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21. 发明申请

WO2010061328A1 VISUALIZATION OF THE CORONARY ARTERY TREE 审中-公开
标题翻译：冠状动脉瘤的可视化
公开(公告)号：WO2010061328A1
公开(公告)日：2010-06-03
申请号：PCT/IB2009/055220
申请日：2009-11-20
申请人： PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KONINKLIJKE PHILIPS ELECTRONICS N. V. , HANSIS, Eberhard, S. , GRASS, Michael
发明人： HANSIS, Eberhard, S. , GRASS, Michael
IPC分类号： A61B6/00 , G06T11/00
CPC分类号： A61B6/504 , A61B6/4441 , A61B6/466 , A61B6/481 , A61B6/541 , G06T11/006 , G06T2211/404
摘要： The present invention is related to a method for reconstruction of the coronary arteries and an examination apparatus for reconstruction of the coronary arteries. To provide improved coronary artery information, an apparatus and a method are provided where a gating signal is provided (32) and a first gated X-ray image sequence of one of the left or right branches of the coronary arteries is acquired (34) with injected contrast agent into the one of the left or right branches of the coronary arteries. Further, a second gated X-ray image sequence of the other branch of the coronary arteries is acquired (36) with injected contrast agent into said other branch. Then, a gated reconstructing (38) of the left and the right coronary artery is suggested and a volume data (40, 42) of the coronary arteries is generated. The volume data of the left and right coronary arteries is registered (44) in relation to time and space. Further; the registered volume data (48, 50) of the left and the right coronary arteries is combined and a combined coronary artery tree volume data set (52) is generated (54). Finally, the combined coronary tree volume data set is visualized (56).
摘要翻译：本发明涉及冠状动脉重建方法和冠状动脉重建检查装置。为了提供改善的冠状动脉信息，提供了一种装置和方法，其中提供门控信号（32），并且获取冠状动脉的左分支或右分支之一的第一门控X射线图像序列（34），其中将注射的造影剂注射到冠状动脉的左侧或右侧分支中。此外，冠状动脉的另一个分支的第二选通X射线图像序列（36）被注入造影剂获取到所述另一分支中。然后，建议左冠状动脉和右冠状动脉的门控重建（38），并且产生冠状动脉的体积数据（40,42）。左冠状动脉和右冠状动脉的体积数据相对于时间和空间被记录（44）。进一步; 组合左冠状动脉和右冠状动脉的记录体数据（48,50），并且生成组合冠状动脉树体积数据组（52）（54）。最后，组合冠状动脉树体数据集可视化（56）。

22. 发明申请

WO2010041201A1 ANGIOGRAPHIC IMAGE ACQUISITION SYSTEM AND METHOD WITH AUTOMATIC SHUTTER ADAPTATION FOR YIELDING A REDUCED FIELD OF VIEW COVERING A SEGMENTED TARGET STRUCTURE OR LESION FOR DECREASING X-RADIATION DOSE IN MINIMALLY INVASIVE X-RAY-GUIDED INTERVENTIONS 审中-公开
标题翻译：具有自动切换器适应性的图像摄影系统和方法用于屏蔽减少的视野范围在微小的X射线引导干预中减少X辐射剂量的分离的目标结构或损伤
公开(公告)号：WO2010041201A1
公开(公告)日：2010-04-15
申请号：PCT/IB2009/054381
申请日：2009-10-07
申请人： PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KONINKLIJKE PHILIPS ELECTRONICS N. V. , GRASS, Michael , SCHAEFER, Dirk , SCHOONENBERG, Gert, A., F.
发明人： GRASS, Michael , SCHAEFER, Dirk , SCHOONENBERG, Gert, A., F.
IPC分类号： A61B6/00 , A61B6/06
CPC分类号： G06T11/008 , A61B6/06 , A61B6/4441 , A61B6/481 , A61B6/504 , A61B6/5247 , A61B6/542 , G06F19/00 , G06F19/321 , G06T15/08 , G06T2211/404 , G16H40/63
摘要： The present invention refers to an angiographic image acquisition system and method which can beneficially be used in the scope of minimally invasive image-guided interventions. In particular, the present invention relates to a system and method for graphically visualizing a pre-interventionally virtual 3D representation of a patient's coronary artery tree's vessel segments in a region of interest of a patient's cardiovascular system to be three-dimensionally reconstructed. Optionally, this 3D representation can then be fused with an intraoperatively acquired fluoroscopic 2D live image of an interventional tool. According to the present invention, said method comprises the steps of subjecting the image data set of the 3D representation associated with the precalculated optimal viewing angle to a 3D segmentation algorithm (S4) in order to find the contours of a target structure or lesion to be examined and interventionally treated within a region of interest and automatically adjusting (S5) a collimator wedge position and/or aperture of a shutter mechanism used for collimating an X-ray beam emitted by an X-ray source of a C-arm-based 3D rotational angiography device or rotational gantry-based CT imaging system to which the patient is exposed during an image-guided radiographic examination procedure based on data obtained as a result of said segmentation which indicate the contour and size of said target structure or lesion. The aim is to reduce the region of interest to a field of view that covers said target structure or lesion together with a user-definable portion of the sorrounding vasculature.
摘要翻译：本发明涉及一种血管造影图像采集系统和方法，可有利地用于微创图像引导干预的范围。特别地，本发明涉及一种用于以图形方式可视化患者心血管系统感兴趣区域中的患者冠状动脉树血管段的预先介入虚拟3D表示以进行三维重构的系统和方法。可选地，该3D表示随后可以与介入工具的术中获取的荧光透视2D实况图像融合。根据本发明，所述方法包括以下步骤：将与预先计算的最佳视角相关联的3D表示的图像数据集进行3D分割算法（S4），以便找出目标结构或病变的轮廓为在感兴趣区域内进行检查和介入处理，并自动调整（S5）用于准直由基于C臂的3D的X射线源发射的X射线束的快门机构的准直器楔位置和/或孔径旋转血管造影装置或基于旋转台架的CT成像系统，其中基于由所述分割结果获得的指示所述目标结构或病变的轮廓和大小的图像引导放射线检查程序期间所述患者暴露于所述CT成像系统。目的是将感兴趣的区域减少到涵盖所述目标结构或病变的视野以及可疑的部分的迷路脉管系统。

23. 发明申请

WO2009112998A1 MODEL BASED SELF-POSITIONING PATIENT TABLE FOR X- RAY SYSTEMS 审中-公开
标题翻译：基于模型的X射线系统自定位患者表
公开(公告)号：WO2009112998A1
公开(公告)日：2009-09-17
申请号：PCT/IB2009/050958
申请日：2009-03-09
申请人： PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KONINKLIJKE PHILIPS ELECTRONICS N. V. , SCHMITT, Holger , VAN STEVENDAAL, Udo , FORTHMANN, Peter , GRASS, Michael
发明人： SCHMITT, Holger , VAN STEVENDAAL, Udo , FORTHMANN, Peter , GRASS, Michael
IPC分类号： A61B6/00 , A61B6/04
CPC分类号： A61B6/0457 , A61B6/4441 , A61B6/465 , A61B6/469 , A61B6/488 , A61B6/547
摘要： A System (24) for positioning a carrier (9) of an object (10) within a field of view of an imaging unit (7b), the system comprising: -an imaging receiving interface unit (14) for receiving image data (22) representing an image (9) of the object (10) from an imaging unit (7b), -an object components position determination unit (15) for determining object components (11, 12) position data (25) representing positions of components (11, 12) of the object (10), -a memory(16) with anatomic model data stored therein, the anatomic model data representing anatomic model (9*) component positions of anatomic model components (11*, 12*) of an atomic model (10*), -a matching unit (17) designed to match object components (11, 12) positions and anatomic model components (11*, 12*) positions based on object components position data and anatomic model data, -an input receiving unit (19) for receiving input data (23) representing a selected component (11) of interest, -a positioning planning unit (18)for determining position shift data representing a direction and a distance by which the carrier (8) is to be shifted, considering the input data, anatomic model data and object components position data, -an interface (20) to a positioning system (21) for shifting the carrier (8) based on the position shift data (27).
摘要翻译：一种用于将物体（10）的载体（9）定位在成像单元（7b）的视野内的系统（24），所述系统包括： - 成像接收接口单元（14），用于接收图像数据（22））表示来自成像单元（7b）的对象（10）的图像（9）， - 对象分量位置确定单元（15），用于确定表示分量位置的对象分量（11,12）位置数据（25）（10）的存储器（16），存储有解剖模型数据的存储器（16），解剖模型数据表示解剖模型组件（11 *，12 *）的解剖模型（9 *）组件位置原子模型（10 *）， - 匹配单元（17），其被设计为基于对象分量位置数据和解剖模型数据来匹配对象分量（11,12）位置和解剖模型分量（11 *，12 *）位置，输入接收单元（19），用于接收表示所选择的所选择的组件（11）的输入数据（23）， - 定位计划单元（18），用于考虑输入数据，解剖模型数据和对象分量位置数据，确定表示载体（8）要移位的方向和距离的位置移位数据， - 到定位系统（21）的接口（20），用于基于位置偏移数据（27）移动载体（8）。

24. 发明申请

WO2009024894A3 PROJECTION-BASED REMOVAL OF HIGH-CONTRAST OBJECTS 审中-公开
公开(公告)号：WO2009024894A3
公开(公告)日：2009-02-26
申请号：PCT/IB2008/053229
申请日：2008-08-12
申请人： PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KONINKLIJKE PHILIPS ELECTRONICS N. V. , JANDT, Uwe , SCHAEFER, Dirk , GRASS, Michael
发明人： JANDT, Uwe , SCHAEFER, Dirk , GRASS, Michael
IPC分类号： G06T7/00
摘要： A system (900) and method for automatic projection-based removing of high-contrast artificial objects from a medical image is provided. The method comprises performing a low-pass filtering (1100) to the two-dimensional image (100, 500, 1000) using a filter width range (1110) corresponding to structures of a line-shaped artificial object to generate a low-pass filtered intensity image and performing an evaluation of the Hessian matrix of each pixels of the low-pass filtered intensity image for locating and enhancing the structure of the line-shaped artificial object to generate a multi-scale filtered intensity image, wherein predefined scaling widths are used in order to avoid the locating and enhancing of larger structures.

25. 发明申请

WO2007072279A1 ITERATIVE IMAGE RECONSTRUCTION OF A MOVING OBJECT FROM PROJECTION DATA 审中-公开
标题翻译：投影数据移动对象的迭代图像重构
公开(公告)号：WO2007072279A1
公开(公告)日：2007-06-28
申请号：PCT/IB2006/054700
申请日：2006-12-08
申请人： PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KONINKLIJKE PHILIPS ELECTRONICS N. V. , NIELSEN, Tim , GRASS, Michael , ZIEGLER, Andy
发明人： NIELSEN, Tim , GRASS, Michael , ZIEGLER, Andy
IPC分类号： G06T11/00
CPC分类号： G06T11/006 , G06T2211/412 , G06T2211/424
摘要： Iterative methods for reconstructing an image sequence of a moving object based on projection data usually require a high computationally effort. According to embodiments of the present invention there is provided such a method wherein a first image representing the object at a first phase is used as an initial image for iteratively reconstructing a second image at a second phase. A first gating function is assigned to the first phase, a second gating function is assigned to the second phase. When executing a first iteration for reconstructing the second image only projection data corresponding to a non- overlapping part of the two gating functions are used. For executing further iterations the amount of projection data corresponding to the overlapping part of the two gating functions may be gradually increased. Therefore, for all further but the last iteration the computationally effort is significantly reduced. However, this low computationally expense has no negative impact on the quality of the finally reconstructed second image because the method benefits from the fact that the first image was used as the initial image for iteratively reconstructing the second image.
摘要翻译：基于投影数据重建移动物体的图像序列的迭代方法通常需要较高的计算量。根据本发明的实施例，提供了这样的方法，其中将表示第一阶段的对象的第一图像用作用于在第二阶段迭代重建第二图像的初始图像。第一门控功能被分配给第一阶段，第二门控功能被分配给第二阶段。当执行用于重建第二图像的第一迭代时，仅使用与两个门控功能的非重叠部分相对应的投影数据。为了执行进一步的迭代，对应于两个门控功能的重叠部分的投影数据的量可以逐渐增加。因此，对于所有进一步但最后的迭代，计算量的努力显着降低。然而，这种低的计算费用对最终重建的第二图像的质量没有负面影响，因为该方法受益于第一图像被用作用于迭代重建第二图像的初始图像的事实。

26. 发明申请

WO2005057491A1 IMAGE SEGMENTATION IN A VOLUME DATA SET 审中-公开
标题翻译：体积数据集中的图像分割
公开(公告)号：WO2005057491A1
公开(公告)日：2005-06-23
申请号：PCT/IB2004/052569
申请日：2004-11-26
申请人： PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KONINKLIJKE PHILIPS ELECTRONICS N. V. , BUELOW, Thomas , GRASS, Michael , LORENZ, Christian , MANZKE, Robert
发明人： BUELOW, Thomas , GRASS, Michael , LORENZ, Christian , MANZKE, Robert
IPC分类号： G06T5/00
CPC分类号： G06T7/11 , G06T2207/10081 , G06T2207/30101
摘要： Coronary artery segmentation is a crucial task in cardiac CT image processing. This is often a tedious task performed manually by an operator. According to the present invention, a method is provided which combines data from multiple cardiac phases during the segmentation process in order to deliver a complete and continuous coronary vessel tree. Advantageously, this may allow for an improved visualization and segmentation of vessels, for example, in coronary CTA.
摘要翻译：冠状动脉分割是心脏CT图像处理中的关键任务。这通常是由操作员手动执行的繁琐的任务。根据本发明，提供了一种在分割过程中组合来自多个心脏相的数据以递送完整且连续的冠状动脉血管树的方法。有利地，这可以允许例如在冠状动脉CTA中改善血管的可视化和分割。

27. 发明申请

WO2008107816A1 ITERATIVE RECONSTRUCTION OF CORONARY ARTERIES 审中-公开
标题翻译：冠状动脉重建术
公开(公告)号：WO2008107816A1
公开(公告)日：2008-09-12
申请号：PCT/IB2008/050695
申请日：2008-02-27
申请人： PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KONINKLIJKE PHILIPS ELECTRONICS N. V. , HANSIS, Eberhard, Sebastian , GRASS, Michael , SCHÄFER, Dirk
发明人： HANSIS, Eberhard, Sebastian , GRASS, Michael , SCHÄFER, Dirk
IPC分类号： G06T11/00 , G06T5/00
CPC分类号： G06T5/008 , G06T5/002 , G06T5/30 , G06T11/005 , G06T11/006 , G06T2211/424
摘要： According to an exemplary embodiment of the present invention, an iterative reconstruction of coronary arteries comprises a filtering of projection data on the basis of a top-hat filter and an iterative reconstruction of the object of interest on the basis of a regularisation favouring sparse objects. This may provide for high contrast and detail.
摘要翻译：根据本发明的示例性实施例，冠状动脉的迭代重建包括基于顶帽过滤器和基于有利于稀疏对象的正则化的感兴趣对象的迭代重建的投影数据的过滤。这可以提供高对比度和细节。

28. 发明申请

WO2007072286A2 METHOD FOR MOVEMENT COMPENSATION OF IMAGE DATA 审中-公开
标题翻译：运动补偿图像数据的方法
公开(公告)号：WO2007072286A2
公开(公告)日：2007-06-28
申请号：PCT/IB2006/054727
申请日：2006-12-11
申请人： PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KONINKLIJKE PHILIPS ELECTRONICS N. V. , GRASS, Michael , KOEHLER, Thomas
发明人： GRASS, Michael , KOEHLER, Thomas
IPC分类号： G06T11/00
CPC分类号： A61B6/032 , A61B6/541 , G06T11/005 , G06T2211/412
摘要： According to an exemplary embodiment a method for movement compensation of image data of an object of interest comprises receiving projection data, receiving motion vector field data, and dividing the motion vector field data into a number of layers of motion vector field data. Furthermore, the method comprises generating motion compensated projection data by projecting at least one of the number of layered motion vector field data onto the projection data and applying a two dimensional motion compensation on the projection, and generating image data of at least one voxel by back-projecting the movement compensated projection data.
摘要翻译：根据示例性实施例，一种用于感兴趣对象的图像数据的运动补偿的方法包括：接收投影数据;接收运动矢量场数据;以及将运动矢量场数据分成多个层运动矢量场数据。此外，该方法包括通过将多个分层运动矢量场数据中的至少一个投影到投影数据上并且对投影应用二维运动补偿并且通过后部生成至少一个体素的图像数据来生成运动补偿投影数据 - 投影移动补偿投影数据。

29. 发明申请

WO2007060572A2 MOTION COMPENSATED CT RECONSTRUCTION OF HIGH CONTRAST OBJECTS 审中-公开
标题翻译：高对比度对象的运动补偿CT重建
公开(公告)号：WO2007060572A2
公开(公告)日：2007-05-31
申请号：PCT/IB2006/054232
申请日：2006-11-14
申请人： PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KONINKLIJKE PHILIPS ELECTRONICS N. V. , GRASS, Michael , SCHAEFER, Dirk , VAN STEVENDAAL, Udo
发明人： GRASS, Michael , SCHAEFER, Dirk , VAN STEVENDAAL, Udo
IPC分类号： G06T7/00 , G06T11/00 , A61B5/00
CPC分类号： A61B6/032 , A61B6/027 , A61B6/12 , A61B6/541 , G06T7/20 , G06T11/006 , G06T2207/10081 , G06T2207/30048 , G06T2211/412
摘要： Cardiac CT imaging using gated reconstruction is currently limited in its temporal and spatial resolution. According to an exemplary embodiment of the present invention, an examination apparatus is provided in which an identification of a high contrast object is performed. This high contrast object is then followed through the phases, resulting in a motion vector field of the high contrast object, on the basis of which a motion compensated reconstruction is then performed.
摘要翻译：使用门控重建的心脏CT成像目前在其时间和空间分辨率上受到限制。根据本发明的示例性实施例，提供了一种检查装置，其中执行高对比度对象的识别。然后这个高对比度物体在相位中跟随，产生高对比度物体的运动矢量场，在此基础上进行运动补偿重建。

30. 发明申请

WO2004093684A1 GERÄT FÜR DIE ANGIOGRAPHISCHE RÖNTGEN-BILDGEBUNG 审中-公开
标题翻译： DEVICE血管造影X射线成像
公开(公告)号：WO2004093684A1
公开(公告)日：2004-11-04
申请号：PCT/IB2004/050476
申请日：2004-04-21
申请人： PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KONINKLIJKE PHILIPS ELECTRONICS N. V. , SCHMITT, Holger , GRASS, Michael , RASCHE, Volker
发明人： SCHMITT, Holger , GRASS, Michael , RASCHE, Volker
IPC分类号： A61B6/00
CPC分类号： A61B6/481 , A61B6/4441 , A61B6/504
摘要： Die Erfindung betrifft ein Röntgen-Bildgebungsgerät zur Visualisierung des Blutflusses in einem koronaren Gefäßbaum eines Patienten. Es wird gemäß der Erfindung ein erster Satz (1) von Röntgenprojektionsbildern des Gefäßbaumes in verschiedenen Phasen des Herzzyklus unter gleichzeitiger Aufzeichnung des EKG's (2) des Patienten aufgenommen. Sodann erfolgt mittels einer geeigneten Programmsteuerung von Computermitteln (17) des erfindungsgemäßen Gerätes eine Rekonstruktion der dreidimensionalen Struktur des Gefäßbaumes in den verschiedenen Phasen des Herzzyklus. Ein zweiter Satz (6) von Röntgenprojektionsbildern wird während der Gabe eines Kontrastmittels, wiederum unter Aufzeichnung des EKG's (7), aufgenommen. Die Erfindung schlägt zur Bestimmung der zeitabhängigen Kontrastmittelkonzentration innerhalb der rekonstruierten dreidimensionalen Struktur des Gefäßbaumes vor, einzelnen Gefäßsegmenten (5, 8) zugeordnete lokale Bildbereiche innerhalb der Röntgenprojektionsbilder des zweiten Satzes (6) entsprechend den räumlichen Positionen der Gefäßsegmente (5, 8) in der betreffenden Phase des Herzzyklus aufzufinden. Die Ermittlung der Kontrastmittelkonzentration im Bereich der Gefäßsegmente (5, 8) erfolgt dann durch Auswertung der Röntgenabsorbtion innerhalb der aufgefundenen lokalen Bildbereiche.
摘要翻译：本发明涉及一种X射线成像装置用于在患者的冠状血管树中的血液流动的可视化。它是按照本发明采取的，在心动周期的不同阶段的血管树的X射线投影图像中的第一组（1）用ECG的同时记录（2）病人的。然后，通过计算机的合适的程序的控制手段根据本发明的血管树的三维结构在心动周期的不同阶段的重构装置的装置（17）。 X射线投影图像的第二组（6）的造影剂的给药过程中被记录时，再次记录ECG（7）。本发明提出以确定所述血管树中，每个容器的段的重构的三维结构内依赖于时间的造影剂浓度（5,8）与（6）对应于所述血管段的在相应的空间位置（8 5），第二组的x射线投影图像中的局部图像区域相关联的发现心动周期的相位。然后造影剂浓度的血管段的区域中的确定（5,8）由所述发现局部图像区域内评估Röntgenabsorbtion。

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