩增程度。使用多轮DNA扩增进行大DNA的测序，每轮使用与预先扩增的感兴趣序列中的引物靶位点同源的引物。通过在适配器中包含复制起点和可选标记来促进克隆。

74. 发明申请

WO1990015606A1 CNQX AND ITS ANALOGS AS THERAPEUTICS FOR DEGENERATIVE NEURAL DISEASES 审中-公开
标题翻译： CNQX及其类似物作为退化性神经疾病的治疗方法
公开(公告)号：WO1990015606A1
公开(公告)日：1990-12-27
申请号：PCT/US1990003337
申请日：1990-06-13
申请人： THE STATE OF OREGON, acting by and through THE ...
发明人： THE STATE OF OREGON, acting by and through THE ... , JAHR, Craig, E. , LESTER, Robin , WEBER, Eckard
IPC分类号： A61K31/495
CPC分类号： A61K31/495
摘要： Compounds of formula (I), wherein each X is independently nitro or cyano and wherein each Y is independently H, lower alkyl (1-4C), lower alkoxy (1-4C), or CF3 have been shown to be successful antagonists of NMDA receptors. Accordingly, these compounds are useful in the treatment of neuronal conditions associated with stimulation of the NMDA receptor.

75. 发明申请

WO2017222551A1 AMORPHOUS THIN METAL FILM 审中-公开
标题翻译：非晶态金属薄膜
公开(公告)号：WO2017222551A1
公开(公告)日：2017-12-28
申请号：PCT/US2016/039204
申请日：2016-06-24
申请人： HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. , THE STATE OF OREGON
发明人： ABBOTT JR., James Elmer , MCGLONE, John M. , OLSEN, Kristopher , PUGLIESE, Roberto A. , LONG, Greg Scott , KESZLER, Douglas , WAGER, John
IPC分类号： C23C30/00 , C22C45/00 , C23C4/04 , C23C14/06 , B41J2/335
摘要： An amorphous thin metal film can include a combination of metals or metalloids including: 5 at% to 74 at% of a metalloid selected from the group of carbon, silicon, and boron; 5 at% to 74 at% of a first metal; 5 at% to 74 at% of a second metal; and 5 at% to 70 at% of a dopant. The first and second metals can be independently selected from the group of titanium, vanadium, chromium, iron, cobalt, nickel, zirconium, niobium, molybdenum, ruthenium, rhodium, palladium, hafnium, tantalum, tungsten, osmium, iridium, or platinum, wherein the first metal and the second metal can be different metals. The dopant can be selected from the group of oxygen, nitrogen, or combinations thereof. The metalloid, first metal, second metal, and dopant can account for at least 70 at% of the amorphous thin metal film.
摘要翻译：非晶金属薄膜可以包括金属或类金属的组合，包括：5at％至74at％的选自碳，硅和硼的准金属; 5at％至74at％的第一金属; 5at％至74at％的第二金属; 和5原子％至70原子％的掺杂剂。第一和第二金属可以独立地选自钛，钒，铬，铁，钴，镍，锆，铌，钼，钌，铑，钯，铪，钽，钨，锇，铱或铂的组，其中第一金属和第二金属可以是不同的金属。掺杂剂可以选自氧气，氮气或其组合。所述准金属，第一金属，第二金属和掺杂剂可以占所述非晶金属薄膜的至少70原子％。

76. 发明申请

WO2015116066A1 OXYGEN CONDUCTING BISMUTH PEROVSKITE MATERIAL 审中-公开
标题翻译：氧气导电双相烧结材料
公开(公告)号：WO2015116066A1
公开(公告)日：2015-08-06
申请号：PCT/US2014/013611
申请日：2014-01-29
申请人： HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. , THE STATE OF OREGON acting by and through THE STATE BOARD OF HIGHER EDUCATION on behalf of OREGON STATE UNIVERSITY
发明人： CANN, David , GIBBONS, Brady , TRIAMNAK, Narit , ABBOTT, James Elmer JR.
IPC分类号： C04B35/453 , C04B35/01
CPC分类号： C04B35/475 , C04B35/462 , C04B35/465 , C04B35/64 , C04B2235/3201 , C04B2235/3206 , C04B2235/3234 , C04B2235/3236 , C04B2235/3279 , C04B2235/3284 , C04B2235/3298 , C04B2235/768 , C04B2235/79 , G01N27/4073 , H01L41/187
摘要： The present disclosure is drawn to an oxygen conducting bismuth perovskite material, a method of conducting oxygen through the material, and a method of making the material. The oxygen conducting bismuth perovskite material can include two components selected from the group consisting of NBT, KBT, BZT, BMT, and BNiT. The material can also have a sufficient degree of non-stoichiometry to provide oxygen vacancies to conduct oxide ions.
摘要翻译：本公开内容涉及导电铋钙钛矿材料，通过材料传导氧的方法以及制造该材料的方法。导电铋钙钛矿材料可以包括选自NBT，KBT，BZT，BMT和BNiT的两种组分。该材料还可以具有足够的非化学计量度以提供氧空位来导电氧化物离子。

77. 发明申请

WO2014074360A1 AMORPHOUS METAL THIN-FILM NON-LINEAR RESISTOR 审中-公开
标题翻译：非晶金属薄膜非线性电阻器
公开(公告)号：WO2014074360A1
公开(公告)日：2014-05-15
申请号：PCT/US2013/067443
申请日：2013-10-30
申请人： THE STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF OREGON STATE UNIVERSITY
发明人： COWELL III, William, E.
IPC分类号： H01C1/012 , H01L21/00
CPC分类号： H01C1/142 , H01C1/14 , H01C7/006 , H01C17/12 , H01L28/20 , H01L28/24
摘要： An amorphous metal thin-film non-linear resistor (AMNR) is provided. The AMNR is an electronic device possessing symmetric non-linear current-voltage (I-V) characteristics, an exemplary configuration of which may comprise three sequentially deposited layers which include a lower amorphous metal thin-film (AMTF) interconnect, a thin-film insulator located on top of the AMTF interconnect, and two upper conductive contacts located on top of the insulator and disposed in the same physical plane.
摘要翻译：提供非晶金属薄膜非线性电阻（AMNR）。 AMNR是具有对称非线性电流 - 电压（IV）特性的电子设备，其示例性配置可以包括三个顺序沉积的层，其包括下部非晶金属薄膜（AMTF）互连，位于在AMTF互连的顶部，以及位于绝缘体顶部并且设置在同一物理平面中的两个上导电触点。

78. 发明申请

WO2012015974A1 ISOTOPE PRODUCTION TARGET 审中-公开
标题翻译：同位素生产目标
公开(公告)号：WO2012015974A1
公开(公告)日：2012-02-02
申请号：PCT/US2011/045613
申请日：2011-07-27
申请人： THE STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF OREGON STATE UNIVERSITY , REESE, Steven Richard , PALMER, Todd Stephen , KELLER, Stephen Todd , MUNK, Madicken
发明人： REESE, Steven Richard , PALMER, Todd Stephen , KELLER, Stephen Todd , MUNK, Madicken
IPC分类号： G21C3/00
CPC分类号： G21G1/02 , G21G1/00 , G21G2001/0036 , G21K5/08
摘要： An isotope production target may include an outer diameter wall and an inner diameter wall. An isotope source may be located between the inner diameter wall and the outer diameter wall, and the isotope source may comprise fissile material interspersed with one or more voided regions. A central region may be located within the inner diameter wall, and the central region may be configured to house a neutron thermalization volume.
摘要翻译：同位素生产目标可以包括外径壁和内径壁。同位素源可以位于内径壁和外径壁之间，同位素源可以包括散布有一个或多个空隙区域的裂变材料。中心区域可以位于内径壁内，并且中心区域可以被配置为容纳中子热化体积。

79. 发明申请

WO2010120364A2 IMPEDIMETRIC SENSORS USING DIELECTRIC NANOPARTICLES 审中-公开
标题翻译：使用介电纳米粒子的绝缘传感器
公开(公告)号：WO2010120364A2
公开(公告)日：2010-10-21
申请号：PCT/US2010/001112
申请日：2010-04-14
申请人： THE STATE OF OREGON acting by and through THE STATE BOARD OF HIGHER EDUCATION on behalf of THE PORTLAND STATE UNIVERSITY , SOLANKI, Rajendra
发明人： SOLANKI, Rajendra
IPC分类号： G01N27/26 , G01N33/50 , C12Q1/68
CPC分类号： G01N33/54346 , C12Q1/6825 , C12Q2563/155
摘要： A method for electrochemical impedance spectroscopy uses interdigitated electrodes functionalized with a first species and nanoparticles functionalized with a second species that preferentially attaches to the first species. The nanoparticles are composed of a material with a dielectric constant (k value) greater than 2. The chemically functionalized electrodes are then exposed to a solution containing the chemically functionalized nanoparticles which then become immobilized on the electrodes through the attachment of the first species to the second species. The impedance spectrum is measured and an amount of the first species is then determined from the measured spectrum. Because the high-k dielectric nanoparticles increase the double-layer capacitive impedance, the sensitivity of determining the amount of the first species attached to the second species is enhanced.
摘要翻译：电化学阻抗光谱法的一种方法是使用由第一物质官能化的交错电极和用优先附着于第一物质的第二物质官能化的纳米颗粒。纳米颗粒由具有大于2的介电常数（k值）的材料组成。然后将化学官能化的电极暴露于含有化学官能化纳米颗粒的溶液中，其然后通过将第一种类附着到电极上而固定在电极上第二种。测量阻抗谱，然后从测量的光谱确定第一种的量。因为高k电介质纳米粒子增加了双层电容阻抗，所以确定连接到第二种的第一物质的量的灵敏度得到增强。

80. 发明申请

WO2009155082A1 A RADIO-FREQUENCY-FREE HYBRID ELECTROSTATIC/MAGNETOSTATIC CELL FOR TRANSPORTING, TRAPPING, AND DISSOCIATING IONS IN MASS SPECTROMETERS 审中-公开
标题翻译：用于在大量光谱仪中运输，捕获和分解离子的无线电频率混合静电/磁性细胞
公开(公告)号：WO2009155082A1
公开(公告)日：2009-12-23
申请号：PCT/US2009/045591
申请日：2009-05-29
申请人： THE STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF OREGON STATE UNIVERSITY , BAROFSKY, Douglas, F. , BECKMAN, Joseph, S. , DEINZER, Max, L. , VOINOV, Valery, G.
发明人： BAROFSKY, Douglas, F. , BECKMAN, Joseph, S. , DEINZER, Max, L. , VOINOV, Valery, G.
IPC分类号： H01J49/28
CPC分类号： H01J49/0054 , H01J49/062
摘要： Mass spectrometry cells include one or more interleaved magnetostatic and electrostatic lenses. In some examples, the electrostatic lenses are based on electrical potentials applied to magnetostatic lens pole pieces. In other alternatives, the electrostatic lenses can include conductive apertures. Applied voltages can be selected to trap or transport charged particles, and photon sources, gas sources, ion sources, and electron sources can be provided for various dissociation processes.
摘要翻译：质谱细胞包括一个或多个交错的静磁和静电透镜。在一些示例中，静电透镜基于施加到静磁透镜极片的电位。在其他替代方案中，静电透镜可以包括导电孔。可以选择施加的电压来捕获或输送带电粒子，并且可以为各种解离过程提供光子源，气体源，离子源和电子源。

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