专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

21. 发明申请

WO2008022205A3 THYROXINE-CONTAINING COMPOUND ANALYSIS METHODS 审中-公开
公开(公告)号：WO2008022205A3
公开(公告)日：2008-02-21
申请号：PCT/US2007/076016
申请日：2007-08-15
申请人： APPLERA CORPORATION , PURKAYASTHA, Subhasish
发明人： PURKAYASTHA, Subhasish
IPC分类号： G01N33/78 , G01N33/68
摘要： The present teachings provide methods for analyzing one or more thyroxine compounds in one or more samples using isobaric labels and parent-daughter ion transition monitoring (PDITM). In various embodiments, the methods comprise the steps of: (a) labeling one or more thyroxine compounds with different isobaric tags from a set of isobaric tags, each isobaric tag comprising a reporter ion portion; (b) combining at least a portion of each of the isobarically labeled thyroxine compounds to produce a combined sample; (c) subjecting at least a portion of the combined sample to PDITM; (d) measuring the ion signal of one or more of the transmitted reporter ions; and (e) determining the concentration of one or more of the isobarically labeled thyroxine compounds based at least on a comparison of the measured ion signal of the corresponding reporter ion to one or more measured ion signals of a standard compound.

22. 发明申请

WO2007087534A3 METHODS, MIXTURES, KITS AND COMPOSITIONS PERTAINING TO ANALYTE DETERMINATION 审中-公开
标题翻译：用于分析物测定的方法，混合物，试剂盒和组合物
公开(公告)号：WO2007087534A3
公开(公告)日：2007-11-29
申请号：PCT/US2007060921
申请日：2007-01-23
申请人： APPLERA CORP , PILLAI SASI K , DEY SUBHAKAR , PURKAYASTHA SUBHASISH , PAPPIN DARRYL J C
发明人： PILLAI SASI K , DEY SUBHAKAR , PURKAYASTHA SUBHASISH , PAPPIN DARRYL J C
IPC分类号： G01N24/00
CPC分类号： C07D295/15 , C07D403/12 , G01N33/58 , G01N33/6848
摘要： This invention pertains to methods, mixtures, kits and compositions pertaining to analyte determination by mass spectrometry.
摘要翻译：本发明涉及与通过质谱法测定分析物有关的方法，混合物，试剂盒和组合物。

23. 发明申请

WO2007087534A2 METHODS, MIXTURES, KITS AND COMPOSITIONS PERTAINING TO ANALYTE DETERMINATION 审中-公开
标题翻译：方法，混合物，用于分析确定的组合物和组合物
公开(公告)号：WO2007087534A2
公开(公告)日：2007-08-02
申请号：PCT/US2007/060921
申请日：2007-01-23
申请人： APPLERA CORPORATION , PILLAI, Sasi, K. , DEY, Subhakar , PURKAYASTHA, Subhasish , PAPPIN, Darryl, J.C.
发明人： PILLAI, Sasi, K. , DEY, Subhakar , PURKAYASTHA, Subhasish , PAPPIN, Darryl, J.C.
IPC分类号： A61K31/165
CPC分类号： C07D295/15 , C07D403/12 , G01N33/58 , G01N33/6848
摘要： This invention pertains to methods, mixtures, kits and compositions pertaining to analyte determination by mass spectrometry.
摘要翻译：本发明涉及通过质谱法分析物测定的方法，混合物，试剂盒和组合物。

24. 发明申请

WO2006086540A1 AMINE-CONTAINING COMPOUD ANALYSIS METHODS 审中-公开
标题翻译：含氨的组合分析方法
公开(公告)号：WO2006086540A1
公开(公告)日：2006-08-17
申请号：PCT/US2006/004548
申请日：2006-02-09
申请人： APPLERA CORPORATION , NIMKAR, Subodh, B. , PURKAYASTHA, Subhasish , PAPPIN, Darryl , DANIELS, Scott
发明人： NIMKAR, Subodh, B. , PURKAYASTHA, Subhasish , PAPPIN, Darryl , DANIELS, Scott
IPC分类号： G01N33/68
CPC分类号： G01N33/6848 , Y10T436/142222 , Y10T436/173845 , Y10T436/24
摘要： The present teachings provide methods for analyzing one or more amine-containing compounds in one or more samples using isobaric labels and parent-daughter ion transition monitoring (PDITM). In various embodiments, the methods comprise the steps of: (a) labeling one or more amine-containing compounds with different isobaric tags from a set of isobaric tags, each isobaric tag comprising a reporter ion portion; (b) combining at least a portion of each of the isobarically labeled amine-containing compounds to produce a combined sample; (c) subjecting at least a portion of the combined sample to PDITM; (d) measuring the ion signal of one or more of the transmitted reporter ions; and (e) determining the concentration of one or more of the isobarically labeled amine-containing compounds based at least on a comparison of the measured ion signal of the corresponding reporter ion to one or more measured ion signals of a standard compound.
摘要翻译：本教导提供了使用等压标记和亲 - 子离子跃迁监测（PDITM）在一个或多个样品中分析一种或多种含胺化合物的方法。在各种实施方案中，所述方法包括以下步骤：（a）从一组等压标签组合标记具有不同等压标签的一种或多种含胺化合物，每个同量异位标签包含报告离子部分; （b）将每个等压标记的含胺化合物的至少一部分合并以产生组合的样品; （c）使组合样品的至少一部分经受PDITM; （d）测量一个或多个所传递的报道离子的离子信号; 至少基于相应报道离子的测量离子信号与标准化合物的一个或多个测量离子信号的比较来确定一种或多种等压标记的含胺化合物的浓度。

25. 发明申请

WO2005068446A1 LABELING REAGENTS, LABELED ANALYTES, INCLUDING MIXTURES THEREOF, AND FRAGMENT IONS DERIVED THEREFROM AND METHODS FOR THE ANALYSIS THEREOF 审中-公开
标题翻译：标签试剂，标签分析，包括其混合物，以及衍生的片段离子及其分析方法
公开(公告)号：WO2005068446A1
公开(公告)日：2005-07-28
申请号：PCT/US2005/000223
申请日：2005-01-05
申请人： APPLERA CORPORATION , DEY, Subhakar , PAPPIN, Darryl, J.C. , PURKAYASTHA, Subhasish , PILLAI, Sasi , COULL, James, M.
发明人： DEY, Subhakar , PAPPIN, Darryl, J.C. , PURKAYASTHA, Subhasish , PILLAI, Sasi , COULL, James, M.
IPC分类号： C07D295/03
CPC分类号： C07D207/46 , C07D241/08 , C07D253/08 , C07D295/03 , C07D295/15
摘要： This invention pertains to labeling reagents, labeled analytes, including mixtures thereof, and fragment ions derived therefrom. This invention also pertains to methods for the production of labeling reagents, including N-substituted piperazine acetic acid based labeling reagents, labeled analytes, including mixtures thereof, and fragment ions derived therefrom as well as methods of the analysis of the labeled analytes.
摘要翻译：本发明涉及标记试剂，标记分析物，包括它们的混合物，以及衍生自其的碎片离子。本发明还涉及生产标记试剂的方法，包括基于N-取代的哌嗪乙酸的标记试剂，标记的分析物，包括其混合物，以及衍生自其的片段离子以及分析标记的分析物的方法。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式