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21. 发明申请

WO2006000997A2 IMAGING METHOD WITH BACK PROJECTION 审中-公开
标题翻译：具有后投影的成像方法
公开(公告)号：WO2006000997A2
公开(公告)日：2006-01-05
申请号：PCT/IB2005/052090
申请日：2005-06-24
申请人： PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KONINKLIJKE PHILIPS ELECTRONICS N.V. , NIELSEN, Tim , ZIEGLER, Andy , KOEHLER, Thomas , PROKSA, Roland
发明人： NIELSEN, Tim , ZIEGLER, Andy , KOEHLER, Thomas , PROKSA, Roland
IPC分类号： G06T15/00
CPC分类号： G06T11/006 , A61B6/027 , G06T2211/421 , Y10S378/901
摘要： The invention relates to an imaging method, especially a computerized tomography method, with which an object is penetrated by rays from different directions and measured values, which depend upon the intensity of the rays after penetrating the object, are acquired by a detector unit. From these measured values, an object image is reconstructed by means of back projection of measured-value-dependent back projection values. Therein, the object image is divided into overlapping, quasi-spherically symmetric image segments, each being defined by an image value and a quasi-spherically symmetric base function. Furthermore, during the back projection, the back projection values are added in proportions to the image values, wherein the proportion of a back projection value, which is added during the back projection to an image value, is dependent on a proportionality factor, which is equal to the average value of the line integrals of the base function belonging to the respective image value along those rays that have generated the measured value, on which the respective back projection value is dependent.
摘要翻译：本发明涉及一种成像方法，特别是计算机断层摄影方法，其中物体被来自不同方向的光线穿透，并且测量值取决于穿透物体之后的光线的强度，由检测器单元获取。从这些测量值，通过背投影测量值依赖的反投影值重建对象图像。其中，对象图像被划分为重叠的准球形对称图像片段，每个片段由图像值和准球形对称的基本功能定义。此外，在背投影期间，反投影值以与图像值成比例的方式相加，其中在后投影中添加的反投影值与图像值的比例取决于比例因子，即比例因子等于属于相应图像值的基本功能的线积分的平均值，沿着相应的背投影值依赖于已经产生测量值的那些射线。

22. 发明申请

WO2005088543A1 MOTION COMPENSATION 审中-公开
标题翻译：运动补偿
公开(公告)号：WO2005088543A1
公开(公告)日：2005-09-22
申请号：PCT/IB2005/050655
申请日：2005-02-23
申请人： PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KONINKLIJKE PHILIPS ELECTRONICS N.V. , KÖHLER, Thomas , GRASS, Michael , NIELSEN, Tim , KOKEN, Peter
发明人： KÖHLER, Thomas , GRASS, Michael , NIELSEN, Tim , KOKEN, Peter
IPC分类号： G06T11/00
CPC分类号： G06T11/006 , G06T2211/412
摘要： Using only projection data in one temporal gating window around a certain target phase point may lead to motion artifacts such as blurred images. By using projection data corresponding to three temporal gating windows, which are slightly shifted with respect to each other but at least partially overlap, motion within the gating window may be estimated and, according to an exemplary embodiment of the present invention, this estimation may be used for improving the image quality. Advantageously, only the projection data inside the at least partially overlapping gating windows are used for reconstruction and motion compensation.
摘要翻译：在某个目标相位点周围的一个时间门控窗口中仅使用投影数据可能会导致运动伪影，如模糊图像。通过使用对应于相对于彼此略微偏移但至少部分重叠的三个时间门控窗口的投影数据，可以估计门控窗口内的运动，并且根据本发明的示例性实施例，该估计可以是用于提高图像质量。有利地，仅将至少部分重叠的门控窗口内的投影数据用于重建和运动补偿。

23. 发明申请

WO2013038283A1 METHOD OF IMAGE RECONSTRUCTION FOR A FILTERED BACK PROJECTION IN LIMITED ANGLE TOMOGRAPHY 审中-公开
标题翻译：用于有角度角度扫描的过滤背投影的图像重建方法
公开(公告)号：WO2013038283A1
公开(公告)日：2013-03-21
申请号：PCT/IB2012/054367
申请日：2012-08-27
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GmbH , NIELSEN, Tim , HITZIGER, Sebastian , GRASS, Michael
发明人： NIELSEN, Tim , HITZIGER, Sebastian , GRASS, Michael
IPC分类号： G06T11/00
CPC分类号： G06T11/006 , A61B6/035 , G06T2210/41 , G06T2211/421 , G06T2211/436
摘要： The present invention is directed to a limited angle tomography in combination with a filtered back projection using a special filter operator X. The filter operator X used within the present invention makes it possible to perform region of interest reconstructions although delivering high quality reconstruction images as generated by high effort S ART methods. The used filter operator is purely and solely mathematically determined and defined by the spatial geometry which is used for the limited angle tomography. Without having the need to perform several iterations, the present invention directly calculates a solution, i.e. reconstructed image, equivalent to known iteratively construction methods. Although, incomplete projection data p may only be used, the present invention provides for a high image quality.
摘要翻译：本发明涉及一种与使用特殊滤波器操作器X的滤波反投影相结合的有限角度断层摄影。本发明中使用的滤波器操作器X可以执行感兴趣的重建区域，尽管传送高质量的重建图像产生通过高素质的S ART方法。所使用的过滤器操作员纯粹且仅在数学上由用于有限角度层析成像的空间几何形状来确定和限定。在不需要进行多次迭代的情况下，本发明直接计算与已知的迭代构造方法相当的解，即重构图像。尽管可以仅使用不完全的投影数据p，但是本发明提供了高图像质量。

24. 发明申请

WO2011042820A1 RETROSPECTIVE CALCULATION OF RADIATION DOSE AND IMPROVED THERAPY PLANNING 审中-公开
标题翻译：辐射剂量的改进计算和改进的治疗方案
公开(公告)号：WO2011042820A1
公开(公告)日：2011-04-14
申请号：PCT/IB2010/054189
申请日：2010-09-16
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , NIELSEN, Tim , BOERNERT, Peter , UHLEMANN, Falk , OVERWEG, Johannes, Adrianus
发明人： NIELSEN, Tim , BOERNERT, Peter , UHLEMANN, Falk , OVERWEG, Johannes, Adrianus
IPC分类号： G01R33/381 , G01R33/48 , A61N5/10 , A61B5/055
CPC分类号： A61N5/1071 , A61N5/1031 , A61N5/1039 , A61N5/1049 , A61N2005/1055 , A61N2005/1058 , G01R33/3806 , G01R33/381 , G01R33/4808 , G01R33/5601
摘要： A combined magnetic resonance (MR) and radiation therapy system (10) includes a bore-type magnet (12) with a magnet radiation translucent region (16) which allows radiation beams to travel radially through the magnet and a split-type gradient coil (18) includes a gradient coil radiation translucent region (20) aligned to the magnet radiation translucent region (16). A radiation source (24), disposed laterally to the magnet, administers a radiation dose through the magnet and gradient coil radiation translucent regions (16, 20) to an examination region (14). A dosage unit (66) determines the actual radiation dose delivered to each voxel of a target volume (30) and at least one non-target volume based on a pre-treatment, intra-treatment, and/or post-treatment image representation of the target volume (30) and the at least one non-target volume. A planning processor (60) updates at least one remaining radiation dose of a radiation therapy plan based on the determined actual radiation dose.
摘要翻译：组合磁共振（MR）和放射治疗系统（10）包括具有磁体辐射半透明区域（16）的孔型磁体（12），其允许辐射束径向穿过磁体和分离式梯度线圈 18）包括与磁体辐射半透明区域（16）对准的梯度线圈辐射半透明区域（20）。辐射源（24）横向设置在磁体上，通过磁体和梯度线圈辐射半透明区域（16,20）将辐射剂量施加到检查区域（14）。剂量单元（66）基于预处理，治疗前和/或后处理图像表示来确定递送到目标体积（30）的每个体素的实际辐射剂量和至少一个非目标体积目标体积（30）和至少一个非目标体积。计划处理器（60）基于所确定的实际辐射剂量更新辐射治疗计划的至少一个剩余辐射剂量。

25. 发明申请

WO2009150568A1 METHOD OF DETECTING PROBLEMS, DEVICE FOR IMAGING THE INTERIOR OF TURBID MEDIA AND COMPUTER PROGRAM PRODUCT 审中-公开
标题翻译：检测问题的方法，用于成像涡轮介质和计算机程序产品内部的装置
公开(公告)号：WO2009150568A1
公开(公告)日：2009-12-17
申请号：PCT/IB2009/052319
申请日：2009-06-02
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , BRENDEL, Bernhard, J. , NIELSEN, Tim
发明人： BRENDEL, Bernhard, J. , NIELSEN, Tim
IPC分类号： A61B5/00
CPC分类号： A61B5/4312 , A61B5/0091
摘要： A method of detecting technical problems in a device for imaging the interior of turbid media. The method is for a device comprising: a receiving portion for receiving a turbid medium to be examined; and at least one light source and at least one detector being optically connected to the receiving portion such that a plurality of different combinations of source postition and detector position defining different light paths through the receiving portion. The method comprises :a turbid media measurement step; the measurement step generates a plurality of measurement data values corresponding to a plurality of different light paths through the receiving portion; and a processing step for analyzing if technical problems have occurred during the measurement step. The processing step comprises: comparing the measurement data values to corresponding reference data values from a reference measurement with the receiving portion filled with an optically matching medium.
摘要翻译：一种检测用于对浑浊介质内部进行成像的装置中的技术问题的方法。该方法用于包括：接收部分，用于接收待检查的混浊介质; 以及至少一个光源和至少一个检测器光学地连接到接收部分，使得源极定位和检测器位置的多个不同组合限定穿过接收部分的不同光路。该方法包括：浊度介质测量步骤; 所述测量步骤通过所述接收部分生成对应于多个不同光路的多个测量数据值; 以及用于分析在测量步骤期间是否已经发生技术问题的处理步骤。处理步骤包括：将测量数据值与参考测量值相对应的参考数据值与填充有光学匹配介质的接收部分进行比较。

26. 发明申请

WO2007107909A1 A DEVICE FOR IMAGING A TURBID MEDIUM 审中-公开
标题翻译：一种用于成像涡轮介质的装置
公开(公告)号：WO2007107909A1
公开(公告)日：2007-09-27
申请号：PCT/IB2007/050804
申请日：2007-03-12
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , NIELSEN, Tim , GROSENICK, Dirk , RINNEBERG, Herbert, H. , STEINKELLNER, Oliver, H.
发明人： NIELSEN, Tim , GROSENICK, Dirk , RINNEBERG, Herbert, H. , STEINKELLNER, Oliver, H.
IPC分类号： A61B5/00
CPC分类号： A61B5/4312 , A61B5/0073 , A61B5/0091
摘要： The present invention relates to a device for imaging a turbid medium (130, 132; 184) comprising: means (110; 134, 138, 140, 142, 144, 146) for optically scanning a predefined maximum area of a scanning plane (102; 104) for acquisition of imaging data, - means (134, 136; 206, 208, 210) for detection of an outer contour of the turbid medium, means (112, 120, 122) for controlling the optical scanning such that a sub-area of the maximum area is scanned that is smaller than the maximum area and that covers the outer contour.
摘要翻译：本发明涉及一种用于对浑浊介质（130,132; 184）成像的装置，包括：用于光学扫描扫描平面（102）的预定义最大区域的装置（110; 134,138,140,142,144,146） ; 104），用于获取成像数据， - 用于检测所述混浊介质的外轮廓的装置（134,136; 206,208,210），用于控制所述光学扫描的装置（112,120,122），使得子 - 扫描最大面积的面积小于最大面积，并覆盖外轮廓。

27. 发明申请

WO2005036466A1 ITERATIVE DATA RECONSTRUCTION 审中-公开
标题翻译：迭代数据重构
公开(公告)号：WO2005036466A1
公开(公告)日：2005-04-21
申请号：PCT/IB2004/051962
申请日：2004-10-04
申请人： PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KONINKLIJKE PHILIPS ELECTRONICS N.V. , NIELSEN, Tim , KÖHLER, Thomas
发明人： NIELSEN, Tim , KÖHLER, Thomas
IPC分类号： G06T11/00
CPC分类号： G06T11/006 , G06T2211/424
摘要： Iterative algorithms which may be used for image reconstruction, consisting of alternating projections and backprojections usually have a slow convergence, due to correlations between simultaneously processed data and consequently a low image quality. According to the present invention, a filtering step is introduced before backprojection, allowing a parallel processing without the loss of convergence speed or image quality. Advantageously, this may allow to perform several projections/backprojections simultaneously.
摘要翻译：由于交替的投影和反向投影组成的可用于图像重建的迭代算法通常具有缓慢的收敛，这是由于同时处理的数据与因此的低图像质量之间的相关性。根据本发明，在反投影之前引入滤波步骤，允许并行处理而不会失去收敛速度或图像质量。有利地，这可以允许同时执行若干投影/反投影。

28. 发明申请

WO2004079444A2 DEVICE AND METHOD FOR THE SELECTIVE AMPLIFICATION OF PHOTONS IN A TIME WINDOW 审中-公开
标题翻译：时间窗口中选择性放大光子的装置和方法
公开(公告)号：WO2004079444A2
公开(公告)日：2004-09-16
申请号：PCT/IB2004/000555
申请日：2004-03-03
申请人： PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KONINKLIJKE PHILIPS ELECTRONICS N.V. , NIELSEN, Tim , KRÜGER, Sascha
发明人： NIELSEN, Tim , KRÜGER, Sascha
IPC分类号： G02F1/35
CPC分类号： H01S3/1022 , A61B5/0071 , A61B5/0073 , A61B5/0086 , A61B5/7285 , A61B6/541 , G01N21/4795 , G02F1/39 , G02F2203/26
摘要： The invention relates to a method for the selective amplification of signal photons of a signal pulse (4) in a desired time window. For this purpose, the signal photons (4) are passed through an activated amplification medium (1), where amplification takes place by induced emissions. The amplification is terminated at a desired point in time by the irradiation of a quench pulse (7). Optionally, the start of amplification can be determined by an irradiated pump pulse (8). Emissions that are not correlated with the signal pulse (4) can be suppressed by means of a spectral filter (2). Furthermore, an intensity filter such as a saturable absorber (3) can suppress unamplified fractions of the emission (5) leaving the amplification medium (1). Applications of the method include medical optical imaging and tomography by transillumination with time-gated detection of ballistic photons.
摘要翻译：本发明涉及一种在期望的时间窗口中选择性地放大信号脉冲（4）的信号光子的方法。为此，信号光子（4）通过激活的放大介质（1），其中通过诱导的发射进行放大。通过骤冷脉冲（7）的照射，在期望的时间点终止放大。可选地，放大开始可以通过照射的泵浦脉冲（8）来确定。可以通过光谱滤波器（2）来抑制与信号脉冲（4）不相关的发射。此外，诸如可饱和吸收体（3）的强度滤波器可以抑制离开放大介质（1）的发射（5）的未扩增分数。该方法的应用包括医学光学成像和断层扫描，通过时间门控检测弹道光子。

29. 发明申请

WO2013038284A1 GENERATING A THREE-DIMENSIONAL MODEL FROM AN OBJECT OF INTEREST 审中-公开
标题翻译：从兴趣对象中产生三维模型
公开(公告)号：WO2013038284A1
公开(公告)日：2013-03-21
申请号：PCT/IB2012/054368
申请日：2012-08-27
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GmbH , ERHARD, Klaus , GRASS, Michael , NIELSEN, Tim , BUELOW, Thomas
发明人： ERHARD, Klaus , GRASS, Michael , NIELSEN, Tim , BUELOW, Thomas
IPC分类号： A61B5/00 , A61B6/00 , G01N21/47 , G06T11/00
CPC分类号： A61B5/0073 , A61B5/0035 , A61B5/0091 , A61B6/4417 , A61B6/502 , A61B6/5247 , G06F19/00 , G16H50/50
摘要： For generating a three-dimensional model (60) from an object of interest optical tomography raw data acquired from the object and X-ray image data acquired from the object (50) is used to select a reference model of the object (18) from a plurality of reference models based on the X-ray image data and the optical tomography raw data. The three- dimensional model is generated from the reference model by adjusting the reference model to the X-ray image data.
摘要翻译：为了从感兴趣对象生成三维模型（60），从对象获取的原始数据和从对象（50）获取的X射线图像数据用于从对象（18）获取的原始数据和从对象（50）获得的X射线图像数据，从基于X射线图像数据和光学层析成像原始数据的多个参考模型。通过将参考模型调整到X射线图像数据，从参考模型生成三维模型。

30. 发明申请

WO2012153250A1 BREAST CANCER RISK ASSESSMENT 审中-公开
标题翻译：乳腺癌风险评估
公开(公告)号：WO2012153250A1
公开(公告)日：2012-11-15
申请号：PCT/IB2012/052242
申请日：2012-05-04
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , GRASS, Michael , ERHARD, Klaus , NIELSEN, Tim
发明人： GRASS, Michael , ERHARD, Klaus , NIELSEN, Tim
IPC分类号： A61B6/00 , G06T7/00 , G06F19/00
CPC分类号： A61B6/502 , A61B6/025 , A61B6/0414 , A61B6/4452 , A61B6/463 , A61B6/486 , A61B6/5217 , A61B6/5235 , A61B6/5294 , G06F19/00 , G06F19/321 , G06T7/0014 , G06T2207/10116 , G06T2207/30068 , G16H40/63 , G16H50/20
摘要： The present invention relates to breast cancer screening. In order to improve the detection rate in breast cancer screening and to enhance cancer risk assessment, according to the present invention, first image data (202) of a breast of a patient is provided (201); and second image data (204) of a breast of the patient. The first image data and the second image data are registered (205) and non-congruency (207) between the breast of the first image data and the breast of the second image data is determined (206). The non-congruency information (209) is provided (208) to the user. For example, the first and second image data are 3D image data sets. According to an example, the non-congruency information is provided as multivariate non-congruency information indicating at least two measured non-congruency parameters. According to a further example, the non-congruency is determined based on parameters related to the breast tissue as well as breast tissue unrelated parameters.
摘要翻译：本发明涉及乳腺癌筛查。为了提高乳腺癌筛查中的检出率和增强癌症风险评估，根据本发明，提供了患者乳房的第一图像数据（202）（201）。和第二图像数据（204）。确定第一图像数据和第二图像数据（205），并且确定第一图像数据的乳房和第二图像数据的乳房之间的非一致性（207）（206）。非一致性信息（209）被提供给用户（208）。例如，第一和第二图像数据是3D图像数据集。根据一个示例，非一致性信息被提供为指示至少两个测量的非一致性参数的多变量非一致性信息。根据另一个实例，基于与乳房组织相关的参数以及乳腺组织无关参数确定非一致性。

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