专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

31. 发明申请

WO2004035109A2 APPARATUS AND METHODS FOR ACTIVATING A DELIVERY DEVICE 审中-公开
标题翻译：用于激活交付设备的装置和方法
公开(公告)号：WO2004035109A2
公开(公告)日：2004-04-29
申请号：PCT/US0332566
申请日：2003-10-15
申请人： DURECT CORP
发明人： BROWN JAMES E , GILLIS EDWARD M , POUTIATINE ANDREW I , KOLOSI WILLIAM D , FLOM JAMES R , THEEUWES FELIX
IPC分类号： A61B17/34 , A61K9/00 , A61M20060101 , A61M5/00 , A61M31/00 , A61M
CPC分类号： A61B17/3468 , A61K9/0024 , A61M37/0069
摘要： Devices and methods of actuating/activating agent delivery systems are provided. The subject devices include a trocar into which an agent delivery device is loaded in preparation for implantation of the agent delivery device into a patient. The action of loading the agent delivery device into the trocar serves to actuate or activate the device for the delivery of the agent which will commence upon implantation of the device. The methods include use of the trocar to actuate/activate the agent delivery device.
摘要翻译：提供了致动/激活剂递送系统的装置和方法。主体装置包括套管针，其中加载了药剂输送装置以准备将药剂输送装置植入患者体内。将药剂输送装置加载到套管针中的作用用于致动或激活装置，用于递送将在植入装置时开始的药剂。所述方法包括使用套管针来致动/激活药剂递送装置。

32. 发明申请

WO02062352A3 DEVICES AND METHODS FOR MANAGEMENT OF BONE DENSITY 审中-公开
标题翻译：用于骨密度管理的装置和方法
公开(公告)号：WO02062352A3
公开(公告)日：2003-04-03
申请号：PCT/US0203794
申请日：2002-02-07
申请人： DURECT CORP , CHAN TAI WAH
发明人： CHAN TAI WAH
IPC分类号： A61K9/22 , A61L26/00 , A61L27/18 , A61L27/54 , A61P19/10 , A61K9/00 , A61K31/663
CPC分类号： A61L27/54 , A61L26/0066 , A61L27/18 , A61L2300/112 , A61L2300/604 , C08L67/04
摘要： The invention features devices and methods for the delivery of a formulation to an individual to stabilize or increase bone mass by increasing bone deposition and/or decreasing bone resorption. In the present invention, a drug formulation comprising a bisphosphonate is provided parenterally in a sustained release dosage from, e.g., as an injected matrix or stored within a drug delivery device. In a specific embodiment, the dosage form may be implanted or injected into a site in the body (i.e., implantation site) and a conduit, e.g., a catheter, can be used to transport the formulation from the dosage form for release at a site in the body distal form the implantation site.
摘要翻译：本发明的特征在于通过增加骨沉积和/或减少骨吸收来将制剂递送至个体以稳定或增加骨量的装置和方法。在本发明中，包含双膦酸盐的药物制剂以例如作为注射基质的持续释放剂量肠胃外提供，或者存储在药物递送装置内。在一个具体的实施方案中，可以将剂型植入或注射到体内的位点（即，植入部位），并且导管（例如导管）可用于将制剂从剂型运送到位置释放在身体远端形成植入部位。

33. 发明申请

WO03009882A2 LOCAL CONCENTRATION MANAGEMENT SYSTEM 审中-公开
标题翻译：本地集中管理系统
公开(公告)号：WO03009882A2
公开(公告)日：2003-02-06
申请号：PCT/US0222813
申请日：2002-07-16
申请人： DURECT CORP , THEEUWES FELIX , YUM SU IL
发明人： THEEUWES FELIX , YUM SU IL
IPC分类号： A61M25/00 , A61M25/14 , A61M25/16 , A61M
CPC分类号： A61M25/00 , A61M25/0043 , A61M2025/0057 , A61M2025/105 , A61M2025/1086
摘要： The invention provides a local concentration management system (LCMS) for delivery of highly concentrated therapeutic agent formulations. The LCMS comprises a device comprising an elongate body defining a lumen between its proximal and distal ends, and a diffuser element, a dilutor element, or both. The diffuser element, which is selectively permeable to the agent, is operatively associated with the elongate body so that agent flows through the elongate body, and into and through the diffuser element to exit the system. The dilutor element can be operatively associated with the system to be in fluid communication with the elongate body lumen, a diffusion space defined by a diffuser element inner wall, or both. The dilutor element is selectively water permeable, but substantially impermeable to agent, to provide for dilution of the agent during transit through the system. The LCMS system is designed to disperse and/or dilute the drug delivery stream.
摘要翻译：本发明提供了用于递送高度浓缩的治疗剂制剂的局部浓度管理系统（LCMS）。 LCMS包括装置，其包括在其近端和远端之间限定内腔的细长主体，以及扩散器元件，稀释元件或两者。对试剂选择性渗透的扩散器元件可与细长体可操作地连接，使得试剂流过细长体并进入并通过扩散器元件以离开系统。稀释元件可以与系统可操作地相关联以与细长体腔流体连通，由扩散器元件内壁或两者限定的扩散空间。稀释剂元件选择性地是水可渗透的，但是对试剂基本上是不可渗透的，以便在通过系统运输期间提供试剂的稀释。 LCMS系统被设计成分散和/或稀释药物输送流。

34. 发明申请

WO03002170A2 MINIMALLY INVASIVE DRUG DELIVERY CATHETER 审中-公开
标题翻译：微量进入药物输送导管
公开(公告)号：WO03002170A2
公开(公告)日：2003-01-09
申请号：PCT/US0221945
申请日：2002-06-27
申请人： DURECT CORP , GILLIS EDWARD M
发明人： GILLIS EDWARD M
IPC分类号： A61M25/00 , A61M25/16 , A61M
CPC分类号： A61M25/008 , A61M25/0054 , A61M25/0068 , A61M25/0069 , A61M2025/0042 , A61M2210/0693
摘要： The catheter of the invention is of a design adapted to be implanted, and fixed in place, without the use of a trocar or cannula, such that tissue damage is minimized both at the time of implantation, and later, over the period that the catheter remains implanted. In one embodiment, the catheter may be used to deliver a drug over a prolonged period of time, to a precise location, for instance to treat an inoperative tumor of the brain stem. In another embodiment, the catheter of the invention may be implanted, and maintained in place and used to deliver repeated doses of a drug to the same target over time without the necessity of repeatedly re-implanting a needle through tissue to access the target site.
摘要翻译：本发明的导管的设计适于在不使用套管针或套管的情况下植入并固定就位，使得在植入时和随后在导管仍然植入。在一个实施例中，导管可用于将药物在延长的时间段内递送至精确的位置，例如用于治疗脑干的无功能肿瘤。在另一个实施例中，本发明的导管可以被植入并保持在适当的位置并用于随着时间的推移将重复剂量的药物递送到相同的目标，而不需要重复地重新植入针头穿过组织以进入目标部位。

35. 发明申请

WO0224159A3 IMPLANTABLE DRUG DELIVERY PATCH 审中-公开
标题翻译：可植入药物递送补丁
公开(公告)号：WO0224159A3
公开(公告)日：2002-10-10
申请号：PCT/US0129362
申请日：2001-09-19
申请人： DURECT CORP
发明人： THEEUWES FELIX , NELSON TIMOTHY S
IPC分类号： A61K9/00 , A61K9/70
CPC分类号： A61K9/0024 , A61K9/7084
摘要： The present invention features devices and methods for delivery of drug to an internal organ surface by delivery of drug directly to the surface of the organ such that the drug traverses the organ surface and enters the organ tissue. The device is in the form of an implantable drug delivery patch comprising a first layer, which is generally substantially drug-impermeable. When the first layer is placed on an outer surface of an organ, a drug reservoir is defined by the first layer and the organ surface.
摘要翻译：本发明的特征在于通过将药物直接递送至器官表面以使药物穿过器官表面并进入器官组织而将药物递送至内部器官表面的装置和方法。该装置是可植入药物递送贴片的形式，其包含通常基本上不透药的第一层。当第一层被放置在器官的外表面上时，药物储存器由第一层和器官表面限定。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式