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51. 发明申请

WO2011007126A2 DISEASE DETERMINATION 审中-公开
标题翻译：疾病决定
公开(公告)号：WO2011007126A2
公开(公告)日：2011-01-20
申请号：PCT/GB2010001330
申请日：2010-07-13
申请人： UNIV MANCHESTER , GRAHAM JAMES , DABBAH MOHAMMAD A , MALIK RAYAZ
发明人： GRAHAM JAMES , DABBAH MOHAMMAD A , MALIK RAYAZ
IPC分类号： G06T7/00
CPC分类号： G06T7/0012 , G06T5/30 , G06T2207/10056 , G06T2207/30041
摘要： A method of generating data providing a quantitative indication of the presence or absence of disease from a corneal image of a patient. The method comprises processing the image to identify at least one linear structure, processing the at least one identified linear structure to generate data indicating properties of the at least one identified linear structure and processing the data indicating properties of the at least one identified linear structure to generate the data providing a quantitative indication of the presence or absence of disease.
摘要翻译：一种产生数据的方法，提供来自患者的角膜图像的疾病的存在或不存在的定量指示。所述方法包括处理所述图像以识别至少一个线性结构，处理所述至少一个所识别的线性结构以产生指示所述至少一个识别的线性结构的属性的数据，以及处理指示所述至少一个所识别的线性结构的属性的数据，产生提供疾病存在或不存在的定量指示的数据。

52. 发明申请

WO2009006567A2 PYRIMIDYL CYCLOPENTANES AS AKT PROTEIN KINASE INHIBITORS 审中-公开
标题翻译：作为AKT蛋白激酶抑制剂的嘧啶基环戊烷
公开(公告)号：WO2009006567A2
公开(公告)日：2009-01-08
申请号：PCT/US2008/069144
申请日：2008-07-03
申请人： ARRAY BIOPHARMA INC. , GENENTECH, INC. , BENCSIK, Josef , BLAKE, James, F. , GRAHAM, James, M. , HENTEMANN, Martin, F. , KALLAN, Nicholas, C. , MITCHELL, Ian, S. , SCHLACTER, Stephen, T. , SPENCER, Keith, L. , XIAO, Dengming , XU, Rui , WELCH, Mike , LIANG, Jun , SAFINA, Brian, S.
发明人： BENCSIK, Josef , BLAKE, James, F. , GRAHAM, James, M. , HENTEMANN, Martin, F. , KALLAN, Nicholas, C. , MITCHELL, Ian, S. , SCHLACTER, Stephen, T. , SPENCER, Keith, L. , XIAO, Dengming , XU, Rui , WELCH, Mike , LIANG, Jun , SAFINA, Brian, S.
IPC分类号： C07D401/12 , C07D403/12
CPC分类号： C07D403/12 , C07D401/12
摘要： The present invention provides compounds of Formula (I), including tautomers, resolved enantiomers, diastereomers, solvates, metabolites, salts and pharmaceutically acceptable prodrugs thereof. Also provided are methods of using the compounds of this invention as AKT protein kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.
摘要翻译：本发明提供式（I）的化合物，包括其互变异构体，拆分的对映异构体，非对映异构体，溶剂化物，代谢物，盐和药学上可接受的前药。还提供了使用本发明化合物作为AKT蛋白激酶抑制剂并用于治疗过度增殖性疾病如癌症的方法。

53. 发明申请

WO2008091439A1 PROCESS FOR CRACKING SYNTHETIC CRUDE OIL-CONTAINING FEEDSTOCK 审中-公开
标题翻译：破碎含油原料的方法
公开(公告)号：WO2008091439A1
公开(公告)日：2008-07-31
申请号：PCT/US2007/085826
申请日：2007-11-29
申请人： EXXONMOBIL CHEMICAL PATENTS INC. , KEUSENKOTHEN, Paul, F. , MCCOY, James, N. , GRAHAM, James, E. , REIMANN, Chad, D.
发明人： KEUSENKOTHEN, Paul, F. , MCCOY, James, N. , GRAHAM, James, E. , REIMANN, Chad, D.
IPC分类号： C10G69/06
CPC分类号： C10G69/06 , Y10S585/921
摘要： A process for steam cracking liquid hydrocarbon feedstocks containing synthetic crude oil comprises i) hydroprocessing a wide boiling range aliquot containing a) normally liquid hydrocarbon portion substantially free of resids and b) thermally cracked hydrocarbon liquid, boiling in a range from 600° to 1050°F, to provide a synthetic crude oil substantially free of resids; ii) adding to the synthetic crude oil a normally liquid hydrocarbon component boiling in a range from 100° to 1050°F; and iii) cracking the mixture resulting from ii) in a cracker furnace comprising a radiant coil outlet to provide a cracked effluent, wherein the cracking is carried out under conditions sufficient to effect a radiant coil outlet temperature which is greater than the optimum radiant coil outlet temperature for cracking the synthetic crude oil separately. A method for upgrading synthetic crude for use in cracking is also provided, as well as a feedstock for cracking.
摘要翻译：一种用于蒸汽裂解含有合成原油的液体烃原料的方法包括：i）加氢处理宽沸点等分试样，其含有基本上不含残渣的通常为液体烃部分，和b）热裂化烃液体，沸点在600°至1050° F，提供基本上不含残渣的合成原油; ii）向合成原油中加入在100°F至1050°F范围内沸腾的常规液体烃组分; 和iii）在包含辐射线圈出口的裂化炉中裂解由ii）产生的混合物以提供裂化流出物，其中裂化在足以实现大于最佳辐射线圈出口的辐射盘管出口温度的条件下进行分别裂解合成原油的温度。还提供了用于提高用于裂化的合成粗品的方法以及用于裂化的原料。

54. 发明申请

WO2008051633A2 CROPPING SYSTEMS FOR MANAGING WEEDS 审中-公开
标题翻译：管理用品的制作系统
公开(公告)号：WO2008051633A2
公开(公告)日：2008-05-02
申请号：PCT/US2007/070510
申请日：2007-06-06
申请人： MONSANTO TECHNOLOGY LLC , ARNEVIK, Cindy, L. , BRINKER, Ronald, J. , ELMORE, Greg , GRAHAM, James, C. , SAMMONS, Robert, D. , STARKE, Michelle , VOTH, Richard, D.
发明人： ARNEVIK, Cindy, L. , BRINKER, Ronald, J. , ELMORE, Greg , GRAHAM, James, C. , SAMMONS, Robert, D. , STARKE, Michelle , VOTH, Richard, D.
IPC分类号： A01N27/00 , C12N15/82
CPC分类号： C12N15/8275 , A01N25/00 , A01N61/00 , A01N2300/00
摘要： The invention provides cropping systems for managing weeds in crop environments. The cropping systems comprise, in one embodiment, transgenic plants that display tolerance to an auxin-like herbicide such as dicamba. Method for minimizing the development of herbicide resistant weeds are also provided.
摘要翻译：本发明提供了在作物环境中管理杂草的作物系统。在一个实施方案中，种植系统包括显示对生长素样除草剂如麦草畏的耐受性的转基因植物。还提供了使除草剂抗性杂草的发展最小化的方法。

55. 发明申请

WO2007047941A3 RESID PROCESSING FOR STEAM CRACKER FEED AND CATALYTIC CRACKING 审中-公开
公开(公告)号：WO2007047941A3
公开(公告)日：2007-04-26
申请号：PCT/US2006/041069
申请日：2006-10-19
申请人： EXXONMOBIL CHEMICAL PATENTS INC. , BUCHANAN, John, S. , KEUSENKOTHEN, Paul, F. , BROWN, Stephen, H. , WOLFENBARGER, Julian, A. , GRAHAM, James, E. , MCCOY, James, N.
发明人： BUCHANAN, John, S. , KEUSENKOTHEN, Paul, F. , BROWN, Stephen, H. , WOLFENBARGER, Julian, A. , GRAHAM, James, E. , MCCOY, James, N.
IPC分类号： C10G69/00 , C10G69/02 , C10G69/04
摘要： The invention concerns integration of hydroprocessing and steam cracking. A feed comprising crude or resid-containing fraction thereof is treated by hydroprocessing and visbreaking and then the light fraction is passed to a steam cracker to obtain a product comprising olefins. The heavy fraction is then passed to a catalytic cracker.

56. 发明申请

WO2006020632A2 DIGITAL COLOR FIDELITY 审中-公开
标题翻译：数字色彩清晰度
公开(公告)号：WO2006020632A2
公开(公告)日：2006-02-23
申请号：PCT/US2005028255
申请日：2005-08-10
申请人： TRIBECA IMAGING LAB , BEVANS MICHAEL L , CHATTMAN BRADEN , GRAHAM JAMES
发明人： BEVANS MICHAEL L , CHATTMAN BRADEN , GRAHAM JAMES
IPC分类号： H04N1/46
CPC分类号： H04N1/6033 , H04N1/6086
摘要： A system and method manipulates and corrects the color of digital images. The invention addresses, inter alia, problem of the differences in chromaticity of two systems by characterizing the chromaticity of the hues of a color model to minimize the perceived color difference between a digital image and its real world counterpart.
摘要翻译：系统和方法操纵和校正数字图像的颜色。本发明特别地通过表征颜色模型的色调的色度来最小化数字图像与其真实世界对应物之间的感知色差来解决两个系统的色度差异的问题。

57. 发明申请

WO2004071710A2 DIAMOND TOOL INSERTS PRE-FIXED WITH BRAZE ALLOYS AND METHODS TO MANUFACTURE THEREOF 审中-公开
标题翻译：预先固定有钎焊合金的金刚石刀具插入物及其制造方法
公开(公告)号：WO2004071710A2
公开(公告)日：2004-08-26
申请号：PCT/US2004002398
申请日：2004-01-27
申请人： GEN ELECTRIC , ZIMMERMAN MICHAEL H , DYER DWIGHT E , MCHALE JAMES MICHAEL JR , RIES SCOTT ARLEN , GRAHAM JAMES D , FALKENBERG YORK , HEINEMANN DIRK
发明人： ZIMMERMAN MICHAEL H , DYER DWIGHT E , MCHALE JAMES MICHAEL JR , RIES SCOTT ARLEN , GRAHAM JAMES D , FALKENBERG YORK , HEINEMANN DIRK
IPC分类号： B23K3/06 , B23K20/16 , B23K35/02 , B23K35/30 , E21B10/56 , E21B10/573 , B24D
CPC分类号： C04B37/003 , B23K3/06 , B23K20/16 , B23K35/0244 , B23K35/3006 , B23K2201/40 , B32B2315/02 , C04B37/006 , C04B2235/945 , C04B2237/125 , C04B2237/36 , C04B2237/361 , C04B2237/363 , C04B2237/52 , C04B2237/708 , E21B10/573
摘要： A superabrasive tool blank whose carbide side is affixed with a suitable braze alloy, for subsequent shaping into desired tool geometry and induction-brazed forming a cutting tool. The use of the pre-coated braze alloy in the tool blank forming cutting tools allows the direct brazing of the superabrasive blank onto a tool insert, thus minimizing operations and labor time involved for the shaping and handling of the braze substrate in the process of the prior art, i.e., the brazing of the assembly of the superabrasive tool blank, braze alloy, and tool insert. The pre-brazed blank can be conveniently used in automated brazing operations for forming cutting tools.
摘要翻译：超硬磨料刀具坯料，其碳化物侧面附有合适的钎焊合金，用于随后成型为所需的刀具几何形状，并通过感应钎焊形成切削刀具。在工具毛坯成形切削工具中使用预涂布的铜焊合金允许将超级磨料毛坯直接钎焊到工具插入件上，从而最小化在钎焊衬底的成形和处理过程中涉及的操作和劳动时间现有技术，即超级磨具工具毛坯，铜焊合金和工具插件的组件的钎焊。预钎焊毛坯可方便地用于自动钎焊操作以形成切削工具。

58. 发明申请

WO1995031508A1 WAX COATED SILICA MATTING AGENT 审中-公开
标题翻译： WAX涂层二氧化硅处理剂
公开(公告)号：WO1995031508A1
公开(公告)日：1995-11-23
申请号：PCT/EP1995001431
申请日：1995-04-15
申请人： CROSFIELD LIMITED , ALDCROFT, Derek , EARL, Graham, James
发明人： CROSFIELD LIMITED
IPC分类号： C09C01/30
CPC分类号： C09C1/3063 , C01P2002/02 , C01P2004/51 , C01P2004/61 , C01P2004/84 , C01P2006/12 , C01P2006/14 , C01P2006/16 , C01P2006/17 , C01P2006/60 , C01P2006/80 , C09C1/3072 , C09D7/42
摘要： Wax coated silica matting agent wherein the silica is an amorphous silica having a pore size distribution wherein 90 % of the pores have a diameter above 15 nanometers, and less than 20 % of the pore volume is in pores having a pore diameter between 10 and 30 nanometers, the wax coating being present in the range from about 2 % to about 15 % by weight of the matting agent and comprising a hard microcrystalline wax, a plasticising microcrystalline wax, a synthetic polyethylene wax or a mixture thereof.
摘要翻译：蜡涂覆的二氧化硅消光剂，其中二氧化硅是具有孔径分布的无定形二氧化硅，其中90％的孔具有大于15纳米的直径，小于孔体积的20％是孔径在10和30之间的孔中纳米，蜡涂层以消光剂重量的约2％至约15％的范围存在，并且包含硬微晶蜡，增塑微晶蜡，合成聚乙烯蜡或其混合物。

59. 发明申请

WO1994006710A1 IMPROVEMENTS IN OR RELATING TO WINCHES 审中-公开
标题翻译：改善或相关于WINCHES
公开(公告)号：WO1994006710A1
公开(公告)日：1994-03-31
申请号：PCT/NZ1993000081
申请日：1993-09-09
申请人： MAXWELL WINCHES LIMITED , OWENS, Peter, Lewis , MARSH, Graham, James
发明人： MAXWELL WINCHES LIMITED
IPC分类号： B66D01/30
CPC分类号： B66D1/7431 , B66D1/7494
摘要： A winch (1) particularly suitable as a yacht sheet line winch. In traditional manner the winch (1) preferably incorporates a cylindrically shaped drum (2) having a shoulder lower end section (2a), in use, the drum (2) being intended to be rotated, such as by handle (10), about a substantially vertically disposed axis. Longitudinal or axially extending recesses (3) are incorporated at radially spaced apart intervals about the drum (2) with the land sections (4a) therebetween maintaining the radius of curvature of the drum (2). The recesses (3) provide additional frictional grip on a sheet line (8) retained thereon. Preferably the recesses (3) terminate in adjacent spaced relationship to a shoulder end (2a) to provide a recess free zone (6). The recesses (3) are configured to provide an obtuse angle between a face (4) of the drum (2) and the adjacent intersection face (5) of a recess (3) this "transition" angle being identified as angle "X" on the accompanying drawings. Preferably both the depth and width of the recesses (3) and the diameter of the drum increase toward a top of the drum (2). This geometry of the recess (3) configuration and layout on a drum (2) tends to spread the frictionnally forces provided thereby away from a first turn (7) of sheet line (8) on the drum (2).
摘要翻译：绞车（1）特别适合作为游艇板卷绞车。以传统的方式，绞车（1）优选地包括具有肩部下端部分（2a）的圆柱形鼓（2），在使用中，滚筒（2）旨在例如通过手柄（10）旋转，大约基本垂直设置的轴线。纵向或轴向延伸的凹部（3）围绕滚筒（2）以径向隔开的间隔结合，其间的陆部区段（4a）保持滚筒（2）的曲率半径。凹槽（3）在保持在其上的片材线（8）上提供额外的摩擦抓握。优选地，凹部（3）以与肩端（2a）相邻的间隔的关系终止以提供无凹槽区（6）。凹部（3）构造成在滚筒（2）的面（4）和凹部（3）的相邻交叉面（5）之间提供钝角，该“过渡角”被标识为角度“X” 在附图上。优选地，凹部（3）的深度和宽度以及鼓的直径朝向鼓（2）的顶部增加。在滚筒（2）上的凹槽（3）构型和布局的这种几何形状倾向于将由此提供的摩擦力扩展到远离卷筒（2）上的片材线（8）的第一匝（7）。

60. 发明申请

WO1992007205A1 VARIABLE CIRCUMFERENCE ADJUSTABLE-DRIVE PULLEY MECHANISM 审中-公开
标题翻译：可变循环可调速驱动机构
公开(公告)号：WO1992007205A1
公开(公告)日：1992-04-30
申请号：PCT/US1991006657
申请日：1991-09-16
申请人： GRAHAM, James, A.
IPC分类号： F16H55/00
CPC分类号： F16H55/54 , F16H55/38 , F16H55/56
摘要： A compact, reliable lightweight variable diameter drive mechanism for use with either a belt or a chain comprising outwardly biased, frusto-conical axially movable pulley halves (10) and an automatically adjustable, flexible contacting surface (22) wrapped around the pulley axle (12). The contacting surface is capable of imparting significant amounts of traction to the belt or the chain riding on the pulley halves. The contacting surface (22) automatically varies its circumference as the pulley diameter changes. Tension on the flexible contacting surface (22) is maintained by retracting one end into the hub of the pulley as the pulley halves (10) are axially adjusted.

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