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11. 发明申请

WO2006085253A3 COMPUTER TOMOGRAPHY APPARATUS, METHOD OF EXAMINING AN OBJECT OF INTEREST WITH A COMPUTER TOMOGRAPHY APPARATUS, COMPUTER-READABLE MEDIUM AND PROGRAM ELEMENT 审中-公开
公开(公告)号：WO2006085253A3
公开(公告)日：2006-08-17
申请号：PCT/IB2006/050374
申请日：2006-02-06
申请人： PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KONINKLIJKE PHILIPS ELECTRONICS N. V. , MANZKE, Robert , GRASS, Michael
发明人： MANZKE, Robert , GRASS, Michael
IPC分类号： A61B6/03
摘要： A computer tomography apparatus (100) for examination of a moving object of interest (130), comprising an electromagnetic radiation source (104) adapted to emit electromagnetic radiation to the object of interest (130) and adapted to rotate around the object of interest (130), detecting elements (123) adapted to detect electromagnetic radiation emitted by the electromagnetic radiation source (104) and passed through the object of interest (130), adapted to rotate around the object of interest (130) and adapted to detect first data related to a first motion interval of the object of interest (130) and to detect second data related to a second motion interval of the object of interest (130), and a determination unit (118) adapted to determine images of the structure of the object of interest (130) in the first motion interval and in the second motion interval and to determine motion information concerning the object of interest (130) between the first motion interval and the second motion interval based on an analysis of the determined images.

12. 发明申请

WO2006018763A1 COMPUTER TOMOGRAPHY SCANNER HAVING AN ADJUSTABLE ROTATIONAL SPEED 审中-公开
标题翻译：具有可调节旋转速度的计算机图形扫描仪
公开(公告)号：WO2006018763A1
公开(公告)日：2006-02-23
申请号：PCT/IB2005/052575
申请日：2005-08-02
申请人： PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KONINKLIJKE PHILIPS ELECTRONICS N. V. , MANZKE, Robert , GRASS, Michael , VAN STEVENDAAL, Udo
发明人： MANZKE, Robert , GRASS, Michael , VAN STEVENDAAL, Udo
IPC分类号： A61B6/03
CPC分类号： A61B6/035 , F16F15/28 , F16F15/36 , G01M1/36
摘要： The invention relates to a computer tomography scanner comprising a gantry, on the rotor of which one or more displaceable masses are arranged. During rotation of the rotor about a rotation axis, the position of each mass can be changed perpendicular to the rotation axis by means of an adjustment unit. By retaining the rotary momentum of the rotor, the rotational speed is increased when the masses are moved toward the rotation axis, and vice versa. As a result, it is possible to maintain a specific ratio between the heart rate of the examined patient and the rotational speed even if the heart rate of the patient changes during the examination.
摘要翻译：本发明涉及一种计算机断层摄影扫描器，其包括在其上布置有一个或多个可移位质量的转子上的台架。在转子围绕旋转轴线旋转期间，每个质量块的位置可以通过调整单元垂直于旋转轴线改变。通过保持转子的旋转动量，当质量朝向旋转轴线移动时，转速增加，反之亦然。结果，即使在检查期间患者的心率发生变化，也可以保持所检查患者的心率与转速之间的比率。

13. 发明申请

WO2005082253A1 DRUG APPLICATION DURING A CT SCAN 审中-公开
标题翻译： CT扫描期间的药物应用
公开(公告)号：WO2005082253A1
公开(公告)日：2005-09-09
申请号：PCT/IB2005/050576
申请日：2005-02-15
申请人： PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KONINKLIJKE PHILIPS ELECTRONICS N. V. , KOEHLER, Thomas , GRASS, Michael
发明人： KOEHLER, Thomas , GRASS, Michael
IPC分类号： A61B6/03
CPC分类号： A61B6/032 , A61B6/503 , A61B6/541 , A61B8/481
摘要： Controlled local application of drugs to a certain part of a body of a patient may be of major importance during a cardiac CT scan. By transporting the drugs in containers which prevent an application of the drugs and by rupturing only those containers which are located in the vicinity of the part of the body of a patient to which the drugs have to be applied, a local application of the drugs may be performed. According to an exemplary embodiment of the present invention, the rupturing and therefore the application of the drugs may be triggered by a monitoring algorithm which evaluates changes in the heart beat rate of the patient. Advantageously, the method allows for a local delivery of the drugs on a fine time scale and therefore for a fast control of the heart beat rate during the CT scan.
摘要翻译：在心脏CT扫描期间，将药物局部应用于患者身体的某一部分可能是非常重要的。通过将药物运送到容器中，以防止药物的使用，并且仅破坏那些位于药物必须施用的患者身体部分附近的容器，则药物的局部应用可以被执行。根据本发明的示例性实施例，药物的破裂和因此的应用可以由评估患者心跳速率变化的监测算法来触发。有利地，该方法允许在精细时间范围内局部递送药物，因此可以在CT扫描期间快速控制心跳率。

14. 发明申请

WO2005023114A3 COMPUTER TOMOGRAPHY METHOD USING A CONE-SHAPED BUNDLE OF RAYS 审中-公开
公开(公告)号：WO2005023114A3
公开(公告)日：2005-03-17
申请号：PCT/IB2004/051523
申请日：2004-08-23
申请人： PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KONINKLIJKE PHILIPS ELECTRONICS N. V. , BONTUS, Claas , KÖHLER, Thomas , GRASS, Michael
发明人： BONTUS, Claas , KÖHLER, Thomas , GRASS, Michael
IPC分类号： A61B6/03
摘要： The invention relates to a computer tomography method in which an examination area is passed through by a cone-shaped bundle of rays. The bundle of rays comes from a radiation source location which moves around the examination area on an overall trajectory. The overall trajectory consists of a first, closed partial trajectory, at least one second, closed partial trajectory and at least one third partial trajectory which connects the first and the at least one second partial trajectories to one another. Measured values which depend on the intensity in the bundle of rays on the other side of the examination area are acquired by means of a detector unit while the radiation source location is moving on the overall trajectory, and a CT image of the examination area is reconstructed from these measured values.

15. 发明申请

WO2010061328A1 VISUALIZATION OF THE CORONARY ARTERY TREE 审中-公开
标题翻译：冠状动脉瘤的可视化
公开(公告)号：WO2010061328A1
公开(公告)日：2010-06-03
申请号：PCT/IB2009/055220
申请日：2009-11-20
申请人： PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KONINKLIJKE PHILIPS ELECTRONICS N. V. , HANSIS, Eberhard, S. , GRASS, Michael
发明人： HANSIS, Eberhard, S. , GRASS, Michael
IPC分类号： A61B6/00 , G06T11/00
CPC分类号： A61B6/504 , A61B6/4441 , A61B6/466 , A61B6/481 , A61B6/541 , G06T11/006 , G06T2211/404
摘要： The present invention is related to a method for reconstruction of the coronary arteries and an examination apparatus for reconstruction of the coronary arteries. To provide improved coronary artery information, an apparatus and a method are provided where a gating signal is provided (32) and a first gated X-ray image sequence of one of the left or right branches of the coronary arteries is acquired (34) with injected contrast agent into the one of the left or right branches of the coronary arteries. Further, a second gated X-ray image sequence of the other branch of the coronary arteries is acquired (36) with injected contrast agent into said other branch. Then, a gated reconstructing (38) of the left and the right coronary artery is suggested and a volume data (40, 42) of the coronary arteries is generated. The volume data of the left and right coronary arteries is registered (44) in relation to time and space. Further; the registered volume data (48, 50) of the left and the right coronary arteries is combined and a combined coronary artery tree volume data set (52) is generated (54). Finally, the combined coronary tree volume data set is visualized (56).
摘要翻译：本发明涉及冠状动脉重建方法和冠状动脉重建检查装置。为了提供改善的冠状动脉信息，提供了一种装置和方法，其中提供门控信号（32），并且获取冠状动脉的左分支或右分支之一的第一门控X射线图像序列（34），其中将注射的造影剂注射到冠状动脉的左侧或右侧分支中。此外，冠状动脉的另一个分支的第二选通X射线图像序列（36）被注入造影剂获取到所述另一分支中。然后，建议左冠状动脉和右冠状动脉的门控重建（38），并且产生冠状动脉的体积数据（40,42）。左冠状动脉和右冠状动脉的体积数据相对于时间和空间被记录（44）。进一步; 组合左冠状动脉和右冠状动脉的记录体数据（48,50），并且生成组合冠状动脉树体积数据组（52）（54）。最后，组合冠状动脉树体数据集可视化（56）。

16. 发明申请

WO2010041201A1 ANGIOGRAPHIC IMAGE ACQUISITION SYSTEM AND METHOD WITH AUTOMATIC SHUTTER ADAPTATION FOR YIELDING A REDUCED FIELD OF VIEW COVERING A SEGMENTED TARGET STRUCTURE OR LESION FOR DECREASING X-RADIATION DOSE IN MINIMALLY INVASIVE X-RAY-GUIDED INTERVENTIONS 审中-公开
标题翻译：具有自动切换器适应性的图像摄影系统和方法用于屏蔽减少的视野范围在微小的X射线引导干预中减少X辐射剂量的分离的目标结构或损伤
公开(公告)号：WO2010041201A1
公开(公告)日：2010-04-15
申请号：PCT/IB2009/054381
申请日：2009-10-07
申请人： PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KONINKLIJKE PHILIPS ELECTRONICS N. V. , GRASS, Michael , SCHAEFER, Dirk , SCHOONENBERG, Gert, A., F.
发明人： GRASS, Michael , SCHAEFER, Dirk , SCHOONENBERG, Gert, A., F.
IPC分类号： A61B6/00 , A61B6/06
CPC分类号： G06T11/008 , A61B6/06 , A61B6/4441 , A61B6/481 , A61B6/504 , A61B6/5247 , A61B6/542 , G06F19/00 , G06F19/321 , G06T15/08 , G06T2211/404 , G16H40/63
摘要： The present invention refers to an angiographic image acquisition system and method which can beneficially be used in the scope of minimally invasive image-guided interventions. In particular, the present invention relates to a system and method for graphically visualizing a pre-interventionally virtual 3D representation of a patient's coronary artery tree's vessel segments in a region of interest of a patient's cardiovascular system to be three-dimensionally reconstructed. Optionally, this 3D representation can then be fused with an intraoperatively acquired fluoroscopic 2D live image of an interventional tool. According to the present invention, said method comprises the steps of subjecting the image data set of the 3D representation associated with the precalculated optimal viewing angle to a 3D segmentation algorithm (S4) in order to find the contours of a target structure or lesion to be examined and interventionally treated within a region of interest and automatically adjusting (S5) a collimator wedge position and/or aperture of a shutter mechanism used for collimating an X-ray beam emitted by an X-ray source of a C-arm-based 3D rotational angiography device or rotational gantry-based CT imaging system to which the patient is exposed during an image-guided radiographic examination procedure based on data obtained as a result of said segmentation which indicate the contour and size of said target structure or lesion. The aim is to reduce the region of interest to a field of view that covers said target structure or lesion together with a user-definable portion of the sorrounding vasculature.
摘要翻译：本发明涉及一种血管造影图像采集系统和方法，可有利地用于微创图像引导干预的范围。特别地，本发明涉及一种用于以图形方式可视化患者心血管系统感兴趣区域中的患者冠状动脉树血管段的预先介入虚拟3D表示以进行三维重构的系统和方法。可选地，该3D表示随后可以与介入工具的术中获取的荧光透视2D实况图像融合。根据本发明，所述方法包括以下步骤：将与预先计算的最佳视角相关联的3D表示的图像数据集进行3D分割算法（S4），以便找出目标结构或病变的轮廓为在感兴趣区域内进行检查和介入处理，并自动调整（S5）用于准直由基于C臂的3D的X射线源发射的X射线束的快门机构的准直器楔位置和/或孔径旋转血管造影装置或基于旋转台架的CT成像系统，其中基于由所述分割结果获得的指示所述目标结构或病变的轮廓和大小的图像引导放射线检查程序期间所述患者暴露于所述CT成像系统。目的是将感兴趣的区域减少到涵盖所述目标结构或病变的视野以及可疑的部分的迷路脉管系统。

17. 发明申请

WO2009024894A3 PROJECTION-BASED REMOVAL OF HIGH-CONTRAST OBJECTS 审中-公开
公开(公告)号：WO2009024894A3
公开(公告)日：2009-02-26
申请号：PCT/IB2008/053229
申请日：2008-08-12
申请人： PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KONINKLIJKE PHILIPS ELECTRONICS N. V. , JANDT, Uwe , SCHAEFER, Dirk , GRASS, Michael
发明人： JANDT, Uwe , SCHAEFER, Dirk , GRASS, Michael
IPC分类号： G06T7/00
摘要： A system (900) and method for automatic projection-based removing of high-contrast artificial objects from a medical image is provided. The method comprises performing a low-pass filtering (1100) to the two-dimensional image (100, 500, 1000) using a filter width range (1110) corresponding to structures of a line-shaped artificial object to generate a low-pass filtered intensity image and performing an evaluation of the Hessian matrix of each pixels of the low-pass filtered intensity image for locating and enhancing the structure of the line-shaped artificial object to generate a multi-scale filtered intensity image, wherein predefined scaling widths are used in order to avoid the locating and enhancing of larger structures.

18. 发明申请

WO2007072279A1 ITERATIVE IMAGE RECONSTRUCTION OF A MOVING OBJECT FROM PROJECTION DATA 审中-公开
标题翻译：投影数据移动对象的迭代图像重构
公开(公告)号：WO2007072279A1
公开(公告)日：2007-06-28
申请号：PCT/IB2006/054700
申请日：2006-12-08
申请人： PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KONINKLIJKE PHILIPS ELECTRONICS N. V. , NIELSEN, Tim , GRASS, Michael , ZIEGLER, Andy
发明人： NIELSEN, Tim , GRASS, Michael , ZIEGLER, Andy
IPC分类号： G06T11/00
CPC分类号： G06T11/006 , G06T2211/412 , G06T2211/424
摘要： Iterative methods for reconstructing an image sequence of a moving object based on projection data usually require a high computationally effort. According to embodiments of the present invention there is provided such a method wherein a first image representing the object at a first phase is used as an initial image for iteratively reconstructing a second image at a second phase. A first gating function is assigned to the first phase, a second gating function is assigned to the second phase. When executing a first iteration for reconstructing the second image only projection data corresponding to a non- overlapping part of the two gating functions are used. For executing further iterations the amount of projection data corresponding to the overlapping part of the two gating functions may be gradually increased. Therefore, for all further but the last iteration the computationally effort is significantly reduced. However, this low computationally expense has no negative impact on the quality of the finally reconstructed second image because the method benefits from the fact that the first image was used as the initial image for iteratively reconstructing the second image.
摘要翻译：基于投影数据重建移动物体的图像序列的迭代方法通常需要较高的计算量。根据本发明的实施例，提供了这样的方法，其中将表示第一阶段的对象的第一图像用作用于在第二阶段迭代重建第二图像的初始图像。第一门控功能被分配给第一阶段，第二门控功能被分配给第二阶段。当执行用于重建第二图像的第一迭代时，仅使用与两个门控功能的非重叠部分相对应的投影数据。为了执行进一步的迭代，对应于两个门控功能的重叠部分的投影数据的量可以逐渐增加。因此，对于所有进一步但最后的迭代，计算量的努力显着降低。然而，这种低的计算费用对最终重建的第二图像的质量没有负面影响，因为该方法受益于第一图像被用作用于迭代重建第二图像的初始图像的事实。

19. 发明申请

WO2006085242A1 COMPUTED TOMOGRAPHY METHOD WITH HELICAL RELATIVE MOVEMENT AND CONICAL BEAM BUNDLE 审中-公开
标题翻译：具有螺旋相对运动和锥形束的计算方法
公开(公告)号：WO2006085242A1
公开(公告)日：2006-08-17
申请号：PCT/IB2006/050332
申请日：2006-01-31
申请人： PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KONINKLIJKE PHILIPS ELECTRONICS N. V. , BONTUS, Claas , GRASS, Michael , KÖHLER, Thomas
发明人： BONTUS, Claas , GRASS, Michael , KÖHLER, Thomas
IPC分类号： G06T11/00
CPC分类号： G06T11/006 , A61B6/027 , G06T2211/421
摘要： The invention relates to a computed tomography method in which a periodically moving object is irradiated by a conical beam bundle. An n Pi-relative movement is generated between a radiation source, which generates the conical beam bundle, and the object. During the n Pi-relative movement, measured values are acquired, which depend on the intensity in the beam bundle on the other side of the object and from these measured values filter values are determined, which are divided into different groups. The filter values of at least one group are weighted in dependence on the movement of the object, wherein, when filter values of several groups are weighted, filter values of different groups are weighted differently in dependence on the movement of the object. Finally, a CT image of the object is reconstructed from the filter values.
摘要翻译：本发明涉及一种计算机断层摄影方法，其中周期性移动的物体被锥形束束照射。在产生锥形束束的辐射源和物体之间产生nPi相对运动。在nPi相对运动期间，获取测量值，其取决于对象另一侧上的束束中的强度，并且从这些测量值确定滤波器值，其被划分为不同的组。根据对象的移动对至少一个组的滤波器值进行加权，其中当对多个组的滤波器值进行加权时，根据对象的移动对不同组的滤波器值进行加权不同。最后，从过滤器值重建对象的CT图像。

20. 发明申请

WO2005057491A1 IMAGE SEGMENTATION IN A VOLUME DATA SET 审中-公开
标题翻译：体积数据集中的图像分割
公开(公告)号：WO2005057491A1
公开(公告)日：2005-06-23
申请号：PCT/IB2004/052569
申请日：2004-11-26
申请人： PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KONINKLIJKE PHILIPS ELECTRONICS N. V. , BUELOW, Thomas , GRASS, Michael , LORENZ, Christian , MANZKE, Robert
发明人： BUELOW, Thomas , GRASS, Michael , LORENZ, Christian , MANZKE, Robert
IPC分类号： G06T5/00
CPC分类号： G06T7/11 , G06T2207/10081 , G06T2207/30101
摘要： Coronary artery segmentation is a crucial task in cardiac CT image processing. This is often a tedious task performed manually by an operator. According to the present invention, a method is provided which combines data from multiple cardiac phases during the segmentation process in order to deliver a complete and continuous coronary vessel tree. Advantageously, this may allow for an improved visualization and segmentation of vessels, for example, in coronary CTA.
摘要翻译：冠状动脉分割是心脏CT图像处理中的关键任务。这通常是由操作员手动执行的繁琐的任务。根据本发明，提供了一种在分割过程中组合来自多个心脏相的数据以递送完整且连续的冠状动脉血管树的方法。有利地，这可以允许例如在冠状动脉CTA中改善血管的可视化和分割。

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