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21. 发明申请

WO2006001768A1 COLLISION DETECTING DEVICE AND METHOD 审中-公开
标题翻译：碰撞检测装置和方法
公开(公告)号：WO2006001768A1
公开(公告)日：2006-01-05
申请号：PCT/SE2005/000991
申请日：2005-06-23
申请人： ELEKTA AB (PUBL) , MINOZ, Alain , NIVESTEDT, Håkan
发明人： MINOZ, Alain , NIVESTEDT, Håkan
IPC分类号： A61N5/00
CPC分类号： A61N5/1084
摘要： The present invention relates to a collision detecting device for a radiation treatment apparatus, comprising a radiation unit (3) having an internal space, for directing radiation beams towards a radiological focus in the internal space for treatment of a target in a patient's body therein. The collision detecting device comprises a collision detecting unit (1) being electrically conductive at least on its outer surface and having a size slightly smaller than the internal space of the radiation unit, so as to be insertable into the internal space and held in an electrically insulating manner in respect of the radiation unit by spacer elements (5). The outer electrically conductive surface (2) is connectible to an electrical voltage supply (10) in order to detect if the outer surface of the collision detecting unit abuts against the inside surface of the radiation unit due to deformation or displacement of the collision detecting unit caused by the body part (7) or any equipment (6, 8) attached thereto. The invention also relates to a method for performing such collision detection.
摘要翻译：本发明涉及一种用于放射治疗设备的碰撞检测装置，包括具有内部空间的辐射单元（3），用于将辐射束引导到内部空间中的放射线焦点，用于治疗患者体内的靶。碰撞检测装置包括至少在其外表面上导电并且具有比辐射单元的内部空间略小的碰撞检测单元（1），以便能够插入到内部空间中并保持在电气通过间隔元件（5）相对于辐射单元的绝缘方式。外部导电表面（2）可连接到电压源（10），以便检测碰撞检测单元的外表面是否由于碰撞检测单元的变形或位移而与辐射单元的内表面抵接由身体部分（7）或与其连接的任何设备（6,8）引起。本发明还涉及一种用于执行这种碰撞检测的方法。

22. 发明申请

WO2005058419A1 COLLIMATOR SYSTEM FOR A RADIOTHERAPY APPARATUS 审中-公开
标题翻译：放射治疗装置的收缩系统
公开(公告)号：WO2005058419A1
公开(公告)日：2005-06-30
申请号：PCT/GB2004/005278
申请日：2004-12-16
申请人： ELEKTA AB (PUBL) , HULKES, Daniel
发明人： HULKES, Daniel
IPC分类号： A61N5/10
CPC分类号： A61N5/10 , A61N2005/1095 , G21K1/02
摘要： A collimator system for a radiation beam comprising a cassette containing at least one of a collimator and a filter and a housing for the cassette adapted to retain the cassette in a fixed relation with the radiation beam.
摘要翻译：一种用于辐射束的准直器系统，包括：包含准直器和过滤器中的至少一个的盒，以及用于盒的壳体，其适于将盒保持与辐射束成固定关系。

23. 发明申请

WO2004066211A1 IMAGING INTERNAL STRUCTURES 审中-公开
标题翻译：成像内部结构
公开(公告)号：WO2004066211A1
公开(公告)日：2004-08-05
申请号：PCT/GB2004/000155
申请日：2004-01-20
申请人： ELEKTA AB (PUBL) , LAMBERT, Zijp , BROWN, Kevin, John , JAFFRAY, David , SIEWERDSEN, Jeffrey , VAN HERK, Marcel , SONKE, Jan-Jakob
发明人： LAMBERT, Zijp , BROWN, Kevin, John , JAFFRAY, David , SIEWERDSEN, Jeffrey , VAN HERK, Marcel , SONKE, Jan-Jakob
IPC分类号： G06T7/00
CPC分类号： G06T5/009 , A61N5/1064 , G06T5/003 , G06T7/0016 , G06T7/20 , G06T11/005 , G06T2207/10081 , G06T2207/20068 , G06T2207/20192 , G06T2207/30061 , G06T2207/30096 , G06T2211/412
摘要： An apparatus, method and software module for selecting phase/correlated images from the output of a scanner such as a cone beam CT scanner operates by collapsing the images derived from the series from two dimensions to one dimension by summing the intensities of pixels along a dimension transverse to the one dimension, producing a further image from a composite of the one-dimensional images obtained from images in the series, analysing the further image for periodic patterns, and selecting from the series images having like phase in that periodic pattern. If desired, a plurality of reconstructions can be derived at different phases. The analysis of the further image for periodic patterns can include comparing the one-dimensional images therein, to identify a movement of features in that dimension. This allows (inter alia) the accurate determination of the breathing cycle in a patient and a concomitant improvement in the quality of CT scans by using phase-correlated images.
摘要翻译：用于从诸如锥形束CT扫描仪的扫描仪的输出中选择相位/相关图像的装置，方法和软件模块通过将沿着尺寸的像素的强度相加而将从二维衍生的图像从二维折叠到一维来进行操作横向于一个维度，从从该系列中的图像获得的一维图像的合成中产生另外的图像，分析另外的图像用于周期性图案，并从具有该周期性图案的类似相位的系列图像中进行选择。如果需要，可以在不同的阶段导出多个重建。对于周期性图案的另外的图像的分析可以包括比较其中的一维图像，以识别该维度中的特征的运动。这允许（特别地）通过使用相位相关图像来准确地确定患者的呼吸周期和伴随的CT扫描质量的改善。

24. 发明申请

WO2002100477A3 A RADIATION RECORDING DEVICE 审中-公开
公开(公告)号：WO2002100477A3
公开(公告)日：2002-12-19
申请号：PCT/SE2002/001070
申请日：2002-06-05
申请人： ELEKTA AB (publ) , NILSSON, Börje , ARNDT, Jürgen
发明人： NILSSON, Börje , ARNDT, Jürgen
IPC分类号： G01T1/29
摘要： A device for recording in at least two planes radiation from a radiotherapy apparatus in a limited area at which the radiation is directed. The device comprises a dimensionally stable frame (1) which is adapted to be arranged in a defined position relative to said radiotherapy apparatus, an attachment (4) on the frame (1) for a recording means, and a recording means (5) which extends from the attachment (4) at an acute angle to the frame (1) along an axis of rotation (6) and to the center of the frame (1). The recording means (5) is adapted to assume at least two defined rotational positions on said axis (6). In addition, the recording means (5) exhibits a surface (14) for supporting a radiation recording unit (13), which surface (14) is located in a plane (9) that forms an acute angle with the axis of rotation (6), the plane (9) of the surface (14) when rotating the recording means (5) being adapted to turn on a single pivot point (7) which is fixed relative to the frame (1).

25. 发明申请

WO2023072364A1 CONTINUUM RADIOTHERAPY TREATMENT PLANNING 审中-公开
公开(公告)号：WO2023072364A1
公开(公告)日：2023-05-04
申请号：PCT/EP2021/079551
申请日：2021-10-25
申请人： ELEKTA AB (PUBL)
发明人： SJOLUND, Jens Olof , NORDSTRÖM, Carl Axel Håkan
IPC分类号： A61N5/10 , G16H20/40
摘要： Systems and methods are disclosed for dynamic radiotherapy treatment planning in a continuous space of computation. Example operations for generating treatment plan data for a radiotherapy treatment include: obtaining data for a radiotherapy treatment of a human subject; generating a set of radiation controls from the data for the radiotherapy treatment, with at least one of the radiation controls being based on a mapping from a continuous (e.g., infinite dimensional) computational space; converting the generated set of radiation controls to a set of treatment delivery parameters, the set of treatment delivery parameters corresponding to capabilities of a radiotherapy treatment machine; and producing treatment plan data for the radiotherapy treatment based on the set of treatment delivery parameters.

26. 发明申请

WO2021121622A1 ADAPTIVE DOSE ACCUMULATION ALGORITHM 审中-公开
公开(公告)号：WO2021121622A1
公开(公告)日：2021-06-24
申请号：PCT/EP2019/086664
申请日：2019-12-20
申请人： ELEKTA AB (PUBL)
发明人： TILLY, David Andreas , KIMSTRAND, Peter , ERICSON, Petter , TILLY, Nina Terese
IPC分类号： G16H20/40 , G16H30/40
摘要： Techniques for adjusting radiotherapy treatment for a patient in real time are provided. The techniques include operations comprising: obtaining, during delivery of a radiotherapy treatment fraction to a patient, one or more images of the patient at a first rate; generating patient motion information at a second rate based on the one or more images obtained at the first rate; receiving, during delivery of the radiotherapy treatment fraction, radiotherapy treatment device settings at a third rate; computing, during delivery of the radiotherapy treatment fraction, dose delivered to the patient with a first level of accuracy based on the generated patient motion information and the radiotherapy treatment device settings; and determining, during delivery of the radiotherapy treatment fraction, a real-time measure of accumulated dose delivered to the patient with a second greater level of accuracy than the first level of accuracy using one or more prior dose computations.

27. 发明申请

WO2017093469A1 RADIOTHERAPY PLANNING SYSTEMS 审中-公开
标题翻译：放射治疗计划系统
公开(公告)号：WO2017093469A1
公开(公告)日：2017-06-08
申请号：PCT/EP2016/079560
申请日：2016-12-02
申请人： ELEKTA AB (PUBL)
发明人： SJÖLUND, Jens
IPC分类号： A61N5/10
CPC分类号： A61N5/1001 , A61N5/1031 , A61N5/1038 , A61N5/1039 , A61N5/1084
摘要： Existing radiotherapy treatment planning protocols treat a cancer as a fixed entity within a "target volume". Efforts have been directed towards faster or more accurate planning processes and more accurate or reliable delivery methods. We propose a treatment planning system for a radiotherapy apparatus comprising a computational processor applying a set of instructions to an input data set, the input data set comprising a three-dimensional dose distribution which is to be achieved by the radiotherapy apparatus within a volume to be irradiated, a three-dimensional volume image characterising the tissue types within the volume to be irradiated, and a set of apparatus parameters which characterise the radiotherapy apparatus, with the set of instructions including a computational process arranged to output a treatment plan apt to deliver the three-dimensional dose distribution when implemented by the radiotherapy apparatus, by optimising a function that includes at least one term representing a time-dependent response of the tissue types to an applied radiation. The set of instructions can then include a fractional distribution step arranged to assign fractional parts of the dose distribution to successive treatment fractions, taking into account time- and dose-dependent characteristics of the tissue types within the volume image, and the iterative computational process can then be arranged, for each non-identical fraction, to take into account the fractional part of the dose distribution and the set of apparatus parameters, to derive a set of treatment instructions apt to deliver the fractional part when carried out by the radiotherapy apparatus. The three-dimensional volume image will ideally characterise the tissue types according to at least their local chemical composition, to assist in modelling the dose response. The optimisation function can include terms representing time-dependent responses such as a cell repair model and a tumour diffusion model.
摘要翻译：现有的放射治疗计划方案将癌症视为“目标体积”内的固定实体。已经致力于更快或更准确的计划流程以及更准确或可靠的递送方法。我们提出了一种用于放射治疗装置的治疗计划系统，该系统包括将一组指令应用于输入数据集的计算处理器，该输入数据集包括三维剂量分布，该三维剂量分布将由放射治疗装置在要处理的体积内实现照射表征待照射的体积内的组织类型的三维体积图像以及表征放射治疗设备的一组设备参数，其中该组指令包括计算过程，该计算过程被设置为输出适合于将放射治疗设备通过优化包括表示组织类型对所施加的辐射的时间相关响应的至少一个项的函数来优化由放射治疗设备实现的三维剂量分布。然后该组指令可以包括分数分布步骤，该分数分布步骤被布置为考虑体积图像内的组织类型的时间和剂量依赖特性，将剂量分布的分数部分分配给连续的处理部分，并且迭代计算过程可以然后针对每个不相同的部分设置考虑剂量分布的小数部分和设备参数组，以得到当由放射治疗设备执行时适于递送小数部分的一组治疗指令。根据至少它们的局部化学组成，三维体积图像将理想地表征组织类型，以帮助建模剂量响应。优化功能可以包括表示与时间相关的响应的术语，例如细胞修复模型和肿瘤扩散模型。

28. 发明申请

WO2015118021A1 IMAGE GUIDED RADIOTHERAPY 审中-公开
标题翻译：图像指导放射治疗
公开(公告)号：WO2015118021A1
公开(公告)日：2015-08-13
申请号：PCT/EP2015/052322
申请日：2015-02-04
申请人： ELEKTA AB (PUBL)
发明人： CARLSSON, Per
IPC分类号： A61N5/10
CPC分类号： A61N5/1082 , A61N5/103 , A61N5/1049 , A61N5/1067 , A61N2005/1061
摘要： A table with 6 degrees of freedom is regarded as essential in order to adjust the patient position to correct for positioning errors and the like. However, this imposes a significant cost, has a redundant axis in a conventional linac treatment system, and adds to the volume of the table. We disclose a way of dealing with rotation of the patient in an axis about which the source has a limited range of rotation, without needing a rotational adjustment of the table. An apparatus comprises a radiotherapy delivery apparatus having a radiation source adapted to emit a beam of radiation and to rotate around at least one axis that intersects with the beam, the rotation being confined to a limited range of rotation, an associated imaging device, and a control means controlling both the source and the imaging device, together with a treatment planning computer that accepts an image of a patient and parameters defining the machine capabilities, and creates a treatment plan based on both, wherein the source is capable of rotation in that axis through a range of at least x degrees, and a parameter is passed to the treatment planning computer defining the source's available range as x-e where e>0 , and the control means is adapted to detect the patient position using the imaging device, determine a rotation r of the patient around the axis relative to the image used by the treatment planning computer, and if r compensate for the rotation by offsetting the source by a rotation equal to r . The limited range of rotation is typically less than 360 degrees although this need not necessarily be the case. An example of the type of radiotherapy apparatus to which this invention is applicable is shown in our earlier patent application WO2005/041774, but it can equally be applied to other types.
摘要翻译：被认为是具有6个自由度的表以便调整患者位置以校正定位误差等。然而，这带来了显着的成本，在常规线性加速器处理系统中具有冗余轴，并增加了表的体积。我们公开了一种处理患者旋转轴的方式，围绕该轴旋转源具有有限的旋转范围，而不需要对该台的旋转调节。一种装置包括放射治疗输送装置，其具有适于发射辐射束的辐射源，并围绕与光束相交的至少一个轴线旋转，旋转被限制在有限的旋转范围内，相关的成像装置和控制装置同时控制源和成像装置，以及接受患者图像的治疗计划计算机和定义机器能力的参数，并且基于两者创建治疗计划，其中源能够在该轴上旋转通过至少x度的范围，并且将参数传递到定义源的可用范围的治疗计划计算机作为xe，其中e> 0，并且控制装置适于使用成像装置检测患者位置，确定旋转 r相对于治疗计划计算机使用的图像在轴线周围，并且如果r

29. 发明申请

WO2013159787A1 RADIOTHERAPY APPARATUS 审中-公开
标题翻译：放射治疗仪
公开(公告)号：WO2013159787A1
公开(公告)日：2013-10-31
申请号：PCT/EP2012/001767
申请日：2012-04-25
申请人： ELEKTA AB (PUBL) , CHEN, Rui
发明人： CHEN, Rui
IPC分类号： A61N5/10
CPC分类号： A61N5/1049
摘要： Patients are told to keep still during radiotherapy treatment, but they receive no feedback as to their position during the treatment. We propose a process of active position correction by the patient, based on movement feedback to the patient. To this end, we provide a radiotherapy apparatus comprising a source of radiation, a patient support for locating a patient in the field of the source of radiation, a position detector for determining a position of a patient on the patient support, a comparator for comparing the output of the position detector with a predetermined position, and a feedback system for informing the patient of the output of the comparator. The feedback system can comprise a visual display, or an audible signal, or a haptic response, or any combination of these.
摘要翻译：告诉患者在放疗期间保持静止，但在治疗期间他们没有收到关于其位置的反馈。我们提出了一个基于对患者的运动反馈的患者主动位置矫正的过程。为此，我们提供一种包括辐射源的放射治疗装置，用于将患者定位在辐射源领域的患者支架，用于确定患者在患者支架上的位置的位置检测器，比较器具有预定位置的位置检测器的输出，以及用于向患者通知比较器的输出的反馈系统。反馈系统可以包括视觉显示或听觉信号，或触觉响应，或这些的任何组合。

30. 发明申请

WO2012146262A1 IMPROVEMENTS IN OR RELATING TO RADIOTHERAPY 审中-公开
标题翻译：改善或相关放射治疗
公开(公告)号：WO2012146262A1
公开(公告)日：2012-11-01
申请号：PCT/EP2011/002130
申请日：2011-04-28
申请人： ELEKTA AB (publ) , CLAESSON, Bengt Ake
发明人： CLAESSON, Bengt Ake
IPC分类号： A61N5/10
CPC分类号： A61N5/1045
摘要： Radiotherapy apparatus is disclosed, comprising a radiation source capable of emitting a beam of therapeutic radiation along a beam axis, collimation apparatus for delimiting the beam and comprising (i) a block of sufficient width to extend across the width of the beam, selectively movable into the beam from a first side of the beam axis, and (ii) an array of individually moveable elongate narrow leaves arranged side-by-side in a direction perpendicular to the beam, each being moveable longitudinally into the beam from a second and opposing side of the beam axis, in which there is no array of individually moveable elongate narrow leaves arranged side-by-side in a direction perpendicular to the beam moveable longitudinally into the beam from the first side of the beam axis. Thus, there is in effect a single bank of MLC leaves on one side of the aperture and a block collimator on the other. This is suitable for IMRT-based treatments. The block and the array of individually moveable elongate narrow leaves can be the only collimation apparatus in the head, offering weight reductions and height reductions relative to known radiation heads. The block can comprise an adjustable section defining its leading edge, capable of adjustment so as to vary the angle between the leading edge and the beam axis. This allows the leading edge of the block to be aligned to the local beam direction regardless of how far into the beam the block is positioned. This reduces the penumbra of the block and creates a better definition of the radiation field. Alternatively, the block can comprise a plurality of plates stacked in the direction of the beam axis and moveable relative to each other so that the leading edge of the thus-defined block is adjustable so as to vary the angle between the leading edge and the beam axis.
摘要翻译：公开了放射治疗装置，其包括能够沿着光束轴发射治疗辐射束的辐射源，用于限定光束的准直装置，并且包括（i）足够宽度的块以跨过光束的宽度延伸，可选择性地移动到所述光束从所述光束轴线的第一侧起，以及（ii）在垂直于所述光束的方向上并排布置的可单独移动的细长窄叶片的阵列，每个可从第二和相对侧纵向移动到所述光束中其中在垂直于梁的方向上并排设置有单独可移动的细长窄叶片阵列，该波束从波束轴线的第一侧纵向移动到波束中。因此，实际上，一个单一的MLC叶片在孔的一侧留下，另一个是块准直器。这适用于基于IMRT的治疗。可单独移动的细长窄叶片的块和阵列可以是头部中唯一的准直装置，相对于已知的辐射头提供减重和降低高度。该块可以包括限定其前缘的可调节部分，其能够进行调节，以改变前缘和梁轴线之间的角度。这允许块的前沿与局部波束方向对准，而不管块被定位到多远的多远。这减少了块的半影，并创建了更好的辐射场定义。或者，块可以包括沿着梁轴线的方向堆叠的多个板，并且可以相对于彼此移动，使得如此限定的块的前缘是可调节的，以便改变前缘和梁之间的角度轴。

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