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11. 发明申请

WO2015077559A1 CONFORMAL SENSOR SYSTEMS FOR SENSING AND ANALYSIS OF CARDIAC ACTIVITY 审中-公开
标题翻译：用于感染和分析心脏病活动的一致传感器系统
公开(公告)号：WO2015077559A1
公开(公告)日：2015-05-28
申请号：PCT/US2014/066810
申请日：2014-11-21
申请人： MC10, INC. , HUPPERT, Gilbert, Lee
发明人： HUPPERT, Gilbert, Lee , GHAFFARI, Roozbeh , CERUOLO, Melissa , KEEN, Bryan
IPC分类号： A61B5/00
CPC分类号： A61B5/6833 , A61B5/0006 , A61B5/0022 , A61B5/01 , A61B5/02028 , A61B5/0205 , A61B5/02055 , A61B5/02444 , A61B5/0408 , A61B5/04085 , A61B5/04087 , A61B5/0476 , A61B5/0488 , A61B5/08 , A61B5/4815 , A61B5/4839 , A61B5/486 , A61B5/4866 , A61B5/4875 , A61B5/7271 , A61B2560/0214 , A61B2560/0475 , A61B2562/0219 , A61B2562/08 , A61B2562/164 , A61M37/00
摘要： Systems, methods and apparatuses for monitoring cardiac activity of an individual using a conformal cardiac sensor device are presented herein. A conformal cardiac sensor device for analyzing cardiac activity includes a flexible substrate for coupling to the user, and a heart sensor component embedded on/in the substrate. The heart sensor component contacts a portion of the users skin and measures electrical variable(s) indicative of cardiac activity. A biometric sensor component is embedded on/in the flexible substrate and measures physiological variable(s) indicative of cardiac activity of the user. A microprocessor, which is embedded on/in the flexible substrate, is communicatively coupled to the heart sensor component and biometric sensor component and operable to execute microprocessor executable instructions for controlling the measurements of electrical data and physiological data. A wireless communication component is embedded on/in the flexible substrate and is operable to transmit data indicative of the measurements obtained by the sensor components.
摘要翻译：本文介绍了使用保形心脏传感器装置监测个体的心脏活动的系统，方法和装置。用于分析心脏活动的适形心脏传感器装置包括用于与用户耦合的柔性基底和嵌入在基底上的心脏传感器部件。心脏传感器组件接触用户皮肤的一部分并测量指示心脏活动的电变量。将生物测定传感器组件嵌入到柔性基底上/内，并测量指示使用者的心脏活动的生理变量。嵌入在柔性基板上的微处理器通信地耦合到心脏传感器部件和生物测定传感器部件，并可操作以执行用于控制电数据和生理数据的测量的微处理器可执行指令。无线通信部件被嵌入在柔性基板上/内部，并且可操作地传送指示由传感器部件获得的测量值的数据。

12. 发明申请

WO2015048323A2 EXTENDED WEAR ELECTROCARDIOGRAPHY PATCH USING INTERLACED WIRE ELECTRODES 审中-公开
标题翻译：使用交错线电极延长磨损的心电图贴片
公开(公告)号：WO2015048323A2
公开(公告)日：2015-04-02
申请号：PCT/US2014057511
申请日：2014-09-25
申请人： BARDY DIAGNOSTICS INC
发明人： FELIX JASON , BISHAY JON MIKALSON , BARDY GUST H
IPC分类号： A61B5/0402
CPC分类号： A61B5/0402 , A61B5/0408 , A61B5/04085 , A61B5/04087 , A61B5/04286 , A61B5/6833 , A61B2562/12 , A61B2562/164 , A61B2562/187 , A61B2562/247 , H01M2/1044 , H01M4/747
摘要： Physiological monitoring can be provided through a wearable monitor (12) that includes a flexible extended wear electrode patch (15) and a removable reusable monitor recorder (14). A pair of flexile wires (61, 71) is interlaced or sewn into a flexible backing (20), serving as electrode signal pickup and electrode circuit traces. The monitor (12) sits centrally on the patient's chest along the sternum (13), which significantly improves the ability to sense cutaneously cardiac electric signals, particularly those generated by the atrium. To counter the dislodgment due to compressional and torsional forces, non-irritating adhesive (43) is provided on the underside, or contact, surface of the electrode patch (15), but only on the distal (30) and proximal ends (31). Interlacing the flexile wires (61, 71) into the flexile backing (20) also provides structural support and malleability against compressional, tensile and torsional forces.
摘要翻译：可通过包括柔性延伸磨损电极贴片（15）和可移除可重复使用监视记录器（14）的可佩戴监视器（12）提供生理监视。一对柔性线（61,71）交织或缝合到柔性背衬（20）中，用作电极信号拾取器和电极电路迹线。监视器（12）沿着胸骨（13）居中地位于患者胸部，这显着提高了感知心脏电信号的能力，尤其是心房产生的电信号。为了克服由于压缩力和扭转力引起的移位，无刺激性粘合剂43设置在电极片15的下侧或接触表面上，但仅在远侧端部30和近侧端部31上提供，。将柔性线（61,71）交织到柔性背衬（20）中还提供了抗挤压，拉伸和扭转力的结构支撑和延展性。

13. 发明申请

WO2015002940A2 ADVANCED HEALTH MONITORING SYSTEM 审中-公开
标题翻译：先进的健康监测系统
公开(公告)号：WO2015002940A2
公开(公告)日：2015-01-08
申请号：PCT/US2014/045035
申请日：2014-07-01
申请人： MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
发明人： BRUCE, Charles, J. , FRIEDMAN, Paul, A. , SOMERS, Virend, K. , BENNET, Kevin, E.
IPC分类号： A61B5/04
CPC分类号： A61B5/0416 , A61B5/0002 , A61B5/02055 , A61B5/04085 , A61B5/04087 , A61B5/0478 , A61B5/0492 , A61B5/053 , A61B5/117 , A61B5/1171 , A61B5/14514 , A61B5/14551 , A61B5/4839 , A61B5/6833 , A61B5/684 , A61B5/7221 , A61B5/7246 , A61B5/7264 , A61B5/7275 , A61B5/746 , A61B2560/0412 , A61B2560/0456 , A61B2562/0219 , A61B2562/04 , A61B2562/06 , A61B2562/227
摘要： Devices and methods provided herein can enhance the operations and efficacy of a remote patient monitoring system. Such devices and methods include using a wearable monitoring device that may comprise non-invasive sensors as well as microsensors that are positioned subdermally in some embodiments. In some embodiments, the wearable health parameter monitoring devices include a disposable component and a reusable component that are electrically and mechanically coupled together to create a functioning monitor device.
摘要翻译：这里提供的设备和方法可以增强远程病人监护系统的操作和功效。这样的装置和方法包括使用可包括非侵入式传感器的可穿戴监测装置以及在一些实施例中在皮下定位的微传感器。在一些实施例中，可穿戴健康参数监测装置包括一次性部件和可重复使用部件，它们被电气地和机械地耦合在一起以创建功能监测装置。

14. 发明申请

WO2014143982A1 ELECTRODE WITH CHARGE-OPERATED INDICATOR 审中-公开
标题翻译：带电荷指示器的电极
公开(公告)号：WO2014143982A1
公开(公告)日：2014-09-18
申请号：PCT/US2014/028195
申请日：2014-03-14
申请人： WELCH ALLYN, INC.
发明人： LANE, John, A. , FREER, Benjamin , QUINN, David, E. , KROON, Frederik, W.
IPC分类号： A61B5/0408
CPC分类号： A61B5/04087 , A61B5/01 , A61B5/7221 , A61B5/74 , A61B2560/0462 , A61B2562/0257
摘要： An electrode includes separate first and second electrical contacts to contact the skin of a subject. A charge-holding structure is electrically connected between the first and second contacts. An indicator is operatively coupled to the charge-holding structure so that the indicator changes visibly in response to a change in the charge stored in the charge -holding structure. The electrode can include a rectifier across the contacts. A container for electrodes includes an electrical supply and a plurality of receptacles for electrodes so that a voltage difference is maintained across conductors of each receptacle (and contacts of an electrode therein) for at least one week. A method of making electrodes includes arranging the contacts over a support, connecting the charge-holding structure between them, arranging the indicator over the support, and charging the charge -holding structure so that the indicator has a first visual appearance.
摘要翻译：电极包括分开的第一和第二电触头以接触受试者的皮肤。电荷保持结构电连接在第一和第二触点之间。指示器可操作地耦合到电荷保持结构，使得指示符响应于存储在电荷保持结构中的电荷的变化而明显变化。电极可以包括穿过触点的整流器。用于电极的容器包括电源和用于电极的多个插座，使得在每个插座的导体（和其中的电极的触点）中保持电压差至少一周。制造电极的方法包括将触点布置在支撑件上，将电荷保持结构连接在它们之间，将指示器布置在支撑件上，并对电荷保持结构充电，使得指示器具有第一视觉外观。

15. 发明申请

WO2014116816A1 WIRELESS SENSOR PATCHES AND METHODS OF MANUFACTURING 审中-公开
标题翻译：无线传感器接口及其制造方法
公开(公告)号：WO2014116816A1
公开(公告)日：2014-07-31
申请号：PCT/US2014/012734
申请日：2014-01-23
申请人： AVERY DENNISON CORPORATION
发明人： ADAMS, James , ARMIJO, Edward, A. , HRUSKA, Ryan , ONDERISIN, Michael, R. , SILVESTRO, David
IPC分类号： A61B5/0408 , A61B5/053 , A61F13/02
CPC分类号： A61B5/04085 , A61B5/04087 , A61B5/0533 , A61B5/6833 , A61B2562/08 , A61B2562/12 , A61F13/00051
摘要： Wireless sensor patches include a skin-friendly adhesive and a flexible cover patch. In further examples, methods of manufacturing a plurality of wireless sensor patches include the step (I) of unwinding a flexible support membrane from a support membrane storage roll along an assembly path. The flexible support membrane is provided with a skin adhesive configured to mount a first face of the flexible support membrane to a skin surface. The method further comprises the step (II) of sequentially mounting a plurality of sensor devices with respect to a second face of the flexible support membrane along a longitudinal axis of the assembly path. The method further includes the step (III) of sequentially separating the flexible support membrane to provide the plurality of wireless sensor patches, wherein each wireless sensor patch includes a corresponding one of the plurality of sensor devices.
摘要翻译：无线传感器贴片包括皮肤友好的粘合剂和柔性盖子。在另外的实施例中，制造多个无线传感器贴片的方法包括沿着组装路径从支撑膜存储辊展开柔性支撑膜的步骤（I）。柔性支撑膜设置有皮肤粘合剂，其被配置为将柔性支撑膜的第一面安装到皮肤表面。该方法还包括步骤（II），其沿着组装路径的纵向轴线依次安装多个传感器装置相对于柔性支撑膜的第二面。该方法还包括顺序地分离柔性支撑膜以提供多个无线传感器贴片的步骤（III），其中每个无线传感器贴片包括多个传感器装置中相应的一个。

16. 发明申请

WO2014072582A1 ARRANGEMENT AND METHOD FOR CARRYING OUT ELECTRODE MEASUREMENTS 审中-公开
标题翻译：执行电极测量的装置和方法
公开(公告)号：WO2014072582A1
公开(公告)日：2014-05-15
申请号：PCT/FI2013/051054
申请日：2013-11-07
申请人： MEGA ELECTRONICS LTD
发明人： LAPPALAINEN, Reijo , MERVAALA, Esa , MYLLYMAA, Katja , MYLLYMAA, Sami , TÖYRÄS, Juha
IPC分类号： A61B5/0478 , A61B5/00 , A61B5/0408
CPC分类号： A61B5/0478 , A61B5/0408 , A61B5/04087 , A61B5/0496 , A61B5/6814 , A61B5/6823 , A61B5/6832 , A61B5/684 , A61B2562/0215 , A61B2562/046 , A61B2562/14 , A61B2562/164 , A61B2562/182
摘要： An arrangement for carrying out electrode measurements on the surface of the skin of a patient's head for recording the electrical activity of the brain comprises a matrix electrode configuration comprising a body part (100) of non-conductive material conforming to the contours of the surface of the skin. The arrangement comprises electrodes (102) for producing the measurement data connected to the said body part (100), means (104) for transmitting said measurement data and a measurement data unit for receiving sad measurement data for further processing. The body part (100) comprises an electrode placement configuration (108) for maintaining the mutual placements of the electrodes essentially the same with respect to one another and further comprises an active attachment surface (110) located between the electrodes (102) and the surface of the skin for forming a firm and electroconductive contact between the electrodes and the surface of the skin.
摘要翻译：用于在用于记录脑的电活动的患者头部皮肤表面上执行电极测量的装置包括矩阵电极构造，其包括符合表面等离子体的非导电材料的主体部分（100）皮。该装置包括用于产生连接到所述主体部分（100）的测量数据的电极（102），用于发送所述测量数据的装置（104）和用于接收难以测量数据以用于进一步处理的测量数据单元。主体部分（100）包括电极放置构造（108），用于将电极的相互放置保持彼此基本相同，并且还包括位于电极（102）和表面之间的主动附接表面（110）的皮肤，用于在电极和皮肤表面之间形成牢固且导电的接触。

17. 发明申请

WO2013181508A1 LONG TERM WEAR MULTIFUNCTION BIOMEDICAL ELECTRODE 审中-公开
标题翻译：长期磨损多功能生物医学电极
公开(公告)号：WO2013181508A1
公开(公告)日：2013-12-05
申请号：PCT/US2013/043565
申请日：2013-05-31
申请人： ZOLL MEDICAL CORPORATION
发明人： DUPELLE, Mary Ann , DESMARAIS, Christopher , TOTMAN, Mark
IPC分类号： A61N1/18 , A61N1/39 , C25B11/04
CPC分类号： A61N1/0496 , A61B5/04087 , A61B2562/17 , A61N1/046 , A61N1/0476
摘要： Electrodes, multi-electrode patches, and electrodes for biomedical systems are provided. The electrode includes an adhesive film layer having a top surface and a bottom surface. A conductive element is substantially surrounded by the adhesive film layer. A conductive gel layer covers at least portion of a surface of the conductive element. The conducting gel comprises a material that does not result in significant skin irritation on a human subject after a period of at least about one week.
摘要翻译：提供电极，多电极贴片和用于生物医学系统的电极。电极包括具有顶表面和底表面的粘合剂膜层。导电元件基本上被粘合膜层包围。导电凝胶层覆盖导电元件的表面的至少一部分。导电凝胶包含在至少约一周的时间之后不会对人类受试者造成明显皮肤刺激的材料。

18. 发明申请

WO2013010184A1 SENSOR DEVICE WITH FLEXIBLE JOINTS 审中-公开
标题翻译：带灵活接头的传感器设备
公开(公告)号：WO2013010184A1
公开(公告)日：2013-01-17
申请号：PCT/US2012/046967
申请日：2012-07-16
申请人： VERATHON INC. , CAPRIO, Matthew , BEASLEY, Vanessa , MCMORROW, Gerald , CLAY, Andrew , LADWIG, Jeffrey, William
发明人： CAPRIO, Matthew , BEASLEY, Vanessa , MCMORROW, Gerald , CLAY, Andrew , LADWIG, Jeffrey, William
IPC分类号： A61B5/00
CPC分类号： A61B5/6805 , A61B5/04085 , A61B5/04087 , A61B5/6823 , A61B5/6832 , A61B2562/0209 , A61B2562/04 , Y10T29/49128
摘要： A sensor device for monitoring bioelectric data from a human body includes a flexible dielectric substrate, a plurality of sensors (electrodes) distributed on the substrate for sensing the bioelectric data, and an electrically conductive network distributed on the substrate connecting the sensors to a terminal portion of the substrate. Integrated flexible joints permit a certain amount of elasticity in and allow relative movement between at least two of the sensors when the sensor device is placed onto the human body.
摘要翻译：一种用于从人体监测生物电数据的传感器装置包括柔性电介质基片，分布在基片上的多个传感器（电极），用于感测生物电数据;以及导电网络，分布在基片上，将传感器连接到终端部分的基底。当传感器装置放置在人体上时，集成的柔性接头允许一定量的弹性并允许至少两个传感器之间的相对运动。

19. 发明申请

WO2012011780A2 탈부착형 생체 신호 검측 패드 및 그것을 이용한 생체 신호 검측 장치 审中-公开
标题翻译：可拆卸的生物信号检测垫和使用其的生物信号检测装置
公开(公告)号：WO2012011780A2
公开(公告)日：2012-01-26
申请号：PCT/KR2011/005437
申请日：2011-07-22
申请人： 주식회사 유메딕스 , 우성훈
发明人： 우성훈
IPC分类号： A61B5/0408 , A61B5/0478 , A61B5/0492 , A61B5/02 , H04B7/24
CPC分类号： A61B5/6833 , A61B5/0002 , A61B5/0022 , A61B5/01 , A61B5/0205 , A61B5/02055 , A61B5/02438 , A61B5/0245 , A61B5/04 , A61B5/04087 , A61B5/0478 , A61B5/0492 , A61B5/14532 , A61B5/7203 , A61B5/7225
摘要： 맥박이나 체온과 같은 생체 신호를 간편하게 측정할 수 있는 탈부착형 생체 신호 검측 패드가 개시된다. 개시된 생체 신호 검측 패드는, 신체 탈부착이 가능한 점착성 패드 본체와, 본체의 신체 부착면에 마련된 생체 신호 감지용 전극 및, 전극과 연결되도록 본체에 설치되며 전극에서 측정된 생체 신호를 저장하는 메모리 카드가 내장된 모듈칩을 포함한다. 이러한 구성의 생체 신호 검측 패드는 휴대가 간편하여 언제 어디서든지 사용자가 간편하게 건강 상태를 측정할 수 있게 해주며, 또한 착탈이 가능한 메모리카드를 분석장비에 로딩하거나 또는 무선 통신을 이용해서 분석장비와 통신함으로써 그 측정 결과를 신속하게 활용할 수 있게 해주므로, 생체 신호의 신속한 검측과 활용이 가능해져서 건강 사회를 지키는데 큰 도움이 될 수 있다.
摘要翻译：＆lt; p num =“0000”＆gt;一种能够容易地测量诸如脉搏或体温的生物信号的可移除生物信号检测垫。所公开的生物信号检测垫被安装到所述主体，使得所述主体拆卸的粘合剂垫主体，和生物信号的感测电极，并且，连接到设置存储从所述电极测量到的生物信号，主体存储卡的主体连接表面上的电极包括一个嵌入式模块芯片。这种结构的生物信号检查焊盘是有助于能够携带，易于随时随地，用户容易地测量的健康状态，并且可拆卸地装载的存储卡到分析设备或分析设备以及使用所述无线通信的通信这使得快速利用测量结果并快速检测和利用生物信号成为可能，这对维持健康的社会有很大帮助。

20. 发明申请

WO2011056377A1 OFFSET ELECTRODE 审中-公开
标题翻译：偏置电极
公开(公告)号：WO2011056377A1
公开(公告)日：2011-05-12
申请号：PCT/US2010/052639
申请日：2010-10-14
申请人： ETHICON, INC. , BARE, Rex, O. , SARGENT, Bradley
发明人： BARE, Rex, O. , SARGENT, Bradley
IPC分类号： A61N1/04 , A61B5/0408 , A61N1/34 , A61N1/36
CPC分类号： A61N1/0456 , A61B5/04087 , A61B2562/125 , A61N1/0492 , A61N1/0496 , A61N1/36021
摘要： An electrode including a non-conductive substrate having a top surface and at least one channel extending therethrough, an electrically conductive trace material positioned adjacent a portion of the top surface of the non-conductive substrate and extending through the channel, and adapted for electrically coupling to a power source, and second and third electrically conductive materials that are inert or more corrosion resistant than the trace material. The second material is positioned adjacent to and entirely covering a top surface of the trace material, and the third material is positioned adjacent to and entirely covering a top surface of the second electrically conductive material, and covers a portion of a top surface of the non-conductive substrate surrounding the second electrically conductive material. The electrode further includes a conductive hydrogel positioned adjacent to a portion of a top surface of the third electrically conductive material, but laterally offset from the trace material.
摘要翻译：一种电极，包括具有顶表面和至少一个延伸穿过其中的通道的非导电基底，导电迹线材料定位成邻近非导电基底的顶表面的一部分并且延伸通过该通道，并适于电耦合电源，以及比微量材料更惰性或更耐腐蚀的第二和第三导电材料。第二材料定位成邻近并完全覆盖迹线材料的顶表面，并且第三材料被定位成与第二导电材料的顶表面相邻并且完全覆盖第二导电材料的顶表面，并覆盖非金属材料的顶表面的一部分导电基底包围第二导电材料。电极还包括邻近第三导电材料的顶表面的一部分定位的导电水凝胶，但是与痕量材料横向偏移。

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