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61. 发明申请

WO2005003163A1 SUSHI PEPTIDE MULTIMER 审中-公开
标题翻译： SUSPHPDE多媒体
公开(公告)号：WO2005003163A1
公开(公告)日：2005-01-13
申请号：PCT/SG2004/000194
申请日：2004-07-02
申请人： NATIONAL UNIVERSITY OF SINGAPORE , DING, Jeak, Ling , HO, Bow
发明人： DING, Jeak, Ling , HO, Bow
IPC分类号： C07K14/47
CPC分类号： C12Y304/21084 , A61K38/00 , C12N9/6408 , Y10S435/975 , Y10S530/81 , Y10S930/28
摘要： Endotoxin, also known as lipopolysaccharides (LPS), is the major mediator of septic shock due to Gram-negative bacterial infection. Chemically synthesized S3 peptide, derived from Sushi3 domain of Factor C, which is the endotoxin-sensitive serine protease of the limulus coagulation cascade, binds and neutralizes LPS activity. Fluorescent tagged-S3 is shown to detect LPS-containing bacteria. For large-scale production of S3 and to mimick other pathogen-recognizing molecules, tandem multimers of the S3 gene were constructed and expressed in E. coli. Tetramer of S3 for example is shown to display an enhanced inhibitory effect on LPS-induced activities. An affinity matrix based on tetramer of S3 is also shown to be particularly efficient at removing LPS.
摘要翻译：内毒素也被称为脂多糖（LPS），是革兰氏阴性细菌感染引起的败血性休克的主要介质。衍生自因子C的Sushi3结构域的化学合成的S3肽，其是鲎凝血级联的内毒素敏感的丝氨酸蛋白酶，其结合并中和LPS活性。荧光标记的S3显示检测含LPS细菌。为了大规模生产S3并模拟其他病原体识别分子，构建了S3基因的串联多聚体并在大肠杆菌中表达。 S3的四聚体显示出增强的对LPS诱导的活性的抑制作用。基于S3的四聚体的亲和基质也显示出在去除LPS时特别有效。

62. 发明申请

WO2004094667A3 REAGENTS AND METHODS FOR DETECTING SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 审中-公开
公开(公告)号：WO2004094667A3
公开(公告)日：2004-11-04
申请号：PCT/SG2004/000103
申请日：2004-04-21
申请人： GENOME INSTITUTE OF SINGAPORE , REN, Ee Chee , HIBBERD, Martin, L. , NG, Lisa Fong Poh
发明人： REN, Ee Chee , HIBBERD, Martin, L. , NG, Lisa Fong Poh
IPC分类号： C12Q1/70
摘要： This invention provides reagents and methods for detecting the severe acute respiratory syndrome coronavirus (SARS CoV). This invention also provides related compositions, kits, systems, and computers.

63. 发明申请

WO2004087378A1 SWITCHING FLUID FLOW BY DIVERSION 审中-公开
标题翻译：通过DIVERSION切换流体流
公开(公告)号：WO2004087378A1
公开(公告)日：2004-10-14
申请号：PCT/SG2004/000073
申请日：2004-03-30
申请人： JETSIS INTERNATIONAL PTE LTD , GADD, Michael, William
发明人： GADD, Michael, William
IPC分类号： B24C7/00
CPC分类号： B24C7/0023 , B24C1/045 , B24C7/003 , F16K11/0743 , Y10T137/86863
摘要： A flow of fluid is switched on and off by diverting the flow to an alternative path. In a preferred application an abrasive cutting jet, formed by a flow of abrasive slurry fed via a conduit 5 to a cutting jet nozzle 6, is switched on and off by diverting the flow at a three way changeover valve 1 to a conduit 8 and bypass nozzle 9. Valves 18, 20 control the connection to of a flow of clean auxiliary water to respective outlet ports 4, 7 of the changeover valve 1 to reduce pressure differentials during operation of the changeover valve and to provide clean backflows which hydraulically divert the flow of abrasive slurry at the changeover valve and allow the changeover valve to open and close on a clean, largely abrasive-free flow.
摘要翻译：通过将流转向替代路径来打开和关闭流体流。在优选的应用中，由通过导管5供给到切割喷嘴6的研磨浆料流形成的研磨切割射流通过将三通切换阀1上的流转向管道8而被打开和关闭喷嘴9.阀18,20控制与转换阀1的相应出口端口4,7的清洁辅助水流的连接，以减少切换阀操作期间的压力差，并提供清洁的回流，液压转向流动在切换阀处的磨料浆料，并允许切换阀打开和关闭清洁，大部分无磨损的流动。

64. 发明申请

WO2004086564A1 HIGH DENSITY ELECTRICAL CONNECTOR 审中-公开
标题翻译：高密度电气连接器
公开(公告)号：WO2004086564A1
公开(公告)日：2004-10-07
申请号：PCT/SG2004/000070
申请日：2004-03-25
申请人： FCI ASIA TECHNOLOGY PTE LTD , SOH, Lip, Teck
发明人： SOH, Lip, Teck
IPC分类号： H01R4/48
CPC分类号： H01R13/2442 , H01R12/57
摘要： A compression connector (1) for interconnecting a two electrical devices comprising, a housing (2) mounting at least one conductive element (3) defining; a first beam section (7) fastened to the housing (4) in a cantilevered manner allowing resilient deflection and having a first contact region (5) at the fastened end for connection to the first device, and a second beam section (8) extending at a first end thereof in a cantilevered manner from the movable end of the first beam section, the second beam section including a second contact (6) region away from the first end and disposed to engage with compressively, and deflectable by the first device. The conductive element is formed by out of plane bending to position the second beam back over the first beam, so that the wiping action by the first contact region of the second beam in a direction transverse to the compression engagement direction is controlled by geometry selection of the beams.
摘要翻译：一种用于互连两个电气设备的压缩连接器（1），包括：安装至少一个导电元件（3）的壳体（2）第一梁部分（7）以悬臂方式固定到壳体（4），允许弹性偏转并且在紧固端处具有用于连接到第一装置的第一接触区域（5），以及第二梁部分（8）在其第一端部处以悬臂方式从第一梁部分的可移动端延伸，第二梁部分包括远离第一端部的第二接触部分（6），并且被布置成可被第一装置压缩地接合并可偏转。导电元件由平面外弯曲形成，以将第二光束定位在第一光束之上，使得第二光束的第一接触区域在与压缩接合方向相交的方向上的擦拭作用由几何选择梁。

65. 发明申请

WO2004085318A1 APPARATUS AND METHOD FOR CONTINUOUS ELECTRODEIONIZATION 审中-公开
标题翻译：用于连续电极化的装置和方法
公开(公告)号：WO2004085318A1
公开(公告)日：2004-10-07
申请号：PCT/SG2004/000071
申请日：2004-03-25
申请人： CHEMITREAT PTE LTD , DEY, Avijit , THOMAS, Gareth, Hugh
发明人： DEY, Avijit , THOMAS, Gareth, Hugh
IPC分类号： C02F1/44
CPC分类号： B01D61/025 , B01D61/022 , B01D61/04 , B01D61/48 , B01D61/58 , B01D2311/04 , C02F1/20 , C02F1/283 , C02F1/32 , C02F1/441 , C02F1/4695 , C02F1/52 , C02F1/683 , C02F5/00 , C02F5/10 , C02F2001/425 , C02F2101/12 , C02F2101/36 , C02F2103/04 , C02F2209/06 , Y10S210/90 , Y10S210/908 , B01D2311/2603 , B01D2311/268 , B01D2311/2623
摘要： A method of water purification including the steps of passing source water through at least one reverse osmosis unit (6, 8) to produce a product water and reject water, directing the product water from a reverse osmosis unit (6, 8) into the dilution stream of a continuous electrodeionization unit (12), directing the reject water from the first pass reverse osmosis unit (6) through a softening unit (7) to produce softening unit output water with fewer hardness elements than the reject water from the first pass reverse osmosis unit (6), directing the softening unit output water into a concentrate stream of the continuous electrodeionization unit (12), and wherein the continuous electrodeionization unit (12) further purifies the water from the dilution stream to produce purified water.
摘要翻译：一种水净化方法，包括以下步骤：使源水通过至少一个反渗透单元（6,8）以产生产物水并排出水，将产物水从反渗透单元（6,8）引入稀释液连续电去离子单元（12）的流，通过软化单元（7）将来自第一通道反渗透单元（6）的排出水引导以产生比来自第一遍反向的废水更少的硬度元素的软化单元输出水渗透单元（6），将软化单元输出水引导到连续电去离子单元（12）的浓缩物流中，并且其中连续电去离子单元（12）进一步净化来自稀释流的水以产生净化水。

66. 发明申请

WO2004071550A3 WEB STRUCTURE MEMBRANE SPACER 审中-公开
公开(公告)号：WO2004071550A3
公开(公告)日：2004-08-26
申请号：PCT/SG2004/000036
申请日：2004-02-11
申请人： HYFLUX LTD , LUM, Ooi, Lin, Olivia , LING, Lay, Pee , NEO, Yew, Chin , VENKIDACHALAM, Govindharaju , LEE, Kam, Chern , CHEN, Kwok, Ming
发明人： LUM, Ooi, Lin, Olivia , LING, Lay, Pee , NEO, Yew, Chin , VENKIDACHALAM, Govindharaju , LEE, Kam, Chern , CHEN, Kwok, Ming
IPC分类号： B01D61/28
摘要： A membrane spacer comprising two or more sub-spacers (32). The at least one sub-spacer includes an inlet aperture and an outlet aperture (20) where the inlet aperture connected to the outlet aperture by a substantially curved flow path. The substantially curved flow path includes a plurality of grid sectors (23) running perpendicular to the curved flow path. The two or more sub-spacers (32) are aligned to provide a tortuous flow path between the inlet aperture and the outlet aperture (20).

67. 发明申请

WO2004070405A1 PROBE CARD NEEDLE CLEANING FREQUENCY OPTIMIZATION 审中-公开
标题翻译：探针卡针清洁频率优化
公开(公告)号：WO2004070405A1
公开(公告)日：2004-08-19
申请号：PCT/SG2003/000023
申请日：2003-02-05
申请人： SYSTEMS ON SILICON MANUFACTURING CO. PTE. LTD. , TAN BEN GHEE
发明人： TAN BEN GHEE
IPC分类号： G01R31/28
CPC分类号： B08B3/00 , G01R3/00
摘要： A system and method for optimizing cleaning of a probe card including using the probe card to test the functionality of dies on a wafer, when a die fails the probe test, and the probe reports failure to contact the pads of the die, checking the resistance of the probe needles, and if the resistance of a probe needle is greater than a predetermined value triggering probe needle cleaning.
摘要翻译：一种用于优化扫描卡的清洁的系统和方法，包括使用探针卡来测试晶片上的管芯的功能，当管芯未通过探针测试时，探头报告不能接触管芯的焊盘，检查电阻并且如果探针的电阻大于触发探针针清洁的预定值。

68. 发明申请

WO2004027363A1 TEMPERATURE TELEMETER 审中-公开
公开(公告)号：WO2004027363A1
公开(公告)日：2004-04-01
申请号：PCT/SG2003/000225
申请日：2003-09-19
申请人： DSO NATIONAL LABORATORIES , LIM, Chin, Leong
发明人： LIM, Chin, Leong
IPC分类号： G01K13/00
CPC分类号： G01K1/02
摘要： A temperature telemetric sender and a temperature telemeter (50) using one or more of the senders with a single or common receiver (64) are provided. The temperature telemetric sender includes a sensor (52) to measure a temperature of a body cavity, preferably an ear canal, of a subject. A transmitter (60) coupled to the sensor is responsive to the sensor and transmits a signal indicative of the temperature of the body cavity. The receiver (64) receives the signal wirelessly from the transmitter. The temperature values received by the receiver may be compensated for changes in ambient temperature, measured at the sender or receiver, and may be converted into an estimation of a core body temperature. The temperatures may be displayed, preferably as a series of temperatures displayed graphically. An alarm (66) may be provided when the received signal, or a temperature value derived from it, is indicative of a temperature equaling a predetermined temperature or falling outside a predetermined temperature range. Intermediate transceivers, which relay temperature signals from respective senders to the common receiver, may be used to extend the operational range.
摘要翻译：提供了使用具有单个或公共接收器（64）的一个或多个发送器的温度遥测发送器和温度传感器（50）。温度遥测发射器包括用于测量受试者的体腔（优选为耳道）的温度的传感器（52）。耦合到传感器的发射器（60）响应于传感器并传输指示体腔温度的信号。接收机（64）从发射机无线地接收信号。接收器接收的温度值可以补偿在发送器或接收器处测量的环境温度的变化，并且可以被转换为核心体温度的估计。可以显示温度，优选以图形显示的一系列温度。当接收到的信号或从其导出的温度值指示等于预定温度或落在预定温度范围之外的温度时，可以提供报警器（66）。将来自相应发送者的温度信号传送到公共接收器的中间收发器可用于扩展操作范围。

69. 发明申请

WO2004015821A1 AN ELECTRICAL CONNECTOR 审中-公开
标题翻译：电气连接器
公开(公告)号：WO2004015821A1
公开(公告)日：2004-02-19
申请号：PCT/SG2003/000185
申请日：2003-07-31
申请人： FCI ASIA TECHNOLOGY PTE LTD , SOH, Teck
发明人： SOH, Teck
IPC分类号： H01R13/639
CPC分类号： H01R12/7011 , H01R12/7082 , H01R12/714 , H01R13/24
摘要： An electrical connector to interpose between a first electrical device and a second electrical device each having a plurality of conductive pads to electrically, the electrical connector comprising a housing carrying a plurality of conductive elements, each conductive element including a first contact region for engagement with a conductive pad of the first electrical device and a second contact region for engagement with a conductive pad of the second electrical device. The conductive elements are carried by the housing to present at least the first contact region for compressive engagement with the surface of the first electrical device. The housing presents a latching means to engage with the first electrical device to retain the first electrical device with the housing in a direction which extends parallel to the direction of compressive engagement to thereby hold the plurality of conductive pads of the first electrical device in physical contact with respective the first contact regions of the conductive elements.
摘要翻译：一种电连接器，其插入在第一电气设备和第二电气设备之间，每个电气设备具有多个导电焊盘以电连接，所述电连接器包括承载多个导电元件的壳体，每个导电元件包括用于与第一电气设备的导电焊盘和用于与第二电气设备的导电焊盘接合的第二接触区域。导电元件由壳体承载，以至少呈现第一接触区域，用于与第一电气设备的表面压缩接合。壳体具有闩锁装置，以与第一电气装置接合以将第一电气装置与壳体保持在平行于压缩接合方向延伸的方向上，从而将第一电气装置的多个导电垫保持物理接触与导电元件的第一接触区域相对应。

70. 发明申请

WO2003065052A2 METHOD OF MANUFACTURING AN ACCELEROMETER 审中-公开
标题翻译：制造加速度计的方法
公开(公告)号：WO2003065052A2
公开(公告)日：2003-08-07
申请号：PCT/SG2003/000003
申请日：2003-01-07
申请人： SENSFAB PTE LTD , CHONG, Wai, Mun , CHIR, Kim, Pong, Daniel , KOR, Kitt, Wai , KATHIRGAMASUNDARAM, Sooriakumar , BRYAN, Keith, Patmon
发明人： CHONG, Wai, Mun , CHIR, Kim, Pong, Daniel , KOR, Kitt, Wai , KATHIRGAMASUNDARAM, Sooriakumar , BRYAN, Keith, Patmon
IPC分类号： G01P15/00
CPC分类号： B81C1/00269 , B81C2203/0118 , B81C2203/019 , B81C2203/032 , G01P1/023 , G01P15/0802 , G01P15/125 , G01P2015/0814 , H01L2924/0002 , H01L2924/00
摘要： A method for manufacturing an accelerometer that includes the steps of etching at least one cavity into the top side of a substrate, bonding a top layer of material onto the top side of the substrate, depositing metallization onto the layer of material and etching to top layer of material to form a sensor structure suspended over each cavity.
摘要翻译：一种用于制造加速度计的方法，包括以下步骤：将至少一个空腔蚀刻到衬底的顶侧，将顶层材料粘合到衬底的顶侧上，将金属化沉积到材料层上并蚀刻到顶层的材料以形成悬挂在每个空腔上的传感器结构。

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