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1. 发明申请

WO2021158013A1 HYDROGEL AND METHOD FOR PREPARING THE SAME 审中-公开
公开(公告)号：WO2021158013A1
公开(公告)日：2021-08-12
申请号：PCT/KR2021/001419
申请日：2021-02-03
申请人： KOREA ATOMIC ENERGY RESEARCH INSTITUTE
发明人： PARK, Sang-Hyun , RAZA, Muhammad Asim
IPC分类号： A61K9/06 , A61K47/36 , A61K47/24 , A61K31/43 , A61K31/7036 , A61K51/12
摘要： The present disclosure provides a hydrogel having excellent drug delivery ability and having antibacterial properties as well as pH-dependent, biocompatible and biodegradable properties, and a method for preparing the same. The hydrogel including radiated chitosan, a natural gelling polymer, a hydrophilic synthetic polymer and (3-mercaptopropyl)trimethoxysilane (MPTMS), and the method for preparing the same are provided.

2. 发明申请

WO2018217001A1 COOLING FACILITY IN A REACTOR VESSEL AND ELECTRIC POWER GENERATION SYSTEM 审中-公开
公开(公告)号：WO2018217001A1
公开(公告)日：2018-11-29
申请号：PCT/KR2018/005827
申请日：2018-05-23
申请人： KOREA ATOMIC ENERGY RESEARCH INSTITUTE , KING ABDULLAH CITY FO ATOMIC AND RENEWABLE ENERGY
发明人： KIM, Youngin , RYU, Seungyeob , MOON, Joohyung , SHIN, Soojai , KIM, Seok , CHO, Hyunjun , YOON, Juhyeon , KWON, Kilsung
IPC分类号： G21D5/02 , G21C9/016 , G21C15/18
摘要： An in-vessel cooling and power generation system according to the present disclosure may include a small scale reactor vessel, a heat exchange section provided inside the reactor vessel, and formed to supply supercritical fluid to receive heat from a reactor coolant system in the reactor vessel, an electric power production section comprising a supercritical turbine formed to produce electric energy using the energy of the supercritical fluid whose temperature has increased while receiving heat from the reactor coolant system, a cooling section configured to exchange heat with the supercritical fluid discharged after driving the supercritical turbine to shrink a volume of the supercritical fluid, wherein the supercritical fluid that has received heat from the reactor coolant system in the heat exchange section is formed to circulate through the electric power production section, and the cooling section. The in-vessel cooling and power generation system according to the present disclosure may be continuously operated not only during a normal operation but also during an accident to perform in-vessel cooling, and produce emergency power, thereby improving the system reliability. In addition, the in-vessel cooling and power generation system according to the present disclosure may facilitate the application of a safety class or seismic design with a small scale facility, thereby improving the reliability due to the application of the safety class or seismic design.

3. 发明申请

WO2016013738A1 A METHOD FOR MANUFACTURING CARBON ELECTRODE BY RADIATION 审中-公开
标题翻译：通过辐射制造碳电极的方法
公开(公告)号：WO2016013738A1
公开(公告)日：2016-01-28
申请号：PCT/KR2015/000248
申请日：2015-01-09
申请人： KOREA ATOMIC ENERGY RESEARCH INSTITUTE
发明人： KANG, Phil-Hyun , OH, Seung-Hwan , KIM, Kyu Ri , KIM, Hyun Bin
IPC分类号： H01B13/00 , H01B5/14 , H01B1/04
CPC分类号： H01B1/04 , H01M4/88 , H01M4/96
摘要： The present invention relates to a method for manufacturing carbon electrode comprising the following steps: drawing carbon electrode pattern on the upper substrate (step 1); and irradiating the carbon electrode pattern drawn in step 1 (step 2). In the method for manufacturing carbon electrode of the present invention, the carbon electrode is fixed on the substrate by irradiation, by which the conductivity of the carbon electrode can be also increased. The carbon electrode pattern can be fabricated by drawing with a carbon material such as pencil lead, suggesting that the preparation process is very simple.
摘要翻译：碳电极制造方法技术领域本发明涉及碳电极的制造方法，其特征在于，包括以下步骤：在上基板上拉制碳电极图案（工序1）。并照射步骤1中绘制的碳电极图案（步骤2）。在本发明的碳电极的制造方法中，通过照射将碳电极固定在基板上，由此碳电极的导电性也可以增加。碳电极图案可以通过用诸如铅笔等碳材料的拉伸来制造，这表明制备过程非常简单。

4. 发明申请

WO2015102159A1 PET-MRI DEVICE AND MANUFACTURING METHOD THEREOF 审中-公开
标题翻译： PET-MRI装置及其制造方法
公开(公告)号：WO2015102159A1
公开(公告)日：2015-07-09
申请号：PCT/KR2014/002602
申请日：2014-03-27
申请人： KOREA ATOMIC ENERGY RESEARCH INSTITUTE
发明人： HA, Jang Ho , KIM, Han Soo , KIM, Young Soo , JEONG, Man Hee , YEO, Sun Mog
IPC分类号： A61B5/055
CPC分类号： G01T1/2985 , A61B5/0035 , A61B5/055 , A61B6/037 , G01R33/28 , G01R33/381
摘要： A PET-MRI device and a manufacturing method thereof are disclosed. The PET device includes a magnetic resonance imaging (MRI) machine comprising a solenoid coil and a magnetic-field correction coil, wherein the MRI machine has a cylindrical structure or a dipole structure; and a positron emission tomography (PET) machine comprising a PET image sensor, wherein PET image sensor electrodes are formed on one and the other ends of the PET image sensor that have a doughnut shape, and the PET machine has a cylindrical structure or a lattice structure, wherein the PET machine is formed in the MRI machine to allow a direction of an electric field of the PET machine to be parallel to a direction of a magnetic field of the MRI machine.
摘要翻译：公开了一种PET-MRI装置及其制造方法。 PET装置包括磁共振成像（MRI）机，其包括螺线管线圈和磁场校正线圈，其中所述MRI机器具有圆柱形结构或偶极结构; 以及包括PET图像传感器的正电子发射断层摄影（PET）机器，其中PET图像传感器电极形成在具有环形形状的PET图像传感器的一端和另一端上，并且PET机器具有圆柱形结构或晶格结构，其中PET机器形成在MRI机器中以允许PET机器的电场的方向平行于MRI机器的磁场的方向。

5. 发明申请

WO2014065510A1 NOVEL ROTENONE DERIVATIVES AND A USE THEREOF 审中-公开
标题翻译：新型罗丹酮衍生物及其用途
公开(公告)号：WO2014065510A1
公开(公告)日：2014-05-01
申请号：PCT/KR2013/008487
申请日：2013-09-23
申请人： KOREA ATOMIC ENERGY RESEARCH INSTITUTE
发明人： CHUNG, Byung Yeoup , KIM, Tae Hoon , LEE, Seung Sik , BAI, Hyoungwoo , LEE, Sungbeom , PARK, Chul Hong
IPC分类号： C07D493/14 , C07D493/20 , A61K31/537 , A61P3/04
CPC分类号： C07D493/22 , A61K31/537 , B01J19/08 , C07D493/14 , C07D493/20
摘要： The present invention relates to a novel rotenone derivative and a use of the same. Particularly, the present inventors identified the novel rotenoisin A and B which were the compounds with no toxicity and prepared by irradiation with gamma ray onto rotenone represented by the following formula 1 and further confirmed that the novel rotenone derivative significantly inhibited pancreatic lipase activity and preadipocyte differentiation. The novel rotenone derivative of the present invention can be effectively used as a composition for the prevention and treatment of obesity and as a composition for health functional food for the prevention and improvement of obesity: [Formula 1] (In formula 1, R1 and R2 are as defined in this description).
摘要翻译：本发明涉及一种新颖的鱼藤酮衍生物及其用途。特别地，本发明人鉴定了作为无毒性化合物的新型罗非鱼素A和B，其通过用γ射线照射到由下式1表示的鱼藤酮上制备，并进一步证实该新型鱼藤酮衍生物显着抑制胰脂肪酶活性和前脂肪细胞分化。本发明的新颖的鱼藤酮衍生物可以有效地用作预防和治疗肥胖的组合物，并且作为用于预防和改善肥胖症的健康功能性食品的组合物：[式1]（式1中R1和R2 如本说明书中所定义）。

6. 发明申请

WO2013172616A1 PREPARATION OF TECHNETIUM-99M TRICARBONYL LABELED GLYCINE MONOMER OR OLIGOMER CONTAINING PROBES THAT HAVE BIOMOLECULES AND ITS APPLICATION AS IMAGING COMPLEX-COMPOSITION 审中-公开
标题翻译：制备具有生物分子和其应用于成像复合组成物的探针的99％三溴苯乙烯标记的甘油单体或低聚物
公开(公告)号：WO2013172616A1
公开(公告)日：2013-11-21
申请号：PCT/KR2013/004232
申请日：2013-05-13
申请人： KOREA ATOMIC ENERGY RESEARCH INSTITUTE
发明人： JANG, Beom Su , PARK, Sang Hyun , LEE, Joo-Sang , RHO, Jong-Kook
IPC分类号： A61K49/04 , A61K49/12 , A61K49/08
CPC分类号： A61K51/082 , A61K51/025 , A61K51/0406 , A61K51/085 , A61K51/088 , C07B59/001 , C07B2200/05 , C07C227/16 , C07K1/13 , C07K5/0806 , C07K7/06
摘要： Disclosed is a technetium-99m-labeled glycine oligomer associated with imaging probes for biomolecules of interest. The glycine oligomer can be readily synthesized in a single process using an automated peptide synthesizer. The technetium-99m tricarbonyl-labeled glycine oligomers can be useful as a radiotracer for gamma or SPECT imaging apparatus. The technetium-99m tricarbonyl-labeled glycine oligomers can be applied to various peptidyl biomolecules such as RGD peptide, somatostatin, neurotensin, etc., and exhibit rapid renal clearance without being excessively retained within the body.
摘要翻译：公开了与感兴趣的生物分子的成像探针相关的锝-99m标记的甘氨酸低聚物。甘氨酸低聚物可以使用自动化肽合成仪在单一过程中容易地合成。锝-99m三羰基标记的甘氨酸低聚物可用作γ或SPECT成像装置的放射性示踪剂。锝-99m三羰基标记的甘氨酸低聚物可以应用于各种肽基生物分子如RGD肽，生长抑素，神经降压素等，并且显示出快速的肾清除，而不会过度保留在体内。

7. 发明申请

WO2009151160A1 METHOD FOR MANUFACTURING THE COLOR CONTROLLED SAPPIRE 审中-公开
标题翻译：制造颜色控制SAPPIRE的方法
公开(公告)号：WO2009151160A1
公开(公告)日：2009-12-17
申请号：PCT/KR2008/003268
申请日：2008-06-12
申请人： KOREA ATOMIC ENERGY RESEARCH INSTITUTE , PARK, Jae-Won , AHN, Ju-Hyung , KIM, Young-chool , HAN, Jang-Min , KIM, Junyeon
发明人： PARK, Jae-Won , AHN, Ju-Hyung , KIM, Young-chool , HAN, Jang-Min , KIM, Junyeon
IPC分类号： C30B29/20 , C30B33/02
CPC分类号： C30B31/22 , C30B29/20 , C30B33/02
摘要： Disclosed herein is a method of manufacturing a color-controlled sapphire, comprising: vaporizing a metal material, irradiating the vaporized metal material with electron beams or high-frequency waves to form the vaporized metal material into a plasma state, and then implanting the metal ions into a sapphire by extracting the metal ions from the plasma and accelerating the metal ions (step 1); and heat-treating the sapphire implanted with the metal plasma ions in an oxygen atmosphere or in air (step 2). According to the method of manufacturing a sapphire of the present invention, a sapphire, which can exhibit various colors, can be manufactured by implanting the ions, which can cause optical band gap changes into the sapphire, and a sapphire, which cannot be damaged by radiation and can exhibit colors uniformly, can be manufactured by conducting heat treatment under an oxygen atmosphere. Further, according to the present invention, a sapphire, which cannot be damaged by radiation and can be made to exhibit uniform colors, can be manufactured by performing the above processes repeatedly.
摘要翻译：本发明公开了一种制造颜色控制蓝宝石的方法，包括：蒸发金属材料，用电子束或高频波照射蒸发的金属材料，以将蒸发的金属材料形成等离子体状态，然后注入金属离子通过从等离子体中提取金属离子并加速金属离子而成为蓝宝石（步骤1）; 并在氧气氛或空气中热处理注入金属等离子体离子的蓝宝石（步骤2）。根据本发明的制造蓝宝石的方法，可以通过将能够引起光学带隙变化的离子注入到蓝宝石中来制造能够呈现各种颜色的蓝宝石，并且不会被损坏的蓝宝石可以均匀地显示颜色，可以通过在氧气氛下进行热处理来制造。此外，根据本发明，可以通过重复执行上述处理来制造不能被辐射损坏并且可以制成呈现均匀颜色的蓝宝石。

8. 发明申请

WO2008069426A1 HIGH TEMPERATURE AND HIGH PRESSURE CORROSION RESISTANT PROCESS HEAT EXCHANGER FOR A NUCLEAR HYDROGEN PRODUCTION SYSTEM 审中-公开
标题翻译：一种核氢生产系统的高温高压耐腐蚀工艺热交换器
公开(公告)号：WO2008069426A1
公开(公告)日：2008-06-12
申请号：PCT/KR2007/004939
申请日：2007-10-10
申请人： KOREA ATOMIC ENERGY RESEARCH INSTITUTE , KOREA HYDRO & NUCLEAR POWER CO., LTD. , KIM, Yongwan , PARK, Jaewon , KIM, Minhwan , HONG, Sungdeok , LEE, Wonjae , CHANG, Jonghwa
发明人： KIM, Yongwan , PARK, Jaewon , KIM, Minhwan , HONG, Sungdeok , LEE, Wonjae , CHANG, Jonghwa
IPC分类号： G21D9/00
CPC分类号： G21D9/00 , C01B3/06 , F28D9/0062 , F28D15/00 , F28F3/025 , F28F19/02 , F28F21/08 , Y02E60/364
摘要： A high-temperature and high-pressure corrosion-resistant process heat exchanger for a nuclear hydrogen production system decomposes sulfite (SO 3 ) using heat from a high-temperature gas-cooled reactor to thereby produce sulfide (SO 2 ) and oxygen (O 2 ). The process heat exchanger comprises second and third system coolant channels, each of which is defined by a heat transmission fin, which is bent in a quadrilateral shape, and heat transmission plates, and has increased corrosion resistance thanks to ion-beam coating and ion-beam mixing using a material having high corrosion resistance. The third system coolant channel includes reaction catalysts for SO 3 decomposition, and is made of a super alloy. Thus, a system differential pressure between the second and third system coolant channels can be greatly maintained at a high temperature of 900°C or higher.
摘要翻译：用于核氢生产系统的高温和高压耐腐蚀工艺热交换器使用来自高温气冷反应堆的热分解亚硫酸盐（SO 3 N 3），从而产生硫化物（SO 2 O 2）和氧（O 2 H 2）。过程热交换器包括第二和第三系统冷却剂通道，每个通道由四边形弯曲的传热翅片和传热板限定，并且由于离子束涂覆和离子束涂覆而具有增加的耐腐蚀性，使用具有高耐腐蚀性的材料进行光束混合。第三系统冷却剂通道包括用于SO 3分解的反应催化剂，并且由超级合金制成。因此，可以在900℃以上的高温下极大地维持第二和第三系统冷却剂通道之间的系统压差。

9. 发明申请

WO2007111416A1 METHOD OF PRODUCING CHITOSAN SCAFFOLD HAVING HIGH TENSILE STRENGTH AND CHITOSAN SCAFFOLD PRODUCED USING THE METHOD 审中-公开
标题翻译：生产使用该方法生产的具有高拉伸强度的CHITOSAN SCAFFOLD和CHITOSAN SCAFFOLD的方法
公开(公告)号：WO2007111416A1
公开(公告)日：2007-10-04
申请号：PCT/KR2007/000908
申请日：2007-02-21
申请人： KOREA ATOMIC ENERGY RESEARCH INSTITUTE , KIM, Chun-Ho , LEE, Seung-Jae , LIM, Jin-Ik , SON, Youngsook , KIM, Keun-Woo , GIN, Yong-Jae
发明人： KIM, Chun-Ho , LEE, Seung-Jae , LIM, Jin-Ik , SON, Youngsook , KIM, Keun-Woo , GIN, Yong-Jae
IPC分类号： C12N5/00 , A61L27/60
CPC分类号： C12N5/0068 , A61L15/28 , A61L15/425 , A61L27/20 , A61L27/56 , C12N2533/18 , C12N2533/50 , C12N2533/52 , C12N2533/54 , C12N2533/70 , C12N2533/72 , C12N2533/74 , C08L5/08
摘要： Provided are a method of producing a porous chitosan scaffold, the method including: providing an aqueous acidic solution having chitosan and a solvent which does not dissolve the chitosan; and freeze-drying the aqueous acidic solution, wherein the solvent is selected from the group consisting of a C3-C8 aliphatic alcohol having one hydroxy group, ethylene glycol monoethylether, ethylene glycol monobutylether, dioxane, tetrahydrofuran, dimethylcarbonate, acetone and acetonitrile, and a chitosan scaffold produced using the method.
摘要翻译：提供一种生产多孔壳聚糖支架的方法，该方法包括：提供具有壳聚糖的水性酸性溶液和不溶解壳聚糖的溶剂; 并冷冻干燥酸性水溶液，其中溶剂选自具有一个羟基的C 3 -C 8脂族醇，乙二醇单乙醚，乙二醇单丁醚，二恶烷，四氢呋喃，碳酸二甲酯，丙酮和乙腈，和使用该方法生产壳聚糖支架。

10. 发明申请

WO2007043762A1 A NEUTRON COINCIDENCE COUNTER FOR NON-DESTRUCTIVE ACCOUNTING FOR NUCLEAR MATERIAL AND THE HANDLING METHOD THEREOF 审中-公开
标题翻译：核材料非破坏性会计核算计数器及其处理方法
公开(公告)号：WO2007043762A1
公开(公告)日：2007-04-19
申请号：PCT/KR2006/003941
申请日：2006-09-29
申请人： KOREA ATOMIC ENERGY RESEARCH INSTITUTE , KOREA HYDRO & NUCLEAR POWER CO., LTD , LEE, Tae Hoon , KIM, Ho Dong , KO, Won Il , SONG, Dae Yong , JEONG, Joong Hwan , LEE, Sang Yoon
发明人： LEE, Tae Hoon , KIM, Ho Dong , KO, Won Il , SONG, Dae Yong , JEONG, Joong Hwan , LEE, Sang Yoon
IPC分类号： G21K1/00
CPC分类号： G01T3/00 , G01T7/02
摘要： A neutron coincidence counter for non-destructive accounting for a nuclear material according to the present invention comprises an outer case, neutron detectors mounted in the outer case while being surrounded by a moderator, and a basket horizontally movable in the outer case so as to be exposed outside the outer case and having a cavity for receiving a sample container therein. Further, a neutron coincidence counter for non-destructive accounting for a nuclear material according to the present invention comprises an outer case, neutron detectors mounted in the outer case while being surrounded by a moderator, a basket movable in the outer case so as to be exposed outside the outer case and having a cavity for receiving a sample container therein, and an external signal analyzer connected to the detectors through an electrically conductive path. Moreover, at least one facile connector of one-touch connection type is mounted on the electrically conductive path for connecting the detectors to the external signal analyzer, resulting in free removal and replacement of wires connected to the connector.
摘要翻译：根据本发明的用于核材料的非破坏性核算的中子重合计数器包括外壳，安装在外壳中并由主体包围的中子探测器和可在外壳中水平移动的篮状物暴露在外壳外部并且具有用于在其中接收样品容器的空腔。此外，根据本发明的用于核材料的非破坏性核算的中子重合计数器包括外壳，安装在外壳中同时由调节器包围的中子探测器，可在外壳中移动的篮状物暴露在外壳外部并且具有用于在其中接收样品容器的空腔和通过导电路径连接到检测器的外部信号分析器。此外，至少一个轻触式连接器的简单连接器安装在导电路径上，用于将检测器连接到外部信号分析仪，从而免除了去除和更换连接到连接器的电线。

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