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    • 65. 发明申请
    • SKIN EMOLLIENTS
    • 皮肤感觉
    • WO1994021223A1
    • 1994-09-29
    • PCT/EP1994000663
    • 1994-03-07
    • UNILEVER PLCUNILEVER NV
    • UNILEVER PLCUNILEVER NVROBLES, Enrique, Cubero
    • A61K07/48
    • A61Q19/00A61K8/37A61Q19/007A61Q19/08
    • A compound suitable for use as a skin emollient comprising the esterification product of an aliphatic alcohol having at least 25 carbon atoms, and an unsaturated aliphatic fatty acid having at least 16 carbon atoms. Preferably the alcohol is unsaturated and has at no more than 35 carbon atoms such as cerotyl and melissyl alcohols and the fatty acid has no more than 24 carbon atoms such as linoleic or oleic acids and has 1 to 6 methylene interrupted double bonds. At a concentration of substantially 1 mg/cm the compound has an occlusivity of at least 50 %, more preferably 65 %, and especially preferably 75 %. A preferred compound according to the invention is cerotyl linoleate. The invention includes compositions containing such compounds, the use of these compounds as skin emollients and a method of cosmetically treating dry, hard or cracked skin.
    • 适合用作皮肤润肤剂的化合物,其包含具有至少25个碳原子的脂族醇的酯化产物和具有至少16个碳原子的不饱和脂族脂肪酸。 优选醇是不饱和的,并且不超过35个碳原子,如甲氧基和蜜胺醇,并且脂肪酸不超过24个碳原子,例如亚油酸或油酸,并且具有1至6个亚甲基中断的双键。 在基本上1mg / cm 2的浓度下,该化合物具有至少50%,更优选65%,特别优选75%的吸留性。 根据本发明的优选化合物是亚油酸亚油酸酯。 本发明包括含有这些化合物的组合物,这些化合物作为皮肤润肤剂的用途以及美容处理干,硬或破裂皮肤的方法。