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    • 25. 发明申请
    • THERAPEUTIC COMPOSITION CONTAINING ENDOTHELIN AS AN ACTIVE COMPONENT
    • 含有内皮素作为活性成分的治疗组合物
    • WO2012138043A2
    • 2012-10-11
    • PCT/KR2011010320
    • 2011-12-29
    • SEOUL NAT UNIV HOSPITALLEE EUN JUKIM HYO SOO
    • LEE EUN JUKIM HYO SOO
    • A61K31/19A61P9/00A61P9/10
    • A61K38/2278
    • The present invention relates to a composition for preventing or treating ischemic disease comprising endothelin or a nucleotide sequence encoding endothelin as an active ingredient, and more particularly to a composition for preventing or treating ischemic heart disease, myocardial infarction, angina pectoris, lower limb artery ischemia, distal limb ischemia and ischemic cerebrovascular disease, wherein the composition is administered by intramuscular injection. According to the present invention, administering endothelin-1 by intramuscular injection may efficiently inhibit the progress of ischemia, fibrosis and tissue necrosis, and induce angiogenesis, such that it is promising for preventing or treating the ischemic disease.
    • 本发明涉及用于预防或治疗缺血性疾病的组合物,其包含内皮素或编码内皮素作为活性成分的核苷酸序列,更具体地涉及用于预防或治疗缺血性心脏病,心肌梗死,心绞痛,下肢动脉缺血的组合物 ,远端肢体缺血和缺血性脑血管疾病,其中所述组合物通过肌内注射施用。 根据本发明,通过肌内注射给予内皮素-1可有效抑制缺血,纤维化和组织坏死的进展,并诱导血管发生,从而有希望预防或治疗缺血性疾病。
    • 26. 发明申请
    • SECONDARY BATTERY HAVING A DIFFERENTIAL LEAD STRUCTURE
    • 二次电池具有不同的引线结构
    • WO2012011716A3
    • 2012-05-03
    • PCT/KR2011005293
    • 2011-07-19
    • LG CHEMICAL LTDLEE EUN-JUSHIN YOUNG-JOON
    • LEE EUN-JUSHIN YOUNG-JOON
    • H01M2/30
    • H01M2/30H01M2/0212
    • A secondary battery having a differential lead structure according to one aspect of the present invention comprises: an electrode assembly including a positive electrode plate having a positive electrode tap, a negative electrode plate having a negative electrode tap, and a separation layer interposed between the positive electrode plate and the negative electrode plate; a battery case receiving the electrode assembly; a positive electrode lead electrically connected to the positive electrode tap; and a negative electrode lead formed of a different material from that of the positive electrode lead and electrically connected to the negative electrode tap. Each of the positive electrode lead and the negative electrode lead has a mutually different sectional area. The sectional area of a lead having low electrical conductivity is greater than that of a lead having high electrical conductivity.
    • 根据本发明的一个方面的具有差动引线结构的二次电池包括:电极组件,其包括具有正极抽头的正极板,具有负极抽头的负极板以及介于正极板之间的分离层 电极板和负极板; 接收电极组件的电池壳体; 电连接到正电极抽头的正电极引线; 以及由与正极引线的材料不同的材料形成的负电极引线并且电连接到负电极抽头。 每个正电极引线和负电极引线具有彼此不同的截面面积。 具有低导电率的引线的截面积大于具有高导电率的引线的截面积。